Galactose oxidase - Revision history

Michal Harel at 08:40, 2 August 2021

Michal Harel — Mon, 02 Aug 2021 08:40:01 GMT

←Older revision		Revision as of 08:40, 2 August 2021
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	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

-	[[1gof]], [[1gog]], [[1goh]] – GAO – ''Hypomyces rosellus''<br />	+	[[1gof]], [[1gog]], [[1goh]] – GAO + Cu – ''Hypomyces rosellus''<br />
	[[1k3i]] – FuGAO precursor – ''Fusarium''<br />		[[1k3i]] – FuGAO precursor – ''Fusarium''<br />
-	[[1t2x]] – FuGAO (mutant)<br />	+	[[1t2x]] – FuGAO (mutant) + Cu<br />
-	[[2eib]], [[2eic]], [[2eid]], [[2wq8]] - GzGAO (mutant) – ~~''Gibberella zeae''~~<br />	+	[[2vz3]] - GzGAO + Cu – ''Gibberella zeae''<br />
		+	[[2eib]], [[2eic]], [[2eid]], [[2wq8]] - GzGAO (mutant) + Cu<br />
		+	[[6xlt]] – GzGAO + Cu <br />
		+	[[6xlr]], [[6xls]] – GzGAO + Cu + modified Tyr272<br />
	[[2eie]] – GzGAO + N3<br />		[[2eie]] – GzGAO + N3<br />
-	[[2jkx]] – GzGAO ~~no Cu~~<br />	+	[[2jkx]] – GzGAO <br />
	[[2vz1]] – GzGAO premature<br />		[[2vz1]] – GzGAO premature<br />
-	~~[[2vz3]] - GzGAO~~	+
	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Alexander Berchansky at 13:27, 28 March 2019

Alexander Berchansky — Thu, 28 Mar 2019 13:27:05 GMT

←Older revision		Revision as of 13:27, 28 March 2019
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	== Structural highlights ==		== Structural highlights ==

-	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational <scene name='48/486468/Cv/4'>cross-linking of Cys228 and Tyr272 via a thioester bond</scene> for activity<ref>PMID:2002850</ref>. Water molecules shown as red spheres. <scene name='48/486468/Cv/5'>Na coordination site</scene>.	+	GAO uses <scene name='48/486468/Cv/6'>copper and active site</scene> post-translational <scene name='48/486468/Cv/7'>cross-linking of Cys228 and Tyr272 via a thioester bond</scene> for activity<ref>PMID:2002850</ref>. Water molecules shown as red spheres. <scene name='48/486468/Cv/8'>Na coordination site</scene>.
	</StructureSection>		</StructureSection>
	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==

Alexander Berchansky at 09:14, 6 March 2016

Alexander Berchansky — Sun, 06 Mar 2016 09:14:50 GMT

←Older revision		Revision as of 09:14, 6 March 2016
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	== Structural highlights ==		== Structural highlights ==

-	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational <scene name='48/486468/Cv/4'>cross-linking of Cys228 and Tyr272 via a thioester bond</scene> for activity<ref>PMID:2002850</ref>. Water molecules shown as red spheres.	+	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational <scene name='48/486468/Cv/4'>cross-linking of Cys228 and Tyr272 via a thioester bond</scene> for activity<ref>PMID:2002850</ref>. Water molecules shown as red spheres. <scene name='48/486468/Cv/5'>Na coordination site</scene>.
	</StructureSection>		</StructureSection>
	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==

Alexander Berchansky at 08:30, 6 March 2016

Alexander Berchansky — Sun, 06 Mar 2016 08:30:16 GMT

←Older revision		Revision as of 08:30, 6 March 2016
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	== Structural highlights ==		== Structural highlights ==

-	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational <scene name='48/486468/Cv/4'>cross-linking of Cys228 and Tyr272 via a thioester bond</scene> for activity<ref>PMID:2002850</ref>.	+	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational <scene name='48/486468/Cv/4'>cross-linking of Cys228 and Tyr272 via a thioester bond</scene> for activity<ref>PMID:2002850</ref>. Water molecules shown as red spheres.
	</StructureSection>		</StructureSection>
	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==

Alexander Berchansky at 08:27, 6 March 2016

Alexander Berchansky — Sun, 06 Mar 2016 08:27:11 GMT

←Older revision		Revision as of 08:27, 6 March 2016
Line 7:		Line 7:
	== Structural highlights ==		== Structural highlights ==

-	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational cross-linking of Cys228 and Tyr272 via a thioester bond for activity<ref>PMID:2002850</ref>.	+	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational <scene name='48/486468/Cv/4'>cross-linking of Cys228 and Tyr272 via a thioester bond</scene> for activity<ref>PMID:2002850</ref>.
	</StructureSection>		</StructureSection>
	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==

Alexander Berchansky at 08:22, 6 March 2016

Alexander Berchansky — Sun, 06 Mar 2016 08:22:42 GMT

←Older revision		Revision as of 08:22, 6 March 2016
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	== Structural highlights ==		== Structural highlights ==

-	GAO uses copper and active site post-translational cross-linking of Cys228 and Tyr272 via a thioester bond for activity<ref>PMID:2002850</ref>.	+	GAO uses <scene name='48/486468/Cv/3'>copper and active site</scene> post-translational cross-linking of Cys228 and Tyr272 via a thioester bond for activity<ref>PMID:2002850</ref>.
	</StructureSection>		</StructureSection>
	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==

Alexander Berchansky at 08:15, 6 March 2016

Alexander Berchansky — Sun, 06 Mar 2016 08:15:01 GMT

←Older revision		Revision as of 08:15, 6 March 2016
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-	<StructureSection load='1gog' size='350' side='right' scene='' caption='Galactose oxidase with Cu+2 (orange) and Na+ ions (purple), [[1gog]]'>	+	<StructureSection load='1gog' size='350' side='right' scene='48/486468/Cv/1' caption='Galactose oxidase with Cu+2 (orange) and Na+ ions (purple), [[1gog]]'>

	== Function ==		== Function ==

Alexander Berchansky at 08:13, 6 March 2016

Alexander Berchansky — Sun, 06 Mar 2016 08:13:23 GMT

←Older revision		Revision as of 08:13, 6 March 2016
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-	~~{{STRUCTURE_1gog\| PDB~~=1gog ~~\| SIZE~~=~~400\| SCENE~~= \|right~~\|CAPTION~~=Galactose oxidase with Cu+2 (orange) and Na+ ions (purple), [[1gog]] }}	+	<StructureSection load='1gog' size='350' side='right' scene='' caption='Galactose oxidase with Cu+2 (orange) and Na+ ions (purple), [[1gog]]'>

	== Function ==		== Function ==
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	GAO uses copper and active site post-translational cross-linking of Cys228 and Tyr272 via a thioester bond for activity<ref>PMID:2002850</ref>.		GAO uses copper and active site post-translational cross-linking of Cys228 and Tyr272 via a thioester bond for activity<ref>PMID:2002850</ref>.
-		+	</StructureSection>
	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==

Michal Harel at 09:31, 3 March 2016

Michal Harel — Thu, 03 Mar 2016 09:31:52 GMT

←Older revision		Revision as of 09:31, 3 March 2016
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	== Structural highlights ==		== Structural highlights ==

-	GAO uses copper and active site post-translational cross-linking of Cys228 and Tyr272 via a ~~thioether~~ bond for activity.	+	GAO uses copper and active site post-translational cross-linking of Cys228 and Tyr272 via a thioester bond for activity<ref>PMID:2002850</ref>.

	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==

Michal Harel at 08:17, 3 March 2016

Michal Harel — Thu, 03 Mar 2016 08:17:34 GMT

←Older revision		Revision as of 08:17, 3 March 2016
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	{{STRUCTURE_1gog\| PDB=1gog \| SIZE=400\| SCENE= \|right\|CAPTION=Galactose oxidase with Cu+2 (orange) and Na+ ions (purple), [[1gog]] }}		{{STRUCTURE_1gog\| PDB=1gog \| SIZE=400\| SCENE= \|right\|CAPTION=Galactose oxidase with Cu+2 (orange) and Na+ ions (purple), [[1gog]] }}

-	~~<!--~~	+	== Function ==
-	~~Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page.~~	+
-	~~Or use the four-green-boxes-button to insert scrollable text adjacent~~	+	'''Galactose oxidase''' (GAO) catalyzes the oxidation of D-galactose using O2 to D-galacto-hexodialdose and hydrogen peroxide. GAO catalytic motif is a free radical-coupled copper<ref>PMID:7929198</ref>.
-	~~to a Jmol applet. Check out the other buttons as well!~~	+
-	~~-->~~	+	== Structural highlights ==
-	'''Galactose oxidase''' (GAO) catalyzes the oxidation of D-galactose using O2 to D-galacto-hexodialdose and hydrogen peroxide. GAO uses copper and active site post-translational cross-linking of Cys228 and Tyr272 via a thioether bond for activity. ~~GAO catalytic motif is a free radical-coupled copper.~~	+
		+	GAO uses copper and active site post-translational cross-linking of Cys228 and Tyr272 via a thioether bond for activity.

	==3D structures of galactose oxidase==		==3D structures of galactose oxidase==
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	[[2vz1]] – GzGAO premature<br />		[[2vz1]] – GzGAO premature<br />
	[[2vz3]] - GzGAO		[[2vz3]] - GzGAO
-		+	== References ==
		+	<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]