Eric Comeau/ sandbox - Revision history

Karsten Theis at 20:05, 11 January 2018

Karsten Theis — Thu, 11 Jan 2018 20:05:18 GMT

←Older revision		Revision as of 20:05, 11 January 2018
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	<scene name='61/611454/Hemoglobin/7'>Two hemoglobin proteins with mutated Beta protein</scene>		<scene name='61/611454/Hemoglobin/7'>Two hemoglobin proteins with mutated Beta protein</scene>
		+
		+	The <scene name='61/611454/Hemoglobin/9'>hydrophobic patch</scene> is shown in gray, the mutations to valine in blue.

	<scene name='61/611454/Hemoglobin/8'>Hemoglobin and Valine</scene>		<scene name='61/611454/Hemoglobin/8'>Hemoglobin and Valine</scene>

Karsten Theis — Thu, 11 Jan 2018 19:56:48 GMT

←Older revision		Revision as of 19:56, 11 January 2018
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	== Physical model ==		== Physical model ==
-	The 3D-printed models are of the tetramer, with one beta subunit valine marked with a blue rod. One hydrophobic surface patch is marked with a hole. In the browser, the <scene name='61/611454/One_with_val/1'>tetramer</scene> is shown in red (alpha subunits) and orangered (beta subunits), with both valines shown in blue. In a second scene, <scene name='61/611454/Two_with_val/1'>two interacting tetramers</scene> are shown. You can see that one of the four valines is buried in the contact area ~~betweeen~~ the two tetramers.	+	The 3D-printed models are of the tetramer, with one beta subunit valine marked with a blue rod. One hydrophobic surface patch is marked with a hole. In the browser, the <scene name='61/611454/One_with_val/1'>tetramer</scene> is shown in red (alpha subunits) and orangered (beta subunits), with both valines shown in blue. In a second scene, <scene name='61/611454/Two_with_val/1'>two interacting tetramers</scene> are shown. You can see that one of the four valines is buried in the contact area between the two tetramers. The <scene name='61/611454/Val_and_patch/2'>hydrophobic patch</scene> (shown in gray) consists of Phe 85 and Leu 88 side chains in an indentation of the protein's surface.

	== Sickle Cell Anemia ==		== Sickle Cell Anemia ==

Karsten Theis — Thu, 11 Jan 2018 19:29:49 GMT

←Older revision		Revision as of 19:29, 11 January 2018
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	You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.		You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.

-	== ~~Function~~ ==	+	== Physical model ==
		+	The 3D-printed models are of the tetramer, with one beta subunit valine marked with a blue rod. One hydrophobic surface patch is marked with a hole. In the browser, the <scene name='61/611454/One_with_val/1'>tetramer</scene> is shown in red (alpha subunits) and orangered (beta subunits), with both valines shown in blue. In a second scene, <scene name='61/611454/Two_with_val/1'>two interacting tetramers</scene> are shown. You can see that one of the four valines is buried in the contact area betweeen the two tetramers.

	== Sickle Cell Anemia ==		== Sickle Cell Anemia ==

Eric Comeau — Mon, 08 Dec 2014 20:11:53 GMT

←Older revision		Revision as of 20:11, 8 December 2014
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	<scene name='61/611454/Hemoglobin/7'>Two hemoglobin proteins with mutated Beta protein</scene>		<scene name='61/611454/Hemoglobin/7'>Two hemoglobin proteins with mutated Beta protein</scene>

-	<scene name='61/611454/Hemoglobin/6'>Hemoglobin and Valine</scene>	+	<scene name='61/611454/Hemoglobin/8'>Hemoglobin and Valine</scene>

	<scene		<scene

Eric Comeau — Mon, 08 Dec 2014 20:10:04 GMT

←Older revision		Revision as of 20:10, 8 December 2014
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	== Sickle Cell Anemia ==		== Sickle Cell Anemia ==

-	<scene name='61/611454/Hemoglobin/5'>Two hemoglobin proteins with mutated Beta protein</scene>	+	<scene name='61/611454/Hemoglobin/7'>Two hemoglobin proteins with mutated Beta protein</scene>

	<scene name='61/611454/Hemoglobin/6'>Hemoglobin and Valine</scene>		<scene name='61/611454/Hemoglobin/6'>Hemoglobin and Valine</scene>

Eric Comeau — Mon, 08 Dec 2014 20:05:31 GMT

←Older revision		Revision as of 20:05, 8 December 2014
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	<scene name='61/611454/Hemoglobin/5'>Two hemoglobin proteins with mutated Beta protein</scene>		<scene name='61/611454/Hemoglobin/5'>Two hemoglobin proteins with mutated Beta protein</scene>
		+
	<scene name='61/611454/Hemoglobin/6'>Hemoglobin and Valine</scene>		<scene name='61/611454/Hemoglobin/6'>Hemoglobin and Valine</scene>

Eric Comeau — Mon, 08 Dec 2014 20:05:07 GMT

←Older revision		Revision as of 20:05, 8 December 2014
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	<scene name='61/611454/Hemoglobin/5'>Two hemoglobin proteins with mutated Beta protein</scene>		<scene name='61/611454/Hemoglobin/5'>Two hemoglobin proteins with mutated Beta protein</scene>
-		+	<scene name='61/611454/Hemoglobin/6'>Hemoglobin and Valine</scene>

	<scene		<scene

Eric Comeau — Mon, 08 Dec 2014 20:00:05 GMT

←Older revision		Revision as of 20:00, 8 December 2014
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	== Sickle Cell Hemoglobin ==		== Sickle Cell Hemoglobin ==
-	<StructureSection load='~~1stp~~' size='340' side='right' caption='Caption for this structure' scene=''>	+	<StructureSection load='2hbs' size='340' side='right' caption='Caption for this structure' scene=''>
	This is a default text for your page '''Eric Comeau/ sandbox'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs.		This is a default text for your page '''Eric Comeau/ sandbox'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs.
	You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.		You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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	== Sickle Cell Anemia ==		== Sickle Cell Anemia ==

-	<scene name='61/611454/Hemoglobin/4'>Two hemoglobin proteins with mutated Beta protein</scene>	+	<scene name='61/611454/Hemoglobin/5'>Two hemoglobin proteins with mutated Beta protein</scene>

Eric Comeau — Mon, 08 Dec 2014 19:53:54 GMT

←Older revision		Revision as of 19:53, 8 December 2014
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	== Sickle Cell Anemia ==		== Sickle Cell Anemia ==

-	<scene name='61/611454/Hemoglobin/3'>Two ~~hemoglobins~~ with mutated ~~residues in all-atom~~</scene>	+	<scene name='61/611454/Hemoglobin/4'>Two hemoglobin proteins with mutated Beta protein</scene>

Eric Comeau — Mon, 08 Dec 2014 19:49:13 GMT

←Older revision		Revision as of 19:49, 8 December 2014
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	== Sickle Cell Anemia ==		== Sickle Cell Anemia ==
		+
		+	<scene name='61/611454/Hemoglobin/3'>Two hemoglobins with mutated residues in all-atom</scene>
		+
		+
	<scene		<scene
	name='61/611454/Hemoglobin/2'>Full Protein</scene>		name='61/611454/Hemoglobin/2'>Full Protein</scene>