OCA at 09:43, 21 June 2023

OCA — Wed, 21 Jun 2023 09:43:12 GMT

←Older revision		Revision as of 09:43, 21 June 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8soi is ~~ON HOLD~~	+	==Structure of human ULK1 complex core (2:1:1 stoichiometry)==
-		+	<StructureSection load='8soi' size='340' side='right'caption='[[8soi]], [[Resolution\|resolution]] 4.20Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8soi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SOI FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8soi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8soi OCA], [https://pdbe.org/8soi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8soi RCSB], [https://www.ebi.ac.uk/pdbsum/8soi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8soi ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RBCC1_HUMAN RBCC1_HUMAN] Involved in autophagy (PubMed:21775823). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy (By similarity). Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis (By similarity). Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (PubMed:10769033, PubMed:12221124). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 (By similarity). Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:14533007). Plays a crucial role in muscular differentiation (PubMed:12163359). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity).[UniProtKB:Q9ESK9]<ref>PMID:10769033</ref> <ref>PMID:12095676</ref> <ref>PMID:12163359</ref> <ref>PMID:12221124</ref> <ref>PMID:14533007</ref> <ref>PMID:21775823</ref> <ref>PMID:23392225</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Chen M]]
		+	[[Category: Hurley JH]]

OCA at 06:45, 14 June 2023

OCA — Wed, 14 Jun 2023 06:45:22 GMT

←Older revision		Revision as of 06:45, 14 June 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8soi is ON HOLD ~~until Paper Publication~~	+	The entry 8soi is ON HOLD

	Authors:		Authors:

OCA at 04:26, 7 June 2023

OCA — Wed, 07 Jun 2023 04:26:15 GMT

←Older revision		Revision as of 04:26, 7 June 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8soi is ON HOLD	+	The entry 8soi is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8soi" [edit=sysop:move=sysop]

OCA — Wed, 10 May 2023 05:22:22 GMT

Protected "8soi" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:22, 10 May 2023

OCA: New page: '''Unreleased structure''' The entry 8soi is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 10 May 2023 05:22:21 GMT

New page: '''Unreleased structure''' The entry 8soi is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8soi is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

8soi - Revision history

OCA at 09:43, 21 June 2023

OCA at 06:45, 14 June 2023

OCA at 04:26, 7 June 2023

OCA: Protected "8soi" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8soi is ON HOLD Authors: Description: Category: Unreleased Structures