8gsx - Revision history

OCA at 19:49, 29 May 2024

OCA — Wed, 29 May 2024 19:49:54 GMT

←Older revision		Revision as of 19:49, 29 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8gsx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_str._13 Clostridium perfringens str. 13]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GSX FirstGlance]. <br>		<table><tr><td colspan='2'>[[8gsx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_str._13 Clostridium perfringens str. 13]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GSX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.86Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gsx OCA], [https://pdbe.org/8gsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gsx RCSB], [https://www.ebi.ac.uk/pdbsum/8gsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gsx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gsx OCA], [https://pdbe.org/8gsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gsx RCSB], [https://www.ebi.ac.uk/pdbsum/8gsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gsx ProSAT]</span></td></tr>
	</table>		</table>

OCA at 05:42, 7 June 2023

OCA — Wed, 07 Jun 2023 05:42:23 GMT

←Older revision		Revision as of 05:42, 7 June 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8gsx is ~~ON HOLD until Paper~~ Publication	+	==X-ray structure of Clostridium perfringens pili protein B collagen-binding domains==
		+	<StructureSection load='8gsx' size='340' side='right'caption='[[8gsx]], [[Resolution\|resolution]] 2.86Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8gsx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_str._13 Clostridium perfringens str. 13]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GSX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gsx OCA], [https://pdbe.org/8gsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gsx RCSB], [https://www.ebi.ac.uk/pdbsum/8gsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gsx ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8XP11_CLOPE Q8XP11_CLOPE]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sortase-mediated pili are flexible rod proteins composed of major and minor/tip pilins, playing important roles in the initial adhesion of bacterial cells to host tissues. The pilus shaft is formed by covalent polymerization of major pilins, and the minor/tip pilin is covalently attached to the tip of the shaft involved in adhesion to the host cell. The Gram-positive bacterium Clostridium perfringens has a major pilin, and a minor/tip pilin (CppB) with the collagen-binding motif. Here, we report X-ray structures of CppB collagen-binding domains, collagen-binding assays and mutagenesis analysis, demonstrating that CppB collagen-binding domains adopt an L-shaped structure in open form, and that a small beta-sheet unique to CppB provides a scaffold for a favourable binding site for collagen peptide.

-	~~Authors: Kamitori, S~~., ~~Yamada~~, M., ~~Tamai~~, E.	+	Structural and biochemical characterization of Clostridium perfringens pili protein B collagen-binding domains.,Tamai E, Yamada M, Ishida T, Arimura N, Matsunami R, Sekiya H, Kamitori S FEBS Lett. 2023 May;597(10):1345-1354. doi: 10.1002/1873-3468.14626. Epub 2023 , Apr 27. PMID:37071018<ref>PMID:37071018</ref>

-	~~Description: X-ray structure~~ of Clostridium perfringens ~~pili protein B collagen-binding domains~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: ~~Yamada, M~~]]	+	<div class="pdbe-citations 8gsx" style="background-color:#fffaf0;"></div>
-	[[Category: Tamai, E]]	+	== References ==
-	[[Category: ~~Kamitori, S~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Clostridium perfringens str. 13]]
		+	[[Category: Large Structures]]
		+	[[Category: Kamitori S]]
		+	[[Category: Tamai E]]
		+	[[Category: Yamada M]]

OCA: Protected "8gsx" [edit=sysop:move=sysop]

OCA — Wed, 14 Sep 2022 05:55:51 GMT

Protected "8gsx" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:55, 14 September 2022

OCA: New page: '''Unreleased structure''' The entry 8gsx is ON HOLD until Paper Publication Authors: Kamitori, S., Yamada, M., Tamai, E. Description: X-ray structure of Clostridium perfringens pili p...

OCA — Wed, 14 Sep 2022 05:55:50 GMT

New page: '''Unreleased structure''' The entry 8gsx is ON HOLD until Paper Publication Authors: Kamitori, S., Yamada, M., Tamai, E. Description: X-ray structure of Clostridium perfringens pili p...

New page

'''Unreleased structure'''

The entry 8gsx is ON HOLD until Paper Publication

Authors: Kamitori, S., Yamada, M., Tamai, E.

Description: X-ray structure of Clostridium perfringens pili protein B collagen-binding domains
[[Category: Unreleased Structures]]
[[Category: Yamada, M]]
[[Category: Tamai, E]]
[[Category: Kamitori, S]]