Catabolite control protein - Revision history

Michal Harel at 10:34, 28 April 2019

Michal Harel — Sun, 28 Apr 2019 10:34:32 GMT

←Older revision		Revision as of 10:34, 28 April 2019
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	</StructureSection>		</StructureSection>

-	==3D structures of catabolite control protein==
-
-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*CcpA
-
-	**[[2jcg]], [[2hsg]] - BmCcpA – ''Bacillus megaterium'' <br />
-	**[[2o20]] - CcpA (mutant) – ''Streptococcus lactis'' <br />
-
-	*CcpA binary complex
-
-	**[[2oen]] - BmCcpA + phosphocarrier protein HPr <br />
-	**[[2fep]] - BsCcpA + phosphocarrier protein HPr – ''Bacillus subtilis''<br />
-	**[[4rk6]] - WpCcpA + glucose – ''Weissella paramesenteroides'' <br />
-	**[[4rk7]] - WpCcpA + sucrose <br />
-
-	*CcpA ternary complex
-
-	**[[1rzr]] – BmCcpA + phosphocarrier protein HPr + DNA <br />
-	**[[2nzu]] - BmCcpA + phosphocarrier protein HPr + glucose-6-phosphate <br />
-	**[[2nzv]] - BmCcpA + phosphocarrier protein HPr + fructose-1,6-diphosphate <br />
-	**[[1zvv]] – BsCcpA + catabolite repression Crh + DNA <br />
-	**[[3oqm]], [[3oqn]], [[3oqo]] - BsCcpA + phosphocarrier protein HPr + DNA<br />
-
-	*CcpC
-
-	**[[5z72]] - CcpC + citrate – ''Bacillus velezensis''<br />
-	}}
	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 10:33, 28 April 2019

Michal Harel — Sun, 28 Apr 2019 10:33:22 GMT

←Older revision		Revision as of 10:33, 28 April 2019
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	== Function ==		== Function ==

-	'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref>	+	'''Catabolite control protein''' (CcpA) or '''glucose-resistant amylase regulator''' is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref>

	== Structural highlights ==		== Structural highlights ==

	CcpA phosphorylation activity is carried out by a <scene name='57/570565/Cv/2'>phosphorylated Ser residue</scene> (PDB entry [[2fep]]).<ref>PMID:8195089</ref> <ref>PMID:8596444</ref>		CcpA phosphorylation activity is carried out by a <scene name='57/570565/Cv/2'>phosphorylated Ser residue</scene> (PDB entry [[2fep]]).<ref>PMID:8195089</ref> <ref>PMID:8596444</ref>
		+
		+	==3D structures of catabolite control protein==
		+	[[Catabolite control protein 3D structures]]
		+
	</StructureSection>		</StructureSection>

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	**[[2oen]] - BmCcpA + phosphocarrier protein HPr <br />		**[[2oen]] - BmCcpA + phosphocarrier protein HPr <br />
	**[[2fep]] - BsCcpA + phosphocarrier protein HPr – ''Bacillus subtilis''<br />		**[[2fep]] - BsCcpA + phosphocarrier protein HPr – ''Bacillus subtilis''<br />
		+	**[[4rk6]] - WpCcpA + glucose – ''Weissella paramesenteroides'' <br />
		+	**[[4rk7]] - WpCcpA + sucrose <br />

	*CcpA ternary complex		*CcpA ternary complex
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	**[[1zvv]] – BsCcpA + catabolite repression Crh + DNA <br />		**[[1zvv]] – BsCcpA + catabolite repression Crh + DNA <br />
	**[[3oqm]], [[3oqn]], [[3oqo]] - BsCcpA + phosphocarrier protein HPr + DNA<br />		**[[3oqm]], [[3oqn]], [[3oqo]] - BsCcpA + phosphocarrier protein HPr + DNA<br />
		+
		+	*CcpC
		+
		+	**[[5z72]] - CcpC + citrate – ''Bacillus velezensis''<br />
	}}		}}
	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 08:54, 6 December 2015

Michal Harel — Sun, 06 Dec 2015 08:54:34 GMT

←Older revision		Revision as of 08:54, 6 December 2015
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-	<StructureSection load='2fep' size='~~450~~' side='right' caption='Structure of catabolite control protein (blue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>	+	<StructureSection load='2fep' size='350' side='right' caption='Structure of catabolite control protein (blue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>
	== Function ==		== Function ==

Michal Harel at 11:48, 26 November 2015

Michal Harel — Thu, 26 Nov 2015 11:48:14 GMT

←Older revision		Revision as of 11:48, 26 November 2015
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-	<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (~~deepskyblue~~) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>	+	<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (blue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>
	== Function ==		== Function ==

Alexander Berchansky at 12:14, 23 November 2015

Alexander Berchansky — Mon, 23 Nov 2015 12:14:20 GMT

←Older revision		Revision as of 12:14, 23 November 2015
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	== Structural highlights ==		== Structural highlights ==

-	CcpA phosphorylation activity is carried out by a <scene name='57/570565/Cv/2'>phosphorylated Ser residue</scene> (PDB entry [[2fep]]).	+	CcpA phosphorylation activity is carried out by a <scene name='57/570565/Cv/2'>phosphorylated Ser residue</scene> (PDB entry [[2fep]]).<ref>PMID:8195089</ref> <ref>PMID:8596444</ref>
	</StructureSection>		</StructureSection>

Alexander Berchansky at 12:13, 23 November 2015

Alexander Berchansky — Mon, 23 Nov 2015 12:13:01 GMT

←Older revision		Revision as of 12:13, 23 November 2015
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	== Structural highlights ==		== Structural highlights ==

-	CcpA phosphorylation activity is carried out by a phosphorylated Ser residue.	+	CcpA phosphorylation activity is carried out by a <scene name='57/570565/Cv/2'>phosphorylated Ser residue</scene> (PDB entry [[2fep]]).
	</StructureSection>		</StructureSection>

Michal Harel at 10:29, 23 November 2015

Michal Harel — Mon, 23 Nov 2015 10:29:47 GMT

←Older revision		Revision as of 10:29, 23 November 2015
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	<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (deepskyblue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>		<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (deepskyblue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>
		+	== Function ==

	'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref>		'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref>
		+
		+	== Structural highlights ==
		+
		+	CcpA phosphorylation activity is carried out by a phosphorylated Ser residue.
	</StructureSection>		</StructureSection>

Alexander Berchansky at 12:15, 22 November 2015

Alexander Berchansky — Sun, 22 Nov 2015 12:15:52 GMT

←Older revision		Revision as of 12:15, 22 November 2015
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	<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (deepskyblue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>		<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (deepskyblue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>

-	'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.	+	'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref>
	</StructureSection>		</StructureSection>

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	**[[3oqm]], [[3oqn]], [[3oqo]] - BsCcpA + phosphocarrier protein HPr + DNA<br />		**[[3oqm]], [[3oqn]], [[3oqo]] - BsCcpA + phosphocarrier protein HPr + DNA<br />
	}}		}}
		+	== References ==
		+	<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Alexander Berchansky at 12:12, 22 November 2015

Alexander Berchansky — Sun, 22 Nov 2015 12:12:41 GMT

←Older revision		Revision as of 12:12, 22 November 2015
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-	<StructureSection load='2fep' size='~~350~~' side='right' caption='Structure of catabolite control protein (~~grey~~) complex with Hpr (~~khaki~~) and sulfate (PDB entry [[2fep]])' scene=''>	+	<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (deepskyblue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'>

	'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.		'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.

Michal Harel at 13:12, 19 November 2014

Michal Harel — Wed, 19 Nov 2014 13:12:12 GMT

←Older revision		Revision as of 13:12, 19 November 2014
Line 2:		Line 2:

	'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.		'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.
		+	</StructureSection>

	==3D structures of catabolite control protein==		==3D structures of catabolite control protein==