OCA at 08:42, 9 May 2024

OCA — Thu, 09 May 2024 08:42:18 GMT

←Older revision		Revision as of 08:42, 9 May 2024
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 9biv is ~~ON HOLD~~	+	==Crystal Structure of Ubc13 with a New Active Site Loop Conformation==
-		+	<StructureSection load='9biv' size='340' side='right'caption='[[9biv]], [[Resolution\|resolution]] 1.68Å' scene=''>
-	~~Authors~~: ~~Farraj~~, R.A., ~~Edwards~~, R.A., ~~Glover, J~~.N.M.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[9biv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BIV FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure~~ of ~~Ubc13 with~~ a ~~New Active Site Loop Conformation~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.68Å</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9biv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9biv OCA], [https://pdbe.org/9biv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9biv RCSB], [https://www.ebi.ac.uk/pdbsum/9biv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9biv ProSAT]</span></td></tr>
-	[[Category: ~~Farraj, R.A~~]]	+	</table>
-	[[Category: Edwards~~, R.A~~]]	+	== Function ==
-	[[Category: Glover~~, J.N.M~~]]	+	[https://www.uniprot.org/uniprot/UB2V2_HUMAN UB2V2_HUMAN] Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.<ref>PMID:9705497</ref> <ref>PMID:10089880</ref> <ref>PMID:14562038</ref> <ref>PMID:20061386</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Edwards RA]]
		+	[[Category: Farraj RA]]
		+	[[Category: Glover JNM]]

OCA: Protected "9biv" [edit=sysop:move=sysop]

OCA — Wed, 01 May 2024 05:18:41 GMT

Protected "9biv" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:18, 1 May 2024

OCA: New page: '''Unreleased structure''' The entry 9biv is ON HOLD Authors: Farraj, R.A., Edwards, R.A., Glover, J.N.M. Description: Crystal Structure of Ubc13 with a New Active Site Loop Conformati...

OCA — Wed, 01 May 2024 05:18:40 GMT

New page: '''Unreleased structure''' The entry 9biv is ON HOLD Authors: Farraj, R.A., Edwards, R.A., Glover, J.N.M. Description: Crystal Structure of Ubc13 with a New Active Site Loop Conformati...

New page

'''Unreleased structure'''

The entry 9biv is ON HOLD

Authors: Farraj, R.A., Edwards, R.A., Glover, J.N.M.

Description: Crystal Structure of Ubc13 with a New Active Site Loop Conformation
[[Category: Unreleased Structures]]
[[Category: Farraj, R.A]]
[[Category: Edwards, R.A]]
[[Category: Glover, J.N.M]]

9biv - Revision history

OCA at 08:42, 9 May 2024

OCA: Protected "9biv" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 9biv is ON HOLD Authors: Farraj, R.A., Edwards, R.A., Glover, J.N.M. Description: Crystal Structure of Ubc13 with a New Active Site Loop Conformati...