Colicin E6 - Revision history

Gemma McGoldrick: /* Killing Activities */

Gemma McGoldrick — Sat, 26 Feb 2011 14:29:51 GMT

Killing Activities

←Older revision		Revision as of 14:29, 26 February 2011
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	==Killing Activities==		==Killing Activities==
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		+	ColE6 kills its target cell with its [[16s rRNase activity]], found on its C terminus. This enzymatically degrades the 16s rRNA subunit, preventing the cell from synthesising any proteins, and ultimately killing the cell.

Gemma McGoldrick at 14:20, 26 February 2011

Gemma McGoldrick — Sat, 26 Feb 2011 14:20:08 GMT

←Older revision		Revision as of 14:20, 26 February 2011
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	==Mechanism of uptake==		==Mechanism of uptake==

-		+	The receptor binding domain of ColE6 binds to [[BtuB]], which triggers the dissociation of the immunity protein, so the cytotoxic domain can act when the colicin enters the cell. Once bound to BtuB, the complex recruits OmpF, and the TolQRAB complex, to transport the colicin across the membrane, using a mechanism not yet identified.

	==Killing Activities==		==Killing Activities==

Gemma McGoldrick at 14:13, 26 February 2011

Gemma McGoldrick — Sat, 26 Feb 2011 14:13:01 GMT

←Older revision		Revision as of 14:13, 26 February 2011
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-	Colicin E6 is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.	+	Colicin E6 is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them with its [[16s rRNase activity]]; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.
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	==Synthesis and release==		==Synthesis and release==
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		+	The ColE6 operon is encoded on a plasmid in the ''E. coli'' cell, and includes the [[Colicin Immunity Protein]], [[ImmE6]]. Once the colicin has been produced, it binds to its immunity protein; this protects the colicinogenic cell from the cytotoxic activity of the colicin.

	==Mechanism of uptake==		==Mechanism of uptake==
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	==Killing Activities==		==Killing Activities==

Gemma McGoldrick at 15:38, 9 February 2011

Gemma McGoldrick — Wed, 09 Feb 2011 15:38:49 GMT

←Older revision		Revision as of 15:38, 9 February 2011
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-	Colicin E6 is a type of [[Colicin]], a bacteriocin made by "E. ~~Coli"~~ which acts against other nearby "E. ~~Coli"~~ to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.	+	Colicin E6 is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.
	==Synthesis and release==		==Synthesis and release==

Gemma McGoldrick: New page: Colicin E6 is a type of Colicin, a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them with its 16s rRNase activity; it digests the 16s ribosomal subun...

Gemma McGoldrick — Sat, 04 Dec 2010 15:16:38 GMT

New page: Colicin E6 is a type of Colicin, a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them with its 16s rRNase activity; it digests the 16s ribosomal subun...

New page

Colicin E6 is a type of [[Colicin]], a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.
==Synthesis and release==

==Mechanism of uptake==

==Killing Activities==