OCA at 11:42, 1 February 2024

OCA — Thu, 01 Feb 2024 11:42:50 GMT

←Older revision		Revision as of 11:42, 1 February 2024
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-	'''Unreleased structure'''

-	~~The entry~~ 8jai is ~~ON HOLD~~	+	==Crystal Structure of Human H-Ferritin variant 123F assembling in solution 1==
		+	<StructureSection load='8jai' size='340' side='right'caption='[[8jai]], [[Resolution\|resolution]] 2.56Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8jai]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JAI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JAI FirstGlance]. <br>
		+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.56Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jai FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jai OCA], [https://pdbe.org/8jai PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jai RCSB], [https://www.ebi.ac.uk/pdbsum/8jai PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jai ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein lattices that shift the structure and shape anisotropy in response to environmental cues are closely coupled to potential functionality. However, to design and construct shape-anisotropic protein arrays from the same building blocks in response to different external stimuli remains challenging. Here, by a combination of the multiple, symmetric interaction sites on the outer surface of protein nanocages and the tunable features of phenylalanine-phenylalanine interactions, a protein engineering approach is reported to construct a variety of superstructures with shape anisotropy, including 3D cubic, 2D hexagonal layered, and 1D rod-like crystalline protein nanocage arrays by using one single protein building block. Notably, the assembly of these crystalline protein arrays is reversible, which can be tuned by external stimuli (pH and ionic strength). The anisotropic morphologies of the fabricated macroscopic crystals can be correlated with the A-to-nm scale protein arrangement details by crystallographic elucidation. These results enhance the understanding of the freedom offered by an object's symmetry and inter-object pi-pi stacking interactions for protein building blocks to assemble into direction- and shape-anisotropic biomaterials.

-	~~Authors: Chen~~, X., ~~Zhao~~, G.	+	Shape-Anisotropic Assembly of Protein Nanocages with Identical Building Blocks by Designed Intermolecular pi-pi Interactions.,Chen X, Zhang T, Liu H, Zang J, Lv C, Du M, Zhao G Adv Sci (Weinh). 2023 Dec;10(35):e2305398. doi: 10.1002/advs.202305398. Epub 2023 , Oct 23. PMID:37870198<ref>PMID:37870198</ref>

-	~~Description: Crystal Structure~~ of ~~Human H~~-~~Ferritin variant 123F assembling in solution 1~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: Chen, X]]	+	<div class="pdbe-citations 8jai" style="background-color:#fffaf0;"></div>
-	[[Category: Zhao, G]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Chen X]]
		+	[[Category: Zhao G]]

OCA: Protected "8jai" [edit=sysop:move=sysop]

OCA — Thu, 18 May 2023 05:31:47 GMT

Protected "8jai" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:31, 18 May 2023

OCA: New page: '''Unreleased structure''' The entry 8jai is ON HOLD Authors: Chen, X., Zhao, G. Description: Crystal Structure of Human H-Ferritin variant 123F assembling in solution 1 [[Category: Un...

OCA — Thu, 18 May 2023 05:31:46 GMT

New page: '''Unreleased structure''' The entry 8jai is ON HOLD Authors: Chen, X., Zhao, G. Description: Crystal Structure of Human H-Ferritin variant 123F assembling in solution 1 [[Category: Un...

New page

'''Unreleased structure'''

The entry 8jai is ON HOLD

Authors: Chen, X., Zhao, G.

Description: Crystal Structure of Human H-Ferritin variant 123F assembling in solution 1
[[Category: Unreleased Structures]]
[[Category: Chen, X]]
[[Category: Zhao, G]]

8jai - Revision history

OCA at 11:42, 1 February 2024

OCA: Protected "8jai" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8jai is ON HOLD Authors: Chen, X., Zhao, G. Description: Crystal Structure of Human H-Ferritin variant 123F assembling in solution 1 [[Category: Un...