Heather Kirby-sandbox - Revision history

Karsten Theis at 16:44, 11 January 2018

Karsten Theis — Thu, 11 Jan 2018 16:44:52 GMT

←Older revision		Revision as of 16:44, 11 January 2018
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	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/4'>chain A</scene> or <scene name='61/611452/Chainb/2'>chain B</scene>.		The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/4'>chain A</scene> or <scene name='61/611452/Chainb/2'>chain B</scene>.

-	Here is a rendition of<scene name='61/611452/A_surf_b_cartoon/1'> chain A as surface with chain B as ribbon</scene>.	+	Here is a rendition of<scene name='61/611452/A_surf_b_cartoon/1'> chain A as surface with chain B as ribbon</scene> and <scene name='61/611452/Chainb/3'>chain B as surface with chain A as ribbon</scene>.

	<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.		<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.

Karsten Theis at 16:35, 11 January 2018

Karsten Theis — Thu, 11 Jan 2018 16:35:27 GMT

←Older revision		Revision as of 16:35, 11 January 2018
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	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/4'>chain A</scene> or <scene name='61/611452/Chainb/2'>chain B</scene>.		The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/4'>chain A</scene> or <scene name='61/611452/Chainb/2'>chain B</scene>.
		+
		+	Here is a rendition of<scene name='61/611452/A_surf_b_cartoon/1'> chain A as surface with chain B as ribbon</scene>.

	<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.		<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.

Karsten Theis at 16:23, 11 January 2018

Karsten Theis — Thu, 11 Jan 2018 16:23:32 GMT

←Older revision		Revision as of 16:23, 11 January 2018
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	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.		The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.

-	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/3'>chain A</scene> or <scene name='61/611452/Chainb/2'>chain B</scene>.	+	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/4'>chain A</scene> or <scene name='61/611452/Chainb/2'>chain B</scene>.

	<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.		<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.

Karsten Theis at 16:18, 11 January 2018

Karsten Theis — Thu, 11 Jan 2018 16:18:51 GMT

←Older revision		Revision as of 16:18, 11 January 2018
Line 12:		Line 12:
	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.		The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.

-	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/3'>chain A</scene> or <scene name='61/611452/Chainb/1'>chain B</scene>.	+	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/3'>chain A</scene> or <scene name='61/611452/Chainb/2'>chain B</scene>.

	<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.		<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.

Karsten Theis at 16:13, 11 January 2018

Karsten Theis — Thu, 11 Jan 2018 16:13:14 GMT

←Older revision		Revision as of 16:13, 11 January 2018
Line 12:		Line 12:
	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.		The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.

-	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/1'>chain A</scene> or <scene name='61/611452/Chainb/1'>chain B</scene>.	+	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/3'>chain A</scene> or <scene name='61/611452/Chainb/1'>chain B</scene>.

	<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.		<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.

Karsten Theis at 16:03, 11 January 2018

Karsten Theis — Thu, 11 Jan 2018 16:03:12 GMT

←Older revision		Revision as of 16:03, 11 January 2018
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	Insulin is a hormone which is responsible for carbohydrate metabolism and storage. The body senses the concentration of glucose in the blood and responds by secreting insulin. Insulin is produced by beta cells in the pancreas.		Insulin is a hormone which is responsible for carbohydrate metabolism and storage. The body senses the concentration of glucose in the blood and responds by secreting insulin. Insulin is produced by beta cells in the pancreas.

-	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.	+	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.
		+
		+	The physical model shows the two chains separately as molecular surfaces, with black dots showing the approximate location of the sulfur atoms of Cys A7 and B7, and the red dots showing the sulfur atoms of Cys A20 and B19. To see a similar representation in the browser, click on <scene name='61/611452/Chaina/1'>chain A</scene> or <scene name='61/611452/Chainb/1'>chain B</scene>.

	<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.		<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.

Karsten Theis at 17:47, 26 March 2015

Karsten Theis — Thu, 26 Mar 2015 17:47:58 GMT

←Older revision		Revision as of 17:47, 26 March 2015
Line 6:		Line 6:

	<scene name='61/611452/All_atom/8'>Cysteine on chain B</scene>		<scene name='61/611452/All_atom/8'>Cysteine on chain B</scene>
-	~~<scene name='61/611452/Proinsulin/1'>Proinsulin</scene>~~	+

	Insulin is a hormone which is responsible for carbohydrate metabolism and storage. The body senses the concentration of glucose in the blood and responds by secreting insulin. Insulin is produced by beta cells in the pancreas.		Insulin is a hormone which is responsible for carbohydrate metabolism and storage. The body senses the concentration of glucose in the blood and responds by secreting insulin. Insulin is produced by beta cells in the pancreas.
Line 12:		Line 12:
	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.		The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.

-	Proinsulin is the precursor of insulin. It is produced by the pancreas and then converted into insulin. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.	+	<scene name='61/611452/Proinsulin/2'>Proinsulin</scene> is the precursor of insulin. It is produced by the pancreas and then converted into <scene name='61/611452/All_atom/12'>insulin</scene>. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.

Heather Kirby at 15:37, 10 December 2014

Heather Kirby — Wed, 10 Dec 2014 15:37:34 GMT

←Older revision		Revision as of 15:37, 10 December 2014
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	[[Media:Insulin.MOV]]==Insulin Molecule==		[[Media:Insulin.MOV]]==Insulin Molecule==

-		+	<StructureSection load='4ins' size='340' side='right' caption='Caption for this structure' scene=''>
	<scene name='61/611452/All_atom/1'>Insulin,chains A(blue) and B(green)</scene>		<scene name='61/611452/All_atom/1'>Insulin,chains A(blue) and B(green)</scene>
	<scene name='61/611452/All_atom/10'>Cysteine on chain A</scene>		<scene name='61/611452/All_atom/10'>Cysteine on chain A</scene>

Heather Kirby at 15:35, 10 December 2014

Heather Kirby — Wed, 10 Dec 2014 15:35:13 GMT

←Older revision		Revision as of 15:35, 10 December 2014
Line 1:		Line 1:
	[[Media:Insulin.MOV]]==Insulin Molecule==		[[Media:Insulin.MOV]]==Insulin Molecule==
-	~~<StructureSection load='4ins' size='340' side='right' caption='Caption for this structure' scene=''>~~	+
-	~~This is a default text for your page '''Heather Kirby-sandbox'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs.~~	+
-	~~You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.~~	+

	<scene name='61/611452/All_atom/1'>Insulin,chains A(blue) and B(green)</scene>		<scene name='61/611452/All_atom/1'>Insulin,chains A(blue) and B(green)</scene>
Line 14:		Line 12:
	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.		The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.

-	Proinsulin is the precursor of insulin. It is produced by the pancreas and then converted into insulin. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.	+	Proinsulin is the precursor of insulin. It is produced by the pancreas and then converted into insulin. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.
-		+
-		+
-	~~[[Image:Example.jpg]]~~	+

Heather Kirby at 15:34, 10 December 2014

Heather Kirby — Wed, 10 Dec 2014 15:34:03 GMT

←Older revision		Revision as of 15:34, 10 December 2014
Line 1:		Line 1:
-	[[Media:Insulin.MOV]]==Insulin Molecule==	+	[[Media:Insulin.MOV]]==Insulin Molecule==
	<StructureSection load='4ins' size='340' side='right' caption='Caption for this structure' scene=''>		<StructureSection load='4ins' size='340' side='right' caption='Caption for this structure' scene=''>
	This is a default text for your page '''Heather Kirby-sandbox'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs.		This is a default text for your page '''Heather Kirby-sandbox'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs.
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	<scene name='61/611452/Proinsulin/1'>Proinsulin</scene>		<scene name='61/611452/Proinsulin/1'>Proinsulin</scene>

-	~~== Function ==~~	+	Insulin is a hormone which is responsible for carbohydrate metabolism and storage. The body senses the concentration of glucose in the blood and responds by secreting insulin. Insulin is produced by beta cells in the pancreas.

-	~~== Disease ==~~	+	The two chains shown, A and B, are the two pieces that make up insulin. These chains are joined by two disulfide bonds. The location of these bonds are represented by the labeled cysteine molecules on chains A and B. This is the active form of insulin. This form binds to muscle or fat cells to signal them to take up glucose, or sugar from the blood for storage.

-	~~== Relevance ==~~	+	Proinsulin is the precursor of insulin. It is produced by the pancreas and then converted into insulin. It can bind to the insulin receptor and exhibits 5% to 10% of the metabolic activity of insulin. A high concentration of proinsulin in the blood can be a warning sign of islet cell tumors.
		+

-	~~== Structural highlights ==~~	+	[[Image:Example.jpg]]
-		+
-	This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. ~~You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.~~	+
-		+
-	~~</StructureSection>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+