8hut - Revision history

OCA at 08:22, 7 February 2024

OCA — Wed, 07 Feb 2024 08:22:19 GMT

←Older revision		Revision as of 08:22, 7 February 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8hut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HUT FirstGlance]. <br>		<table><tr><td colspan='2'>[[8hut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HUT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7YY:6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione'>7YY</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.98Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7YY:6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione'>7YY</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hut OCA], [https://pdbe.org/8hut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hut RCSB], [https://www.ebi.ac.uk/pdbsum/8hut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hut ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hut OCA], [https://pdbe.org/8hut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hut RCSB], [https://www.ebi.ac.uk/pdbsum/8hut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hut ProSAT]</span></td></tr>
	</table>		</table>

OCA at 09:40, 21 June 2023

OCA — Wed, 21 Jun 2023 09:40:37 GMT

←Older revision		Revision as of 09:40, 21 June 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8hut is ~~ON HOLD until 2024~~-12-24	+	==Crystal structure of MERS main protease in complex with S217622==
-		+	<StructureSection load='8hut' size='340' side='right'caption='[[8hut]], [[Resolution\|resolution]] 1.98Å' scene=''>
-	~~Authors~~: ~~Lin~~, C., ~~Zhang~~, J., Li, J.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8hut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HUT FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of ~~MERS main protease in complex with S217622~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7YY:6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione'>7YY</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hut OCA], [https://pdbe.org/8hut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hut RCSB], [https://www.ebi.ac.uk/pdbsum/8hut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hut ProSAT]</span></td></tr>
-	[[Category: ~~Lin, C~~]]	+	</table>
-	[[Category: Li, J]]	+	== Function ==
-	[[Category: Zhang, J]]	+	[https://www.uniprot.org/uniprot/T2B9I2_MERS T2B9I2_MERS] Catalytic subunit of viral RNA capping enzyme which catalyzes the RNA guanylyltransferase reaction for genomic and sub-genomic RNAs. The kinase-like NiRAN domain of NSP12 transfers RNA to the amino terminus of NSP9, forming a covalent RNA-protein intermediate. Subsequently, the NiRAN domain transfers RNA to GDP, forming the core cap structure GpppA-RNA. The NSP14 and NSP16 methyltransferases then add methyl groups to form functional cap structures.[ARBA:ARBA00034461]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Middle East respiratory syndrome-related coronavirus]]
		+	[[Category: Li J]]
		+	[[Category: Lin C]]
		+	[[Category: Zhang J]]

OCA at 08:53, 15 February 2023

OCA — Wed, 15 Feb 2023 08:53:47 GMT

←Older revision		Revision as of 08:53, 15 February 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8hut is ON HOLD	+	The entry 8hut is ON HOLD until 2024-12-24

	Authors: Lin, C., Zhang, J., Li, J.		Authors: Lin, C., Zhang, J., Li, J.

OCA: Protected "8hut" [edit=sysop:move=sysop]

OCA — Wed, 11 Jan 2023 06:11:42 GMT

Protected "8hut" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:11, 11 January 2023

OCA: New page: '''Unreleased structure''' The entry 8hut is ON HOLD Authors: Lin, C., Zhang, J., Li, J. Description: Crystal structure of MERS main protease in complex with S217622 [[Category: Unrele...

OCA — Wed, 11 Jan 2023 06:11:41 GMT

New page: '''Unreleased structure''' The entry 8hut is ON HOLD Authors: Lin, C., Zhang, J., Li, J. Description: Crystal structure of MERS main protease in complex with S217622 [[Category: Unrele...

New page

'''Unreleased structure'''

The entry 8hut is ON HOLD

Authors: Lin, C., Zhang, J., Li, J.

Description: Crystal structure of MERS main protease in complex with S217622
[[Category: Unreleased Structures]]
[[Category: Lin, C]]
[[Category: Li, J]]
[[Category: Zhang, J]]