OCA at 08:04, 22 May 2024

OCA — Wed, 22 May 2024 08:04:14 GMT

←Older revision		Revision as of 08:04, 22 May 2024
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8qzs is ~~ON HOLD until Paper Publication~~	+	==Cryo-EM structure of the cross-exon B-like complex==
-		+	<StructureSection load='8qzs' size='340' side='right'caption='[[8qzs]], [[Resolution\|resolution]] 4.10Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8qzs]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QZS FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 4.1Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qzs OCA], [https://pdbe.org/8qzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qzs RCSB], [https://www.ebi.ac.uk/pdbsum/8qzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qzs ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/PRP8_HUMAN PRP8_HUMAN] Defects in PRPF8 are the cause of retinitis pigmentosa type 13 (RP13) [MIM:[https://omim.org/entry/600059 600059]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP13 inheritance is autosomal dominant.<ref>PMID:17317632</ref> <ref>PMID:11468273</ref> [:]<ref>PMID:11910553</ref> <ref>PMID:12714658</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PRP8_HUMAN PRP8_HUMAN] Central component of the spliceosome, which may play a role in aligning the pre-mRNA 5'- and 3'-exons for ligation. Interacts with U5 snRNA, and with pre-mRNA 5'-splice sites in B spliceosomes and 3'-splice sites in C spliceosomes.
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Dybkov O]]
		+	[[Category: Kastner B]]
		+	[[Category: Kumar V]]
		+	[[Category: Ludwig S]]
		+	[[Category: Luehrmann R]]
		+	[[Category: Stark H]]
		+	[[Category: Urlaub H]]
		+	[[Category: Will CL]]
		+	[[Category: Zhang Z]]
		+	[[Category: Zhong J]]

OCA at 06:02, 14 February 2024

OCA — Wed, 14 Feb 2024 06:02:58 GMT

←Older revision		Revision as of 06:02, 14 February 2024
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8qzs is ON HOLD	+	The entry 8qzs is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8qzs" [edit=sysop:move=sysop]

OCA — Wed, 08 Nov 2023 08:48:59 GMT

Protected "8qzs" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:48, 8 November 2023

OCA: New page: '''Unreleased structure''' The entry 8qzs is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 08 Nov 2023 08:48:57 GMT

New page: '''Unreleased structure''' The entry 8qzs is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8qzs is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

8qzs - Revision history

OCA at 08:04, 22 May 2024

OCA at 06:02, 14 February 2024

OCA: Protected "8qzs" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8qzs is ON HOLD Authors: Description: Category: Unreleased Structures