8u1j - Revision history

OCA: Protected "8u1j" [edit=sysop:move=sysop]

OCA — Wed, 20 Sep 2023 14:49:44 GMT

Protected "8u1j" [edit=sysop:move=sysop]

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Revision as of 14:49, 20 September 2023

OCA: New page: ==N-Terminal domain of DNA-Damage Response Protein C (DdrC) from Deinococcus radiodurans - Crystal form xMJ7102== == Structural highlights ==
<table><tr><td colspan='2'>[[8u1j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8U1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8U1J FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8u1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8u1j OCA], [https://pdbe.org/8u1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8u1j RCSB], [https://www.ebi.ac.uk/pdbsum/8u1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8u1j ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DDRC_DEIRA DDRC_DEIRA] Appears to contribute to D.radiodurans capacity to survive exposure to ionizing radiation (PubMed:15454524). Likely functions as a DNA damage-induced nucleoid-associated protein (NAP) that contributes to the enhanced level of nucleoid compaction after irradiation by bridging DNA duplexes, thereby limiting the dispersion of the fragmented genome immediately after irradiation to facilitate subsequent DNA repair. In vitro, binds both ssDNA and dsDNA, and is able to compact circular DNA, circularize linear DNA, anneal complementary DNA strands and protect DNA from nucleases (PubMed:35801857, PubMed:28542368).<ref>PMID:15454524</ref> <ref>PMID:28542368</ref> <ref>PMID:35801857</ref>
== References ==
<references/>
TOC
</StructureSection>
[[Category: Deinococcus radiodurans R1]]
[[Category: Large Structures]]
[[Category: Junop MS]]
[[Category: Song Y]]
[[Category: Szabla R]]