Acyl carrier protein synthase - Revision history

Michal Harel at 08:04, 21 May 2024

Michal Harel — Tue, 21 May 2024 08:04:27 GMT

←Older revision		Revision as of 08:04, 21 May 2024
Line 12:		Line 12:
	PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].		PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].

-	*~~Bet~~-ketoacyl-acyl carrier protein synthase II is involved in temperature controlled fatty acid synthesis<ref>PMID:6988423</ref>.	+	*'''Beta-ketoacyl-acyl carrier protein synthase II''' is involved in temperature controlled fatty acid synthesis<ref>PMID:6988423</ref>.

	See also [[Acyl carrier protein]], [[Fatty acid synthesis]].		See also [[Acyl carrier protein]], [[Fatty acid synthesis]].
Line 18:		Line 18:
	==3D structures of acyl carrier protein synthase==		==3D structures of acyl carrier protein synthase==
	[[Acyl carrier protein synthase 3D structures]]		[[Acyl carrier protein synthase 3D structures]]
-
-	== References ==
-	<references/>

	</StructureSection>		</StructureSection>

Michal Harel at 08:02, 21 May 2024

Michal Harel — Tue, 21 May 2024 08:02:15 GMT

←Older revision		Revision as of 08:02, 21 May 2024
Line 11:		Line 11:

	PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].		PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].
		+
		+	*Bet-ketoacyl-acyl carrier protein synthase II is involved in temperature controlled fatty acid synthesis<ref>PMID:6988423</ref>.

	See also [[Acyl carrier protein]], [[Fatty acid synthesis]].		See also [[Acyl carrier protein]], [[Fatty acid synthesis]].
Line 16:		Line 18:
	==3D structures of acyl carrier protein synthase==		==3D structures of acyl carrier protein synthase==
	[[Acyl carrier protein synthase 3D structures]]		[[Acyl carrier protein synthase 3D structures]]
		+
		+	== References ==
		+	<references/>

	</StructureSection>		</StructureSection>

Michal Harel at 11:00, 9 January 2023

Michal Harel — Mon, 09 Jan 2023 11:00:40 GMT

←Older revision		Revision as of 11:00, 9 January 2023
Line 12:		Line 12:
	PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].		PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].

-	See also [[Acyl carrier protein]].	+	See also [[Acyl carrier protein]], [[Fatty acid synthesis]].

	==3D structures of acyl carrier protein synthase==		==3D structures of acyl carrier protein synthase==

Alexander Berchansky at 10:03, 19 December 2019

Alexander Berchansky — Thu, 19 Dec 2019 10:03:41 GMT

←Older revision		Revision as of 10:03, 19 December 2019
Line 10:		Line 10:
	The ''B. subtilis'' AcpS trimer ([[1f80]]) <scene name='3hqj/Acp/2'>binds</scene> three molecules of the acyl carrier protein (ASP). The interactions between ''B. subtilis'' AcpS and ACP are predominantly <scene name='3hqj/Acp/3'>electrostatic</scene>. The ''B. subtilis'' AcpS (white) is shown in spacefill representation, the agrinines, lysines, and histidines are colored <font color='blue'><b>blue</b></font>, while aspartates and glutamates are colored <font color='red'><b>red</b></font>. The ACP molecule (<span style="color:lime;background-color:black;font-weight:bold;">green</span>) is shown in ribbon representation with aspartates and glutamates as sticks and colored <font color='red'><b>red</b></font>. The ''B. subtilis'' AcpS has large <scene name='3hqj/Acp/4'>electropositive interface</scene> with ASP. <scene name='3hqj/Acp/5'>Electrostatic representation</scene> of ''Mtb'' AcpS surface using the similar orientation as ''B. subtilis'' AcpS, shows a moderate electronegative nature in the putative ACP binding site near the <font color='red'><b>ASP 15</b></font>. The ''Mtb'' ASPM structure ([[1klp]], corresponding to ACP) demonstrates considerably lower negative charge. So, the electrostatic interactions between ''Mtb'' AcpS and ASPM are, probably, less important.		The ''B. subtilis'' AcpS trimer ([[1f80]]) <scene name='3hqj/Acp/2'>binds</scene> three molecules of the acyl carrier protein (ASP). The interactions between ''B. subtilis'' AcpS and ACP are predominantly <scene name='3hqj/Acp/3'>electrostatic</scene>. The ''B. subtilis'' AcpS (white) is shown in spacefill representation, the agrinines, lysines, and histidines are colored <font color='blue'><b>blue</b></font>, while aspartates and glutamates are colored <font color='red'><b>red</b></font>. The ACP molecule (<span style="color:lime;background-color:black;font-weight:bold;">green</span>) is shown in ribbon representation with aspartates and glutamates as sticks and colored <font color='red'><b>red</b></font>. The ''B. subtilis'' AcpS has large <scene name='3hqj/Acp/4'>electropositive interface</scene> with ASP. <scene name='3hqj/Acp/5'>Electrostatic representation</scene> of ''Mtb'' AcpS surface using the similar orientation as ''B. subtilis'' AcpS, shows a moderate electronegative nature in the putative ACP binding site near the <font color='red'><b>ASP 15</b></font>. The ''Mtb'' ASPM structure ([[1klp]], corresponding to ACP) demonstrates considerably lower negative charge. So, the electrostatic interactions between ''Mtb'' AcpS and ASPM are, probably, less important.

-	PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].	+	PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].
		+
		+	See also [[Acyl carrier protein]].

	==3D structures of acyl carrier protein synthase==		==3D structures of acyl carrier protein synthase==

Michal Harel at 09:31, 21 March 2019

Michal Harel — Thu, 21 Mar 2019 09:31:12 GMT

←Older revision		Revision as of 09:31, 21 March 2019
Line 17:		Line 17:
	</StructureSection>		</StructureSection>

-	==3D structures of acyl carrier protein synthase==

-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*ACPS
-
-	**[[1af8]], [[2af8]], [[2kg8]], [[2kg9]], [[2kga]], [[2kgc]], [[2kgd]], [[2kge]] – ScACPS – ''Streptomyces coelicolor'' – NMR<br />
-	**[[2jca]] - ScACPS <br />
-	**[[1fte]], [[1ftf]] - SpACPS – ''Streptococcus pneumoniae''<br />
-	**[[1f7l]], [[1f7t]] - BsACPS (mutant) – ''Bacillus subtilis''<br />
-	**[[4jm7]] - SaACPS – ''Staphylococcus aureus''<br />
-	**[[3hqj]], [[3h7q]], [[3ne1]], [[3ne3]], [[3ne9]], [[3nfd]] - MtACPS – ''Mycobacterium tuberculosis''<br />
-	**[[4hc6]] – MtACPS<br />
-	**[[3gwm]] - ACPS – ''Mycobacterium smegmatis''<br />
-	**[[3qmn]] - VcACPS – ''Vibrio cholera''<br />
-	**[[5cxd]] – ACPS – ''Staphylococcus aureus''<br />
-	**[[5vbx]] – Ec holo-ACPS - ''Escherichia coli''<br />
-
-	*ACPS complex
-
-	**[[2jbz]] - ScACPS + CoA<br />
-	**[[2wds]], [[2wdy]] - ScACPS (mutant) + CoA<br />
-	**[[2wdo]] - ScACPS + acetyl-CoA<br />
-	**[[1fth]] – SpACPS + ADP<br />
-	**[[1f80]] - BsACPS (mutant) + ACP<br />
-	**[[2qg8]] - ACPS + ADP – ''Plasmodium yoelii''<br />
-	**[[4dxe]] - SaACPS + ACP<br />
-	**[[3hyk]] - ACPS + ADP – ''Bacillus anthracis''<br />
-	**[[5vcb]] – Ec holo-ACPS + ACP <br />
-	**[[5suv]] - NmACPS + CoA – ''Nisseria meningitidis''<br />
-
-	*β-ketoacyl-ACPS
-
-	**[[1w0i]] - AtACPS – ''Arabidopsis thaliana''<br />
-	**[[2ix4]] - AtACPS + hexanoic acid<br />
-	**[[2c9h]], [[2iwy]], [[3hhd]] – hACPS – human<br />
-	**[[2iwz]] - hACPS + hexanoic acid<br />
-
-	*β-ketoacyl-ACPS I
-
-	**[[1dd8]], [[1g5x]], [[2buh]], [[2aq7]], [[2vb7]], [[2vb9]] - EcACPS I <br />
-	**[[1h4f]], [[2byw]], [[2byy]], [[2bz4]] - EcACPS I (mutant)<br />
-	**[[2wgd]] - MtACPS I <br />
-	**[[2wgf]] - MtACPS I (mutant)<br />
-	**[[2was]] - yACPS I PPT domain – yeast<br />
-	**[[3oyt]] - YpACPS I – ''Yersinia psetis''<br />
-	**[[4xox]] – VcACPS I<br />
-
-	*ACPS I complex
-
-	**[[1fj4]], [[1fj8]], [[2aqb]], [[2vb8]] - EcACPS I + antibiotic<br />
-	**[[2vba]] - EcACPS I + inhibitor<br />
-	**[[1ek4]] - EcACPS I (mutant) + dodecanoic acid<br />
-	**[[2bui]] - EcACPS I + octanoic acid<br />
-	**[[1f91]], [[2byx]], [[2byz]], [[2bz3]] - EcACPS I (mutant) + fatty acid substrate<br />
-	**[[5kof]] - EcACPS I + ACP<br />
-	**[[2wge]], [[5ld8]] - MtACPS I + antibiotic<br />
-	**[[2wgg]] - MtACPS I (mutant) + antibiotic<br />
-	**[[4c6u]], [[4c6v]], [[4c6w]], [[4c6x]], [[4c6z]], [[4c70]], [[4c71]], [[4c72]], [[4c73]] - MtACPS I + inhibitor<br />
-	**[[2wat]] - yACPS I PPT domain + CoA<br />
-
-	*β-ketoacyl-ACPS II
-
-	**[[1e5m]] - ACPS II – ''Synechocytosis''<br />
-	**[[1j3n]] - TtACPS II – ''Thermus thermophilus''<br />
-	**[[1ox0]], [[1oxh]] - SpACPS II<br />
-	**[[2alm]], [[2rjt]] - MtACPS II (mutant)<br />
-	**[[2gqd]] - SaACPS II <br />
-	**[[2gp6]] - MtACPS II <br />
-	**[[3e60]] – ACPS II – ''Bartonella henselae''<br />
-	**[[3kzu]] - ACPS II – ''Brucella melitensis''<br />
-	**[[3o04]], [[5sxo]] - ACPS II – ''Listeria monocytogenes''<br />
-	**[[4ddo]] - BvACPS II – ''Burkholderia vietnamiensis''<br />
-	**[[1kas]], [[2gfw]] – EcACPS II<br />
-	**[[2gfv]] - EcACPS II (mutant)<br />
-	**[[4b7v]] - PaACPS II – ''Pseudonomas aeruginosa''<br />
-	**[[4jb6]] - PaACPS II (mutant)<br />
-	**[[4jga]] - PaACPS II – ''Rickettsia rickettsii''<br />
-	**[[4jrh]], [[4jrm]] - VcACPS II <br />
-	**[[4ls5]] - BsACPS II <br />
-	**[[4ls6]] - BsACPS II (mutant)<br />
-	**[[4qav]], [[5cmo]] - NmACPS II <br />
-	**[[4r8e]] - YpACPS II <br />
-
-	*ACPS II complex
-
-	**[[1b3n]] - EcACPS II + antibiotic<br />
-	**[[2gfx]], [[3g0y]], [[3g11]], [[3hnz]], [[3ho2]], [[3ho9]], [[3i8p]] - EcACPS II (mutant) + antibiotic<br />
-	**[[2gfy]] - EcACPS II (mutant) + dodecanoic acid<br />
-	**[[4f32]] - BvACPS II + antibiotic<br />
-	**[[4jpf]] - PaACPS II + inhibitor<br />
-	**[[4ls7]], [[4ls8]] - BsACPS II + antibiotic<br />
-
-	*β-ketoacyl-ACPS III
-
-	**[[1hzp]], [[1m1m]] - MtACPS III <br />
-	**[[1u6e]], [[2ahb]], [[2aj9]] - MtACPS III (mutant)<br />
-	**[[1mzj]] - ACPS III – ''Streptomyces''<br />
-	**[[1zow]], [[3il7]] - SaACPS III <br />
-	**[[2ebd]] - ACPS III – ''Aquifex aeolicus''<br />
-	**[[3gwa]], [[3gwe]] - ACPS III – ''Burkholderia pseudomallei''<br />
-	**[[4dfe]], [[4efi]] - ACPS III – ''Burkholderia xenovorans''<br />
-	**[[3il3]] - HiACPS III – ''Haemophilus influenza''<br />
-	**[[3fk5]] - ACPS III – ''Xanthomonas oryzae''<br />
-	**[[3led]] - ACPS III – ''Pseudonomas palustris''<br />
-	**[[2x3e]] - PaACPS III <br />
-	**[[5dwz]] - PaACPS III (mutant)<br />
-	**[[1ebl]], [[1hn9]], [[1hnk]], [[3il9]] - EcACPS III<br />
-	**[[4ewp]] – ACPS III – ''Micrococcus luteus''<br />
-	**[[4ryb]] - NmACPS III <br />
-	**[[4wzu]] - VcACPS III-2 <br />
-	**[[4x9k]], [[4x9o]] - VcACPS III-2 (mutant)<br />
-	**[[5by7]] - ACPS III – ''Verrucosispora maris''<br />
-	**[[1ub7]] - TtACPS III (mutant)<br />
-	**[[4z19]], [[4ylt]] - YpACPS III <br />
-
-	*ACPS III complex
-
-	**[[1hnd]], [[1hnh]], [[2gyo]], [[2eft]] - EcACPS III + CoA<br />
-	**[[1hnj]] - EcACPS III + malonyl-CoA<br />
-	**[[2qx1]] - EcACPS III + decyl-CoA<br />
-	**[[1mzs]], [[5bnm]], [[5bnr]], [[5bns]] - EcACPS III + inhibitor<br />
-	**[[5bqs]] - SpACPS III + inhibitor<br />
-	**[[4z8d]] - HiACPS III + inhibitor<br />
-	**[[1u6s]] - MtACPS III (mutant) + lauroyl-CoA<br />
-	**[[2qnx]], [[2qo1]] - MtACPS III + undecanoic acid<br />
-	**[[2qo0]] - MtACPS III (mutant) + undecanoic acid<br />
-	**[[2qnz]] - MtACPS III + decyl formate<br />
-	**[[2qny]] - MtACPS III (mutant) + decyl formate<br />
-	**[[1ub7]] - TtACPS III (mutant)<br />
-	**[[3il4]] - EfACPS III + CoA – ''Enterococcus faecalis''<br />
-	**[[3il5]] - EfACPS III + benzoic acid derivative<br />
-	**[[3il6]] - EfACPS III (mutant) + benzoic acid derivative<br />
-	**[[4nhd]] - VcACPS III + CoA<br />
-	**[[4x0o]] - VcACPS III-2 + acetyl-CoA<br />
-	**[[5kp2]], [[5v0p]] - VcACPS III-2 + octanoyl-CoA<br />
-	}}
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 09:05, 21 March 2019

Michal Harel — Thu, 21 Mar 2019 09:05:59 GMT

←Older revision		Revision as of 09:05, 21 March 2019
Line 11:		Line 11:

	PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].		PPT subtypes are the ''E. coli'' '''ACPS''' and the ''B. subtilis'' '''Sfp'''. For details on Spf see [[Molecular Playground/4'-PHOSPHOPANTETHEINYL TRANSFERASE (Sfp)]].
		+
		+	==3D structures of acyl carrier protein synthase==
		+	[[Acyl carrier protein synthase 3D structures]]

	</StructureSection>		</StructureSection>

Michal Harel at 11:31, 5 March 2018

Michal Harel — Mon, 05 Mar 2018 11:31:28 GMT

←Older revision		Revision as of 11:31, 5 March 2018
Line 31:		Line 31:
	**[[3qmn]] - VcACPS – ''Vibrio cholera''<br />		**[[3qmn]] - VcACPS – ''Vibrio cholera''<br />
	**[[5cxd]] – ACPS – ''Staphylococcus aureus''<br />		**[[5cxd]] – ACPS – ''Staphylococcus aureus''<br />
		+	**[[5vbx]] – Ec holo-ACPS - ''Escherichia coli''<br />

	*ACPS complex		*ACPS complex
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	**[[2qg8]] - ACPS + ADP – ''Plasmodium yoelii''<br />		**[[2qg8]] - ACPS + ADP – ''Plasmodium yoelii''<br />
	**[[4dxe]] - SaACPS + ACP<br />		**[[4dxe]] - SaACPS + ACP<br />
-	**[[3hyk]] - ACPS + ADP – ''Bacillus anthracis''	+	**[[3hyk]] - ACPS + ADP – ''Bacillus anthracis''<br />
		+	**[[5vcb]] – Ec holo-ACPS + ACP <br />
		+	**[[5suv]] - NmACPS + CoA – ''Nisseria meningitidis''<br />

	*β-ketoacyl-ACPS		*β-ketoacyl-ACPS
Line 52:		Line 55:
	*β-ketoacyl-ACPS I		*β-ketoacyl-ACPS I

-	**[[1dd8]], [[1g5x]], [[2buh]], [[2aq7]], [[2vb7]], [[2vb9]] - EcACPS I ~~- ''Escherichia coli''~~<br />	+	**[[1dd8]], [[1g5x]], [[2buh]], [[2aq7]], [[2vb7]], [[2vb9]] - EcACPS I <br />
	**[[1h4f]], [[2byw]], [[2byy]], [[2bz4]] - EcACPS I (mutant)<br />		**[[1h4f]], [[2byw]], [[2byy]], [[2bz4]] - EcACPS I (mutant)<br />
	**[[2wgd]] - MtACPS I <br />		**[[2wgd]] - MtACPS I <br />
Line 67:		Line 70:
	**[[2bui]] - EcACPS I + octanoic acid<br />		**[[2bui]] - EcACPS I + octanoic acid<br />
	**[[1f91]], [[2byx]], [[2byz]], [[2bz3]] - EcACPS I (mutant) + fatty acid substrate<br />		**[[1f91]], [[2byx]], [[2byz]], [[2bz3]] - EcACPS I (mutant) + fatty acid substrate<br />
		+	**[[5kof]] - EcACPS I + ACP<br />
	**[[2wge]], [[5ld8]] - MtACPS I + antibiotic<br />		**[[2wge]], [[5ld8]] - MtACPS I + antibiotic<br />
	**[[2wgg]] - MtACPS I (mutant) + antibiotic<br />		**[[2wgg]] - MtACPS I (mutant) + antibiotic<br />
Line 92:		Line 96:
	**[[4ls5]] - BsACPS II <br />		**[[4ls5]] - BsACPS II <br />
	**[[4ls6]] - BsACPS II (mutant)<br />		**[[4ls6]] - BsACPS II (mutant)<br />
-	**[[4qav]], [[5cmo]] - NmACPS II ~~– ''Nisseria meningitidis''~~<br />	+	**[[4qav]], [[5cmo]] - NmACPS II <br />
	**[[4r8e]] - YpACPS II <br />		**[[4r8e]] - YpACPS II <br />

Line 146:		Line 150:
	**[[4nhd]] - VcACPS III + CoA<br />		**[[4nhd]] - VcACPS III + CoA<br />
	**[[4x0o]] - VcACPS III-2 + acetyl-CoA<br />		**[[4x0o]] - VcACPS III-2 + acetyl-CoA<br />
-	**[[5kp2]] - VcACPS III-2 + octanoyl-CoA<br />	+	**[[5kp2]], [[5v0p]] - VcACPS III-2 + octanoyl-CoA<br />
	}}		}}
	[[Category:Topic Page]]		[[Category:Topic Page]]

Joel L. Sussman at 14:22, 3 October 2017

Joel L. Sussman — Tue, 03 Oct 2017 14:22:18 GMT

←Older revision		Revision as of 14:22, 3 October 2017
Line 1:		Line 1:
-	<StructureSection load='~~3hqj~~' size='350' scene='3hqj/Trimer/1' caption="Acyl carrier protein synthase complex with CoA and Mg+2 ion (cyan) [[3hqj]]" >	+	<StructureSection load='' size='350' scene='3hqj/Trimer/1' caption="Acyl carrier protein synthase complex with CoA and Mg+2 ion (cyan) [[3hqj]]" >

	The crystal structure of '''Acyl carrier protein synthase (AcpS)''' from [http://http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis ''Mycobacterium tuberculosis''] (''Mtb'') was solved at 1.95 Å ([[3hqj]]). It crystallized as one <scene name='3hqj/Trimer/2'>monomer</scene> per asymmetric unit. Since ''Mtb'' AcpS has biologically active trimeric arrangement, <scene name='3hqj/Trimer/3'>AcpS trimer</scene> (in <span style="color:lime;background-color:black;font-weight:bold;">green</span>, <font color='blue'><b>blue</b></font>, and <scene name='3hqj/Trimer/3'>AcpS trimer</scene> (in <span style="color:orange;background-color:black;font-weight:bold;">orange</span>) was constructed using the 3-fold crystallographic symmetry in the ''P''23 space group.		The crystal structure of '''Acyl carrier protein synthase (AcpS)''' from [http://http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis ''Mycobacterium tuberculosis''] (''Mtb'') was solved at 1.95 Å ([[3hqj]]). It crystallized as one <scene name='3hqj/Trimer/2'>monomer</scene> per asymmetric unit. Since ''Mtb'' AcpS has biologically active trimeric arrangement, <scene name='3hqj/Trimer/3'>AcpS trimer</scene> (in <span style="color:lime;background-color:black;font-weight:bold;">green</span>, <font color='blue'><b>blue</b></font>, and <scene name='3hqj/Trimer/3'>AcpS trimer</scene> (in <span style="color:orange;background-color:black;font-weight:bold;">orange</span>) was constructed using the 3-fold crystallographic symmetry in the ''P''23 space group.

Michal Harel at 11:14, 20 February 2017

Michal Harel — Mon, 20 Feb 2017 11:14:47 GMT

←Older revision		Revision as of 11:14, 20 February 2017
Line 29:		Line 29:
	**[[4hc6]] – MtACPS<br />		**[[4hc6]] – MtACPS<br />
	**[[3gwm]] - ACPS – ''Mycobacterium smegmatis''<br />		**[[3gwm]] - ACPS – ''Mycobacterium smegmatis''<br />
-	**[[3qmn]] - VcACPS – ''Vibrio cholera''	+	**[[3qmn]] - VcACPS – ''Vibrio cholera''<br />
		+	**[[5cxd]] – ACPS – ''Staphylococcus aureus''<br />

	*ACPS complex		*ACPS complex
Line 56:		Line 57:
	**[[2wgf]] - MtACPS I (mutant)<br />		**[[2wgf]] - MtACPS I (mutant)<br />
	**[[2was]] - yACPS I PPT domain – yeast<br />		**[[2was]] - yACPS I PPT domain – yeast<br />
-	**[[3oyt]] - ~~ACPS~~ I – ''Yersinia psetis''<br />	+	**[[3oyt]] - YpACPS I – ''Yersinia psetis''<br />
		+	**[[4xox]] – VcACPS I<br />

	*ACPS I complex		*ACPS I complex
Line 65:		Line 67:
	**[[2bui]] - EcACPS I + octanoic acid<br />		**[[2bui]] - EcACPS I + octanoic acid<br />
	**[[1f91]], [[2byx]], [[2byz]], [[2bz3]] - EcACPS I (mutant) + fatty acid substrate<br />		**[[1f91]], [[2byx]], [[2byz]], [[2bz3]] - EcACPS I (mutant) + fatty acid substrate<br />
-	**[[2wge]] - MtACPS I + antibiotic<br />	+	**[[2wge]], [[5ld8]] - MtACPS I + antibiotic<br />
	**[[2wgg]] - MtACPS I (mutant) + antibiotic<br />		**[[2wgg]] - MtACPS I (mutant) + antibiotic<br />
	**[[4c6u]], [[4c6v]], [[4c6w]], [[4c6x]], [[4c6z]], [[4c70]], [[4c71]], [[4c72]], [[4c73]] - MtACPS I + inhibitor<br />		**[[4c6u]], [[4c6v]], [[4c6w]], [[4c6x]], [[4c6z]], [[4c70]], [[4c71]], [[4c72]], [[4c73]] - MtACPS I + inhibitor<br />
Line 80:		Line 82:
	**[[3e60]] – ACPS II – ''Bartonella henselae''<br />		**[[3e60]] – ACPS II – ''Bartonella henselae''<br />
	**[[3kzu]] - ACPS II – ''Brucella melitensis''<br />		**[[3kzu]] - ACPS II – ''Brucella melitensis''<br />
-	**[[3o04]] - ACPS II – ''Listeria monocytogenes''<br />	+	**[[3o04]], [[5sxo]] - ACPS II – ''Listeria monocytogenes''<br />
	**[[4ddo]] - BvACPS II – ''Burkholderia vietnamiensis''<br />		**[[4ddo]] - BvACPS II – ''Burkholderia vietnamiensis''<br />
	**[[1kas]], [[2gfw]] – EcACPS II<br />		**[[1kas]], [[2gfw]] – EcACPS II<br />
Line 90:		Line 92:
	**[[4ls5]] - BsACPS II <br />		**[[4ls5]] - BsACPS II <br />
	**[[4ls6]] - BsACPS II (mutant)<br />		**[[4ls6]] - BsACPS II (mutant)<br />
-	**[[4qav]] - NmACPS II – ''Nisseria meningitidis''<br />	+	**[[4qav]], [[5cmo]] - NmACPS II – ''Nisseria meningitidis''<br />
-	**[[4r8e]] - ~~ACPS~~ II ~~– ''Yersinia pestis''~~<br />	+	**[[4r8e]] - YpACPS II <br />

	*ACPS II complex		*ACPS II complex
Line 111:		Line 113:
	**[[3gwa]], [[3gwe]] - ACPS III – ''Burkholderia pseudomallei''<br />		**[[3gwa]], [[3gwe]] - ACPS III – ''Burkholderia pseudomallei''<br />
	**[[4dfe]], [[4efi]] - ACPS III – ''Burkholderia xenovorans''<br />		**[[4dfe]], [[4efi]] - ACPS III – ''Burkholderia xenovorans''<br />
-	**[[3il3]] - ~~ACPS~~ III – ''Haemophilus influenza''<br />	+	**[[3il3]] - HiACPS III – ''Haemophilus influenza''<br />
	**[[3fk5]] - ACPS III – ''Xanthomonas oryzae''<br />		**[[3fk5]] - ACPS III – ''Xanthomonas oryzae''<br />
	**[[3led]] - ACPS III – ''Pseudonomas palustris''<br />		**[[3led]] - ACPS III – ''Pseudonomas palustris''<br />
-	**[[2x3e]] - ~~ACPS~~ III <br />	+	**[[2x3e]] - PaACPS III <br />
		+	**[[5dwz]] - PaACPS III (mutant)<br />
	**[[1ebl]], [[1hn9]], [[1hnk]], [[3il9]] - EcACPS III<br />		**[[1ebl]], [[1hn9]], [[1hnk]], [[3il9]] - EcACPS III<br />
	**[[4ewp]] – ACPS III – ''Micrococcus luteus''<br />		**[[4ewp]] – ACPS III – ''Micrococcus luteus''<br />
	**[[4ryb]] - NmACPS III <br />		**[[4ryb]] - NmACPS III <br />
	**[[4wzu]] - VcACPS III-2 <br />		**[[4wzu]] - VcACPS III-2 <br />
-	**[[4x9k]] - VcACPS III-2 (mutant)<br />	+	**[[4x9k]], [[4x9o]] - VcACPS III-2 (mutant)<br />
		+	**[[5by7]] - ACPS III – ''Verrucosispora maris''<br />
		+	**[[1ub7]] - TtACPS III (mutant)<br />
		+	**[[4z19]], [[4ylt]] - YpACPS III <br />

	*ACPS III complex		*ACPS III complex
Line 126:		Line 132:
	**[[1hnj]] - EcACPS III + malonyl-CoA<br />		**[[1hnj]] - EcACPS III + malonyl-CoA<br />
	**[[2qx1]] - EcACPS III + decyl-CoA<br />		**[[2qx1]] - EcACPS III + decyl-CoA<br />
-	**[[1mzs]] - EcACPS III + inhibitor<br />	+	**[[1mzs]], [[5bnm]], [[5bnr]], [[5bns]] - EcACPS III + inhibitor<br />
		+	**[[5bqs]] - SpACPS III + inhibitor<br />
		+	**[[4z8d]] - HiACPS III + inhibitor<br />
	**[[1u6s]] - MtACPS III (mutant) + lauroyl-CoA<br />		**[[1u6s]] - MtACPS III (mutant) + lauroyl-CoA<br />
	**[[2qnx]], [[2qo1]] - MtACPS III + undecanoic acid<br />		**[[2qnx]], [[2qo1]] - MtACPS III + undecanoic acid<br />
Line 138:		Line 146:
	**[[4nhd]] - VcACPS III + CoA<br />		**[[4nhd]] - VcACPS III + CoA<br />
	**[[4x0o]] - VcACPS III-2 + acetyl-CoA<br />		**[[4x0o]] - VcACPS III-2 + acetyl-CoA<br />
-		+	**[[5kp2]] - VcACPS III-2 + octanoyl-CoA<br />
	}}		}}
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 10:56, 9 November 2016

Michal Harel — Wed, 09 Nov 2016 10:56:18 GMT

←Older revision		Revision as of 10:56, 9 November 2016
Line 25:		Line 25:
	**[[1fte]], [[1ftf]] - SpACPS – ''Streptococcus pneumoniae''<br />		**[[1fte]], [[1ftf]] - SpACPS – ''Streptococcus pneumoniae''<br />
	**[[1f7l]], [[1f7t]] - BsACPS (mutant) – ''Bacillus subtilis''<br />		**[[1f7l]], [[1f7t]] - BsACPS (mutant) – ''Bacillus subtilis''<br />
-	**~~[[3f09]],~~ [[4jm7]] - SaACPS – ''Staphylococcus aureus''<br />	+	**[[4jm7]] - SaACPS – ''Staphylococcus aureus''<br />
	**[[3hqj]], [[3h7q]], [[3ne1]], [[3ne3]], [[3ne9]], [[3nfd]] - MtACPS – ''Mycobacterium tuberculosis''<br />		**[[3hqj]], [[3h7q]], [[3ne1]], [[3ne3]], [[3ne9]], [[3nfd]] - MtACPS – ''Mycobacterium tuberculosis''<br />
	**[[4hc6]] – MtACPS<br />		**[[4hc6]] – MtACPS<br />