Ferredoxin - Revision history

Michal Harel at 08:28, 27 June 2019

Michal Harel — Thu, 27 Jun 2019 08:28:32 GMT

←Older revision		Revision as of 08:28, 27 June 2019
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	</StructureSection>		</StructureSection>

-	==3D structures of ferredoxin==
-
-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*2Fe-2S containing ferredoxins
-
-	**[[2kaj]], [[1dox]], [[1doy]] – SyFd +Ga – ''Synechocystis'' – NMR <br />
-	**[[3hui]], [[4ltu]] – Fd – ''Rhodopseudomonas palustris'' <br />
-	**[[1off]] – SyFd <br />
-	**[[3gce]] – Fd – ''Nocardioides aromaticivorans'' <br />
-	**[[3lxf]] – Fd – ''Novosphingobium aromaticivorans''<br />
-	**[[2e4p]], [[2e4q]] - Fd – ''Pseudomonas sp.'' <br />
-	**[[2q3w]], [[1vm9]] - PmFd (mutant) – ''Pseudomonas mendocina'' <br />
-	**[[2i7f]], [[1uwm]] - RcFd – ''Rhodobacter capsulatus'' <br />
-	**[[1e9m]] – RcFd - NMR<br />
-	**[[1rfk]], [[3p63]] - Fd – ''Cyanobacterium'' ''masticogladus laminosus'' <br />
-	**[[1vck]] - Fd – ''Pseudomonas resinovorans'' <br />
-	**[[1wri]], [[1frr]] - Fd – E''quisetum arvense'' <br />
-	**[[1sjg]] - PmFd– NMR <br />
-	**[[1iue]] - Fd– ''Plasmodium falciparum'' <br />
-	**[[1m2a]] – AeFd – ''Aquifex aeolicu''s <br />
-	**[[1m2b]], [[1m2d]], [[1f37]], [[1f5b]], [[1f5c]] – AeFd (mutant) <br />
-	**[[1l5p]] – Fd – ''Trichomonas vaginali''s <br />
-	**[[1i7h]] - Fd – ''Escherichia coli'' <br />
-	**[[1czp]], [[1qt9]], [[1frd]], [[1fxa]] - aFd– ''anabaena'' <br />
-	**[[1j7a]], [[1j7b]], [[1j7c]] , [[1qoa]], [[1qob]], [[1qof]], [[1qog]]- aFd (mutant) <br />
-	**[[1e0z]] – Fd – ''Halobacterium salinarium'' <br />
-	**[[1e10]] - Fd – ''Halobacterium halobium''<br />
-	**[[1pfd]] – Fd – ''Petroselinum crispum'' – NMR <br />
-	**[[1a70]] - Fd (mutant) – ''Spinacia oleracea'' <br />
-	**[[1awd]] - Fd – ''Chlorella fusca'' <br />
-	**[[2cjn]], [[2cjo]], [[1roe]] – SyFd – NMR <br />
-	**[[1rof]], [[5aui]], [[5auk]] – SyFd – ''Synechococcus elongates'' <br />
-	**[[1doi]] - Fd – ''Haloarcula marismortui'' <br />
-	**[[4fxc]] – Fd – ''Spirulina platensi''s <br />
-	**[[1fxi]], [[3av8]] – Fd – ''Aphanothece sacrum'' <br />
-	**[[3dqy]], [[2qpz]], [[3ah7]] - Fd – ''Pseudomonas putida'' <br />
-	**[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />
-	**[[3b2f]], [[5h57]] – mFd – maize<br />
-	**[[3w5u]], [[3w5v]], [[1gaq]], [[5h5j]] – mFd + ferredoxin-NADP reductase<br />
-	**[[5h92]], [[5h8y]] – mFd + sulfite reductase<br />
-	**[[3b2g]] – Fd – ''Leptolyngbya boryana''<br />
-	**[[2mh7]] – Fd – ''Chlamydomonas reinhardtii''<br />
-	**[[1ewy]] – Fd + ferredoxin-NADP reductase - ''Nostoc''<br />
-	**[[5ffi]], [[5abr]] - AvFd – ''Azotobacter vinelandii''<br />
-	**[[5bok]] - Fd – ''Diaphorobacter''<br />
-	**[[4zhp]] - Fd – potato<br />
-	**[[4zho]] – AtFd-2 – ''Arabidopsis thaliana''<br />
-	**[[6b03]], [[6b05]], [[6brs]] – AtFd-2 + zinc protease<br />
-	**[[6e6s]], [[6e6r]], [[6e6q]] – PaFd (mutant)_- ''Pseudomonas aeruginosa''<br />
-
-	*4Fe-4S containing ferredoxins
-
-	**[[3eun]] – AvFd – ''Allochromatium vinosum'' <br />
-	**[[3exy]] - AvFd (mutant) <br />
-	**[[2vkr]] - Fd+Zn – ''Acidianus ambivalens'' <br />
-	**[[2z8q]] - PfFd (mutant) – ''Pyrococcus furiosus'' <br />
-	**[[1siz]] - PfFd<br >
-	**[[3pni]] - PfFd (mutant)<br />
-	**[[2fgo]] - PaFd <br />
-	**[[1iqz]], [[1ir0]] - BtFd – ''Bacillus thermoproteolyticus'' <br />
-	**[[1rgv]] - Fd – ''Thauera aromatica'' <br />
-	**[[1dax]], [[1dfd]] – DaFd – ''Desulfovibrio africanus'' – NMR <br />
-	**[[1fxr]] - DaFd <br />
-	**[[1vjw]] – Fd – ''Thermotoga maritima'' <br />
-	**[[1dwl]] – Fd – ''Desulfomicrobium norvegicum''<br />
-
-	*3Fe-4S containing ferredoxins
-
-	**[[2v2k]] – Fd – ''Mycobacterium smegmatis'' <br />
-	**[[1wtf]] - BtFd (mutant) <br />
-	**[[1sj1]] - PfFd <br />
-	**[[1fxd]] - DgFd – ''Desulfovibrio gigas'' <br />
-	**[[1f2g]] – DgFd – NMR <br />
-	**[[1xer]] - Fd – ''Sulfolobus tokodaii'' <br />
-
-	*4Fe-4S+3Fe-4S containing ferredoxins
-
-	**[[1gao]], [[6fdr]], [[7fd1]], [[7fdr]], [[1axq]], [[6fd1]], [[1frh]], [[1fri]],[[1frj]], [[1frk]], [[1frl]], [[1frm]], [[1fda]], [[1fdb]], [[1fdd]], [[5fd1]], [[1fer]] – AvFd – ''Azotobacter vinelandii'' <br />
-	**[[1pc4]], [[1pc5]], [[1g6b]], [[1g3o]], [[1ff2]], [[1b0v]], [[1d3w]], [[1b0t]], [[1a6l]], [[1ftc]], [[1frx]], [[2fd2]], [[1fd2]] - AvFd (mutant) <br />
-	**[[1h98]] – Fd – ''Thermus thermophilus'' <br />
-	**[[1a8p]], [[1bd6]], [[1bc6]] - BsFd – ''Bacillus schlegelii'' – NMR <br />
-
-	*4Fe-4S+4Fe-4S containing ferredoxins
-
-	**[[1dur]] – Fd – ''Peptoniphilus asaccarolyticus'' <br />
-	**[[1bwe]], [[1bqx]] - BsFd (mutant) – NMR <br />
-	**[[2fdn]], [[1fca]] , [[1fdn]] - Fd – ''Clostridium acidi-urici'' <br />
-	**[[1blu]] - Fd – ''Chromatium vinosum'' <br />
-	**[[1clf]] – Fd – ''Clostridium pasteurianum'' – NMR <br />
-
-	*Adrenoredoxin
-
-	**[[2mjd]], [[2mje]] – yADR – yeast<br />
-	**[[2jqr]] – yADR Fd domain (mutant)+cytochrome c (mutant) – NMR <br />
-	**[[2bt6]] – cADR1 modified – cow <br />
-	**[[1l6u]], [[1l6v]] – cADR1 – NMR <br />
-	**[[1e6e]] – cADR (mutant)+ADR reductase <br />
-	**[[1cje]], [[1ayf]] - cADR <br />
-	**[[3na0]], [[3n9y]], [[3n9z]], [[3na1]] - hADR +cholesterol side-chain cleavage enzyme – human<br />
-	**[[3p1m]] - hADR<br />
-	**[[5uj5]] – ADR – ''Encephalitozoon cuniculi''<br />
-
-	*Putidaredoxin
-
-	**[[1yji]], [[1yjj]], [[1pdx]] – PpPUT – NMR <br />
-	**[[3lb8]] – PpPUT (mutant)+PUT reductase <br />
-	**[[1xln]], [[1xlo]], [[1xlp]], [[1xlq]], [[1r7s]], [[1oqq]], [[1oqr]] - PpPUT (mutant) <br />
-	**[[1gpx]], [[1put]]- PpPUT (mutant) - NMR <br />
-	**[[4jws]] - PpPUT + cytochrome P450cam<br />
-	**[[3w9c]], [[4jwu]] - PpPUT (mutant) + cytochrome P450cam<br />
-	**[[2m56]] - PpPUT (mutant) + cytochrome P450cam - NMR<br />
-	**[[4jx1]] - PpPUT (mutant) + cytochrome P450cam + camphor + hydroxycamphor<br />
-
-	*Terpredoxin
-
-	**[[1b9r]] – TER – ''Pseudomonas'' - NMR <br />
-	}}
	==References==		==References==
	<references/>		<references/>

Michal Harel at 08:27, 27 June 2019

Michal Harel — Thu, 27 Jun 2019 08:27:09 GMT

←Older revision		Revision as of 08:27, 27 June 2019
Line 1:		Line 1:
	<StructureSection load='2z8q' size='450' side='right' scene='' caption='Ferredoxin with Fe4S4 cluster complex with cobalt hexamine (PDB code [[2z8q]])'>		<StructureSection load='2z8q' size='450' side='right' scene='' caption='Ferredoxin with Fe4S4 cluster complex with cobalt hexamine (PDB code [[2z8q]])'>

		+	==Function==

	[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster. It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced. The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters. '''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland. '''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group.		[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster. It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced. The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters. '''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland. '''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group.
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	The crystal structure of the ''Pyrococcus furiosus'' (Pf) ferredoxin (Fd) D14C variant with the novel [AgFe<sub>3</sub>S<sub>4</sub>] heterometallic cluster was determined to 1.95 Å resolution (PBD entry [[4dhv]]), being the first reported structure of an engineered heterometallic iron-sulfur protein.		The crystal structure of the ''Pyrococcus furiosus'' (Pf) ferredoxin (Fd) D14C variant with the novel [AgFe<sub>3</sub>S<sub>4</sub>] heterometallic cluster was determined to 1.95 Å resolution (PBD entry [[4dhv]]), being the first reported structure of an engineered heterometallic iron-sulfur protein.
	The crystal structure of the <scene name='Journal:JBIC:19/Cv/4'>monomeric form</scene> shows that the <scene name='Journal:JBIC:19/Cv/6'>silver (I) ion is part of the cluster</scene> (clearly seen on the electron density map), as predicted from previous spectroscopic and electrochemical studies. The heterometal is coordinated to the <scene name='Journal:JBIC:19/Cv/5'>three inorganic sulfides of the cluster</scene> and to the <scene name='Journal:JBIC:19/Cv/7'>thiolate group of residue 14</scene> (residues <scene name='Journal:JBIC:19/Cv/8'>Cys11, Cys17 and Cys56</scene> are coordinated with Fe ions of heterometal), <scene name='Journal:JBIC:19/Cv/9'>replacing the aboriginal Fe ion in the all-iron coordinated</scene> [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]], <span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>) and completing the incomplete cuboidal cluster present in the [Fe<sub>3</sub>S<sub>4</sub>] WT Pf Fd (PDB: [[1sj1]]) and its D14C (PDB: [[3pni]]) variant (for more details see also [http://proteopedia.org/w/Journal:JBIC:10 "Crystal structures of the all cysteinyl coordinated D14C variant of ''Pyrococcus furiosus'' ferredoxin: (4Fe-4S) <-> (3Fe-4S) cluster conversion"]). Structure alignment of backbone atoms from the heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein and the homometallic [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]]) shows <scene name='Journal:JBIC:19/Cv/10'>very minor differences</scene>, i.e. the root mean square deviation (RMSD) is 0.4 – 0.7 Å, observed due to the alternate conformation of the main chain atoms, flexible loops and small changes at the N- and C-termini (<span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>). <scene name='Journal:JBIC:19/Cv/14'>More significant difference</scene> can be seen in the superimposed Fe–S clusters (atom colors corresponding to <span style="color:yellow;background-color:black;font-weight:bold;">yellow: S</span>, <span style="color:orange;background-color:black;font-weight:bold;">orange: Fe</span>, <span style="color:gray;background-color:black;font-weight:bold;">gray: Ag</span>) from these two variants, which is due to the presence of the second row transition metal ion (Ag) coordinated to the four S-ligands, i.e. the presence of Ag results in a distorted geometry of the cluster compared to the all-iron arrangement, <scene name='Journal:JBIC:19/Cv/12'>because to the longer</scene> Ag – S bond lengths compared to Fe – S bonds. However, the S – Ag – S <scene name='Journal:JBIC:19/Cv/13'>bond angles</scene> are still close to the expected 90° for a primitive cubic system.		The crystal structure of the <scene name='Journal:JBIC:19/Cv/4'>monomeric form</scene> shows that the <scene name='Journal:JBIC:19/Cv/6'>silver (I) ion is part of the cluster</scene> (clearly seen on the electron density map), as predicted from previous spectroscopic and electrochemical studies. The heterometal is coordinated to the <scene name='Journal:JBIC:19/Cv/5'>three inorganic sulfides of the cluster</scene> and to the <scene name='Journal:JBIC:19/Cv/7'>thiolate group of residue 14</scene> (residues <scene name='Journal:JBIC:19/Cv/8'>Cys11, Cys17 and Cys56</scene> are coordinated with Fe ions of heterometal), <scene name='Journal:JBIC:19/Cv/9'>replacing the aboriginal Fe ion in the all-iron coordinated</scene> [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]], <span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>) and completing the incomplete cuboidal cluster present in the [Fe<sub>3</sub>S<sub>4</sub>] WT Pf Fd (PDB: [[1sj1]]) and its D14C (PDB: [[3pni]]) variant (for more details see also [http://proteopedia.org/w/Journal:JBIC:10 "Crystal structures of the all cysteinyl coordinated D14C variant of ''Pyrococcus furiosus'' ferredoxin: (4Fe-4S) <-> (3Fe-4S) cluster conversion"]). Structure alignment of backbone atoms from the heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein and the homometallic [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]]) shows <scene name='Journal:JBIC:19/Cv/10'>very minor differences</scene>, i.e. the root mean square deviation (RMSD) is 0.4 – 0.7 Å, observed due to the alternate conformation of the main chain atoms, flexible loops and small changes at the N- and C-termini (<span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>). <scene name='Journal:JBIC:19/Cv/14'>More significant difference</scene> can be seen in the superimposed Fe–S clusters (atom colors corresponding to <span style="color:yellow;background-color:black;font-weight:bold;">yellow: S</span>, <span style="color:orange;background-color:black;font-weight:bold;">orange: Fe</span>, <span style="color:gray;background-color:black;font-weight:bold;">gray: Ag</span>) from these two variants, which is due to the presence of the second row transition metal ion (Ag) coordinated to the four S-ligands, i.e. the presence of Ag results in a distorted geometry of the cluster compared to the all-iron arrangement, <scene name='Journal:JBIC:19/Cv/12'>because to the longer</scene> Ag – S bond lengths compared to Fe – S bonds. However, the S – Ag – S <scene name='Journal:JBIC:19/Cv/13'>bond angles</scene> are still close to the expected 90° for a primitive cubic system.
		+
		+	==3D structures of ferredoxin==
		+	[[Ferredoxin 3D structures]]
		+
	</StructureSection>		</StructureSection>

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	**[[5bok]] - Fd – ''Diaphorobacter''<br />		**[[5bok]] - Fd – ''Diaphorobacter''<br />
	**[[4zhp]] - Fd – potato<br />		**[[4zhp]] - Fd – potato<br />
-	**[[4zho]] – Fd-2 – ''Arabidopsis thaliana''<br />	+	**[[4zho]] – AtFd-2 – ''Arabidopsis thaliana''<br />
-		+	**[[6b03]], [[6b05]], [[6brs]] – AtFd-2 + zinc protease<br />
		+	**[[6e6s]], [[6e6r]], [[6e6q]] – PaFd (mutant)_- ''Pseudomonas aeruginosa''<br />

	*4Fe-4S containing ferredoxins		*4Fe-4S containing ferredoxins
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	**[[1siz]] - PfFd<br >		**[[1siz]] - PfFd<br >
	**[[3pni]] - PfFd (mutant)<br />		**[[3pni]] - PfFd (mutant)<br />
-	**[[2fgo]] - ~~Fd– ''Pseudomonas aeruginosa''~~ <br />	+	**[[2fgo]] - PaFd <br />
	**[[1iqz]], [[1ir0]] - BtFd – ''Bacillus thermoproteolyticus'' <br />		**[[1iqz]], [[1ir0]] - BtFd – ''Bacillus thermoproteolyticus'' <br />
	**[[1rgv]] - Fd – ''Thauera aromatica'' <br />		**[[1rgv]] - Fd – ''Thauera aromatica'' <br />

Michal Harel at 09:50, 14 May 2017

Michal Harel — Sun, 14 May 2017 09:50:13 GMT

←Older revision		Revision as of 09:50, 14 May 2017
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	**[[1awd]] - Fd – ''Chlorella fusca'' <br />		**[[1awd]] - Fd – ''Chlorella fusca'' <br />
	**[[2cjn]], [[2cjo]], [[1roe]] – SyFd – NMR <br />		**[[2cjn]], [[2cjo]], [[1roe]] – SyFd – NMR <br />
-	**[[1rof]] – SyFd – ''Synechococcus elongates'' <br />	+	**[[1rof]], [[5aui]], [[5auk]] – SyFd – ''Synechococcus elongates'' <br />
	**[[1doi]] - Fd – ''Haloarcula marismortui'' <br />		**[[1doi]] - Fd – ''Haloarcula marismortui'' <br />
	**[[4fxc]] – Fd – ''Spirulina platensi''s <br />		**[[4fxc]] – Fd – ''Spirulina platensi''s <br />
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	**[[3dqy]], [[2qpz]], [[3ah7]] - Fd – ''Pseudomonas putida'' <br />		**[[3dqy]], [[2qpz]], [[3ah7]] - Fd – ''Pseudomonas putida'' <br />
	**[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />		**[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />
-	**[[3b2f]] – mFd – maize<br />	+	**[[3b2f]], [[5h57]] – mFd – maize<br />
-	**[[3w5u]], [[3w5v]], [[1gaq]] – mFd + ferredoxin-NADP reductase<br />	+	**[[3w5u]], [[3w5v]], [[1gaq]], [[5h5j]] – mFd + ferredoxin-NADP reductase<br />
		+	**[[5h92]], [[5h8y]] – mFd + sulfite reductase<br />
	**[[3b2g]] – Fd – ''Leptolyngbya boryana''<br />		**[[3b2g]] – Fd – ''Leptolyngbya boryana''<br />
	**[[2mh7]] – Fd – ''Chlamydomonas reinhardtii''<br />		**[[2mh7]] – Fd – ''Chlamydomonas reinhardtii''<br />
	**[[1ewy]] – Fd + ferredoxin-NADP reductase - ''Nostoc''<br />		**[[1ewy]] – Fd + ferredoxin-NADP reductase - ''Nostoc''<br />
		+	**[[5ffi]], [[5abr]] - AvFd – ''Azotobacter vinelandii''<br />
		+	**[[5bok]] - Fd – ''Diaphorobacter''<br />
		+	**[[4zhp]] - Fd – potato<br />
		+	**[[4zho]] – Fd-2 – ''Arabidopsis thaliana''<br />
		+

	*4Fe-4S containing ferredoxins		*4Fe-4S containing ferredoxins
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	**[[1cje]], [[1ayf]] - cADR <br />		**[[1cje]], [[1ayf]] - cADR <br />
	**[[3na0]], [[3n9y]], [[3n9z]], [[3na1]] - hADR +cholesterol side-chain cleavage enzyme – human<br />		**[[3na0]], [[3n9y]], [[3n9z]], [[3na1]] - hADR +cholesterol side-chain cleavage enzyme – human<br />
-	**[[3p1m]] - hADR	+	**[[3p1m]] - hADR<br />
		+	**[[5uj5]] – ADR – ''Encephalitozoon cuniculi''<br />

	*Putidaredoxin		*Putidaredoxin

Michal Harel at 09:03, 2 April 2015

Michal Harel — Thu, 02 Apr 2015 09:03:47 GMT

←Older revision		Revision as of 09:03, 2 April 2015
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	**[[2mjd]], [[2mje]] – yADR – yeast<br />		**[[2mjd]], [[2mje]] – yADR – yeast<br />
-	**[[2jqr]] – ~~ADR~~ Fd domain (mutant)+cytochrome c (mutant) – NMR <br />	+	**[[2jqr]] – yADR Fd domain (mutant)+cytochrome c (mutant) – NMR <br />
	**[[2bt6]] – cADR1 modified – cow <br />		**[[2bt6]] – cADR1 modified – cow <br />
	**[[1l6u]], [[1l6v]] – cADR1 – NMR <br />		**[[1l6u]], [[1l6v]] – cADR1 – NMR <br />

Michal Harel at 09:00, 2 April 2015

Michal Harel — Thu, 02 Apr 2015 09:00:08 GMT

←Older revision		Revision as of 09:00, 2 April 2015
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	**[[2kaj]], [[1dox]], [[1doy]] – SyFd +Ga – ''Synechocystis'' – NMR <br />		**[[2kaj]], [[1dox]], [[1doy]] – SyFd +Ga – ''Synechocystis'' – NMR <br />
-	**[[3hui]] – Fd – ''Rhodopseudomonas palustris'' <br />	+	**[[3hui]], [[4ltu]] – Fd – ''Rhodopseudomonas palustris'' <br />
	**[[1off]] – SyFd <br />		**[[1off]] – SyFd <br />
	**[[3gce]] – Fd – ''Nocardioides aromaticivorans'' <br />		**[[3gce]] – Fd – ''Nocardioides aromaticivorans'' <br />
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	**[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />		**[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />
	**[[3b2f]] – mFd – maize<br />		**[[3b2f]] – mFd – maize<br />
-	**[[3w5u]], [[3w5v]] – mFd + ferredoxin-NADP reductase<br />	+	**[[3w5u]], [[3w5v]], [[1gaq]] – mFd + ferredoxin-NADP reductase<br />
-	**[[3b2g]] – Fd – ''Leptolyngbya boryana''	+	**[[3b2g]] – Fd – ''Leptolyngbya boryana''<br />
		+	**[[2mh7]] – Fd – ''Chlamydomonas reinhardtii''<br />
		+	**[[1ewy]] – Fd + ferredoxin-NADP reductase - ''Nostoc''<br />

	*4Fe-4S containing ferredoxins		*4Fe-4S containing ferredoxins
Line 112:		Line 114:
	*Adrenoredoxin		*Adrenoredoxin

-	**[[2jqr]] – ADR Fd domain (mutant)+cytochrome c (mutant) ~~– yeast~~ – NMR <br />	+	**[[2mjd]], [[2mje]] – yADR – yeast<br />
		+	**[[2jqr]] – ADR Fd domain (mutant)+cytochrome c (mutant) – NMR <br />
	**[[2bt6]] – cADR1 modified – cow <br />		**[[2bt6]] – cADR1 modified – cow <br />
	**[[1l6u]], [[1l6v]] – cADR1 – NMR <br />		**[[1l6u]], [[1l6v]] – cADR1 – NMR <br />

Michal Harel at 07:09, 25 November 2014

Michal Harel — Tue, 25 Nov 2014 07:09:01 GMT

Michal Harel at 08:09, 27 August 2014

Michal Harel — Wed, 27 Aug 2014 08:09:30 GMT

←Older revision		Revision as of 08:09, 27 August 2014
Line 27:		Line 27:
	</StructureSection>		</StructureSection>

-	===3D structures of ferredoxin===	+	==3D structures of ferredoxin==

	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

Michal Harel at 07:01, 24 August 2014

Michal Harel — Sun, 24 Aug 2014 07:01:40 GMT

←Older revision		Revision as of 07:01, 24 August 2014
Line 1:		Line 1:
	<StructureSection load='2z8q' size='450' side='right' scene='' caption='Ferredoxin with Fe4S4 cluster complex with cobalt hexamine (PDB code [[2z8q]])'>		<StructureSection load='2z8q' size='450' side='right' scene='' caption='Ferredoxin with Fe4S4 cluster complex with cobalt hexamine (PDB code [[2z8q]])'>
-	~~[[Image:2z8q.png\|left\|150px]]<br />~~	+

	[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster. It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced. The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters. '''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland. '''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group.		[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster. It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced. The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters. '''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland. '''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group.
Line 125:		Line 125:
	[[1xln]], [[1xlo]], [[1xlp]], [[1xlq]], [[1r7s]], [[1oqq]], [[1oqr]] - PpPUT (mutant) <br />		[[1xln]], [[1xlo]], [[1xlp]], [[1xlq]], [[1r7s]], [[1oqq]], [[1oqr]] - PpPUT (mutant) <br />
	[[1gpx]], [[1put]]- PpPUT (mutant) - NMR <br />		[[1gpx]], [[1put]]- PpPUT (mutant) - NMR <br />
		+	[[4jws]] - PpPUT + cytochrome P450cam<br />
		+	[[3w9c]], [[4jwu]] - PpPUT (mutant) + cytochrome P450cam<br />
		+	[[2m56]] - PpPUT (mutant) + cytochrome P450cam - NMR<br />
		+	[[4jx1]] - PpPUT (mutant) + cytochrome P450cam + camphor + hydroxycamphor<br />

	===Terpredoxin===		===Terpredoxin===

Michal Harel at 08:47, 14 August 2014

Michal Harel — Thu, 14 Aug 2014 08:47:59 GMT

←Older revision		Revision as of 08:47, 14 August 2014
Line 3:		Line 3:

	[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster. It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced. The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters. '''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland. '''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group.		[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster. It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced. The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters. '''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland. '''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group.
-
-	{{TOC limit\|limit=2}}

	==D14C variant of ''Pyrococcus furiosus'' ferredoxin<ref>DOI 10.1007/s00775-011-0778-7</ref>==		==D14C variant of ''Pyrococcus furiosus'' ferredoxin<ref>DOI 10.1007/s00775-011-0778-7</ref>==
Line 28:		Line 26:
	The crystal structure of the <scene name='Journal:JBIC:19/Cv/4'>monomeric form</scene> shows that the <scene name='Journal:JBIC:19/Cv/6'>silver (I) ion is part of the cluster</scene> (clearly seen on the electron density map), as predicted from previous spectroscopic and electrochemical studies. The heterometal is coordinated to the <scene name='Journal:JBIC:19/Cv/5'>three inorganic sulfides of the cluster</scene> and to the <scene name='Journal:JBIC:19/Cv/7'>thiolate group of residue 14</scene> (residues <scene name='Journal:JBIC:19/Cv/8'>Cys11, Cys17 and Cys56</scene> are coordinated with Fe ions of heterometal), <scene name='Journal:JBIC:19/Cv/9'>replacing the aboriginal Fe ion in the all-iron coordinated</scene> [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]], <span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>) and completing the incomplete cuboidal cluster present in the [Fe<sub>3</sub>S<sub>4</sub>] WT Pf Fd (PDB: [[1sj1]]) and its D14C (PDB: [[3pni]]) variant (for more details see also [http://proteopedia.org/w/Journal:JBIC:10 "Crystal structures of the all cysteinyl coordinated D14C variant of ''Pyrococcus furiosus'' ferredoxin: (4Fe-4S) <-> (3Fe-4S) cluster conversion"]). Structure alignment of backbone atoms from the heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein and the homometallic [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]]) shows <scene name='Journal:JBIC:19/Cv/10'>very minor differences</scene>, i.e. the root mean square deviation (RMSD) is 0.4 – 0.7 Å, observed due to the alternate conformation of the main chain atoms, flexible loops and small changes at the N- and C-termini (<span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>). <scene name='Journal:JBIC:19/Cv/14'>More significant difference</scene> can be seen in the superimposed Fe–S clusters (atom colors corresponding to <span style="color:yellow;background-color:black;font-weight:bold;">yellow: S</span>, <span style="color:orange;background-color:black;font-weight:bold;">orange: Fe</span>, <span style="color:gray;background-color:black;font-weight:bold;">gray: Ag</span>) from these two variants, which is due to the presence of the second row transition metal ion (Ag) coordinated to the four S-ligands, i.e. the presence of Ag results in a distorted geometry of the cluster compared to the all-iron arrangement, <scene name='Journal:JBIC:19/Cv/12'>because to the longer</scene> Ag – S bond lengths compared to Fe – S bonds. However, the S – Ag – S <scene name='Journal:JBIC:19/Cv/13'>bond angles</scene> are still close to the expected 90° for a primitive cubic system.		The crystal structure of the <scene name='Journal:JBIC:19/Cv/4'>monomeric form</scene> shows that the <scene name='Journal:JBIC:19/Cv/6'>silver (I) ion is part of the cluster</scene> (clearly seen on the electron density map), as predicted from previous spectroscopic and electrochemical studies. The heterometal is coordinated to the <scene name='Journal:JBIC:19/Cv/5'>three inorganic sulfides of the cluster</scene> and to the <scene name='Journal:JBIC:19/Cv/7'>thiolate group of residue 14</scene> (residues <scene name='Journal:JBIC:19/Cv/8'>Cys11, Cys17 and Cys56</scene> are coordinated with Fe ions of heterometal), <scene name='Journal:JBIC:19/Cv/9'>replacing the aboriginal Fe ion in the all-iron coordinated</scene> [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]], <span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>) and completing the incomplete cuboidal cluster present in the [Fe<sub>3</sub>S<sub>4</sub>] WT Pf Fd (PDB: [[1sj1]]) and its D14C (PDB: [[3pni]]) variant (for more details see also [http://proteopedia.org/w/Journal:JBIC:10 "Crystal structures of the all cysteinyl coordinated D14C variant of ''Pyrococcus furiosus'' ferredoxin: (4Fe-4S) <-> (3Fe-4S) cluster conversion"]). Structure alignment of backbone atoms from the heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein and the homometallic [Fe<sub>4</sub>S<sub>4</sub>] D14C variant ([[2z8q]]) shows <scene name='Journal:JBIC:19/Cv/10'>very minor differences</scene>, i.e. the root mean square deviation (RMSD) is 0.4 – 0.7 Å, observed due to the alternate conformation of the main chain atoms, flexible loops and small changes at the N- and C-termini (<span style="color:cyan;background-color:black;font-weight:bold;">heterometallic [AgFe<sub>3</sub>S<sub>4</sub>] protein is in cyan</span> and <span style="color:lime;background-color:black;font-weight:bold;">homometallic [Fe<sub>4</sub>S<sub>4</sub>] is in green</span>). <scene name='Journal:JBIC:19/Cv/14'>More significant difference</scene> can be seen in the superimposed Fe–S clusters (atom colors corresponding to <span style="color:yellow;background-color:black;font-weight:bold;">yellow: S</span>, <span style="color:orange;background-color:black;font-weight:bold;">orange: Fe</span>, <span style="color:gray;background-color:black;font-weight:bold;">gray: Ag</span>) from these two variants, which is due to the presence of the second row transition metal ion (Ag) coordinated to the four S-ligands, i.e. the presence of Ag results in a distorted geometry of the cluster compared to the all-iron arrangement, <scene name='Journal:JBIC:19/Cv/12'>because to the longer</scene> Ag – S bond lengths compared to Fe – S bonds. However, the S – Ag – S <scene name='Journal:JBIC:19/Cv/13'>bond angles</scene> are still close to the expected 90° for a primitive cubic system.
	</StructureSection>		</StructureSection>
-	~~__NOTOC__~~	+
	===3D structures of ferredoxin===		===3D structures of ferredoxin===

Michal Harel at 10:39, 5 March 2014

Michal Harel — Wed, 05 Mar 2014 10:39:12 GMT

←Older revision		Revision as of 10:39, 5 March 2014
Line 56:		Line 56:
	[[1j7a]], [[1j7b]], [[1j7c]] , [[1qoa]], [[1qob]], [[1qof]], [[1qog]]- aFd (mutant) <br />		[[1j7a]], [[1j7b]], [[1j7c]] , [[1qoa]], [[1qob]], [[1qof]], [[1qog]]- aFd (mutant) <br />
	[[1e0z]] – Fd – ''Halobacterium salinarium'' <br />		[[1e0z]] – Fd – ''Halobacterium salinarium'' <br />
		+	[[1e10]] - Fd – ''Halobacterium halobium''<br />
	[[1pfd]] – Fd – ''Petroselinum crispum'' – NMR <br />		[[1pfd]] – Fd – ''Petroselinum crispum'' – NMR <br />
	[[1a70]] - Fd (mutant) – ''Spinacia oleracea'' <br />		[[1a70]] - Fd (mutant) – ''Spinacia oleracea'' <br />
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	[[3dqy]], [[2qpz]], [[3ah7]] - Fd – ''Pseudomonas putida'' <br />		[[3dqy]], [[2qpz]], [[3ah7]] - Fd – ''Pseudomonas putida'' <br />
	[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />		[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />
-	[[3b2f]] – Fd – maize<br />	+	[[3b2f]] – mFd – maize<br />
		+	[[3w5u]], [[3w5v]] – mFd + ferredoxin-NADP reductase<br />
	[[3b2g]] – Fd – ''Leptolyngbya boryana''		[[3b2g]] – Fd – ''Leptolyngbya boryana''

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	[[1fxr]] - DaFd <br />		[[1fxr]] - DaFd <br />
	[[1vjw]] – Fd – ''Thermotoga maritima'' <br />		[[1vjw]] – Fd – ''Thermotoga maritima'' <br />
		+	[[1dwl]] – Fd – ''Desulfomicrobium norvegicum''<br />

	===3Fe-4S containing ferredoxins===		===3Fe-4S containing ferredoxins===

←Older revision		Revision as of 07:09, 25 November 2014
Line 30:		Line 30:

	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
		+	{{#tree:id=OrganizedByTopic\|openlevels=0\|

-	~~===~~2Fe-2S containing ferredoxins~~===~~	+	*2Fe-2S containing ferredoxins

-	[[2kaj]], [[1dox]], [[1doy]] – SyFd +Ga – ''Synechocystis'' – NMR <br />	+	**[[2kaj]], [[1dox]], [[1doy]] – SyFd +Ga – ''Synechocystis'' – NMR <br />
-	[[3hui]] – Fd – ''Rhodopseudomonas palustris'' <br />	+	**[[3hui]] – Fd – ''Rhodopseudomonas palustris'' <br />
-	[[1off]] – SyFd <br />	+	**[[1off]] – SyFd <br />
-	[[3gce]] – Fd – ''Nocardioides aromaticivorans'' <br />	+	**[[3gce]] – Fd – ''Nocardioides aromaticivorans'' <br />
-	[[3lxf]] – Fd – ''Novosphingobium aromaticivorans''<br />	+	**[[3lxf]] – Fd – ''Novosphingobium aromaticivorans''<br />
-	[[2e4p]], [[2e4q]] - Fd – ''Pseudomonas sp.'' <br />	+	**[[2e4p]], [[2e4q]] - Fd – ''Pseudomonas sp.'' <br />
-	[[2q3w]], [[1vm9]] - PmFd (mutant) – ''Pseudomonas mendocina'' <br />	+	**[[2q3w]], [[1vm9]] - PmFd (mutant) – ''Pseudomonas mendocina'' <br />
-	[[2i7f]], [[1uwm]] - RcFd – ''Rhodobacter capsulatus'' <br />	+	**[[2i7f]], [[1uwm]] - RcFd – ''Rhodobacter capsulatus'' <br />
-	[[1e9m]] – RcFd - NMR<br />	+	**[[1e9m]] – RcFd - NMR<br />
-	[[1rfk]], [[3p63]] - Fd – ''Cyanobacterium'' ''masticogladus laminosus'' <br />	+	**[[1rfk]], [[3p63]] - Fd – ''Cyanobacterium'' ''masticogladus laminosus'' <br />
-	[[1vck]] - Fd – ''Pseudomonas resinovorans'' <br />	+	**[[1vck]] - Fd – ''Pseudomonas resinovorans'' <br />
-	[[1wri]], [[1frr]] - Fd – E''quisetum arvense'' <br />	+	**[[1wri]], [[1frr]] - Fd – E''quisetum arvense'' <br />
-	[[1sjg]] - PmFd– NMR <br />	+	**[[1sjg]] - PmFd– NMR <br />
-	[[1iue]] - Fd– ''Plasmodium falciparum'' <br />	+	**[[1iue]] - Fd– ''Plasmodium falciparum'' <br />
-	[[1m2a]] – AeFd – ''Aquifex aeolicu''s <br />	+	**[[1m2a]] – AeFd – ''Aquifex aeolicu''s <br />
-	[[1m2b]], [[1m2d]], [[1f37]], [[1f5b]], [[1f5c]] – AeFd (mutant) <br />	+	**[[1m2b]], [[1m2d]], [[1f37]], [[1f5b]], [[1f5c]] – AeFd (mutant) <br />
-	[[1l5p]] – Fd – ''Trichomonas vaginali''s <br />	+	**[[1l5p]] – Fd – ''Trichomonas vaginali''s <br />
-	[[1i7h]] - Fd – ''Escherichia coli'' <br />	+	**[[1i7h]] - Fd – ''Escherichia coli'' <br />
-	[[1czp]], [[1qt9]], [[1frd]], [[1fxa]] - aFd– ''anabaena'' <br />	+	**[[1czp]], [[1qt9]], [[1frd]], [[1fxa]] - aFd– ''anabaena'' <br />
-	[[1j7a]], [[1j7b]], [[1j7c]] , [[1qoa]], [[1qob]], [[1qof]], [[1qog]]- aFd (mutant) <br />	+	**[[1j7a]], [[1j7b]], [[1j7c]] , [[1qoa]], [[1qob]], [[1qof]], [[1qog]]- aFd (mutant) <br />
-	[[1e0z]] – Fd – ''Halobacterium salinarium'' <br />	+	**[[1e0z]] – Fd – ''Halobacterium salinarium'' <br />
-	[[1e10]] - Fd – ''Halobacterium halobium''<br />	+	**[[1e10]] - Fd – ''Halobacterium halobium''<br />
-	[[1pfd]] – Fd – ''Petroselinum crispum'' – NMR <br />	+	**[[1pfd]] – Fd – ''Petroselinum crispum'' – NMR <br />
-	[[1a70]] - Fd (mutant) – ''Spinacia oleracea'' <br />	+	**[[1a70]] - Fd (mutant) – ''Spinacia oleracea'' <br />
-	[[1awd]] - Fd – ''Chlorella fusca'' <br />	+	**[[1awd]] - Fd – ''Chlorella fusca'' <br />
-	[[2cjn]], [[2cjo]], [[1roe]] – SyFd – NMR <br />	+	**[[2cjn]], [[2cjo]], [[1roe]] – SyFd – NMR <br />
-	[[1rof]] – SyFd – ''Synechococcus elongates'' <br />	+	**[[1rof]] – SyFd – ''Synechococcus elongates'' <br />
-	[[1doi]] - Fd – ''Haloarcula marismortui'' <br />	+	**[[1doi]] - Fd – ''Haloarcula marismortui'' <br />
-	[[4fxc]] – Fd – ''Spirulina platensi''s <br />	+	**[[4fxc]] – Fd – ''Spirulina platensi''s <br />
-	[[1fxi]], [[3av8]] – Fd – ''Aphanothece sacrum'' <br />	+	**[[1fxi]], [[3av8]] – Fd – ''Aphanothece sacrum'' <br />
-	[[3dqy]], [[2qpz]], [[3ah7]] - Fd – ''Pseudomonas putida'' <br />	+	**[[3dqy]], [[2qpz]], [[3ah7]] - Fd – ''Pseudomonas putida'' <br />
-	[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />	+	**[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />
-	[[3b2f]] – mFd – maize<br />	+	**[[3b2f]] – mFd – maize<br />
-	[[3w5u]], [[3w5v]] – mFd + ferredoxin-NADP reductase<br />	+	**[[3w5u]], [[3w5v]] – mFd + ferredoxin-NADP reductase<br />
-	[[3b2g]] – Fd – ''Leptolyngbya boryana''	+	**[[3b2g]] – Fd – ''Leptolyngbya boryana''

-	~~===~~4Fe-4S containing ferredoxins ~~===~~	+	*4Fe-4S containing ferredoxins

-	[[3eun]] – AvFd – ''Allochromatium vinosum'' <br />	+	**[[3eun]] – AvFd – ''Allochromatium vinosum'' <br />
-	[[3exy]] - AvFd (mutant) <br />	+	**[[3exy]] - AvFd (mutant) <br />
-	[[2vkr]] - Fd+Zn – ''Acidianus ambivalens'' <br />	+	**[[2vkr]] - Fd+Zn – ''Acidianus ambivalens'' <br />
-	[[2z8q]] - PfFd (mutant) – ''Pyrococcus furiosus'' <br />	+	**[[2z8q]] - PfFd (mutant) – ''Pyrococcus furiosus'' <br />
-	[[1siz]] - PfFd<br >	+	**[[1siz]] - PfFd<br >
-	[[3pni]] - PfFd (mutant)<br />	+	**[[3pni]] - PfFd (mutant)<br />
-	[[2fgo]] - Fd– ''Pseudomonas aeruginosa'' <br />	+	**[[2fgo]] - Fd– ''Pseudomonas aeruginosa'' <br />
-	[[1iqz]], [[1ir0]] - BtFd – ''Bacillus thermoproteolyticus'' <br />	+	**[[1iqz]], [[1ir0]] - BtFd – ''Bacillus thermoproteolyticus'' <br />
-	[[1rgv]] - Fd – ''Thauera aromatica'' <br />	+	**[[1rgv]] - Fd – ''Thauera aromatica'' <br />
-	[[1dax]], [[1dfd]] – DaFd – ''Desulfovibrio africanus'' – NMR <br />	+	**[[1dax]], [[1dfd]] – DaFd – ''Desulfovibrio africanus'' – NMR <br />
-	[[1fxr]] - DaFd <br />	+	**[[1fxr]] - DaFd <br />
-	[[1vjw]] – Fd – ''Thermotoga maritima'' <br />	+	**[[1vjw]] – Fd – ''Thermotoga maritima'' <br />
-	[[1dwl]] – Fd – ''Desulfomicrobium norvegicum''<br />	+	**[[1dwl]] – Fd – ''Desulfomicrobium norvegicum''<br />

-	~~===~~3Fe-4S containing ferredoxins~~===~~	+	*3Fe-4S containing ferredoxins

-	[[2v2k]] – Fd – ''Mycobacterium smegmatis'' <br />	+	**[[2v2k]] – Fd – ''Mycobacterium smegmatis'' <br />
-	[[1wtf]] - BtFd (mutant) <br />	+	**[[1wtf]] - BtFd (mutant) <br />
-	[[1sj1]] - PfFd <br />	+	**[[1sj1]] - PfFd <br />
-	[[1fxd]] - DgFd – ''Desulfovibrio gigas'' <br />	+	**[[1fxd]] - DgFd – ''Desulfovibrio gigas'' <br />
-	[[1f2g]] – DgFd – NMR <br />	+	**[[1f2g]] – DgFd – NMR <br />
-	[[1xer]] - Fd – ''Sulfolobus tokodaii'' <br />	+	**[[1xer]] - Fd – ''Sulfolobus tokodaii'' <br />

-	~~===~~4Fe-4S+3Fe-4S containing ferredoxins~~===~~	+	*4Fe-4S+3Fe-4S containing ferredoxins

-	[[1gao]], [[6fdr]], [[7fd1]], [[7fdr]], [[1axq]], [[6fd1]], [[1frh]], [[1fri]],[[1frj]], [[1frk]], [[1frl]], [[1frm]], [[1fda]], [[1fdb]], [[1fdd]], [[5fd1]], [[1fer]] – AvFd – ''Azotobacter vinelandii'' <br />	+	**[[1gao]], [[6fdr]], [[7fd1]], [[7fdr]], [[1axq]], [[6fd1]], [[1frh]], [[1fri]],[[1frj]], [[1frk]], [[1frl]], [[1frm]], [[1fda]], [[1fdb]], [[1fdd]], [[5fd1]], [[1fer]] – AvFd – ''Azotobacter vinelandii'' <br />
-	[[1pc4]], [[1pc5]], [[1g6b]], [[1g3o]], [[1ff2]], [[1b0v]], [[1d3w]], [[1b0t]], [[1a6l]], [[1ftc]], [[1frx]], [[2fd2]], [[1fd2]] - AvFd (mutant) <br />	+	**[[1pc4]], [[1pc5]], [[1g6b]], [[1g3o]], [[1ff2]], [[1b0v]], [[1d3w]], [[1b0t]], [[1a6l]], [[1ftc]], [[1frx]], [[2fd2]], [[1fd2]] - AvFd (mutant) <br />
-	[[1h98]] – Fd – ''Thermus thermophilus'' <br />	+	**[[1h98]] – Fd – ''Thermus thermophilus'' <br />
-	[[1a8p]], [[1bd6]], [[1bc6]] - BsFd – ''Bacillus schlegelii'' – NMR <br />	+	**[[1a8p]], [[1bd6]], [[1bc6]] - BsFd – ''Bacillus schlegelii'' – NMR <br />

-	~~===~~4Fe-4S+4Fe-4S containing ferredoxins~~===~~	+	*4Fe-4S+4Fe-4S containing ferredoxins

-	[[1dur]] – Fd – ''Peptoniphilus asaccarolyticus'' <br />	+	**[[1dur]] – Fd – ''Peptoniphilus asaccarolyticus'' <br />
-	[[1bwe]], [[1bqx]] - BsFd (mutant) – NMR <br />	+	**[[1bwe]], [[1bqx]] - BsFd (mutant) – NMR <br />
-	[[2fdn]], [[1fca]] , [[1fdn]]- Fd – ''Clostridium acidi-urici'' <br />	+	**[[2fdn]], [[1fca]] , [[1fdn]] - Fd – ''Clostridium acidi-urici'' <br />
-	[[1blu]] - Fd – ''Chromatium vinosum'' <br />	+	**[[1blu]] - Fd – ''Chromatium vinosum'' <br />
-	[[1clf ]]– Fd – ''Clostridium pasteurianum'' – NMR <br />	+	**[[1clf]] – Fd – ''Clostridium pasteurianum'' – NMR <br />

-	~~===~~Adrenoredoxin~~===~~	+	*Adrenoredoxin

-	[[2jqr]] – ADR Fd domain (mutant)+cytochrome c (mutant) – yeast – NMR <br />	+	**[[2jqr]] – ADR Fd domain (mutant)+cytochrome c (mutant) – yeast – NMR <br />
-	[[2bt6]] – cADR1 modified – cow <br />	+	**[[2bt6]] – cADR1 modified – cow <br />
-	[[1l6u]], [[1l6v]] – cADR1 – NMR <br />	+	**[[1l6u]], [[1l6v]] – cADR1 – NMR <br />
-	[[1e6e]] – cADR (mutant)+ADR reductase <br />	+	**[[1e6e]] – cADR (mutant)+ADR reductase <br />
-	[[1cje]], [[1ayf]] - cADR <br />	+	**[[1cje]], [[1ayf]] - cADR <br />
-	[[3na0]], [[3n9y]], [[3n9z]], [[3na1]] - hADR +cholesterol side-chain cleavage enzyme – human<br />	+	**[[3na0]], [[3n9y]], [[3n9z]], [[3na1]] - hADR +cholesterol side-chain cleavage enzyme – human<br />
-	[[3p1m]] - hADR	+	**[[3p1m]] - hADR

-	~~===~~Putidaredoxin~~===~~	+	*Putidaredoxin

-	[[1yji]], [[1yjj]], [[1pdx]] – PpPUT – NMR <br />	+	**[[1yji]], [[1yjj]], [[1pdx]] – PpPUT – NMR <br />
-	[[3lb8]] – PpPUT (mutant)+PUT reductase <br />	+	**[[3lb8]] – PpPUT (mutant)+PUT reductase <br />
-	[[1xln]], [[1xlo]], [[1xlp]], [[1xlq]], [[1r7s]], [[1oqq]], [[1oqr]] - PpPUT (mutant) <br />	+	**[[1xln]], [[1xlo]], [[1xlp]], [[1xlq]], [[1r7s]], [[1oqq]], [[1oqr]] - PpPUT (mutant) <br />
-	[[1gpx]], [[1put]]- PpPUT (mutant) - NMR <br />	+	**[[1gpx]], [[1put]]- PpPUT (mutant) - NMR <br />
-	[[4jws]] - PpPUT + cytochrome P450cam<br />	+	**[[4jws]] - PpPUT + cytochrome P450cam<br />
-	[[3w9c]], [[4jwu]] - PpPUT (mutant) + cytochrome P450cam<br />	+	**[[3w9c]], [[4jwu]] - PpPUT (mutant) + cytochrome P450cam<br />
-	[[2m56]] - PpPUT (mutant) + cytochrome P450cam - NMR<br />	+	**[[2m56]] - PpPUT (mutant) + cytochrome P450cam - NMR<br />
-	[[4jx1]] - PpPUT (mutant) + cytochrome P450cam + camphor + hydroxycamphor<br />	+	**[[4jx1]] - PpPUT (mutant) + cytochrome P450cam + camphor + hydroxycamphor<br />

-	~~===~~Terpredoxin~~===~~	+	*Terpredoxin
-		+
-	~~[[1b9r]] – TER – ''Pseudomonas'' - NMR <br />~~	+

		+	**[[1b9r]] – TER – ''Pseudomonas'' - NMR <br />
		+	}}
	==References==		==References==
	<references/>		<references/>