Fatty acid synthesis - Revision history

Alexander Berchansky at 09:35, 8 December 2022

Alexander Berchansky — Thu, 08 Dec 2022 09:35:06 GMT

←Older revision		Revision as of 09:35, 8 December 2022
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	Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>palmitic acid</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.		Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>palmitic acid</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.

-	Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway.	+	Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the [[glycolytic pathway]]. '''Pyruvate decarboxylation or pyruvate oxidation''', also known as the link reaction (or oxidative decarboxylation of pyruvate), is the conversion of <scene name='39/392339/Cv1/11'>pyruvate</scene> into <scene name='43/430893/Cv/2'>Acetyl-CoA</scene> by the enzyme complex pyruvate dehydrogenase complex (see [[Pyruvate dehydrogenase]]).

	''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''		''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''

Alexander Berchansky at 09:26, 8 December 2022

Alexander Berchansky — Thu, 08 Dec 2022 09:26:54 GMT

←Older revision		Revision as of 09:26, 8 December 2022
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	Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>palmitic acid</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.		Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>palmitic acid</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.

-	~~Acetyl~~-CoA is ~~coming~~ from ~~[[Citric Acid Cycle]]~~.	+	Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway.

	''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''		''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''

Alexander Berchansky at 09:24, 8 December 2022

Alexander Berchansky — Thu, 08 Dec 2022 09:24:57 GMT

←Older revision		Revision as of 09:24, 8 December 2022
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	'''Straight-chain fatty acids'''		'''Straight-chain fatty acids'''

-	Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>~~TextToBeDisplayed~~</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.	+	Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>palmitic acid</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.

	Acetyl-CoA is coming from [[Citric Acid Cycle]].		Acetyl-CoA is coming from [[Citric Acid Cycle]].

Alexander Berchansky at 14:11, 7 December 2022

Alexander Berchansky — Wed, 07 Dec 2022 14:11:31 GMT

←Older revision		Revision as of 14:11, 7 December 2022
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	'''Straight-chain fatty acids'''		'''Straight-chain fatty acids'''

-	Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon ~~palmitic acid~~ is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.	+	Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>TextToBeDisplayed</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.

	Acetyl-CoA is coming from [[Citric Acid Cycle]].		Acetyl-CoA is coming from [[Citric Acid Cycle]].

Alexander Berchansky at 15:24, 6 December 2022

Alexander Berchansky — Tue, 06 Dec 2022 15:24:35 GMT

←Older revision		Revision as of 15:24, 6 December 2022
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	''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''		''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''
	*[[Acyl carrier protein]] (ACP).		*[[Acyl carrier protein]] (ACP).
-	Acetyl-CoA + [acyl-carrier-protein] ⇌ CoA + acetyl-[acyl-carrier-protein]	+	<scene name='43/430893/Cv/2'>Acetyl-CoA</scene> + [acyl-carrier-protein] ⇌ CoA + acetyl-[acyl-carrier-protein]

	''Step 2 Malonyl CoA:ACP transacylase; (acyl-carrier-protein) S-malonyltransferase; EC 2.3.1.39''		''Step 2 Malonyl CoA:ACP transacylase; (acyl-carrier-protein) S-malonyltransferase; EC 2.3.1.39''

Alexander Berchansky at 15:18, 6 December 2022

Alexander Berchansky — Tue, 06 Dec 2022 15:18:03 GMT

←Older revision		Revision as of 15:18, 6 December 2022
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	''Step 2 Malonyl CoA:ACP transacylase; (acyl-carrier-protein) S-malonyltransferase; EC 2.3.1.39''		''Step 2 Malonyl CoA:ACP transacylase; (acyl-carrier-protein) S-malonyltransferase; EC 2.3.1.39''

-	malonyl-CoA + acyl carrier protein ⇌ CoA + malonyl-[acyl-carrier-protein]	+	<scene name='92/928693/Cv/1'>malonyl-CoA</scene> + acyl carrier protein ⇌ CoA + malonyl-[acyl-carrier-protein]

	''Step 3 3-ketoacyl-ACP synthase; Beta-ketoacyl-ACP synthase I; Acyl carrier protein synthase; EC 2.3.1.41''		''Step 3 3-ketoacyl-ACP synthase; Beta-ketoacyl-ACP synthase I; Acyl carrier protein synthase; EC 2.3.1.41''

Alexander Berchansky at 12:25, 29 September 2022

Alexander Berchansky — Thu, 29 Sep 2022 12:25:59 GMT

←Older revision		Revision as of 12:25, 29 September 2022
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	Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon palmitic acid is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.		Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon palmitic acid is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria.
		+
		+	Acetyl-CoA is coming from [[Citric Acid Cycle]].

	''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''		''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38''

Alexander Berchansky at 10:27, 29 September 2022

Alexander Berchansky — Thu, 29 Sep 2022 10:27:08 GMT

←Older revision		Revision as of 10:27, 29 September 2022
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	'''Conversion of carbohydrates into fatty acids'''		'''Conversion of carbohydrates into fatty acids'''

-	In humans, fatty acids are formed from carbohydrates predominantly in the liver and adipose tissue, as well as in the mammary glands during lactation.	+	In humans, fatty acids are formed from carbohydrates predominantly in the liver and adipose tissue, as well as in the mammary glands during lactation. The pyruvate produced by glycolysis is an important intermediary in the conversion of carbohydrates into fatty acids (see [[Lipids: structure and classification]]) and cholesterol.

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 10:24, 29 September 2022

Alexander Berchansky — Thu, 29 Sep 2022 10:24:30 GMT

←Older revision		Revision as of 10:24, 29 September 2022
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	*[[Enoyl-Acyl-Carrier Protein Reductase]]		*[[Enoyl-Acyl-Carrier Protein Reductase]]
		+
		+	'''Conversion of carbohydrates into fatty acids'''
		+
		+	In humans, fatty acids are formed from carbohydrates predominantly in the liver and adipose tissue, as well as in the mammary glands during lactation.

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 10:02, 29 September 2022

Alexander Berchansky — Thu, 29 Sep 2022 10:02:18 GMT

←Older revision		Revision as of 10:02, 29 September 2022
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	*[[Beta-hydroxyacyl-acyl carrier protein dehydratase]]		*[[Beta-hydroxyacyl-acyl carrier protein dehydratase]]
		+
		+	''Step 6 Enoyl-ACP reductase; EC 1.3.1.9''
		+
		+	*[[Enoyl-Acyl-Carrier Protein Reductase]]

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>