8hnl - Revision history

OCA at 08:01, 1 May 2024

OCA — Wed, 01 May 2024 08:01:45 GMT

←Older revision		Revision as of 08:01, 1 May 2024
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	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>		[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
		+
		+	==See Also==
		+	*[[Transducin 3D structures\|Transducin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:56, 29 November 2023

OCA — Wed, 29 Nov 2023 13:56:37 GMT

←Older revision		Revision as of 13:56, 29 November 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8hnl is ~~ON HOLD until Paper Publication~~	+	==CXCR3-DNGi complex activated by PS372424==
-		+	<StructureSection load='8hnl' size='340' side='right'caption='[[8hnl]], [[Resolution\|resolution]] 2.98Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8hnl]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oplophorus_gracilirostris Oplophorus gracilirostris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HNL FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.98Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4AI:(3S)-N-[(2S)-5-carbamimidamido-1-(cyclohexylmethylamino)-1-oxidanylidene-pentan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide'>4AI</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hnl OCA], [https://pdbe.org/8hnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hnl RCSB], [https://www.ebi.ac.uk/pdbsum/8hnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hnl ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Escherichia coli]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Oplophorus gracilirostris]]
		+	[[Category: Hu HL]]
		+	[[Category: Jiao HZ]]

OCA at 06:08, 11 January 2023

OCA — Wed, 11 Jan 2023 06:08:47 GMT

←Older revision		Revision as of 06:08, 11 January 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8hnl is ON HOLD	+	The entry 8hnl is ON HOLD until Paper Publication

-	Authors: ~~Jiao, H.Z., Hu, H.L.~~	+	Authors:

-	Description: ~~CXCR3-DNGi complex activated by PS372424~~	+	Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Jiao, H.Z]]
-	[[Category: Hu, H.L]]

OCA: Protected "8hnl" [edit=sysop:move=sysop]

OCA — Wed, 14 Dec 2022 08:05:40 GMT

Protected "8hnl" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:05, 14 December 2022

OCA: New page: '''Unreleased structure''' The entry 8hnl is ON HOLD Authors: Jiao, H.Z., Hu, H.L. Description: CXCR3-DNGi complex activated by PS372424 Category: Unreleased Structures [[Category:...

OCA — Wed, 14 Dec 2022 08:05:37 GMT

New page: '''Unreleased structure''' The entry 8hnl is ON HOLD Authors: Jiao, H.Z., Hu, H.L. Description: CXCR3-DNGi complex activated by PS372424 Category: Unreleased Structures [[Category:...

New page

'''Unreleased structure'''

The entry 8hnl is ON HOLD

Authors: Jiao, H.Z., Hu, H.L.

Description: CXCR3-DNGi complex activated by PS372424
[[Category: Unreleased Structures]]
[[Category: Jiao, H.Z]]
[[Category: Hu, H.L]]