Dihydropteroate synthase 3D structures - Revision history

Michal Harel at 09:53, 24 January 2023

Michal Harel — Tue, 24 Jan 2023 09:53:40 GMT

←Older revision		Revision as of 09:53, 24 January 2023
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	**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br />		**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br />
	**[[7l6p]] - DHPS + imidazole – ''Stenotrophomonas maltophilia''<br />		**[[7l6p]] - DHPS + imidazole – ''Stenotrophomonas maltophilia''<br />
		+	**[[8d5g]], [[8d5h]] - ubDHPS + pterin derivative – uncultured bacteria<br />

	*DHPS ternary complexes		*DHPS ternary complexes
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	**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br />		**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br />
	**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br />		**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br />
		+	**[[8d5i]] - ubDHPS + pterin derivative + PPi<br />

	*7,8-dihydro-6-hydroxymethylpterin pyrophsphokinase-DHPS		*7,8-dihydro-6-hydroxymethylpterin pyrophsphokinase-DHPS
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	**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br />		**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br />
	**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />		**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />
-	**[[6jwr]], [[6jws]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum''<br />	+	**[[4pzv]] – FtHPPK-DHPS + inhibitor<br />
		+	**[[6jwr]], [[6jws]], [[6jwu]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum''<br />
	**[[6jws]], [[6jwt]], [[6jwv]], [[6jww]], [[6jwy]], [[6jwz]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative<br />		**[[6jws]], [[6jwt]], [[6jwv]], [[6jww]], [[6jwy]], [[6jwz]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative<br />
	**[[6jwq]] – PfHPPK-DHPS + AMP + ATP<br />		**[[6jwq]] – PfHPPK-DHPS + AMP + ATP<br />

Joel L. Sussman at 05:52, 2 July 2021

Joel L. Sussman — Fri, 02 Jul 2021 05:52:30 GMT

←Older revision		Revision as of 05:52, 2 July 2021
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	**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />		**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />
	**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />		**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />
-	**~~[[5uur]],~~ [[6day]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br />	+	**[[6day]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br />
	**[[6ofw]] - XaDHPS + dihydro-pteroate<br />		**[[6ofw]] - XaDHPS + dihydro-pteroate<br />
	**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />		**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />

Michal Harel at 09:02, 29 June 2021

Michal Harel — Tue, 29 Jun 2021 09:02:04 GMT

←Older revision		Revision as of 09:02, 29 June 2021
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	*DHPS binary complexes		*DHPS binary complexes
-

	**[[1ad4]] – SaDHPS + pterin-pyrophosphate<br />		**[[1ad4]] – SaDHPS + pterin-pyrophosphate<br />
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	**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />		**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />
	**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />		**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />
-	**[[6day]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br />	+	**[[5uur]], [[6day]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br />
	**[[6ofw]] - XaDHPS + dihydro-pteroate<br />		**[[6ofw]] - XaDHPS + dihydro-pteroate<br />
	**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />		**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />
	**[[6pz2]] - DHPS + pteroic acid – ''Clostridioides difficile''<br />		**[[6pz2]] - DHPS + pteroic acid – ''Clostridioides difficile''<br />
	**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br />		**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br />
		+	**[[7l6p]] - DHPS + imidazole – ''Stenotrophomonas maltophilia''<br />

	*DHPS ternary complexes		*DHPS ternary complexes
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	**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br />		**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br />

-	*~~Bifunctional 6-hydroxymethyl-~~7,8-~~dihydropterin~~ pyrophsphokinase-DHPS	+	*7,8-dihydro-6-hydroxymethylpterin pyrophsphokinase-DHPS

		+	**[[2bmb]] - HPPK-DHPS + pterin-methyl-phosphate – yeast<br />
	**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br />		**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br />
	**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />		**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />
-	**[[~~2bmb~~]] - ~~PPPK~~-DHPS + ~~pterin~~-~~methyl~~-~~phosphate~~ - ~~yeast~~	+	**[[6jwr]], [[6jws]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum''<br />
		+	**[[6jws]], [[6jwt]], [[6jwv]], [[6jww]], [[6jwy]], [[6jwz]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative<br />
		+	**[[6jwq]] – PfHPPK-DHPS + AMP + ATP<br />
		+	**[[6kck]] – PfHPPK-DHPS + AMP + hydroxybenzoate <br />
		+	**[[6kcl]], [[6kcm]] – PfHPPK-DHPS (mutant) + AMP + hydroxybenzoate <br />

	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Joel L. Sussman at 07:26, 23 July 2020

Joel L. Sussman — Thu, 23 Jul 2020 07:26:29 GMT

←Older revision		Revision as of 07:26, 23 July 2020
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	**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />		**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />
	**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />		**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />
-	**[[6day~~]], [[5uur~~]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br />	+	**[[6day]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br />
	**[[6ofw]] - XaDHPS + dihydro-pteroate<br />		**[[6ofw]] - XaDHPS + dihydro-pteroate<br />
	**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />		**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />

Michal Harel at 07:05, 15 July 2020

Michal Harel — Wed, 15 Jul 2020 07:05:32 GMT

←Older revision		Revision as of 07:05, 15 July 2020
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	*DHPS binary complexes		*DHPS binary complexes
		+

	**[[1ad4]] – SaDHPS + pterin-pyrophosphate<br />		**[[1ad4]] – SaDHPS + pterin-pyrophosphate<br />
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	**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />		**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br />
	**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />		**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br />
-	**[[6day]] - ~~DHPS~~ + PABA – ''Xanthomonas albilineans''<br />	+	**[[6day]], [[5uur]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br />
		+	**[[6ofw]] - XaDHPS + dihydro-pteroate<br />
	**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />		**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br />
		+	**[[6pz2]] - DHPS + pteroic acid – ''Clostridioides difficile''<br />
		+	**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br />

	*DHPS ternary complexes		*DHPS ternary complexes
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	**[[3tyz]] - YpDHPS + pyrophosphate + PABA + amino-hydroxymethyl-dihydro-pteridinone<br />		**[[3tyz]] - YpDHPS + pyrophosphate + PABA + amino-hydroxymethyl-dihydro-pteridinone<br />
	**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br />		**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br />
		+	**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br />

	*Bifunctional 6-hydroxymethyl-7,8-dihydropterin pyrophsphokinase-DHPS		*Bifunctional 6-hydroxymethyl-7,8-dihydropterin pyrophsphokinase-DHPS
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	**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />		**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />
	**[[2bmb]] - PPPK-DHPS + pterin-methyl-phosphate - yeast		**[[2bmb]] - PPPK-DHPS + pterin-methyl-phosphate - yeast
		+
	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel: New page: ==3D structures of dihydropteroate synthase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *DHPS **1ad1, [[...

Michal Harel — Mon, 10 Jun 2019 09:14:04 GMT

New page: ==3D structures of dihydropteroate synthase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *DHPS **1ad1, [[...

New page

==3D structures of dihydropteroate synthase==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*DHPS

**[[1ad1]], [[4hb7]] – SaDHPS - ''Staphylococcus aureus'' 
**[[6clu]], [[6clv]] - SaDHPS (mutant) 
**[[1ajz]] – EcDHPS – ''Escherichia coli'' 
**[[1tws]], [[3v5o]] – BaDHPS – ''Bacillus anthracis'' 
**[[2dqw]] - TtDHPS – ''Thermus thermophilus'' 
**[[2vef]] - SpDHPS – ''Streptococcus pneumoniae'' 
**[[2vp8]] – MtDHPS – ''Mycobacterium tuberculosis'' 
**[[2y5j]] – BcDHPS – ''Burkholderia cenocepacia'' 
**[[3tzn]] – YpDHPS – ''Yersinia pestis'' 
**[[4o0q]] – DhDHPS – ''Desulfitobacterium hafniense'' 
**[[5umg]] - DHPS – ''Klebsiella pneumoniae'' 
**[[5usw]] - DHPS – ''Vibrio fischeri'' 
**[[5vis]] - DHPS – soil metagenome 

*DHPS binary complexes

**[[1ad4]] – SaDHPS + pterin-pyrophosphate 
**[[1aj2]] – EcDHPS + dihydro-pterin-methanyl-phosphonophosphate 
**[[5u0v]] - EcDHPS + nitrosoisocytosine inhibitor 
**[[5u0w]], [[5u0y]], [[5u0z]], [[5u11]], [[5u12]], [[5u13]], [[5u14]], [[5v79]], [[5v7a]] - EcDHPS + guanine inhibitor 
**[[5u10]] - EcDHPS + pteroic acid inhibitor 
**[[1eye]] - MtDHPS + pterin-methyl-phosphate 
**[[1tww]] - BaDHPS + hydroxymethylpterin-diphosphate 
**[[1twz]] - BaDHPS + pterin-methyl-phosphate 
**[[1tx0]] - BaDHPS + pteroic acid 
**[[1tx2]], [[3h21]], [[3h22]], [[3h23]], [[3h24]], [[3h26]], [[3h2a]], [[3h2c]], [[3h2e]], [[3h2f]], [[3h2m]], [[3h2n]], [[3h2o]], [[4d8z]], [[4d9p]], [[4dai]], [[4db7]], [[4d8a]], [[4daf]], [[4nhv]], [[4nil]], [[4nir]], [[4nl1]] - BaDHPS + inhibitor 
**[[2dza]] - TtDHPS + PABA 
**[[2dzb]] - TtDHPS + hydroxymethylpterin-diphosphate 
**[[2veg]] - SpDHPS + pterin-methyl-phosphate 
**[[2y5s]] - BcDHPS + dihydro-pteroate 
**[[3tya]] - BaDHPS + dihydro-pteroate 
**[[3tyc]] - BaDHPS + amino-hydroxymethyl-dihydro-pteridinone 
**[[3tr9]] - DHPS + pteroic acid – ''Coxiella burnetii'' 
**[[3tyu]] – YpDHPS + pteroic acid 
**[[5jq9]] - YpDHPS + sulfonamide inhibitor 
**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative 
**[[6day]] - DHPS + PABA – ''Xanthomonas albilineans'' 
**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis'' 

*DHPS ternary complexes

**[[1aj0]] – EcDHPS + sulfanilamide + amino-methyldiene-dihydro-pteridinone 
**[[3tyb]] - BaDHPS + hydroxybenzoic acid + amino-hydroxymethyl-dihydro-pteridinone 
**[[3tyd]] - BaDHPS + pyrophosphate+ amino-hydroxymethyl-dihydro-pteridinone 
**[[3tye]] - BaDHPS + sulfa derivative + amino-hydroxymethyl-dihydro-pteridinone 
**[[3tyz]] - YpDHPS + pyrophosphate + PABA + amino-hydroxymethyl-dihydro-pteridinone 
**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate 

*Bifunctional 6-hydroxymethyl-7,8-dihydropterin pyrophsphokinase-DHPS

**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis'' 
**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate 
**[[2bmb]] - PPPK-DHPS + pterin-methyl-phosphate - yeast
}}

[[Category:Topic Page]]