B-RAF with PLX4032 - Revision history

Michal Harel at 09:49, 3 January 2019

Michal Harel — Thu, 03 Jan 2019 09:49:18 GMT

←Older revision		Revision as of 09:49, 3 January 2019
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-	<applet load='3og7' size='~~800~~' color='white' frame='true' align='right' caption='BRAF' />	+	<applet load='3og7' size='400' color='white' frame='true' align='right' caption='BRAF kinase domain complex with PLX4032 (PDB code [[3og7]])' />
	<scene name='B-RAF_with_PLX4032/Plx_4032_only/2'>PLX 4032</scene><br>		<scene name='B-RAF_with_PLX4032/Plx_4032_only/2'>PLX 4032</scene><br>
	<scene name='B-RAF_with_PLX4032/Atp/2'>ATP</scene><br>		<scene name='B-RAF_with_PLX4032/Atp/2'>ATP</scene><br>

Jens Hemmingsen at 19:12, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 19:12:25 GMT

←Older revision		Revision as of 19:12, 7 October 2010
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-	<applet load='3og7' size='800' color='white' frame='true' align='right' caption='~~testcaption~~' />	+	<applet load='3og7' size='800' color='white' frame='true' align='right' caption='BRAF' />
-	<scene name='B-RAF_with_PLX4032/Plx_4032_only/2>PLX 4032</scene><br>	+	<scene name='B-RAF_with_PLX4032/Plx_4032_only/2'>PLX 4032</scene><br>
	<scene name='B-RAF_with_PLX4032/Atp/2'>ATP</scene><br>		<scene name='B-RAF_with_PLX4032/Atp/2'>ATP</scene><br>
	<scene name='B-RAF_with_PLX4032/Wild-type_b-raf/2'>Wild-Type B-RAF</scene> <br>		<scene name='B-RAF_with_PLX4032/Wild-type_b-raf/2'>Wild-Type B-RAF</scene> <br>
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	<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/5'>Superposition close up</scene> <br>		<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/5'>Superposition close up</scene> <br>
	<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/2'>Superposition active site</scene> <br>		<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/2'>Superposition active site</scene> <br>
-	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-in/1'>Confirmation Change DFG-In</scene> <br>
-	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-out/1'>Confirmation Change DFG-Out</scene>

Jens Hemmingsen at 19:06, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 19:06:31 GMT

←Older revision		Revision as of 19:06, 7 October 2010
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	<applet load='3og7' size='800' color='white' frame='true' align='right' caption='testcaption' />		<applet load='3og7' size='800' color='white' frame='true' align='right' caption='testcaption' />
-	<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>	+	<scene name='B-RAF_with_PLX4032/Plx_4032_only/2>PLX 4032</scene><br>
-	<scene name='B-RAF_with_PLX4032/Atp/1'>ATP</scene><br>	+	<scene name='B-RAF_with_PLX4032/Atp/2'>ATP</scene><br>
-	<scene name='B-RAF_with_PLX4032/Wild-type_b-raf/1'>Wild-Type B-RAF</scene> <br>	+	<scene name='B-RAF_with_PLX4032/Wild-type_b-raf/2'>Wild-Type B-RAF</scene> <br>
-	<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation~~</scene> <br>~~	+	<scene name='B-RAF_with_PLX4032/Mutated_v600e/2'>V600E Mutation</scene> <br>
-	~~<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N~~</scene> <br>	+
	<scene name='B-RAF_with_PLX4032/H-bond/4'>H-Bond Interaction Asp594 and PLX4032</scene><br>		<scene name='B-RAF_with_PLX4032/H-bond/4'>H-Bond Interaction Asp594 and PLX4032</scene><br>
-	<scene name='B-RAF_with_PLX4032/~~Dfg_in_conformation~~/1'>~~DFG in~~</scene><br>	+	<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/4'>Superposition overview</scene> <br>
-	<scene name='B-RAF_with_PLX4032/~~Phe_595_dfg_out~~/1'>~~DFG out~~</scene><br>	+	<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/5'>Superposition close up</scene> <br>
-	<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene> <br>	+	<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/2'>Superposition active site</scene> <br>
	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-in/1'>Confirmation Change DFG-In</scene> <br>		<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-in/1'>Confirmation Change DFG-In</scene> <br>
	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-out/1'>Confirmation Change DFG-Out</scene>		<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-out/1'>Confirmation Change DFG-Out</scene>

Jens Hemmingsen at 18:16, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 18:16:16 GMT

←Older revision		Revision as of 18:16, 7 October 2010
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	<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>		<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>
	<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>		<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>
-	<scene name='B-RAF_with_PLX4032/H-bond/3'>H-Bond Interaction Asp594 and PLX4032</scene><br>	+	<scene name='B-RAF_with_PLX4032/H-bond/4'>H-Bond Interaction Asp594 and PLX4032</scene><br>
	<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>		<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>
	<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>		<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>

Jens Hemmingsen at 18:14, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 18:14:42 GMT

←Older revision		Revision as of 18:14, 7 October 2010
Line 4:		Line 4:


-	<applet load='3og7' size='~~700~~' color='white' frame='true' align='right' caption='testcaption' />	+	<applet load='3og7' size='800' color='white' frame='true' align='right' caption='testcaption' />
	<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>		<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>
	<scene name='B-RAF_with_PLX4032/Atp/1'>ATP</scene><br>		<scene name='B-RAF_with_PLX4032/Atp/1'>ATP</scene><br>

Jens Hemmingsen at 18:14, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 18:14:19 GMT

←Older revision		Revision as of 18:14, 7 October 2010
Line 4:		Line 4:


		+	<applet load='3og7' size='700' color='white' frame='true' align='right' caption='testcaption' />
	<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>		<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>
	<scene name='B-RAF_with_PLX4032/Atp/1'>ATP</scene><br>		<scene name='B-RAF_with_PLX4032/Atp/1'>ATP</scene><br>
Line 15:		Line 16:
	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-in/1'>Confirmation Change DFG-In</scene> <br>		<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-in/1'>Confirmation Change DFG-In</scene> <br>
	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-out/1'>Confirmation Change DFG-Out</scene>		<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-out/1'>Confirmation Change DFG-Out</scene>
-	<applet load='3og7' size='700' color='white' frame='true' align='center' caption='testcaption' />

Jens Hemmingsen at 18:13, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 18:13:11 GMT

←Older revision		Revision as of 18:13, 7 October 2010
Line 9:		Line 9:
	<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>		<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>
	<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>		<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>
-	<scene name='B-RAF_with_PLX4032/H-bond/2'>H-Bond Interaction Asp594 and PLX4032</scene><br>	+	<scene name='B-RAF_with_PLX4032/H-bond/3'>H-Bond Interaction Asp594 and PLX4032</scene><br>
	<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>		<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>
	<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>		<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>

Jens Hemmingsen at 17:55, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 17:55:54 GMT

←Older revision		Revision as of 17:55, 7 October 2010
Line 9:		Line 9:
	<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>		<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>
	<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>		<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>
-	<scene name='B-RAF_with_PLX4032/H-bond/1'>H-Bond Interaction Asp594 and PLX4032</scene>	+	<scene name='B-RAF_with_PLX4032/H-bond/2'>H-Bond Interaction Asp594 and PLX4032</scene><br>
-	~~<script>connect(atomno=1127)(atomno=4025)HBOND</script~~> <br>	+
	<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>		<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>
	<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>		<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>

Jens Hemmingsen at 17:32, 7 October 2010

Jens Hemmingsen — Thu, 07 Oct 2010 17:32:25 GMT

←Older revision		Revision as of 17:32, 7 October 2010
Line 9:		Line 9:
	<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>		<scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br>
	<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>		<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br>
-	<scene name='B-RAF_with_PLX4032/H-bond/1'>H-Bond Interaction Asp594 and PLX4032</scene> <br>	+	<scene name='B-RAF_with_PLX4032/H-bond/1'>H-Bond Interaction Asp594 and PLX4032</scene>
		+	<script>connect(atomno=1127)(atomno=4025)HBOND</script> <br>
	<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>		<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>
	<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>		<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>

J.D. Woodruff at 13:08, 6 October 2010

J.D. Woodruff — Wed, 06 Oct 2010 13:08:09 GMT

←Older revision		Revision as of 13:08, 6 October 2010
Line 13:		Line 13:
	<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>		<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>
	<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene> <br>		<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene> <br>
-	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-in/1'>Confirmation Change DFG-In</scene>	+	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-in/1'>Confirmation Change DFG-In</scene> <br>
		+	<scene name='B-RAF_with_PLX4032/Confirmation_change_dfg-out/1'>Confirmation Change DFG-Out</scene>
	<applet load='3og7' size='700' color='white' frame='true' align='center' caption='testcaption' />		<applet load='3og7' size='700' color='white' frame='true' align='center' caption='testcaption' />