8qxd - Revision history

OCA at 08:04, 22 May 2024

OCA — Wed, 22 May 2024 08:04:09 GMT

←Older revision		Revision as of 08:04, 22 May 2024
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8qxd is ~~ON HOLD until Paper Publication~~	+	==Cryo-EM structure of the cross-exon pre-B complex==
-		+	<StructureSection load='8qxd' size='340' side='right'caption='[[8qxd]], [[Resolution\|resolution]] 9.60Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8qxd]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QXD FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 9.6Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qxd OCA], [https://pdbe.org/8qxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qxd RCSB], [https://www.ebi.ac.uk/pdbsum/8qxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qxd ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/PRP8_HUMAN PRP8_HUMAN] Defects in PRPF8 are the cause of retinitis pigmentosa type 13 (RP13) [MIM:[https://omim.org/entry/600059 600059]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP13 inheritance is autosomal dominant.<ref>PMID:17317632</ref> <ref>PMID:11468273</ref> [:]<ref>PMID:11910553</ref> <ref>PMID:12714658</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PRP8_HUMAN PRP8_HUMAN] Central component of the spliceosome, which may play a role in aligning the pre-mRNA 5'- and 3'-exons for ligation. Interacts with U5 snRNA, and with pre-mRNA 5'-splice sites in B spliceosomes and 3'-splice sites in C spliceosomes.
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Dybkov O]]
		+	[[Category: Kastner B]]
		+	[[Category: Kumar V]]
		+	[[Category: Ludwig S]]
		+	[[Category: Luehrmann R]]
		+	[[Category: Stark H]]
		+	[[Category: Urlaub H]]
		+	[[Category: Will CL]]
		+	[[Category: Zhang Z]]
		+	[[Category: Zhong J]]

OCA at 06:02, 14 February 2024

OCA — Wed, 14 Feb 2024 06:02:53 GMT

←Older revision		Revision as of 06:02, 14 February 2024
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8qxd is ON HOLD	+	The entry 8qxd is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 08:48, 17 January 2024

OCA — Wed, 17 Jan 2024 08:48:26 GMT

←Older revision		Revision as of 08:48, 17 January 2024
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8qxd is ON HOLD ~~until sometime in the future~~	+	The entry 8qxd is ON HOLD

	Authors:		Authors:

OCA at 08:47, 8 November 2023

OCA — Wed, 08 Nov 2023 08:47:08 GMT

←Older revision		Revision as of 08:47, 8 November 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8qxd is ON HOLD	+	The entry 8qxd is ON HOLD until sometime in the future

-	Authors: ~~Zhang, Z., Kumar, V., Dybkov, O., Will, C.L., Zhong, J., Ludwig, S., Urlaub, H., Kastner, B., Stark, H., Luehrmann, R.~~	+	Authors:

-	Description: ~~Cryo-EM structure of the cross-exon pre-B complex~~	+	Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Kastner, B]]
-	[[Category: Dybkov, O]]
-	[[Category: Luehrmann, R]]
-	[[Category: Will, C.L]]
-	[[Category: Zhang, Z]]
-	[[Category: Kumar, V]]
-	[[Category: Ludwig, S]]
-	[[Category: Zhong, J]]
-	[[Category: Stark, H]]
-	[[Category: Urlaub, H]]

OCA: Protected "8qxd" [edit=sysop:move=sysop]

OCA — Wed, 01 Nov 2023 10:39:23 GMT

Protected "8qxd" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:39, 1 November 2023

OCA: New page: '''Unreleased structure''' The entry 8qxd is ON HOLD Authors: Zhang, Z., Kumar, V., Dybkov, O., Will, C.L., Zhong, J., Ludwig, S., Urlaub, H., Kastner, B., Stark, H., Luehrmann, R. Des...

OCA — Wed, 01 Nov 2023 10:39:22 GMT

New page: '''Unreleased structure''' The entry 8qxd is ON HOLD Authors: Zhang, Z., Kumar, V., Dybkov, O., Will, C.L., Zhong, J., Ludwig, S., Urlaub, H., Kastner, B., Stark, H., Luehrmann, R. Des...

New page

'''Unreleased structure'''

The entry 8qxd is ON HOLD

Authors: Zhang, Z., Kumar, V., Dybkov, O., Will, C.L., Zhong, J., Ludwig, S., Urlaub, H., Kastner, B., Stark, H., Luehrmann, R.

Description: Cryo-EM structure of the cross-exon pre-B complex
[[Category: Unreleased Structures]]
[[Category: Kastner, B]]
[[Category: Dybkov, O]]
[[Category: Luehrmann, R]]
[[Category: Will, C.L]]
[[Category: Zhang, Z]]
[[Category: Kumar, V]]
[[Category: Ludwig, S]]
[[Category: Zhong, J]]
[[Category: Stark, H]]
[[Category: Urlaub, H]]