OCA at 12:10, 6 March 2024

OCA — Wed, 06 Mar 2024 12:10:04 GMT

←Older revision		Revision as of 12:10, 6 March 2024
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8tka is ~~ON HOLD until Paper Publication~~	+	==Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant==
-		+	<StructureSection load='8tka' size='340' side='right'caption='[[8tka]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~Authors~~: ~~Prasad~~, B.V.V., ~~Zhao~~, B., Hu, L.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8tka]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mammalian_orthoreovirus_1 Mammalian orthoreovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TKA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TKA FirstGlance]. <br>
-	~~Description~~: ~~Structure~~ of ~~Orthoreovirus~~ RNA ~~Chaperone SigmaNS R6A mutant~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	[[Category: Hu, L]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tka OCA], [https://pdbe.org/8tka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tka RCSB], [https://www.ebi.ac.uk/pdbsum/8tka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tka ProSAT]</span></td></tr>
-	[[Category: ~~Zhao, B~~]]	+	</table>
-	[[Category: ~~Prasad,~~ B~~.V.V~~]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/SIGNS_REOVD SIGNS_REOVD] Protein that binds to ssRNA and participates with protein mu-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place (PubMed:11152519). Plays a role in the inhibition of the integrated stress response (ISR) to escape from host cell translational shutoff (PubMed:28794026). Participates in the disruption of stress granules (SG) through its association with host G3BP1 and mu-NS (PubMed:28794026).<ref>PMID:11152519</ref> <ref>PMID:28794026</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Mammalian orthoreovirus 1]]
		+	[[Category: Hu L]]
		+	[[Category: Prasad BVV]]
		+	[[Category: Zhao B]]

OCA at 05:01, 27 September 2023

OCA — Wed, 27 Sep 2023 05:01:58 GMT

←Older revision		Revision as of 05:01, 27 September 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8tka is ON HOLD	+	The entry 8tka is ON HOLD until Paper Publication

	Authors: Prasad, B.V.V., Zhao, B., Hu, L.		Authors: Prasad, B.V.V., Zhao, B., Hu, L.

OCA: Protected "8tka" [edit=sysop:move=sysop]

OCA — Wed, 02 Aug 2023 09:25:05 GMT

Protected "8tka" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:25, 2 August 2023

OCA: New page: '''Unreleased structure''' The entry 8tka is ON HOLD Authors: Prasad, B.V.V., Zhao, B., Hu, L. Description: Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant [[Category: Unre...

OCA — Wed, 02 Aug 2023 09:25:04 GMT

New page: '''Unreleased structure''' The entry 8tka is ON HOLD Authors: Prasad, B.V.V., Zhao, B., Hu, L. Description: Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant [[Category: Unre...

New page

'''Unreleased structure'''

The entry 8tka is ON HOLD

Authors: Prasad, B.V.V., Zhao, B., Hu, L.

Description: Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant
[[Category: Unreleased Structures]]
[[Category: Hu, L]]
[[Category: Zhao, B]]
[[Category: Prasad, B.V.V]]

8tka - Revision history

OCA at 12:10, 6 March 2024

OCA at 05:01, 27 September 2023

OCA: Protected "8tka" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8tka is ON HOLD Authors: Prasad, B.V.V., Zhao, B., Hu, L. Description: Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant [[Category: Unre...