Bedaquiline - Revision history

Michal Harel at 11:36, 21 January 2024

Michal Harel — Sun, 21 Jan 2024 11:36:34 GMT

←Older revision		Revision as of 11:36, 21 January 2024
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-	<StructureSection load='' size='340' side='right' caption='~~Caption for this structure~~' scene='10/1022077/Cv/1'>	+	<StructureSection load='' size='340' side='right' caption='Bedaquiline' scene='10/1022077/Cv/1'>
	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].		Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].

Alexander Berchansky at 12:55, 2 January 2024

Alexander Berchansky — Tue, 02 Jan 2024 12:55:22 GMT

←Older revision		Revision as of 12:55, 2 January 2024
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	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].		Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].

-	Bedaquiline works by blocking the ability of M. tuberculosis to make adenosine 5'-triphosphate (ATP).<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Bedaquiline blocks the proton pump for ATP synthase of mycobacteria.<ref name="a21">PMID:25203970</ref> It is the first member of a new class of drugs called the diarylquinolines.<ref name="a21">PMID:25203970</ref> Bedaquiline is bactericidal.<ref name="a21">PMID:25203970</ref> ATP production is required for cellular energy production and its loss leads inhibition of mycobacterial growth within hours of the addition of bedaquiline.<ref name="a22">PMID:24569628</ref> The onset of bedaquiline-induced mycobacterial cell death does not occur until several days after treatment, but nonetheless kills consistently thereafter.<ref name="a22">PMID:24569628</ref>	+	Bedaquiline works by blocking the ability of M. tuberculosis to make adenosine 5'-triphosphate (ATP).<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Bedaquiline blocks the proton pump for [[ATP synthase]] of mycobacteria.<ref name="a21">PMID:25203970</ref> It is the first member of a new class of drugs called the diarylquinolines.<ref name="a21">PMID:25203970</ref> Bedaquiline is bactericidal.<ref name="a21">PMID:25203970</ref> ATP production is required for cellular energy production and its loss leads inhibition of mycobacterial growth within hours of the addition of bedaquiline.<ref name="a22">PMID:24569628</ref> The onset of bedaquiline-induced mycobacterial cell death does not occur until several days after treatment, but nonetheless kills consistently thereafter.<ref name="a22">PMID:24569628</ref>

	<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).		<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).

Alexander Berchansky at 12:51, 2 January 2024

Alexander Berchansky — Tue, 02 Jan 2024 12:51:24 GMT

←Older revision		Revision as of 12:51, 2 January 2024
Line 2:		Line 2:
	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].		Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].

-	Bedaquiline works by blocking the ability of M. tuberculosis to make adenosine 5'-triphosphate (ATP).<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref>	+	Bedaquiline works by blocking the ability of M. tuberculosis to make adenosine 5'-triphosphate (ATP).<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Bedaquiline blocks the proton pump for ATP synthase of mycobacteria.<ref name="a21">PMID:25203970</ref> It is the first member of a new class of drugs called the diarylquinolines.<ref name="a21">PMID:25203970</ref> Bedaquiline is bactericidal.<ref name="a21">PMID:25203970</ref> ATP production is required for cellular energy production and its loss leads inhibition of mycobacterial growth within hours of the addition of bedaquiline.<ref name="a22">PMID:24569628</ref> The onset of bedaquiline-induced mycobacterial cell death does not occur until several days after treatment, but nonetheless kills consistently thereafter.<ref name="a22">PMID:24569628</ref>
-		+

	<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).		<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).

Alexander Berchansky at 12:47, 2 January 2024

Alexander Berchansky — Tue, 02 Jan 2024 12:47:26 GMT

←Older revision		Revision as of 12:47, 2 January 2024
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	<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='10/1022077/Cv/1'>		<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='10/1022077/Cv/1'>
	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].		Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].
		+
		+	Bedaquiline works by blocking the ability of M. tuberculosis to make adenosine 5'-triphosphate (ATP).<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref>
		+

	<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).		<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).

Alexander Berchansky at 12:41, 2 January 2024

Alexander Berchansky — Tue, 02 Jan 2024 12:41:54 GMT

←Older revision		Revision as of 12:41, 2 January 2024
Line 3:		Line 3:

	<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).		<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).
		+
		+	<scene name='10/1022077/Cv/3'>Bedaquiline binding site</scene>.

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 12:32, 2 January 2024

Alexander Berchansky — Tue, 02 Jan 2024 12:32:16 GMT

←Older revision		Revision as of 12:32, 2 January 2024
Line 2:		Line 2:
	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].		Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].

-	<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> [[4v1f]].	+	<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> ([[4v1f]]).

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 13:47, 1 January 2024

Alexander Berchansky — Mon, 01 Jan 2024 13:47:44 GMT

←Older revision		Revision as of 13:47, 1 January 2024
Line 2:		Line 2:
	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].		Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].

-	[[4v1f]].	+	<scene name='10/1022077/Cv/2'>Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline</scene> [[4v1f]].

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 13:13, 28 December 2023

Alexander Berchansky — Thu, 28 Dec 2023 13:13:08 GMT

←Older revision		Revision as of 13:13, 28 December 2023
Line 1:		Line 1:
-	<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene=''>	+	<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='10/1022077/Cv/1'>
	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].		Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].

Alexander Berchansky at 12:38, 28 December 2023

Alexander Berchansky — Thu, 28 Dec 2023 12:38:25 GMT

←Older revision		Revision as of 12:38, 28 December 2023
Line 1:		Line 1:
	<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene=''>		<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene=''>
-	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline].	+	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline] and [[Treatment of Tuberculosis]].

	[[4v1f]].		[[4v1f]].

Alexander Berchansky at 12:34, 28 December 2023

Alexander Berchansky — Thu, 28 Dec 2023 12:34:38 GMT

←Older revision		Revision as of 12:34, 28 December 2023
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	<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene=''>		<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene=''>
-	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:~~10903938~~</ref>~~[1][5][6~~ See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline].	+	Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref> Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis.<ref name="a1">[https://www.drugs.com/monograph/bedaquiline.html "Bedaquiline Fumarate".] The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.</ref><ref name="a5">[https://web.archive.org/web/20180820052256/http://www.who.int/tb/publications/2018/rapid_communications_MDR/en/ "WHO Rapid Communication: Key changes to treatment of multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB)".] WHO. Archived from the original on 20 August 2018. Retrieved 24 April 2019.</ref><ref name="a6">PMID:30215381</ref> See also [https://en.wikipedia.org/wiki/Bedaquiline Bedaquiline].

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