Arsenate reductase - Revision history

Michal Harel at 09:12, 23 February 2021

Michal Harel — Tue, 23 Feb 2021 09:12:15 GMT

←Older revision		Revision as of 09:12, 23 February 2021
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	== Function ==		== Function ==

-	'''Arsenate reductase''' (AsR) catalyzes the conversion of arsenate (As V) and glutaredoxin to arsenite (As III) and glutaredoxin disulfide.<ref>PMID:7476363</ref>	+	'''Arsenate reductase''' or '''glutaredoxin arsenate reductase''' (AsR) catalyzes the conversion of arsenate (As V) and glutaredoxin to arsenite (As III) and glutaredoxin disulfide.<ref>PMID:7476363</ref>

	== Relevance ==		== Relevance ==

Michal Harel at 08:37, 20 March 2019

Michal Harel — Wed, 20 Mar 2019 08:37:00 GMT

←Older revision		Revision as of 08:37, 20 March 2019
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	</StructureSection>		</StructureSection>

-	== 3D structures of arsenate reductase==
-
-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	* Arsenate reductase
-
-	**[[1jf8]], [[1ljl]] – SaAsR – ''Staphylococcus aureus'' <BR />
-	**[[1jfv]], [[1lk0]], [[1rxi]], [[2cd7]], [[2fxi]] – SaAsR (mutant) <BR />
-	**[[1jl3]] – BsAsR – ''Bacillus subtilis'' <BR />
-	**[[1z2d]], [[1z2e]] – BsAsR - NMR <BR />
-	**[[1i9d]] – EcAsR – ''Escherichia coli'' <BR />
-	**[[1s3c]], [[1s3d]], [[1sd8]], [[1sd9]], [[1sk2]] – EcAsR (mutant) <BR />
-	**[[2l17]], [[2l18]], [[2myn]], [[2myp]] – SyAsR – ''Synechocystis'' - NMR<BR />
-	**[[2l19]], [[2myt]], [[2myu]] – SyAsR (mutant) - NMR<BR />
-	**[[1y1l]] – AsR – ''Archaeoglobus fulgidus''<br />
-	**[[3f0i]] – AsR – ''Vibrio cholerae''<br />
-	**[[2kok]], [[2mu0]] – AsR – ''Brucella abortus''<br />
-	**[[3rh0]], [[3t38]] – AsR – ''Corynebacterium glutamicum''<br />
-
-	*Arsenate reductase complexes
-
-	**[[1jzw]] – EcAsR + arsonocysteine <BR />
-	**[[1sk1]] – EcAsR (mutant) + arsonocysteine <BR />
-	**[[1sjz]], [[1sk0]] – EcAsR (mutant) + arsonocysteine + AsO3<BR />
-	**[[1j9b]] – EcAsR + AsO3 + thiarsahydroxy-cysteine<BR />
-	**[[1lju]] – SaAsR (mutant) + arsonocysteine <BR />
-	**[[1rxe]] – SaAsR (mutant) + mercapto-nitrobenzoate <BR />
-	**[[2ipa]] – BsAsR (mutant) + thioredoxin (mutant)<BR />
-	}}
	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 08:35, 20 March 2019

Michal Harel — Wed, 20 Mar 2019 08:35:59 GMT

←Older revision		Revision as of 08:35, 20 March 2019
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	The AsR active site contains a <scene name='54/547051/Cv/5'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/6'>Entire active site</scene> (PDB entry [[1j9b]]).<ref>PMID:11709171</ref>		The AsR active site contains a <scene name='54/547051/Cv/5'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/6'>Entire active site</scene> (PDB entry [[1j9b]]).<ref>PMID:11709171</ref>
		+
		+	== 3D structures of arsenate reductase==
		+	[[Arsenate reductase 3D structures]]
		+
	</StructureSection>		</StructureSection>

Alexander Berchansky at 10:32, 7 January 2019

Alexander Berchansky — Mon, 07 Jan 2019 10:32:53 GMT

←Older revision		Revision as of 10:32, 7 January 2019
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	== Structural highlights ==		== Structural highlights ==

-	The AsR active site contains a <scene name='54/547051/Cv/4'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/3'>Entire active site</scene> (PDB entry [[1j9b]]).<ref>PMID:11709171</ref>	+	The AsR active site contains a <scene name='54/547051/Cv/5'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/6'>Entire active site</scene> (PDB entry [[1j9b]]).<ref>PMID:11709171</ref>
	</StructureSection>		</StructureSection>

Michal Harel at 10:02, 9 March 2017

Michal Harel — Thu, 09 Mar 2017 10:02:19 GMT

←Older revision		Revision as of 10:02, 9 March 2017
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	**[[1i9d]] – EcAsR – ''Escherichia coli'' <BR />		**[[1i9d]] – EcAsR – ''Escherichia coli'' <BR />
	**[[1s3c]], [[1s3d]], [[1sd8]], [[1sd9]], [[1sk2]] – EcAsR (mutant) <BR />		**[[1s3c]], [[1s3d]], [[1sd8]], [[1sd9]], [[1sk2]] – EcAsR (mutant) <BR />
-	**[[2l17]], [[2l18], [[2myn]], [[2myp]] – SyAsR – ''Synechocystis'' - NMR<BR />	+	**[[2l17]], [[2l18]], [[2myn]], [[2myp]] – SyAsR – ''Synechocystis'' - NMR<BR />
	**[[2l19]], [[2myt]], [[2myu]] – SyAsR (mutant) - NMR<BR />		**[[2l19]], [[2myt]], [[2myu]] – SyAsR (mutant) - NMR<BR />
	**[[1y1l]] – AsR – ''Archaeoglobus fulgidus''<br />		**[[1y1l]] – AsR – ''Archaeoglobus fulgidus''<br />

Michal Harel at 10:01, 9 March 2017

Michal Harel — Thu, 09 Mar 2017 10:01:45 GMT

←Older revision		Revision as of 10:01, 9 March 2017
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	**[[1i9d]] – EcAsR – ''Escherichia coli'' <BR />		**[[1i9d]] – EcAsR – ''Escherichia coli'' <BR />
	**[[1s3c]], [[1s3d]], [[1sd8]], [[1sd9]], [[1sk2]] – EcAsR (mutant) <BR />		**[[1s3c]], [[1s3d]], [[1sd8]], [[1sd9]], [[1sk2]] – EcAsR (mutant) <BR />
-	**[[2l17]], [[2l18]] – SyAsR – ''Synechocystis'' - NMR<BR />	+	**[[2l17]], [[2l18], [[2myn]], [[2myp]] – SyAsR – ''Synechocystis'' - NMR<BR />
-	**[[2l19]] – SyAsR (mutant) - NMR<BR />	+	**[[2l19]], [[2myt]], [[2myu]] – SyAsR (mutant) - NMR<BR />
	**[[1y1l]] – AsR – ''Archaeoglobus fulgidus''<br />		**[[1y1l]] – AsR – ''Archaeoglobus fulgidus''<br />
	**[[3f0i]] – AsR – ''Vibrio cholerae''<br />		**[[3f0i]] – AsR – ''Vibrio cholerae''<br />
		+	**[[2kok]], [[2mu0]] – AsR – ''Brucella abortus''<br />
	**[[3rh0]], [[3t38]] – AsR – ''Corynebacterium glutamicum''<br />		**[[3rh0]], [[3t38]] – AsR – ''Corynebacterium glutamicum''<br />

Alexander Berchansky at 13:18, 8 December 2015

Alexander Berchansky — Tue, 08 Dec 2015 13:18:25 GMT

←Older revision		Revision as of 13:18, 8 December 2015
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	</StructureSection>		</StructureSection>

-	== 3D structures of arsenate ~~reducatse~~==	+	== 3D structures of arsenate reductase==

	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

Alexander Berchansky at 13:17, 8 December 2015

Alexander Berchansky — Tue, 08 Dec 2015 13:17:57 GMT

←Older revision		Revision as of 13:17, 8 December 2015
Line 11:		Line 11:
	== Structural highlights ==		== Structural highlights ==

-	The AsR active site contains a <scene name='54/547051/Cv/4'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/3'>Entire active site</scene>.	+	The AsR active site contains a <scene name='54/547051/Cv/4'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/3'>Entire active site</scene> (PDB entry [[1j9b]]).<ref>PMID:11709171</ref>
	</StructureSection>		</StructureSection>

Michal Harel at 11:01, 3 December 2015

Michal Harel — Thu, 03 Dec 2015 11:01:45 GMT

←Older revision		Revision as of 11:01, 3 December 2015
Line 3:		Line 3:
	== Function ==		== Function ==

-	'''Arsenate reductase''' (AsR) catalyzes the conversion of arsenate (As V) and glutaredoxin to arsenite (As III) and glutaredoxin disulfide.	+	'''Arsenate reductase''' (AsR) catalyzes the conversion of arsenate (As V) and glutaredoxin to arsenite (As III) and glutaredoxin disulfide.<ref>PMID:7476363</ref>

	== Relevance ==		== Relevance ==
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	}}		}}
	== References ==		== References ==
		+	<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 07:21, 3 December 2015

Michal Harel — Thu, 03 Dec 2015 07:21:47 GMT

←Older revision		Revision as of 07:21, 3 December 2015
Line 11:		Line 11:
	== Structural highlights ==		== Structural highlights ==

-	The AsR active site contains a <scene name='54/547051/Cv/4'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/3'>~~Whole~~ active site</scene>.	+	The AsR active site contains a <scene name='54/547051/Cv/4'>catalytic Cys residue which forms a covalent thiolate-As V intermediate</scene>. <scene name='54/547051/Cv/3'>Entire active site</scene>.
	</StructureSection>		</StructureSection>

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	**[[2ipa]] – BsAsR (mutant) + thioredoxin (mutant)<BR />		**[[2ipa]] – BsAsR (mutant) + thioredoxin (mutant)<BR />
	}}		}}
		+	== References ==
	[[Category:Topic Page]]		[[Category:Topic Page]]