OCA at 08:01, 22 May 2024

OCA — Wed, 22 May 2024 08:01:57 GMT

←Older revision		Revision as of 08:01, 22 May 2024
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-	'''Unreleased structure'''

-	~~The entry~~ 8jew is ~~ON HOLD until Paper Publication~~	+	==Human sodium-dependent vitamin C transporter 1 bound to L-ascorbic acid in an inward-open state==
-		+	<StructureSection load='8jew' size='340' side='right'caption='[[8jew]], [[Resolution\|resolution]] 2.49Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8jew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JEW FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.49Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASC:ASCORBIC+ACID'>ASC</scene>, <scene name='pdbligand=AV0:Lauryl+Maltose+Neopentyl+Glycol'>AV0</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=LBN:1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine'>LBN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jew OCA], [https://pdbe.org/8jew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jew RCSB], [https://www.ebi.ac.uk/pdbsum/8jew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jew ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/S23A1_HUMAN S23A1_HUMAN] Sodium:ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (PubMed:10556483, PubMed:10556521, PubMed:10631088, PubMed:36749388). Has retained some ancestral activity toward nucleobases such as urate, an oxidized purine. Low-affinity high-capacity sodium:urate cotransporter, may regulate serum urate levels by serving as a renal urate re-absorber (PubMed:36749388).<ref>PMID:10556483</ref> <ref>PMID:10556521</ref> <ref>PMID:10631088</ref> <ref>PMID:36749388</ref> Inactive transporter.<ref>PMID:10556483</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Kobayashi TA]]
		+	[[Category: Kusakizako T]]
		+	[[Category: Nureki O]]

OCA at 04:17, 17 April 2024

OCA — Wed, 17 Apr 2024 04:17:35 GMT

←Older revision		Revision as of 04:17, 17 April 2024
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8jew is ON HOLD	+	The entry 8jew is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 04:33, 3 April 2024

OCA — Wed, 03 Apr 2024 04:33:07 GMT

←Older revision		Revision as of 04:33, 3 April 2024
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8jew is ON HOLD ~~until Paper Publication~~	+	The entry 8jew is ON HOLD

	Authors:		Authors:

OCA at 19:39, 28 June 2023

OCA — Wed, 28 Jun 2023 19:39:27 GMT

←Older revision		Revision as of 19:39, 28 June 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8jew is ON HOLD	+	The entry 8jew is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8jew" [edit=sysop:move=sysop]

OCA — Thu, 25 May 2023 02:28:31 GMT

Protected "8jew" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:28, 25 May 2023

OCA: New page: '''Unreleased structure''' The entry 8jew is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 25 May 2023 02:28:30 GMT

New page: '''Unreleased structure''' The entry 8jew is ON HOLD Authors: Description: Category: Unreleased Structures

New page