OCA at 11:02, 3 January 2024

OCA — Wed, 03 Jan 2024 11:02:37 GMT

←Older revision		Revision as of 11:02, 3 January 2024
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8jp0 is ~~ON HOLD until Paper Publication~~	+	==structure of human sodium-calciumexchanger NCX1==
-		+	<StructureSection load='8jp0' size='340' side='right'caption='[[8jp0]], [[Resolution\|resolution]] 3.50Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8jp0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JP0 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.5Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EKY:2-{4-[(2,5-difluorophenyl)methoxy]phenoxy}-5-ethoxyaniline'>EKY</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jp0 OCA], [https://pdbe.org/8jp0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jp0 RCSB], [https://www.ebi.ac.uk/pdbsum/8jp0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jp0 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/NAC1_HUMAN NAC1_HUMAN] Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca(2+) transport during excitation-contraction coupling in muscle (PubMed:1374913, PubMed:11241183, PubMed:1476165). In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum (PubMed:1374913, PubMed:11241183, PubMed:1476165). SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline (PubMed:1374913, PubMed:11241183, PubMed:1476165). Required for normal embryonic heart development and the onset of heart contractions (By similarity).[UniProtKB:P70414]<ref>PMID:11241183</ref> <ref>PMID:1374913</ref> <ref>PMID:1476165</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Dong Y]]
		+	[[Category: Zhao Y]]

OCA at 03:49, 9 August 2023

OCA — Wed, 09 Aug 2023 03:49:11 GMT

←Older revision		Revision as of 03:49, 9 August 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8jp0 is ON HOLD	+	The entry 8jp0 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8jp0" [edit=sysop:move=sysop]

OCA — Wed, 21 Jun 2023 08:05:09 GMT

Protected "8jp0" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:05, 21 June 2023

OCA: New page: '''Unreleased structure''' The entry 8jp0 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 21 Jun 2023 08:05:08 GMT

New page: '''Unreleased structure''' The entry 8jp0 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8jp0 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

8jp0 - Revision history

OCA at 11:02, 3 January 2024

OCA at 03:49, 9 August 2023

OCA: Protected "8jp0" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8jp0 is ON HOLD Authors: Description: Category: Unreleased Structures