8hhf - Revision history

OCA at 17:38, 18 October 2023

OCA — Wed, 18 Oct 2023 17:38:37 GMT

←Older revision		Revision as of 17:38, 18 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8hhf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HHF FirstGlance]. <br>		<table><tr><td colspan='2'>[[8hhf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HHF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hhf OCA], [https://pdbe.org/8hhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hhf RCSB], [https://www.ebi.ac.uk/pdbsum/8hhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hhf ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.04Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hhf OCA], [https://pdbe.org/8hhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hhf RCSB], [https://www.ebi.ac.uk/pdbsum/8hhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hhf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:09, 26 April 2023

OCA — Wed, 26 Apr 2023 17:09:19 GMT

←Older revision		Revision as of 17:09, 26 April 2023
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-	'''Unreleased structure'''

-	The ~~entry~~ 8hhf is ~~ON HOLD until Paper~~ Publication	+	==The bacterial divisome protein complex FtsB-FtsL-FtsQ==
		+	<StructureSection load='8hhf' size='340' side='right'caption='[[8hhf]], [[Resolution\|resolution]] 3.04Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8hhf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HHF FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hhf OCA], [https://pdbe.org/8hhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hhf RCSB], [https://www.ebi.ac.uk/pdbsum/8hhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hhf ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/J7Q602_ECOLX J7Q602_ECOLX] Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.[HAMAP-Rule:MF_00911]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The synthesis of the cell-wall peptidoglycan during bacterial cell division is mediated by a multiprotein machine, called the divisome. The essential membrane protein complex of FtsB, FtsL and FtsQ (FtsBLQ) is at the heart of the divisome assembly cascade in Escherichia coli. This complex regulates the transglycosylation and transpeptidation activities of the FtsW-FtsI complex and PBP1b via coordination with FtsN, the trigger for the onset of constriction. Yet the underlying mechanism of FtsBLQ-mediated regulation is largely unknown. Here, we report the full-length structure of the heterotrimeric FtsBLQ complex, which reveals a V-shaped architecture in a tilted orientation. Such a conformation could be strengthened by the transmembrane and the coiled-coil domains of the FtsBL heterodimer, as well as an extended beta-sheet of the C-terminal interaction site involving all three proteins. This trimeric structure may also facilitate interactions with other divisome proteins in an allosteric manner. These results lead us to propose a structure-based model that delineates the mechanism of the regulation of peptidoglycan synthases by the FtsBLQ complex.

-	~~Authors~~:	+	Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome.,Nguyen HTV, Chen X, Parada C, Luo AC, Shih O, Jeng US, Huang CY, Shih YL, Ma C Nat Commun. 2023 Apr 5;14(1):1903. doi: 10.1038/s41467-023-37543-4. PMID:37019934<ref>PMID:37019934</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 8hhf" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Escherichia coli]]
		+	[[Category: Large Structures]]
		+	[[Category: Chen X]]
		+	[[Category: Nguyen VHT]]

OCA at 05:55, 7 December 2022

OCA — Wed, 07 Dec 2022 05:55:42 GMT

←Older revision		Revision as of 05:55, 7 December 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8hhf is ON HOLD	+	The entry 8hhf is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8hhf" [edit=sysop:move=sysop]

OCA — Thu, 24 Nov 2022 08:28:59 GMT

Protected "8hhf" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:28, 24 November 2022

OCA: New page: '''Unreleased structure''' The entry 8hhf is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 24 Nov 2022 08:28:57 GMT

New page: '''Unreleased structure''' The entry 8hhf is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8hhf is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]