8gag - Revision history

OCA at 09:35, 1 March 2024

OCA — Fri, 01 Mar 2024 09:35:40 GMT

←Older revision		Revision as of 09:35, 1 March 2024
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-	'''Unreleased structure'''

-	~~The entry~~ 8gag ~~is ON HOLD until Paper Publication~~	+	==Cannabinoid receptor 1-Gi complex with novel ligand==
-		+	<StructureSection load='8gag' size='340' side='right'caption='[[8gag]], [[Resolution\|resolution]] 3.30Å' scene=''>
-	~~Authors~~: ~~Tummino, T~~.A.~~, Iliopoulos~~-~~Tsoutsouvas, C~~.~~, Braz, J~~.M.~~, O~~''~~Brien~~, E.S., ~~Krishna Kumar, K~~., ~~Makriyannis~~, M., ~~Basbaum, A~~.I., ~~Shoichet, B~~.K.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8gag]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GAG FirstGlance]. <br>
-	~~Description~~: ~~Cannabinoid receptor 1~~-~~Gi complex~~ with ~~novel ligand~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.3Å</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YVF:methyl+(2R)-2-({(1M)-5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonyl}amino)-2-(thiophen-2-yl)propanoate'>YVF</scene></td></tr>
-	[[Category: ~~Makriyannis, M~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gag OCA], [https://pdbe.org/8gag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gag RCSB], [https://www.ebi.ac.uk/pdbsum/8gag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gag ProSAT]</span></td></tr>
-	[[Category: ~~Tummino, T.A~~]]	+	</table>
-	[[Category: Basbaum~~, A.I~~]]	+	== Function ==
-	[[Category: Iliopoulos-Tsoutsouvas, C]]	+	[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
-	[[Category: ~~Shoichet, B.~~K]]	+	== References ==
-	[[Category: O''Brien~~, E.S~~]]	+	<references/>
-	[[Category: ~~Krishna Kumar, K~~]]	+	__TOC__
-	[[Category: ~~Braz, J.M~~]]	+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Mus musculus]]
		+	[[Category: Basbaum AI]]
		+	[[Category: Braz JM]]
		+	[[Category: Iliopoulos-Tsoutsouvas C]]
		+	[[Category: Krishna Kumar K]]
		+	[[Category: Makriyannis M]]
		+	[[Category: O'Brien ES]]
		+	[[Category: Shoichet BK]]
		+	[[Category: Tummino TA]]

OCA at 05:07, 7 February 2024

OCA — Wed, 07 Feb 2024 05:07:04 GMT

←Older revision		Revision as of 05:07, 7 February 2024
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8gag is ON HOLD	+	The entry 8gag is ON HOLD until Paper Publication

	Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., Shoichet, B.K.		Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., Shoichet, B.K.
Line 7:		Line 7:
	Description: Cannabinoid receptor 1-Gi complex with novel ligand		Description: Cannabinoid receptor 1-Gi complex with novel ligand
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: O''Brien, E.S]]
-	[[Category: Basbaum, A.I]]
	[[Category: Makriyannis, M]]		[[Category: Makriyannis, M]]
	[[Category: Tummino, T.A]]		[[Category: Tummino, T.A]]
-	[[Category: ~~Krishna Kumar~~, ~~K]]~~	+	[[Category: Basbaum, A.I]]
-	~~[[Category: Braz, J~~.M]]	+
	[[Category: Iliopoulos-Tsoutsouvas, C]]		[[Category: Iliopoulos-Tsoutsouvas, C]]
	[[Category: Shoichet, B.K]]		[[Category: Shoichet, B.K]]
		+	[[Category: O''Brien, E.S]]
		+	[[Category: Krishna Kumar, K]]
		+	[[Category: Braz, J.M]]

OCA at 08:43, 20 December 2023

OCA — Wed, 20 Dec 2023 08:43:47 GMT

←Older revision		Revision as of 08:43, 20 December 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8gag is ON HOLD ~~until Paper Publication~~	+	The entry 8gag is ON HOLD

	Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., Shoichet, B.K.		Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., Shoichet, B.K.
Line 7:		Line 7:
	Description: Cannabinoid receptor 1-Gi complex with novel ligand		Description: Cannabinoid receptor 1-Gi complex with novel ligand
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: O''Brien, E.S]]
		+	[[Category: Basbaum, A.I]]
	[[Category: Makriyannis, M]]		[[Category: Makriyannis, M]]
	[[Category: Tummino, T.A]]		[[Category: Tummino, T.A]]
-	[[Category: Basbaum, A.I]]
-	[[Category: Iliopoulos-Tsoutsouvas, C]]
-	[[Category: Shoichet, B.K]]
-	[[Category: O''Brien, E.S]]
	[[Category: Krishna Kumar, K]]		[[Category: Krishna Kumar, K]]
	[[Category: Braz, J.M]]		[[Category: Braz, J.M]]
		+	[[Category: Iliopoulos-Tsoutsouvas, C]]
		+	[[Category: Shoichet, B.K]]

OCA at 05:45, 8 March 2023

OCA — Wed, 08 Mar 2023 05:45:37 GMT

←Older revision		Revision as of 05:45, 8 March 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8gag is ON HOLD	+	The entry 8gag is ON HOLD until Paper Publication

	Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., Shoichet, B.K.		Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., Shoichet, B.K.
Line 8:		Line 8:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Makriyannis, M]]		[[Category: Makriyannis, M]]
		+	[[Category: Tummino, T.A]]
	[[Category: Basbaum, A.I]]		[[Category: Basbaum, A.I]]
		+	[[Category: Iliopoulos-Tsoutsouvas, C]]
	[[Category: Shoichet, B.K]]		[[Category: Shoichet, B.K]]
	[[Category: O''Brien, E.S]]		[[Category: O''Brien, E.S]]
	[[Category: Krishna Kumar, K]]		[[Category: Krishna Kumar, K]]
	[[Category: Braz, J.M]]		[[Category: Braz, J.M]]
-	[[Category: Tummino, T.A]]
-	[[Category: Iliopoulos-Tsoutsouvas, C]]

OCA: Protected "8gag" [edit=sysop:move=sysop]

OCA — Thu, 02 Mar 2023 04:33:46 GMT

Protected "8gag" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:33, 2 March 2023

OCA: New page: '''Unreleased structure''' The entry 8gag is ON HOLD Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., S...

OCA — Thu, 02 Mar 2023 04:33:45 GMT

New page: '''Unreleased structure''' The entry 8gag is ON HOLD Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., S...

New page

'''Unreleased structure'''

The entry 8gag is ON HOLD

Authors: Tummino, T.A., Iliopoulos-Tsoutsouvas, C., Braz, J.M., O''Brien, E.S., Krishna Kumar, K., Makriyannis, M., Basbaum, A.I., Shoichet, B.K.

Description: Cannabinoid receptor 1-Gi complex with novel ligand
[[Category: Unreleased Structures]]
[[Category: Makriyannis, M]]
[[Category: Basbaum, A.I]]
[[Category: Shoichet, B.K]]
[[Category: O''Brien, E.S]]
[[Category: Krishna Kumar, K]]
[[Category: Braz, J.M]]
[[Category: Tummino, T.A]]
[[Category: Iliopoulos-Tsoutsouvas, C]]