OCA at 07:28, 22 November 2023

OCA — Wed, 22 Nov 2023 07:28:34 GMT

←Older revision		Revision as of 07:28, 22 November 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8hin is ~~ON HOLD until 2024~~-~~11-21~~	+	==Structure of human SGLT2-MAP17 complex with Phlorizin==
-		+	<StructureSection load='8hin' size='340' side='right'caption='[[8hin]], [[Resolution\|resolution]] 3.30Å' scene=''>
-	~~Authors~~: ~~Masahiro~~, H., ~~Hioryuki~~, K., ~~Ikuko~~, M., ~~Osamu~~, N.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8hin]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HIN FirstGlance]. <br>
-	~~Description~~: ~~Structure of human SGLT2~~-~~MAP17 complex~~ with ~~Phlorizin~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.3Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LN9:1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one'>LN9</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	[[Category: Hioryuki, K]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hin OCA], [https://pdbe.org/8hin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hin RCSB], [https://www.ebi.ac.uk/pdbsum/8hin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hin ProSAT]</span></td></tr>
-	[[Category: ~~Masahiro, H~~]]	+	</table>
-	[[Category: ~~Ikuko, M~~]]	+	== Disease ==
-	[[Category: Osamu, N]]	+	[https://www.uniprot.org/uniprot/SC5A2_HUMAN SC5A2_HUMAN] Familial renal glucosuria. The disease is caused by variants affecting the gene represented in this entry.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SC5A2_HUMAN SC5A2_HUMAN] Electrogenic Na(+)-coupled sugar simporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump (PubMed:20980548, PubMed:28592437, PubMed:34880493). Has a primary role in D-glucose reabsorption from glomerular filtrate across the brush border of the early proximal tubules of the kidney (By similarity).[UniProtKB:Q923I7]<ref>PMID:20980548</ref> <ref>PMID:28592437</ref> <ref>PMID:34880493</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Hioryuki K]]
		+	[[Category: Ikuko M]]
		+	[[Category: Masahiro H]]
		+	[[Category: Osamu N]]

OCA at 06:06, 11 January 2023

OCA — Wed, 11 Jan 2023 06:06:13 GMT

←Older revision		Revision as of 06:06, 11 January 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8hin is ON HOLD	+	The entry 8hin is ON HOLD until 2024-11-21

	Authors: Masahiro, H., Hioryuki, K., Ikuko, M., Osamu, N.		Authors: Masahiro, H., Hioryuki, K., Ikuko, M., Osamu, N.

OCA: Protected "8hin" [edit=sysop:move=sysop]

OCA — Wed, 30 Nov 2022 08:49:49 GMT

Protected "8hin" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:49, 30 November 2022

OCA: New page: '''Unreleased structure''' The entry 8hin is ON HOLD Authors: Masahiro, H., Hioryuki, K., Ikuko, M., Osamu, N. Description: Structure of human SGLT2-MAP17 complex with Phlorizin [[Cate...

OCA — Wed, 30 Nov 2022 08:49:48 GMT

New page: '''Unreleased structure''' The entry 8hin is ON HOLD Authors: Masahiro, H., Hioryuki, K., Ikuko, M., Osamu, N. Description: Structure of human SGLT2-MAP17 complex with Phlorizin [[Cate...

New page

'''Unreleased structure'''

The entry 8hin is ON HOLD

Authors: Masahiro, H., Hioryuki, K., Ikuko, M., Osamu, N.

Description: Structure of human SGLT2-MAP17 complex with Phlorizin
[[Category: Unreleased Structures]]
[[Category: Hioryuki, K]]
[[Category: Masahiro, H]]
[[Category: Ikuko, M]]
[[Category: Osamu, N]]

8hin - Revision history

OCA at 07:28, 22 November 2023

OCA at 06:06, 11 January 2023

OCA: Protected "8hin" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8hin is ON HOLD Authors: Masahiro, H., Hioryuki, K., Ikuko, M., Osamu, N. Description: Structure of human SGLT2-MAP17 complex with Phlorizin [[Cate...