Fatty acid-binding protein - Revision history

Michal Harel at 10:06, 26 June 2019

Michal Harel — Wed, 26 Jun 2019 10:06:09 GMT

←Older revision		Revision as of 10:06, 26 June 2019
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	</StructureSection>		</StructureSection>

-	==3D structures of fatty acid-binding protein==
-
-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*Intestinal fatty acid-binding protein
-
-	**[[1kzw]], [[3ifb]] - hIFABP – human – NMR<BR />
-	**[[1kzx]] - hIFABP (mutant) – NMR<BR />
-	**[[1ael]], [[1a57]], [[1sa8]] - rIFABP – rat – NMR<BR />
-	**[[1t8v]] - rIFABP (mutant) – NMR<BR />
-	**[[1ifb]], [[1ifc]] - rIFABP <br />
-	**[[1dc9]] - rIFABP (mutant)<br />
-
-	*''Intestinal fatty acid-binding protein binary complex''
-
-	**[[3akm]], [[2mo5]] - hIFABP + fatty acid analog<br />
-	**[[2mji]] - hIFABP + ketorolac - NMR<br />
-	**[[3akn]], [[1icm]], [[1icn]], [[2ifb]] - rIFABP + fatty acid analog<br />
-	**[[1ure]] - rIFABP + palmitate – NMR<BR />
-
-	*Epidermal fatty acid-binding protein
-
-	**[[1b56]], [[1jjj]], [[4lkp]] - hEFABP <br />
-	**[[4azr]], [[4lkt]] - hEFABP + fatty acid<br />
-	**[[4azm]], [[5ur9]], [[5hz5]] - hEFABP + inhibitor<br />
-	**[[4azn]], [[4azo]] - mEFABP <br />
-	**[[4azp]], [[4azq]] - mEFABP + fatty acid<br />
-
-	*Heart-type fatty acid-binding protein
-
-	**[[1g5w]] - hHFABP – NMR<BR />
-	**[[3rsw]], [[5ce4]], [[6aq1]] – hHFABP<br />
-	**[[3wbg]] – hHFABP + sulfonate derivative<br />
-	**[[5hz9]] – hHFABP + inhibitor<br />
-	**[[3wvm]], [[4tjz]], [[4tkb]], [[4tkh]], [[4tkj]], [[4wbk]], [[3wxq]] - hHFABP + fatty acid<br />
-	**[[5b29]], [[5b28]], [[5b27]] - hHFABP (mutant) + fatty acid<br />
-	**[[1bwy]] – HFABP – bovine<br />
-	**[[5d8j]] – HFABP + Fab – mouse<br />
-
-	*Brain-type fatty acid-binding protein
-
-	**[[1fdq]], [[1jjx]] - hBFABP<br />
-	**[[1fe3]] - hBFABP + oleate<br />
-	**[[5ura]] - hBFABP + inhibitor <br />
-
-	*Liver-type fatty acid-binding protein
-
-	**[[2f73]], [[3stn]], [[3b2h]], [[3b2i]], [[3b2j]], [[3b2k]], [[3b2l]], [[3vg2]], [[3vg3]], [[3vg4]], [[3vg5]], [[3vg6]], [[3vg7]] - hLFABP<br />
-	**[[2py1]], [[2l67]], [[2l68]] - hLFABP – NMR<BR />
-	**[[1tvq]], [[1mvg]] - cLFABP – chicken<br />
-	**[[1zry]] - cLFABP - NMR<BR />
-	**[[2ju3]], [[2ju7]] - rLFABP – NMR<BR />
-	**[[1p6p]] - LFABP – toad<br />
-	**[[2ft9]] – AmLFABP - ''Ambystoma mexicanum''
-
-	*''Liver-type fatty acid-binding protein binary complex''
-
-	**[[3stk]], [[3stm]] - hLFABP + palmitate<br />
-	**[[2lkk]] - hLFABP + oleate – NMR<br />
-	**[[2ju8]] - rLFABP + oleate – NMR<BR />
-	**[[1lfo]] - rLFABP + oleate<br />
-	**[[1tw4]], [[2jn3]], [[2lfo]] - cLFABP + cholate<br />
-	**[[2jn3]] - cLFABP + chenodeoxycholate<br />
-	**[[2k62]] - cLFABP + bile acid-based Gd chelate<br />
-	**[[2ftb]] - AmLFABP + oleate<br />
-	**[[2qo4]] – zLFABP + cholate – zebrafish<br />
-	**[[2qo5]], [[2qo6]] – zLFABP (mutant) + cholate <br />
-
-	*Adipocyte fatty acid-binding protein
-
-	**[[1tou]], [[2hnx]], [[3q6l]], [[3rzy]] - hAFABP<br />
-	**[[1tow]] - hAFABP + carbazole butanoic acid<br />
-	**[[2nnq]], [[3fr2]], [[3fr4]], [[3fr5]], [[5hz6]], [[5hz8]], [[5d45]], [[5d47]], [[5d48]], [[5d4a]], [[5edb]], [[5edc]], [[4nns]], [[4nnt]], [[5y0f]], [[5y0g]], [[5y0x]], [[5y12]], [[5y13]] - hAFABP + inhibitor<br />
-	**[[3p6c]] - hAFABP + citrate<br />
-	**[[3p6d]], [[3p6e]] - hAFABP + propionate derivative<br />
-	**[[3p6f]] - hAFABP + phenyl-butyrate<br />
-	**[[3p6g]], [[3p6h]] - hAFABP + ibuprofen<br />
-	**[[6ayl]] - hAFABP + fluorescein <br />
-	**[[1lib]], [[1alb]] – mAFABP<br />
-	[[1g7n]], [[1ab0]], [[1acd]] - mAFABP (mutant) <br />[[2qm9]] - mAFABP + troglitazone <br />
-	**[[2q9s]], [[1lid]], [[1lie]], [[1lif]], [[1adl]] - mAFABP + fatty acid<br />
-	**[[1g74]] - mAFABP (mutant) + fatty acid <br />
-	**[[3hk1]], [[3js1]], [[3jsq]] - mAFABP + inhibitor<br />
-	**[[1lic]], [[2ans]] – mAFABP + sulfonic acid derivative<br />
-	**[[1a18]] - mAFABP + phenanthroline <br />
-	**[[1a2d]] - mAFABP + pyridoxamine <br />
-	**[[5c0n]] - mAFABP + Fab <br />
-
-	*Flight muscle fatty acid-binding protein
-
-	**[[2flj]], [[1ftp]] - LMFABP – locust
-
-	*Muscle fatty acid-binding protein
-
-	**[[2hmb]] – hMFABP <br />
-	**[[1hmr]], [[1hms]], [[1hmt]] – hMFABP + fatty acid<br />
-
-	*Testis fatty acid-binding protein
-
-	**[[4a60]] - hTFABP
-
-	*Ileal bile acid-binding protein (Gastrotropin)
-
-	**[[1o1u]], [[5l8i]] – hIBABP <br />
-	**[[1o1v]] – hIBABP + cholytaurine<br />
-	**[[2mm3]], [[5l8o]] – hIBABP + cholate<br />
-	**[[5l8n]] – hIBABP + inhibitor<br />
-	**[[1eal]] – pIBABP - pig <br />
-	**[[1eio]] – pIBABP + cholate<br />
-	**[[3elx]] – zIBABP <br />
-	**[[3elz]], [[3em0]] – zIBABP + cholate<br />
-
-	*Other fatty acid-binding protein
-
-	**[[2poa]] - SmFABP (mutant) - ''Schistosoma mansoni'' – NMR<BR />
-	**[[1mdc]] – FABP – tobacco hornworm<br />
-	**[[4jgx]] - FABP – ''Yarrowia lipolytica''<br />
-	**[[1vyf]], [[1vyg]] – SmFABP + fatty acid<br />
-	**[[3w9k]] – FABP + fatty acid – ''Sulfolobus tokodaii''<br />
-	**[[2n93]] – FABP – ''Luciola cerata'' - NMR<br />
-	**[[5bvq]] – PpFABP – ''Pygoscelis papua'' <br />
-	**[[5bvs]], [[5bvt]] – PpFABP + fatty acid <br />
-	}}
	== References ==		== References ==
	<references/>		<references/>

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 10:05, 26 June 2019

Michal Harel — Wed, 26 Jun 2019 10:05:00 GMT

←Older revision		Revision as of 10:05, 26 June 2019
Line 10:		Line 10:

	The <scene name='48/487562/Cv/5'>FABP active site binds fatty acids</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}})<ref>PMID:10854433</ref>.		The <scene name='48/487562/Cv/5'>FABP active site binds fatty acids</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}})<ref>PMID:10854433</ref>.
		+
		+	==3D structures of fatty acid-binding protein==
		+	[[Fatty acid-binding protein 3D structures]]
		+
	</StructureSection>		</StructureSection>

Line 19:		Line 23:
	*Intestinal fatty acid-binding protein		*Intestinal fatty acid-binding protein

		+	**[[1kzw]], [[3ifb]] - hIFABP – human – NMR<BR />
		+	**[[1kzx]] - hIFABP (mutant) – NMR<BR />
	**[[1ael]], [[1a57]], [[1sa8]] - rIFABP – rat – NMR<BR />		**[[1ael]], [[1a57]], [[1sa8]] - rIFABP – rat – NMR<BR />
	**[[1t8v]] - rIFABP (mutant) – NMR<BR />		**[[1t8v]] - rIFABP (mutant) – NMR<BR />
	**[[1ifb]], [[1ifc]] - rIFABP <br />		**[[1ifb]], [[1ifc]] - rIFABP <br />
	**[[1dc9]] - rIFABP (mutant)<br />		**[[1dc9]] - rIFABP (mutant)<br />
-	**[[1kzw]], [[3ifb]] - hIFABP – human – NMR<BR />
-	**[[1kzx]] - hIFABP (mutant) – NMR<BR />

	*''Intestinal fatty acid-binding protein binary complex''		*''Intestinal fatty acid-binding protein binary complex''
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	**[[1b56]], [[1jjj]], [[4lkp]] - hEFABP <br />		**[[1b56]], [[1jjj]], [[4lkp]] - hEFABP <br />
	**[[4azr]], [[4lkt]] - hEFABP + fatty acid<br />		**[[4azr]], [[4lkt]] - hEFABP + fatty acid<br />
		+	**[[4azm]], [[5ur9]], [[5hz5]] - hEFABP + inhibitor<br />
	**[[4azn]], [[4azo]] - mEFABP <br />		**[[4azn]], [[4azo]] - mEFABP <br />
	**[[4azp]], [[4azq]] - mEFABP + fatty acid<br />		**[[4azp]], [[4azq]] - mEFABP + fatty acid<br />
-	**[[4azm]] - hEFABP + inhibitor<br />

	*Heart-type fatty acid-binding protein		*Heart-type fatty acid-binding protein

	**[[1g5w]] - hHFABP – NMR<BR />		**[[1g5w]] - hHFABP – NMR<BR />
-	**[[3rsw]], [[5ce4]] – hHFABP<br />	+	**[[3rsw]], [[5ce4]], [[6aq1]] – hHFABP<br />
	**[[3wbg]] – hHFABP + sulfonate derivative<br />		**[[3wbg]] – hHFABP + sulfonate derivative<br />
	**[[5hz9]] – hHFABP + inhibitor<br />		**[[5hz9]] – hHFABP + inhibitor<br />
	**[[3wvm]], [[4tjz]], [[4tkb]], [[4tkh]], [[4tkj]], [[4wbk]], [[3wxq]] - hHFABP + fatty acid<br />		**[[3wvm]], [[4tjz]], [[4tkb]], [[4tkh]], [[4tkj]], [[4wbk]], [[3wxq]] - hHFABP + fatty acid<br />
		+	**[[5b29]], [[5b28]], [[5b27]] - hHFABP (mutant) + fatty acid<br />
	**[[1bwy]] – HFABP – bovine<br />		**[[1bwy]] – HFABP – bovine<br />
	**[[5d8j]] – HFABP + Fab – mouse<br />		**[[5d8j]] – HFABP + Fab – mouse<br />
Line 55:		Line 60:
	**[[1fdq]], [[1jjx]] - hBFABP<br />		**[[1fdq]], [[1jjx]] - hBFABP<br />
	**[[1fe3]] - hBFABP + oleate<br />		**[[1fe3]] - hBFABP + oleate<br />
		+	**[[5ura]] - hBFABP + inhibitor <br />

	*Liver-type fatty acid-binding protein		*Liver-type fatty acid-binding protein

-	**[[1p6p]] - LFABP – toad<br />
-	**[[1tvq]], [[1mvg]] - cLFABP – chicken<br />
-	**[[1zry]] - cLFABP - NMR<BR />
	**[[2f73]], [[3stn]], [[3b2h]], [[3b2i]], [[3b2j]], [[3b2k]], [[3b2l]], [[3vg2]], [[3vg3]], [[3vg4]], [[3vg5]], [[3vg6]], [[3vg7]] - hLFABP<br />		**[[2f73]], [[3stn]], [[3b2h]], [[3b2i]], [[3b2j]], [[3b2k]], [[3b2l]], [[3vg2]], [[3vg3]], [[3vg4]], [[3vg5]], [[3vg6]], [[3vg7]] - hLFABP<br />
	**[[2py1]], [[2l67]], [[2l68]] - hLFABP – NMR<BR />		**[[2py1]], [[2l67]], [[2l68]] - hLFABP – NMR<BR />
		+	**[[1tvq]], [[1mvg]] - cLFABP – chicken<br />
		+	**[[1zry]] - cLFABP - NMR<BR />
	**[[2ju3]], [[2ju7]] - rLFABP – NMR<BR />		**[[2ju3]], [[2ju7]] - rLFABP – NMR<BR />
		+	**[[1p6p]] - LFABP – toad<br />
	**[[2ft9]] – AmLFABP - ''Ambystoma mexicanum''		**[[2ft9]] – AmLFABP - ''Ambystoma mexicanum''

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	**[[1tou]], [[2hnx]], [[3q6l]], [[3rzy]] - hAFABP<br />		**[[1tou]], [[2hnx]], [[3q6l]], [[3rzy]] - hAFABP<br />
-	**[[1lib]], [[1alb]] – mAFABP<br />
-	**[[1g7n]], [[1ab0]], [[1acd]] - mAFABP (mutant) <br />
	**[[1tow]] - hAFABP + carbazole butanoic acid<br />		**[[1tow]] - hAFABP + carbazole butanoic acid<br />
-	**[[2nnq]], [[3fr2]], [[3fr4]], [[3fr5]], [[5hz6]], [[5hz8]], [[5d45]], [[5d47]], [[5d48]], [[5d4a]], [[5edb]], [[5edc]], [[4nns]], [[4nnt]] - hAFABP + inhibitor<br />	+	**[[2nnq]], [[3fr2]], [[3fr4]], [[3fr5]], [[5hz6]], [[5hz8]], [[5d45]], [[5d47]], [[5d48]], [[5d4a]], [[5edb]], [[5edc]], [[4nns]], [[4nnt]], [[5y0f]], [[5y0g]], [[5y0x]], [[5y12]], [[5y13]] - hAFABP + inhibitor<br />
	**[[3p6c]] - hAFABP + citrate<br />		**[[3p6c]] - hAFABP + citrate<br />
	**[[3p6d]], [[3p6e]] - hAFABP + propionate derivative<br />		**[[3p6d]], [[3p6e]] - hAFABP + propionate derivative<br />
	**[[3p6f]] - hAFABP + phenyl-butyrate<br />		**[[3p6f]] - hAFABP + phenyl-butyrate<br />
	**[[3p6g]], [[3p6h]] - hAFABP + ibuprofen<br />		**[[3p6g]], [[3p6h]] - hAFABP + ibuprofen<br />
-	**[[2qm9]] - mAFABP + troglitazone <br />	+	**[[6ayl]] - hAFABP + fluorescein <br />
		+	**[[1lib]], [[1alb]] – mAFABP<br />
		+	[[1g7n]], [[1ab0]], [[1acd]] - mAFABP (mutant) <br />[[2qm9]] - mAFABP + troglitazone <br />
	**[[2q9s]], [[1lid]], [[1lie]], [[1lif]], [[1adl]] - mAFABP + fatty acid<br />		**[[2q9s]], [[1lid]], [[1lie]], [[1lif]], [[1adl]] - mAFABP + fatty acid<br />
	**[[1g74]] - mAFABP (mutant) + fatty acid <br />		**[[1g74]] - mAFABP (mutant) + fatty acid <br />
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	*Ileal bile acid-binding protein (Gastrotropin)		*Ileal bile acid-binding protein (Gastrotropin)

-	**[[3elx]] – zIBABP <br />
-	**[[3elz]], [[3em0]] – zIBABP + cholate<br />
-	**[[1eal]] – pIBABP - pig <br />
-	**[[1eio]] – pIBABP + cholate<br />
	**[[1o1u]], [[5l8i]] – hIBABP <br />		**[[1o1u]], [[5l8i]] – hIBABP <br />
	**[[1o1v]] – hIBABP + cholytaurine<br />		**[[1o1v]] – hIBABP + cholytaurine<br />
-	**[[2mm3]], [[~~5i8o~~]] – hIBABP + cholate<br />	+	**[[2mm3]], [[5l8o]] – hIBABP + cholate<br />
-	**[[~~5i8n~~]] – hIBABP + inhibitor<br />	+	**[[5l8n]] – hIBABP + inhibitor<br />
		+	**[[1eal]] – pIBABP - pig <br />
		+	**[[1eio]] – pIBABP + cholate<br />
		+	**[[3elx]] – zIBABP <br />
		+	**[[3elz]], [[3em0]] – zIBABP + cholate<br />

	*Other fatty acid-binding protein		*Other fatty acid-binding protein

Alexander Berchansky at 11:04, 17 March 2019

Alexander Berchansky — Sun, 17 Mar 2019 11:04:23 GMT

←Older revision		Revision as of 11:04, 17 March 2019
Line 9:		Line 9:
	== Structural insights ==		== Structural insights ==

-	The <scene name='48/487562/Cv/2'>FABP active site binds fatty acids</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}})<ref>PMID:10854433</ref>.	+	The <scene name='48/487562/Cv/5'>FABP active site binds fatty acids</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}})<ref>PMID:10854433</ref>.
	</StructureSection>		</StructureSection>

Alexander Berchansky at 09:21, 14 May 2017

Alexander Berchansky — Sun, 14 May 2017 09:21:44 GMT

←Older revision		Revision as of 09:21, 14 May 2017
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-	<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/3' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>	+	<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/4' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>

	'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis.		'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis.

Michal Harel at 09:07, 14 May 2017

Michal Harel — Sun, 14 May 2017 09:07:00 GMT

←Older revision		Revision as of 09:07, 14 May 2017
Line 112:		Line 112:
	**[[4a60]] - hTFABP		**[[4a60]] - hTFABP

-	*Ileal bile acid-binding protein	+	*Ileal bile acid-binding protein (Gastrotropin)

	**[[3elx]] – zIBABP <br />		**[[3elx]] – zIBABP <br />
	**[[3elz]], [[3em0]] – zIBABP + cholate<br />		**[[3elz]], [[3em0]] – zIBABP + cholate<br />
		+	**[[1eal]] – pIBABP - pig <br />
		+	**[[1eio]] – pIBABP + cholate<br />
		+	**[[1o1u]], [[5l8i]] – hIBABP <br />
		+	**[[1o1v]] – hIBABP + cholytaurine<br />
		+	**[[2mm3]], [[5i8o]] – hIBABP + cholate<br />
		+	**[[5i8n]] – hIBABP + inhibitor<br />

	*Other fatty acid-binding protein		*Other fatty acid-binding protein

Michal Harel at 10:13, 22 December 2016

Michal Harel — Thu, 22 Dec 2016 10:13:20 GMT

←Older revision		Revision as of 10:13, 22 December 2016
Line 28:		Line 28:
	*''Intestinal fatty acid-binding protein binary complex''		*''Intestinal fatty acid-binding protein binary complex''

-	**[[3akm]] - hIFABP + fatty acid analog<br />	+	**[[3akm]], [[2mo5]] - hIFABP + fatty acid analog<br />
		+	**[[2mji]] - hIFABP + ketorolac - NMR<br />
	**[[3akn]], [[1icm]], [[1icn]], [[2ifb]] - rIFABP + fatty acid analog<br />		**[[3akn]], [[1icm]], [[1icn]], [[2ifb]] - rIFABP + fatty acid analog<br />
	**[[1ure]] - rIFABP + palmitate – NMR<BR />		**[[1ure]] - rIFABP + palmitate – NMR<BR />
Line 34:		Line 35:
	*Epidermal fatty acid-binding protein		*Epidermal fatty acid-binding protein

-	**[[1b56]], [[1jjj]] - hEFABP <br />	+	**[[1b56]], [[1jjj]], [[4lkp]] - hEFABP <br />
-	**[[4azr]] - hEFABP + fatty acid<br />	+	**[[4azr]], [[4lkt]] - hEFABP + fatty acid<br />
	**[[4azn]], [[4azo]] - mEFABP <br />		**[[4azn]], [[4azo]] - mEFABP <br />
	**[[4azp]], [[4azq]] - mEFABP + fatty acid<br />		**[[4azp]], [[4azq]] - mEFABP + fatty acid<br />
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	**[[1g5w]] - hHFABP – NMR<BR />		**[[1g5w]] - hHFABP – NMR<BR />
-	**[[3rsw]] – hHFABP<br />	+	**[[3rsw]], [[5ce4]] – hHFABP<br />
	**[[3wbg]] – hHFABP + sulfonate derivative<br />		**[[3wbg]] – hHFABP + sulfonate derivative<br />
		+	**[[5hz9]] – hHFABP + inhibitor<br />
		+	**[[3wvm]], [[4tjz]], [[4tkb]], [[4tkh]], [[4tkj]], [[4wbk]], [[3wxq]] - hHFABP + fatty acid<br />
	**[[1bwy]] – HFABP – bovine<br />		**[[1bwy]] – HFABP – bovine<br />
		+	**[[5d8j]] – HFABP + Fab – mouse<br />

	*Brain-type fatty acid-binding protein		*Brain-type fatty acid-binding protein
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	**[[1g7n]], [[1ab0]], [[1acd]] - mAFABP (mutant) <br />		**[[1g7n]], [[1ab0]], [[1acd]] - mAFABP (mutant) <br />
	**[[1tow]] - hAFABP + carbazole butanoic acid<br />		**[[1tow]] - hAFABP + carbazole butanoic acid<br />
-	**[[2nnq]], [[3fr2]], [[3fr4]], [[3fr5]] - hAFABP + inhibitor<br />	+	**[[2nnq]], [[3fr2]], [[3fr4]], [[3fr5]], [[5hz6]], [[5hz8]], [[5d45]], [[5d47]], [[5d48]], [[5d4a]], [[5edb]], [[5edc]], [[4nns]], [[4nnt]] - hAFABP + inhibitor<br />
	**[[3p6c]] - hAFABP + citrate<br />		**[[3p6c]] - hAFABP + citrate<br />
	**[[3p6d]], [[3p6e]] - hAFABP + propionate derivative<br />		**[[3p6d]], [[3p6e]] - hAFABP + propionate derivative<br />
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	**[[1a18]] - mAFABP + phenanthroline <br />		**[[1a18]] - mAFABP + phenanthroline <br />
	**[[1a2d]] - mAFABP + pyridoxamine <br />		**[[1a2d]] - mAFABP + pyridoxamine <br />
		+	**[[5c0n]] - mAFABP + Fab <br />

	*Flight muscle fatty acid-binding protein		*Flight muscle fatty acid-binding protein
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	**[[1vyf]], [[1vyg]] – SmFABP + fatty acid<br />		**[[1vyf]], [[1vyg]] – SmFABP + fatty acid<br />
	**[[3w9k]] – FABP + fatty acid – ''Sulfolobus tokodaii''<br />		**[[3w9k]] – FABP + fatty acid – ''Sulfolobus tokodaii''<br />
		+	**[[2n93]] – FABP – ''Luciola cerata'' - NMR<br />
		+	**[[5bvq]] – PpFABP – ''Pygoscelis papua'' <br />
		+	**[[5bvs]], [[5bvt]] – PpFABP + fatty acid <br />
	}}		}}
	== References ==		== References ==

Michal Harel at 09:22, 22 December 2016

Michal Harel — Thu, 22 Dec 2016 09:22:26 GMT

←Older revision		Revision as of 09:22, 22 December 2016
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	<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/3' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>		<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/3' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>

-	'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis~~; '''EXFABP''' is extracellular~~.	+	'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis.

	== Relevance ==		== Relevance ==
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	**[[3elx]] – zIBABP <br />		**[[3elx]] – zIBABP <br />
	**[[3elz]], [[3em0]] – zIBABP + cholate<br />		**[[3elz]], [[3em0]] – zIBABP + cholate<br />
-
-	*Extracellular fatty acid-binding protein
-
-	**[[2kt4]] - qEXFABP – quail<br />
-	**[[2lbv]] - qEXFABS + enterobactin<br />
-	**[[3sao]] - cEXFABP + myristoyl lysophosphatidic acid

	*Other fatty acid-binding protein		*Other fatty acid-binding protein

Alexander Berchansky at 12:12, 25 January 2016

Alexander Berchansky — Mon, 25 Jan 2016 12:12:03 GMT

←Older revision		Revision as of 12:12, 25 January 2016
Line 1:		Line 1:
-	<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/1' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>	+	<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/3' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>

	'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis; '''EXFABP''' is extracellular.		'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis; '''EXFABP''' is extracellular.
Line 9:		Line 9:
	== Structural insights ==		== Structural insights ==

-	The <scene name='48/487562/Cv/2'>FABP active site binds fatty acids</scene><ref>PMID:10854433</ref>.	+	The <scene name='48/487562/Cv/2'>FABP active site binds fatty acids</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}})<ref>PMID:10854433</ref>.
	</StructureSection>		</StructureSection>

Alexander Berchansky at 12:06, 25 January 2016

Alexander Berchansky — Mon, 25 Jan 2016 12:06:17 GMT

←Older revision		Revision as of 12:06, 25 January 2016
Line 9:		Line 9:
	== Structural insights ==		== Structural insights ==

-	The FABP active site binds fatty acids<ref>PMID:10854433</ref>.	+	The <scene name='48/487562/Cv/2'>FABP active site binds fatty acids</scene><ref>PMID:10854433</ref>.
	</StructureSection>		</StructureSection>

Alexander Berchansky at 11:47, 25 January 2016

Alexander Berchansky — Mon, 25 Jan 2016 11:47:47 GMT

←Older revision		Revision as of 11:47, 25 January 2016
Line 1:		Line 1:
-	<StructureSection load='1fe3' size='350' side='right' scene='' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>	+	<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/1' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '>

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	'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis; '''EXFABP''' is extracellular.		'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis; '''EXFABP''' is extracellular.