OCA at 21:21, 28 June 2023

OCA — Wed, 28 Jun 2023 21:21:22 GMT

←Older revision		Revision as of 21:21, 28 June 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8jns is ~~ON HOLD~~	+	==cryo-EM structure of a CED-4 hexamer==
-		+	<StructureSection load='8jns' size='340' side='right'caption='[[8jns]], [[Resolution\|resolution]] 4.20Å' scene=''>
-	~~Authors~~: ~~Yini~~, L., ~~Yigong~~, S.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8jns]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JNS FirstGlance]. <br>
-	~~Description~~: ~~cryo~~-~~EM structure~~ of a ~~CED~~-4 ~~hexamer~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 4.2Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Yigong, S~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jns OCA], [https://pdbe.org/8jns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jns RCSB], [https://www.ebi.ac.uk/pdbsum/8jns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jns ProSAT]</span></td></tr>
-	[[Category: ~~Yini, L~~]]	+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CED4_CAEEL CED4_CAEEL] Isoform a plays a major role in programmed cell death (PCD, apoptosis). Egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. Isoform b prevents PCD.<ref>PMID:1286611</ref> <ref>PMID:8706125</ref> <ref>PMID:9027313</ref> <ref>PMID:10688797</ref> <ref>PMID:15383288</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Caenorhabditis elegans]]
		+	[[Category: Large Structures]]
		+	[[Category: Li Y]]
		+	[[Category: Shi Y]]

OCA: Protected "8jns" [edit=sysop:move=sysop]

OCA — Wed, 14 Jun 2023 06:28:26 GMT

Protected "8jns" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:28, 14 June 2023

OCA: New page: '''Unreleased structure''' The entry 8jns is ON HOLD Authors: Yini, L., Yigong, S. Description: cryo-EM structure of a CED-4 hexamer Category: Unreleased Structures [[Category: Yig...

OCA — Wed, 14 Jun 2023 06:28:24 GMT

New page: '''Unreleased structure''' The entry 8jns is ON HOLD Authors: Yini, L., Yigong, S. Description: cryo-EM structure of a CED-4 hexamer Category: Unreleased Structures [[Category: Yig...

New page

'''Unreleased structure'''

The entry 8jns is ON HOLD

Authors: Yini, L., Yigong, S.

Description: cryo-EM structure of a CED-4 hexamer
[[Category: Unreleased Structures]]
[[Category: Yigong, S]]
[[Category: Yini, L]]

8jns - Revision history

OCA at 21:21, 28 June 2023

OCA: Protected "8jns" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8jns is ON HOLD Authors: Yini, L., Yigong, S. Description: cryo-EM structure of a CED-4 hexamer Category: Unreleased Structures [[Category: Yig...