Colicin U - Revision history

Gemma McGoldrick: /* Killing Activities */

Gemma McGoldrick — Fri, 25 Mar 2011 18:31:19 GMT

Killing Activities

←Older revision		Revision as of 18:31, 25 March 2011
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	==Killing Activities==		==Killing Activities==
		+
		+	Colicin U kills its target cell by [[Pore Formation]]; it inserts into the membrane of the cell and forms a pore. This leads to depolarisation of the membrane, which prevents the synthesis of ATP, ultimately leading to the death of the cell.

Gemma McGoldrick: /* Synthesis and release */

Gemma McGoldrick — Fri, 25 Mar 2011 15:09:26 GMT

Synthesis and release

←Older revision		Revision as of 15:09, 25 March 2011
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	==Synthesis and release==		==Synthesis and release==

-	The operon encoding Colicin U is encoded on a plasmid, in the cytoplasm of the ''E. coli''. The operon also encodes its [[Colicin Immunity Protein]], [[Cui]], and a protein that enables the release of the colicin from the producing cell.	+	The operon encoding Colicin U is encoded on a plasmid, in the cytoplasm of the ''E. coli''. The operon also encodes its [[Colicin Immunity Protein]], [[Cui]], and a protein that enables the release of the colicin from the producing cell.
		+
		+	The immunity protein inserts into the membrane of the colicin-producing cell to prevent the colicin from inserting into the membrane, and therefore protecting the cell from the colicin's killing activities.

	==Mechanism of uptake==		==Mechanism of uptake==

Gemma McGoldrick: /* Mechanism of uptake */

Gemma McGoldrick — Fri, 25 Mar 2011 15:08:47 GMT

Mechanism of uptake

←Older revision		Revision as of 15:08, 25 March 2011
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	==Mechanism of uptake==		==Mechanism of uptake==
		+
		+	The receptor binding domain of the colicin binds to an outer membrane receptor, as yet unidentified. The translocation domain then recruits proteins from the [[Tol]] system to translocate the colicin across the membrane. This mechanism is also so far unidentified.

	==Killing Activities==		==Killing Activities==

Gemma McGoldrick at 14:59, 25 March 2011

Gemma McGoldrick — Fri, 25 Mar 2011 14:59:29 GMT

←Older revision		Revision as of 14:59, 25 March 2011
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	==Synthesis and release==		==Synthesis and release==
		+
		+	The operon encoding Colicin U is encoded on a plasmid, in the cytoplasm of the ''E. coli''. The operon also encodes its [[Colicin Immunity Protein]], [[Cui]], and a protein that enables the release of the colicin from the producing cell.

	==Mechanism of uptake==		==Mechanism of uptake==

	==Killing Activities==		==Killing Activities==

Gemma McGoldrick at 14:44, 25 March 2011

Gemma McGoldrick — Fri, 25 Mar 2011 14:44:19 GMT

←Older revision		Revision as of 14:44, 25 March 2011
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-	Colicin U is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them ~~by forming a pore in the membrane~~, leading to depolarisation of the membrane which kills the cell.	+	Colicin U is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them through [[Pore Formation]], leading to depolarisation of the membrane which kills the cell.

	==Synthesis and release==		==Synthesis and release==

Gemma McGoldrick at 13:38, 25 February 2011

Gemma McGoldrick — Fri, 25 Feb 2011 13:38:58 GMT

←Older revision		Revision as of 13:38, 25 February 2011
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-	Colicin U is a type of [[Colicin]], a bacteriocin made by "E. ~~Coli"~~ which acts against other nearby "E. ~~Coli"~~ to kill them by forming a pore in the membrane, leading to depolarisation of the membrane which kills the cell.	+	Colicin U is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them by forming a pore in the membrane, leading to depolarisation of the membrane which kills the cell.

	==Synthesis and release==		==Synthesis and release==

Gemma McGoldrick: New page: Colicin U is a type of Colicin, a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them by forming a pore in the membrane, leading to depolarisation of t...

Gemma McGoldrick — Sat, 04 Dec 2010 17:01:50 GMT

New page: Colicin U is a type of Colicin, a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them by forming a pore in the membrane, leading to depolarisation of t...

New page

Colicin U is a type of [[Colicin]], a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them by forming a pore in the membrane, leading to depolarisation of the membrane which kills the cell.

==Synthesis and release==

==Mechanism of uptake==

==Killing Activities==