DTDP-glucose 4,6-dehydratase - Revision history

Michal Harel at 09:04, 7 February 2023

Michal Harel — Tue, 07 Feb 2023 09:04:30 GMT

←Older revision		Revision as of 09:04, 7 February 2023
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	[[5u4q]] – RmlB + NAD – ''Klebsiella pneumoniae'' <br />		[[5u4q]] – RmlB + NAD – ''Klebsiella pneumoniae'' <br />
	[[6bwl]] – RmlB + NAD + UDP – ''Bacillus thuringiensis'' <br />		[[6bwl]] – RmlB + NAD + UDP – ''Bacillus thuringiensis'' <br />
		+	[[8du1]] – RmlB + NAD – ''Elizabethkingia anophelis'' <br />

Alexander Berchansky — Sun, 10 Mar 2019 10:47:01 GMT

←Older revision		Revision as of 10:47, 10 March 2019
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	== Structural highlights ==		== Structural highlights ==
	The RmlB structure is divided into 2 domains. The N-terminal NAD-binding domain which contains the Rossmann fold and the C-terminal sugar nucleotide binding domain<ref>PMID:11796113</ref>.		The RmlB structure is divided into 2 domains. The N-terminal NAD-binding domain which contains the Rossmann fold and the C-terminal sugar nucleotide binding domain<ref>PMID:11796113</ref>.
-	*<scene name='74/748855/Cv/2'>NAD binding site</scene>.	+	*<scene name='74/748855/Cv/5'>NAD binding site</scene>.
-	*<scene name='74/748855/Cv/3'>TDB-glucose binding site</scene>.	+	*<scene name='74/748855/Cv/6'>TDB-glucose binding site</scene>.
-	*<scene name='74/748855/Cv/4'>Whole active site</scene>.	+	*<scene name='74/748855/Cv/7'>Whole active site</scene>.

	</StructureSection>		</StructureSection>

Michal Harel — Wed, 09 May 2018 08:39:42 GMT

←Older revision		Revision as of 08:39, 9 May 2018
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	[[6bwl]] – RmlB + NAD + UDP – ''Bacillus thuringiensis'' <br />		[[6bwl]] – RmlB + NAD + UDP – ''Bacillus thuringiensis'' <br />

-	~~</StructureSection>~~	+
	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel — Wed, 09 May 2018 08:39:02 GMT

←Older revision		Revision as of 08:39, 9 May 2018
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	[[6bi4]] – RmlB + NAD + TDP-sucrose – ''Bacillus anthracis''<br />		[[6bi4]] – RmlB + NAD + TDP-sucrose – ''Bacillus anthracis''<br />
	[[5u4q]] – RmlB + NAD – ''Klebsiella pneumoniae'' <br />		[[5u4q]] – RmlB + NAD – ''Klebsiella pneumoniae'' <br />
-		+	[[6bwl]] – RmlB + NAD + UDP – ''Bacillus thuringiensis'' <br />

	</StructureSection>		</StructureSection>

Joel L. Sussman — Thu, 28 Dec 2017 20:22:13 GMT

←Older revision		Revision as of 20:22, 28 December 2017
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	[[1bxk]] – EcRmlB + NAD – ''Escherichia coli'' <br />		[[1bxk]] – EcRmlB + NAD – ''Escherichia coli'' <br />
	[[1r66]], [[1r6d]] – RmlB + NAD + TDP derivative – ''Streptococcus venezuelae''<br />		[[1r66]], [[1r6d]] – RmlB + NAD + TDP derivative – ''Streptococcus venezuelae''<br />
-	[[~~4egb~~]] – RmlB + NAD + TDP-sucrose – ''Bacillus anthracis''<br />	+	[[6bi4]] – RmlB + NAD + TDP-sucrose – ''Bacillus anthracis''<br />
	[[5u4q]] – RmlB + NAD – ''Klebsiella pneumoniae'' <br />		[[5u4q]] – RmlB + NAD – ''Klebsiella pneumoniae'' <br />

Joel L. Sussman — Fri, 20 Oct 2017 10:22:21 GMT

←Older revision		Revision as of 10:22, 20 October 2017
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-	<StructureSection load='~~1ker~~' size='350' side='right' caption='RmlB dimer complex with NAD, TDP-D-glucose and sulfate (PDB code [[1ker]])' scene='74/748855/Cv/1'>	+	<StructureSection load='' size='350' side='right' caption='RmlB dimer complex with NAD, TDP-D-glucose and sulfate (PDB code [[1ker]])' scene='74/748855/Cv/1'>

	== Function ==		== Function ==

Michal Harel — Thu, 19 Oct 2017 17:50:22 GMT

←Older revision		Revision as of 17:50, 19 October 2017
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-	<StructureSection load='1ker' size='~~440~~' side='right' caption='RmlB dimer complex with NAD, TDP-D-glucose and sulfate (PDB code [[1ker]])' scene='74/748855/Cv/1'>	+	<StructureSection load='1ker' size='350' side='right' caption='RmlB dimer complex with NAD, TDP-D-glucose and sulfate (PDB code [[1ker]])' scene='74/748855/Cv/1'>

	== Function ==		== Function ==
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	== References ==		== References ==
	<references/>		<references/>
		+	[[Category:Topic Page]]

Michal Harel — Thu, 27 Apr 2017 06:56:58 GMT

←Older revision		Revision as of 06:56, 27 April 2017
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	== Function ==		== Function ==
	'''dTDP-glucose 4,6-dehydratase''' (RmlB) catalyzes the reversible conversion of dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose.		'''dTDP-glucose 4,6-dehydratase''' (RmlB) catalyzes the reversible conversion of dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose.
-	RmlB is the second of four enzymes involved in the dTDP-L-rhamnose pathway<ref>PMID:10666612</ref>. RmlB is involved in the pathway LSP O-antigen biosynthesis which is part of the bacterial outer membrane biogenesis<ref>PMID:~~11742749~~</ref>.	+	RmlB is the second of four enzymes involved in the dTDP-L-rhamnose pathway<ref>PMID:10666612</ref>. RmlB is involved in the pathway LSP O-antigen biosynthesis which is part of the bacterial outer membrane biogenesis<ref>PMID:19019146</ref>.

	== Structural highlights ==		== Structural highlights ==

Michal Harel — Thu, 27 Apr 2017 06:53:06 GMT

←Older revision		Revision as of 06:53, 27 April 2017
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	== Function ==		== Function ==
	'''dTDP-glucose 4,6-dehydratase''' (RmlB) catalyzes the reversible conversion of dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose.		'''dTDP-glucose 4,6-dehydratase''' (RmlB) catalyzes the reversible conversion of dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose.
-	RmlB is the second of four enzymes involved in the dTDP-L-rhamnose pathway<ref>PMID:10666612</ref>. RmlB is involved in the pathway LSP O-antigen biosynthesis which is part of the bacterial outer membrane biogenesis<ref>PMID:~~22833313~~</ref>.	+	RmlB is the second of four enzymes involved in the dTDP-L-rhamnose pathway<ref>PMID:10666612</ref>. RmlB is involved in the pathway LSP O-antigen biosynthesis which is part of the bacterial outer membrane biogenesis<ref>PMID:11742749</ref>.

	== Structural highlights ==		== Structural highlights ==

Michal Harel — Thu, 27 Apr 2017 06:50:38 GMT

←Older revision		Revision as of 06:50, 27 April 2017
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	== Function ==		== Function ==
	'''dTDP-glucose 4,6-dehydratase''' (RmlB) catalyzes the reversible conversion of dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose.		'''dTDP-glucose 4,6-dehydratase''' (RmlB) catalyzes the reversible conversion of dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose.
-	RmlB is the second of four enzymes involved in the dTDP-L-rhamnose pathway<ref>PMID:10666612</ref>. RmlB is involved in the pathway LSP O-antigen biosynthesis which is part of the bacterial outer membrane biogenesis<ref>PMID:~~10666612~~</ref>.	+	RmlB is the second of four enzymes involved in the dTDP-L-rhamnose pathway<ref>PMID:10666612</ref>. RmlB is involved in the pathway LSP O-antigen biosynthesis which is part of the bacterial outer membrane biogenesis<ref>PMID:22833313</ref>.

	== Structural highlights ==		== Structural highlights ==