Colicin E4 - Revision history

Gemma McGoldrick: /* Killing Activities */

Gemma McGoldrick — Fri, 25 Mar 2011 12:10:55 GMT

Killing Activities

←Older revision		Revision as of 12:10, 25 March 2011
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	==Killing Activities==		==Killing Activities==

-	ColE4 kills the target cell with its [[16s ~~rRNAse~~ activity]] where it enzymatically degrades its 16s rRNA subunit, and inhibits protein synthesis in the cell. This ultimately leads to the death of the cell.	+	ColE4 kills the target cell with its [[16s rRNase activity]] where it enzymatically degrades its 16s rRNA subunit, and inhibits protein synthesis in the cell. This ultimately leads to the death of the cell.

Gemma McGoldrick: /* Killing Activities */

Gemma McGoldrick — Fri, 25 Mar 2011 12:10:11 GMT

Killing Activities

←Older revision		Revision as of 12:10, 25 March 2011
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	==Killing Activities==		==Killing Activities==

-	ColE4 kills the target cell by enzymatically ~~degrading~~ its 16s rRNA subunit, ~~thereby inhibiting~~ protein synthesis in the cell. This ultimately leads to the death of the cell.	+	ColE4 kills the target cell with its [[16s rRNAse activity]] where it enzymatically degrades its 16s rRNA subunit, and inhibits protein synthesis in the cell. This ultimately leads to the death of the cell.

Gemma McGoldrick: /* Killing Activities */

Gemma McGoldrick — Fri, 25 Feb 2011 16:51:57 GMT

Killing Activities

←Older revision		Revision as of 16:51, 25 February 2011
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	==Killing Activities==		==Killing Activities==
		+
		+	ColE4 kills the target cell by enzymatically degrading its 16s rRNA subunit, thereby inhibiting protein synthesis in the cell. This ultimately leads to the death of the cell.

Gemma McGoldrick at 16:49, 25 February 2011

Gemma McGoldrick — Fri, 25 Feb 2011 16:49:29 GMT

←Older revision		Revision as of 16:49, 25 February 2011
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-	Colicin E4 is a type of [[Colicin]], a bacteriocin made by ''E. coli which acts against other nearby ''E. coli'' to kill them with its [[16s rRNase activity]]; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.	+	Colicin E4 is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them with its [[16s rRNase activity]]; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.

	==Synthesis and release==		==Synthesis and release==

Gemma McGoldrick: /* Mechanism of uptake */

Gemma McGoldrick — Fri, 25 Feb 2011 16:49:11 GMT

Mechanism of uptake

←Older revision		Revision as of 16:49, 25 February 2011
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	==Mechanism of uptake==		==Mechanism of uptake==
		+
		+	Colicin E4 binds first to the vitamin B12 [[BtuB]] outer membrane receptor on the target cell, via its receptor binding domain. Binding to this receptor triggers the immunity protein to release from the cytotoxic domain, so that when the colicin crosses the membrane it can kill the cell. Once bound to the BtuB receptor, ColE4 uses [[OmpF]] and the TolQRAB complex to cross the membrane, using a mechanism as yet unidentified.

	==Killing Activities==		==Killing Activities==

Gemma McGoldrick: /* Synthesis and release */

Gemma McGoldrick — Fri, 25 Feb 2011 16:46:59 GMT

Synthesis and release

←Older revision		Revision as of 16:46, 25 February 2011
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	==Synthesis and release==		==Synthesis and release==

-		+	The colicin E4 operon is encoded on a plasmid in ''E. coli'', alongside a regulatory protein, and its [[Colicin Immunity Protein]], [[Im4]].

	==Mechanism of uptake==		==Mechanism of uptake==

	==Killing Activities==		==Killing Activities==

Gemma McGoldrick at 16:46, 25 February 2011

Gemma McGoldrick — Fri, 25 Feb 2011 16:46:09 GMT

←Older revision		Revision as of 16:46, 25 February 2011
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-	Colicin E4 is a type of [[Colicin]], a bacteriocin made by "E. ~~Coli"~~ which acts against other nearby "E. ~~Coli"~~ to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.	+	Colicin E4 is a type of [[Colicin]], a bacteriocin made by ''E. coli which acts against other nearby ''E. coli'' to kill them with its [[16s rRNase activity]]; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.

	==Synthesis and release==		==Synthesis and release==
		+
		+

	==Mechanism of uptake==		==Mechanism of uptake==

	==Killing Activities==		==Killing Activities==

Gemma McGoldrick: New page: Colicin E4 is a type of Colicin, a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them with its 16s rRNase activity; it digests the 16s ribosomal subun...

Gemma McGoldrick — Sat, 04 Dec 2010 11:12:19 GMT

New page: Colicin E4 is a type of Colicin, a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them with its 16s rRNase activity; it digests the 16s ribosomal subun...

New page

Colicin E4 is a type of [[Colicin]], a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.

==Synthesis and release==

==Mechanism of uptake==

==Killing Activities==