Hemagglutinin - Revision history

Mark Hoelzer at 19:09, 31 July 2019

Mark Hoelzer — Wed, 31 Jul 2019 19:09:09 GMT

←Older revision		Revision as of 19:09, 31 July 2019
Line 72:		Line 72:
	==3D structures of hemagglutinin==		==3D structures of hemagglutinin==
	[[Hemagglutinin 3D structures]]		[[Hemagglutinin 3D structures]]
		+
		+	==3D Printed Physical Models of Hemagglutinin==
		+
		+	Shown below are 3D printed physical models of Hemagglutinin. The model is shown as an alpha carbon backbone, with key sidechains and domains highlighted. It has been designed with precisely embedded magnets that allow the three chains to pull apart into individual pieces.
		+
		+
		+	[[Image:hemagglutinin_1_centerForBiomolecularModeling.jpg \| 450px]][[Image:hemagglutinin_2_centerForBiomolecularModeling.jpg \| 450px]]
		+
		+	====The MSOE Center for BioMolecular Modeling====
		+
		+	[[Image:CbmUniversityLogo.jpg \| left \| 100px]]
		+
		+	The [http://cbm.msoe.edu MSOE Center for BioMolecular Modeling] uses 3D printing technology to create physical models of protein and molecular structures, making the invisible molecular world more tangible and comprehensible. To view more protein structure models, visit our [http://cbm.msoe.edu/educationalmedia/modelgallery/ Model Gallery].

	</StructureSection>		</StructureSection>

Michal Harel at 08:18, 24 July 2019

Michal Harel — Wed, 24 Jul 2019 08:18:25 GMT

←Older revision		Revision as of 08:18, 24 July 2019
Line 74:		Line 74:

	</StructureSection>		</StructureSection>
-
-	==3D structures of hemagglutinin==
-
-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*Various hemagglutinin
-
-	**[[3aj5]], [[3ah1]], [[3ah2]], [[3ah4]] – CbHA1 + glucoside - ''Clostridium botulinum''<br />
-	**[[1qxm]] - CbHA1 (mutant)<br />
-	**[[3aj6]] - CbHA1 (mutant) + glucoside<br />
-	**[[2zoe]], [[2zs6]], [[4en6]], [[4en7]], [[4en8]], [[4en9]] – CbHA3 + glucoside<br />
-	**[[2e4m]] – CbHA1 + HA17<br />
-	**[[4ouj]] – CbHA33 (mutant)<br />
-	**[[4qd2]] – CbHA33 + HA17 + HA70 + cadherin<br />
-	**[[3win]] – CbHA1 + HA2 + HA3 <br />
-	**[[3a5p]] – HA I – slime mold<br />
-	**[[4fbr]] – MxHA – ''Myxococcus xanthus''<br />
-	**[[4fbv]] - MxHA + glucoside<br />
-	**[[6d7y]] – HA + immune protein – ''Pseudomonas aeruginosa''<br />
-
-	*Influenza hemagglutinin (IvHA)
-
-	**[[2jrd]], [[1ibn]], [[1ibo]] – IvHA fusion domain – NMR<br />
-	**[[2dci]], [[1xoo]], [[1xop]] - IvHA fusion domain (mutant) – NMR<br />
-	**[[6chx]] - IvHA head domain<br />
-	**[[2ibx]], [[1ti8]], [[2wr0]], [[2wr1]], [[2wr2]], [[2wr3]], [[2wr4]], [[2wr5]], [[2wr7]], [[2wrb]], [[2wrc]], [[2wrd]], [[2wre]], [[2wrf]], [[2wrg]], [[2wrh]], [[3uyw]], [[4wa1]], [[4we8]], [[4wea]], [[4wsr]], [[6d8w]], [[6osr]], [[6ona]], [[6n41]], [[6n08]], [[6mzk]], [[6mym]], [[6mya]], [[6mxu]], [[5ykc]] – IvHA<br />
-	**[[5z88]], [[5yt9]], [[5yt8]] - IvHA (mutant)<br />
-	**[[4we9]], [[4wss]] - IvHA + sialic acid derivative<br />
-	**[[4f23]] - IvHA precursor<br />
-	**[[1ha0]] – IvHA precursor (mutant) <br />
-	**[[3whe]], [[4lvh]], [[6n5e]], [[6n5d]], [[6n5b]], [[6iuv]], [[6iut]], [[6e56]], [[6e4x]], [[6d0u]], [[6a4k]], [[6a67]], [[6a0z]] - IvHA + antibody<br />
-	**[[6cnv]] - IvHA + envelope glycoprotein + SD84H + antibody<br />
-
-	*''IvHA subunit HA1''
-
-	**[[4we6]], [[4we7]], [[5xl2]] – IvHA1<br />
-	**[[3qqi]], [[3mlh]] - IvHA1 receptor-binding domain <br />
-	**[[2yp2]], [[2yp3]], [[2yp4]], [[2yp5]], [[2yp7]], [[2yp8]], [[2yp9]], [[3uyx]], [[4fiu]], [[5xl8]] - IvHA1 (mutant)<br />
-	**[[5xla]], [[5xl9]] - IvHA1 (mutant) + sialic acid derivative<br />
-	**[[2vis]], [[2vit]] - IvHA1 (mutant) + antibody<br />
-	**[[4fqj]], [[4hkx]], [[4fp8]], [[4m5z]], [[5xhv]], [[5w0d]], [[5w08]], [[5vag]] - IvHA1 + antibody<br />
-
-	*''IvHA subunit HA2''
-
-	**[[1qu1]], [[4nkj]] – IvHA2<br />
-	**[[4p67]], [[4s1x]] – IvHA2 (mutant) <br />
-	**[[4oxm]] – IvHA2 coiled coil<br />
-
-	*''IvHA subunit HA1+HA2''
-
-	**[[3m5g]], [[3al4]], [[3lzg]], [[3m6s]], [[3ku3]], [[3ku5]], [[3hto]], [[3eyj]], [[3bt6]], [[1ru7]], [[1ruy]], [[1ruz]], [[1rd8]], [[1mql]], [[1htm]], [[2hmg]], [[3hmg]], [[4hmg]], [[5hmg]], [[1jsd]], [[1jsm]], [[3s11]], [[3s12]], [[3s13]], [[2ypg]], [[4dj6]], [[4dj7]], [[4dj8]], [[4bgw]], [[4bgz]], [[4bh2]], [[4bsa]], [[4bsg]], [[4eda]], [[4edb]], [[4h32]], [[4k62]], [[4k63]], [[4kdq]], [[4kpq]], [[4kps]], [[4fnk]], [[4fqm]], [[4k3x]], [[4kol]], [[4kth]], [[4lcx]], [[4ln3]], [[4ln6]], [[4lxv]], [[4m40]], [[4mc5]], [[4mhi]], [[4n5j]], [[4n5k]], [[4cyv]], [[4juk]], [[4jul]], [[4jum]], [[4jun]], [[4kw1]], [[4kwm]], [[4o5n]], [[4qy0]], [[4uo0]], [[4uo4]], [[4w8n]], [[4we4]], [[4we5]], [[4wst]], [[4wsw]], [[4wsx]], [[4xkd]], [[4xq5]], [[5vjk]], [[5tg8]], [[5huf]], [[5hu8]], [[5dut]], [[5bny]], [[4unz]], [[4uny]], [[4unx]], [[4unw]], [[4d00]], [[6d7u]], [[6d8b]], [[6d8d]], [[6d7c]], [[6bkp]], [[6aor]], [[6aoq]], [[5xl1]], [[6nsb]], [[6nsa]], [[6ns9]], [[6n5a]], [[6n4f]], [[5xrt]], [[5xrs]] - IvHA1 + HA2<br />
-	**[[6hjn]], [[6hjr]] - IvHA1 + HA2 – Cryo EM<br />
-	**[[4cqp]], [[4cqq]], [[4cqr]], [[4cqs]], [[4cqu]], [[4cqv]], [[4cr0]], [[4uo3]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]], [[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[5thb]], [[5th0]], [[5tgo]], [[4zcj]], [[6bko]], [[6bkn]], [[6bkm]], [[6aop]], [[5xlb]], [[5xl5]], [[5vtz]], [[5vtx]], [[5vtu]], [[6nsg]], [[6nsf]], [[6nsc]], [[6e7h]], [[6e7g]] - IvHA1 (mutant) + HA2<br />
-	**[[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]] - IvHA1 (mutant) + HA2<br />
-	**[[2viu]], [[3vun]], [[5thf]] - IvHA1 (mutant) + HA2 (mutant) <br />
-	**[[4i78]], [[4m4y]], [[3qqb]], [[3qqe]], [[3qqo]] - IvHA1 + HA2 (mutant)<br />
-	**[[1jsh]], [[1jsi]], [[1jsn]], [[1jso]], [[4bgx]], [[4bgy]], [[4bh0]], [[4bh1]], [[4bh3]], [[4bh4]], [[4bsb]], [[4bsc]], [[4bsd]], [[4bsh]], [[4bsi]], [[4jtv]], [[4k64]], [[3znk]], [[3znl]], [[3znm]], [[3zp0]], [[3zp1]], [[4ln4]], [[4ln8]], [[4m44]], [[4bse]], [[4bsf]], [[4cyw]], [[4cyz]], [[4cz0]], [[4n62]], [[4qy1]], [[4qy2]], [[4uo1]], [[4uo2]], [[4uo5]], [[4uo6]], [[4uo7]], [[4uo8]], [[4uoa]], [[4wa2]], [[4wsu]], [[4wsv]], [[4xke]], [[4xkf]], [[4xkg]], [[4xqo]], [[4xqu]], [[5ajm]], [[5tg9]], [[5br6]], [[5br3]], [[5br0]], [[5bqz]], [[5bqy]], [[4yyb]], [[4yya]], [[4yy9]], [[4yy7]], [[4yy1]], [[4yy0]], [[6bkt]], [[6aov]], [[6aou]], [[6aot]], [[6aos]], [[5xl4]], [[5xl3]] - IvHA1 + HA2 + sialic acid derivative<br />
-	**[[6cf5]], [[6ce6]] - IvHA1 + HA2 + taurine derivative<br />
-	**[[3ubj]], [[3ube]], [[3ubn]], [[3ubq]], [[4k66]], [[4k67]], [[4kdn]], [[4kdo]], [[3zp3]], [[3zp2]], [[3zp6]], [[3zpb]], [[4cqw]], [[4cqx]], [[4cqy]], [[4cqz]], [[4uo9]], [[5vjm]], [[5vjl]], [[5thc]], [[5th1]], [[5tgv]], [[5tgu]], [[5e35]], [[5e34]], [[5e32]], [[5e30]], [[5e2z]], [[5e2y]], [[6bks]], [[6bkr]], [[6bkq]], [[5xld]], [[5xlc]], [[5xl7]], [[5xl6]], [[5vu4]], [[5vty]], [[5vtw]], [[5vtr]], [[5vtq]], [[5vmj]], [[5vmg]], [[5vmf]], [[5vmc]], [[5t0e]], [[5t0d]], [[5t0b]], [[5t08]] - IvHA1 (mutant) + HA2 + sialic acid derivative<br />
-	**[[5vtv]] - IvHA1 + HA2 (mutant) + sialic acid derivative<br />
-	**[[3htp]], [[3htq]], [[3htt]], [[2rft]], [[2rfu]], [[1rv0]], [[1rvt]], [[1rvx]], [[1rvz]], [[1mqm]], [[1mqn]], [[1hgd]], [[1hge]], [[1hgf]], [[1hgg]], [[1hgh]], [[1hgi]], [[1hgj]], [[3m5h]], [[3m5i]], [[3m5j]], [[4kom]], [[4kon]], [[4lkg]], [[4lkh]], [[4lki]], [[4lkj]], [[4lkk]], [[4n60]], [[4n61]] [[4n62]], [[4n63]], [[4n64]] - IvHA1 + HA2 + polysaccharide<br />
-	**[[3eyk]], [[3eym]], [[6cfg]], [[6cf7]], [[6cex]] - IvHA1 + HA2 + membrane-fusion inhibitor<br />
-	**[[4eef]] - IvHA1 + HA2 + HA-binding protein<br />
-	**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />
-	**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />
-	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]], [[6b3m]], [[5wko]], [[5w6g]], [[5ug0]], [[6nz7]], [[6ml8]], [[6ii9]], [[6ii8]], [[6ii4]], [[6fyw]], [[6fyu]], [[6fyt]], [[6e3h]], [[5y2m]], [[5y2l]], [[5xku]], [[5w42]] - IvHA1 + HA2 + antibody<br />
-	**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />
-	**[[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]], [[6mlm]], [[6hjp]], [[6hjq]] - IvHA1 + HA2 + antibody – Cryo EM<br />
-	**[[5w6u]], [[5w6t]], [[5w6r]], [[5w6i]], [[5w5u]], [[5w5s]], [[5vli]] - IvHA1 + HA2 + peptide<br />
-	**[[5kuy]] - IvHA1 + HA2 (mutant) + polypeptide inhibitor<br />
-
-	*Viral hemagglutinin-neuraminidase
-
-	**[[1usx]], [[4fzh]], [[3t1e]] – NvHN head domain + thiosialoside – Newcastle disease virus<br />
-	**[[1usr]], [[1e8t]], [[1e8u]], [[1e8v]], [[4fzh]] - NvHN head domain<br />
-	**[[3t1e]] - NvHN ectodomain<br />
-	**[[1v2i]], [[1v3b]] – hpvHN 3 – Human parainfluenza virus<br />
-	**[[4mze]] – hpvPIV 3 (mutant) <br />
-	**[[1v3c]], [[1v3d]], [[1v3e]], [[4wef]], [[4xjq]], [[4xjr]], [[4mza]], [[6c0m]] – hpvHN 3 + glucoside<br />
-	**[[4jf7]] - hpv 5 + glucoside<br />
-	**[[5kv8]], [[5kv9]] – hPIV + inhibitor <br />
-	**[[4mze]] - hpvHN 3 (mutant) + glucoside<br />
-	**[[3tsi]] – hpvHN 5 stalk domain<br />
-	**[[1z4v]], [[1z4w]], [[1z4z]], [[1z50]] – SvHN extracellular domain + DANA – Simian virus<br />
-	**[[1z4x]], [[1z4y]] - SvHN extracellular domain + glucoside<br />
-	**[[4jf7]] - SvHN extracellular domain<br />
-	**[[2vsk]], [[2vsm]] – HN ephrin-binding domain + ephrin – Hendra virus<br />
-	**[[2vwd]], [[3d11]] - NivHN receptor-binding domain – Nipah virus<br />
-	**[[3d12]] - NivHN receptor-binding domain + ephrin<br />
-	**[[5b2c]] - MvHN - Mumps virus<br />
-	**[[5b2d]] - MvHN + sialyllactose<br />
-	**[[gjjn]], [[6jjm]] – HN – mumps rubulavirus<br />
-
-	*Measles virus hemagglutinin
-
-	**[[2rkc]] – MvHA extracellular domain – Measles virus<br />
-	**[[2zb5]], [[2zb6]] - MvHA head domain<br />
-	**[[3alw]], [[3alx]], [[3alz]] – MvHA/SLAM receptor <br />
-	**[[3inb]] – MvHA head domain + hMembrane cofactor protein<br />
-	**[[1rwr]] – HA filamentous – Bordetella pertussis
-
-	*Dr hemagglutinin
-
-	**[[2w5p]] – EcDrae adhesin subunit – ''Escherichia coli''<br />
-	**[[1ut1]] - EcDrae adhesin subunit (mutant) <br />
-	**[[2jkj]], [[2jkl]], [[2jkn]], [[1usq]] - EcDrae adhesin subunit + chloramphenicol derivative
-
-	*Phytohemagglutinin
-
-	**[[1g8w]], [[1fat]], [[3wcr]] – kbPHA-L – kidney bean<br />
-	**[[3wcs]] – kbPHA-L + galactose<br />
-
-	*Various viral hemagglutinin
-
-	**[[1kke]] – RvSigma1 – human orthoreovirus<br />
-	**[[3eoy]] – RvSigma1 + junctional adhesion molecule<br />
-	**[[2aen]] – VP8 – human rotavirus
-	}}
-
-
-
-
-
-
-
-
-

	==Additional Resources==		==Additional Resources==

Michal Harel at 08:17, 24 July 2019

Michal Harel — Wed, 24 Jul 2019 08:17:00 GMT

←Older revision		Revision as of 08:17, 24 July 2019
Line 69:		Line 69:

	(**) The amino acid 153 lacks for the A monomer chain.		(**) The amino acid 153 lacks for the A monomer chain.
		+
		+	==3D structures of hemagglutinin==
		+	[[Hemagglutinin 3D structures]]
		+
	</StructureSection>		</StructureSection>

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	**[[3a5p]] – HA I – slime mold<br />		**[[3a5p]] – HA I – slime mold<br />
	**[[4fbr]] – MxHA – ''Myxococcus xanthus''<br />		**[[4fbr]] – MxHA – ''Myxococcus xanthus''<br />
-	**[[4fbv]] - MxHA + glucoside	+	**[[4fbv]] - MxHA + glucoside<br />
		+	**[[6d7y]] – HA + immune protein – ''Pseudomonas aeruginosa''<br />

	*Influenza hemagglutinin (IvHA)		*Influenza hemagglutinin (IvHA)
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	**[[2jrd]], [[1ibn]], [[1ibo]] – IvHA fusion domain – NMR<br />		**[[2jrd]], [[1ibn]], [[1ibo]] – IvHA fusion domain – NMR<br />
	**[[2dci]], [[1xoo]], [[1xop]] - IvHA fusion domain (mutant) – NMR<br />		**[[2dci]], [[1xoo]], [[1xop]] - IvHA fusion domain (mutant) – NMR<br />
-	**[[2ibx]], [[1ti8]], [[2wr0]], [[2wr1]], [[2wr2]], [[2wr3]], [[2wr4]], [[2wr5]], [[2wr7]], [[2wrb]], [[2wrc]], [[2wrd]], [[2wre]], [[2wrf]], [[2wrg]], [[2wrh]], [[3uyw]], [[4wa1]], [[4we8]], [[4wea]], [[4wsr]], [[6d8w]] – IvHA<br />	+	**[[6chx]] - IvHA head domain<br />
		+	**[[2ibx]], [[1ti8]], [[2wr0]], [[2wr1]], [[2wr2]], [[2wr3]], [[2wr4]], [[2wr5]], [[2wr7]], [[2wrb]], [[2wrc]], [[2wrd]], [[2wre]], [[2wrf]], [[2wrg]], [[2wrh]], [[3uyw]], [[4wa1]], [[4we8]], [[4wea]], [[4wsr]], [[6d8w]], [[6osr]], [[6ona]], [[6n41]], [[6n08]], [[6mzk]], [[6mym]], [[6mya]], [[6mxu]], [[5ykc]] – IvHA<br />
		+	**[[5z88]], [[5yt9]], [[5yt8]] - IvHA (mutant)<br />
	**[[4we9]], [[4wss]] - IvHA + sialic acid derivative<br />		**[[4we9]], [[4wss]] - IvHA + sialic acid derivative<br />
	**[[4f23]] - IvHA precursor<br />		**[[4f23]] - IvHA precursor<br />
	**[[1ha0]] – IvHA precursor (mutant) <br />		**[[1ha0]] – IvHA precursor (mutant) <br />
-	**[[3whe]], [[4lvh]] - IvHA + antibody<br />	+	**[[3whe]], [[4lvh]], [[6n5e]], [[6n5d]], [[6n5b]], [[6iuv]], [[6iut]], [[6e56]], [[6e4x]], [[6d0u]], [[6a4k]], [[6a67]], [[6a0z]] - IvHA + antibody<br />
		+	**[[6cnv]] - IvHA + envelope glycoprotein + SD84H + antibody<br />

	*''IvHA subunit HA1''		*''IvHA subunit HA1''
Line 117:		Line 125:
	*''IvHA subunit HA1+HA2''		*''IvHA subunit HA1+HA2''

-	**[[3m5g]], [[3al4]], [[3lzg]], [[3m6s]], [[3ku3]], [[3ku5]], [[3hto]], [[3eyj]], [[3bt6]], [[1ru7]], [[1ruy]], [[1ruz]], [[1rd8]], [[1mql]], [[1htm]], [[2hmg]], [[3hmg]], [[4hmg]], [[5hmg]], [[1jsd]], [[1jsm]], [[3s11]], [[3s12]], [[3s13]], [[2ypg]], [[4dj6]], [[4dj7]], [[4dj8]], [[4bgw]], [[4bgz]], [[4bh2]], [[4bsa]], [[4bsg]], [[4eda]], [[4edb]], [[4h32]], [[4k62]], [[4k63]], [[4kdq]], [[4kpq]], [[4kps]], [[4fnk]], [[4fqm]], [[4k3x]], [[4kol]], [[4kth]], [[4lcx]], [[4ln3]], [[4ln6]], [[4lxv]], [[4m40]], [[4mc5]], [[4mhi]], [[4n5j]], [[4n5k]], [[4cyv]], [[4juk]], [[4jul]], [[4jum]], [[4jun]], [[4kw1]], [[4kwm]], [[4o5n]], [[4qy0]], [[4uo0]], [[4uo4]], [[4w8n]], [[4we4]], [[4we5]], [[4wst]], [[4wsw]], [[4wsx]], [[4xkd]], [[4xq5]], [[5vjk]], [[5tg8]], [[5huf]], [[5hu8]], [[5dut]], [[5bny]], [[4unz]], [[4uny]], [[4unx]], [[4unw]], [[4d00]], [[6d7u]], [[6d8b]], [[6d8d]], [[6d7c]], [[6bkp]], [[6aor]], [[6aoq]], [[5xl1]] - IvHA1 + HA2<br />	+	**[[3m5g]], [[3al4]], [[3lzg]], [[3m6s]], [[3ku3]], [[3ku5]], [[3hto]], [[3eyj]], [[3bt6]], [[1ru7]], [[1ruy]], [[1ruz]], [[1rd8]], [[1mql]], [[1htm]], [[2hmg]], [[3hmg]], [[4hmg]], [[5hmg]], [[1jsd]], [[1jsm]], [[3s11]], [[3s12]], [[3s13]], [[2ypg]], [[4dj6]], [[4dj7]], [[4dj8]], [[4bgw]], [[4bgz]], [[4bh2]], [[4bsa]], [[4bsg]], [[4eda]], [[4edb]], [[4h32]], [[4k62]], [[4k63]], [[4kdq]], [[4kpq]], [[4kps]], [[4fnk]], [[4fqm]], [[4k3x]], [[4kol]], [[4kth]], [[4lcx]], [[4ln3]], [[4ln6]], [[4lxv]], [[4m40]], [[4mc5]], [[4mhi]], [[4n5j]], [[4n5k]], [[4cyv]], [[4juk]], [[4jul]], [[4jum]], [[4jun]], [[4kw1]], [[4kwm]], [[4o5n]], [[4qy0]], [[4uo0]], [[4uo4]], [[4w8n]], [[4we4]], [[4we5]], [[4wst]], [[4wsw]], [[4wsx]], [[4xkd]], [[4xq5]], [[5vjk]], [[5tg8]], [[5huf]], [[5hu8]], [[5dut]], [[5bny]], [[4unz]], [[4uny]], [[4unx]], [[4unw]], [[4d00]], [[6d7u]], [[6d8b]], [[6d8d]], [[6d7c]], [[6bkp]], [[6aor]], [[6aoq]], [[5xl1]], [[6nsb]], [[6nsa]], [[6ns9]], [[6n5a]], [[6n4f]], [[5xrt]], [[5xrs]] - IvHA1 + HA2<br />
-	**[[4cqp]], [[4cqq]], [[4cqr]], [[4cqs]], [[4cqu]], [[4cqv]], [[4cr0]], [[4uo3]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]], [[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[5thb]], [[5th0]], [[5tgo]], [[4zcj]], [[6bko]], [[6bkn]], [[6bkm]], [[6aop]], [[5xlb]], [[5xl5]], [[5vtz]], [[5vtx]], [[5vtu]] - IvHA1 (mutant) + HA2<br />	+	**[[6hjn]], [[6hjr]] - IvHA1 + HA2 – Cryo EM<br />
		+	**[[4cqp]], [[4cqq]], [[4cqr]], [[4cqs]], [[4cqu]], [[4cqv]], [[4cr0]], [[4uo3]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]], [[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[5thb]], [[5th0]], [[5tgo]], [[4zcj]], [[6bko]], [[6bkn]], [[6bkm]], [[6aop]], [[5xlb]], [[5xl5]], [[5vtz]], [[5vtx]], [[5vtu]], [[6nsg]], [[6nsf]], [[6nsc]], [[6e7h]], [[6e7g]] - IvHA1 (mutant) + HA2<br />
	**[[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]] - IvHA1 (mutant) + HA2<br />		**[[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]] - IvHA1 (mutant) + HA2<br />
	**[[2viu]], [[3vun]], [[5thf]] - IvHA1 (mutant) + HA2 (mutant) <br />		**[[2viu]], [[3vun]], [[5thf]] - IvHA1 (mutant) + HA2 (mutant) <br />
Line 127:		Line 136:
	**[[5vtv]] - IvHA1 + HA2 (mutant) + sialic acid derivative<br />		**[[5vtv]] - IvHA1 + HA2 (mutant) + sialic acid derivative<br />
	**[[3htp]], [[3htq]], [[3htt]], [[2rft]], [[2rfu]], [[1rv0]], [[1rvt]], [[1rvx]], [[1rvz]], [[1mqm]], [[1mqn]], [[1hgd]], [[1hge]], [[1hgf]], [[1hgg]], [[1hgh]], [[1hgi]], [[1hgj]], [[3m5h]], [[3m5i]], [[3m5j]], [[4kom]], [[4kon]], [[4lkg]], [[4lkh]], [[4lki]], [[4lkj]], [[4lkk]], [[4n60]], [[4n61]] [[4n62]], [[4n63]], [[4n64]] - IvHA1 + HA2 + polysaccharide<br />		**[[3htp]], [[3htq]], [[3htt]], [[2rft]], [[2rfu]], [[1rv0]], [[1rvt]], [[1rvx]], [[1rvz]], [[1mqm]], [[1mqn]], [[1hgd]], [[1hge]], [[1hgf]], [[1hgg]], [[1hgh]], [[1hgi]], [[1hgj]], [[3m5h]], [[3m5i]], [[3m5j]], [[4kom]], [[4kon]], [[4lkg]], [[4lkh]], [[4lki]], [[4lkj]], [[4lkk]], [[4n60]], [[4n61]] [[4n62]], [[4n63]], [[4n64]] - IvHA1 + HA2 + polysaccharide<br />
-	**[[3eyk]], [[3eym]] - IvHA1 + HA2 + membrane-fusion inhibitor<br />	+	**[[3eyk]], [[3eym]], [[6cfg]], [[6cf7]], [[6cex]] - IvHA1 + HA2 + membrane-fusion inhibitor<br />
	**[[4eef]] - IvHA1 + HA2 + HA-binding protein<br />		**[[4eef]] - IvHA1 + HA2 + HA-binding protein<br />
	**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />		**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />
	**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />		**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />
-	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]], [[6b3m]], [[5wko]], [[5w6g]], [[5ug0]] - IvHA1 + HA2 + antibody<br />	+	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]], [[6b3m]], [[5wko]], [[5w6g]], [[5ug0]], [[6nz7]], [[6ml8]], [[6ii9]], [[6ii8]], [[6ii4]], [[6fyw]], [[6fyu]], [[6fyt]], [[6e3h]], [[5y2m]], [[5y2l]], [[5xku]], [[5w42]] - IvHA1 + HA2 + antibody<br />
	**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />		**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />
-	**[[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]] - IvHA1 + HA2 + antibody – Cryo EM<br />	+	**[[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]], [[6mlm]], [[6hjp]], [[6hjq]] - IvHA1 + HA2 + antibody – Cryo EM<br />
	**[[5w6u]], [[5w6t]], [[5w6r]], [[5w6i]], [[5w5u]], [[5w5s]], [[5vli]] - IvHA1 + HA2 + peptide<br />		**[[5w6u]], [[5w6t]], [[5w6r]], [[5w6i]], [[5w5u]], [[5w5s]], [[5vli]] - IvHA1 + HA2 + peptide<br />
	**[[5kuy]] - IvHA1 + HA2 (mutant) + polypeptide inhibitor<br />		**[[5kuy]] - IvHA1 + HA2 (mutant) + polypeptide inhibitor<br />
Line 144:		Line 153:
	**[[1v2i]], [[1v3b]] – hpvHN 3 – Human parainfluenza virus<br />		**[[1v2i]], [[1v3b]] – hpvHN 3 – Human parainfluenza virus<br />
	**[[4mze]] – hpvPIV 3 (mutant) <br />		**[[4mze]] – hpvPIV 3 (mutant) <br />
-	**[[1v3c]], [[1v3d]], [[1v3e]], [[4wef]], [[4xjq]], [[4xjr]], [[4mza]] – hpvHN 3 + glucoside<br />	+	**[[1v3c]], [[1v3d]], [[1v3e]], [[4wef]], [[4xjq]], [[4xjr]], [[4mza]], [[6c0m]] – hpvHN 3 + glucoside<br />
	**[[4jf7]] - hpv 5 + glucoside<br />		**[[4jf7]] - hpv 5 + glucoside<br />
	**[[5kv8]], [[5kv9]] – hPIV + inhibitor <br />		**[[5kv8]], [[5kv9]] – hPIV + inhibitor <br />
Line 157:		Line 166:
	**[[5b2c]] - MvHN - Mumps virus<br />		**[[5b2c]] - MvHN - Mumps virus<br />
	**[[5b2d]] - MvHN + sialyllactose<br />		**[[5b2d]] - MvHN + sialyllactose<br />
		+	**[[gjjn]], [[6jjm]] – HN – mumps rubulavirus<br />

	*Measles virus hemagglutinin		*Measles virus hemagglutinin

Michal Harel at 09:39, 20 June 2018

Michal Harel — Wed, 20 Jun 2018 09:39:37 GMT

←Older revision		Revision as of 09:39, 20 June 2018
Line 146:		Line 146:
	**[[1v3c]], [[1v3d]], [[1v3e]], [[4wef]], [[4xjq]], [[4xjr]], [[4mza]] – hpvHN 3 + glucoside<br />		**[[1v3c]], [[1v3d]], [[1v3e]], [[4wef]], [[4xjq]], [[4xjr]], [[4mza]] – hpvHN 3 + glucoside<br />
	**[[4jf7]] - hpv 5 + glucoside<br />		**[[4jf7]] - hpv 5 + glucoside<br />
		+	**[[5kv8]], [[5kv9]] – hPIV + inhibitor <br />
	**[[4mze]] - hpvHN 3 (mutant) + glucoside<br />		**[[4mze]] - hpvHN 3 (mutant) + glucoside<br />
	**[[3tsi]] – hpvHN 5 stalk domain<br />		**[[3tsi]] – hpvHN 5 stalk domain<br />

Michal Harel at 09:25, 20 June 2018

Michal Harel — Wed, 20 Jun 2018 09:25:06 GMT

←Older revision		Revision as of 09:25, 20 June 2018
Line 94:		Line 94:
	**[[2jrd]], [[1ibn]], [[1ibo]] – IvHA fusion domain – NMR<br />		**[[2jrd]], [[1ibn]], [[1ibo]] – IvHA fusion domain – NMR<br />
	**[[2dci]], [[1xoo]], [[1xop]] - IvHA fusion domain (mutant) – NMR<br />		**[[2dci]], [[1xoo]], [[1xop]] - IvHA fusion domain (mutant) – NMR<br />
-	**[[2ibx]], [[1ti8]], [[2wr0]], [[2wr1]], [[2wr2]], [[2wr3]], [[2wr4]], [[2wr5]], [[2wr7]], [[2wrb]], [[2wrc]], [[2wrd]], [[2wre]], [[2wrf]], [[2wrg]], [[2wrh]], [[3uyw]], [[4wa1]], [[4we8]], [[4wea]], [[4wsr]] – IvHA<br />	+	**[[2ibx]], [[1ti8]], [[2wr0]], [[2wr1]], [[2wr2]], [[2wr3]], [[2wr4]], [[2wr5]], [[2wr7]], [[2wrb]], [[2wrc]], [[2wrd]], [[2wre]], [[2wrf]], [[2wrg]], [[2wrh]], [[3uyw]], [[4wa1]], [[4we8]], [[4wea]], [[4wsr]], [[6d8w]] – IvHA<br />
	**[[4we9]], [[4wss]] - IvHA + sialic acid derivative<br />		**[[4we9]], [[4wss]] - IvHA + sialic acid derivative<br />
	**[[4f23]] - IvHA precursor<br />		**[[4f23]] - IvHA precursor<br />
Line 102:		Line 102:
	*''IvHA subunit HA1''		*''IvHA subunit HA1''

		+	**[[4we6]], [[4we7]], [[5xl2]] – IvHA1<br />
	**[[3qqi]], [[3mlh]] - IvHA1 receptor-binding domain <br />		**[[3qqi]], [[3mlh]] - IvHA1 receptor-binding domain <br />
-	**[[2yp2]], [[2yp3]], [[2yp4]], [[2yp5]], [[2yp7]], [[2yp8]], [[2yp9]], [[3uyx]], [[4fiu]] - IvHA1 (mutant)<br />	+	**[[2yp2]], [[2yp3]], [[2yp4]], [[2yp5]], [[2yp7]], [[2yp8]], [[2yp9]], [[3uyx]], [[4fiu]], [[5xl8]] - IvHA1 (mutant)<br />
-	**[[~~4we6~~]], [[~~4we7~~]] – IvHA1<br />	+	**[[5xla]], [[5xl9]] - IvHA1 (mutant) + sialic acid derivative<br />
	**[[2vis]], [[2vit]] - IvHA1 (mutant) + antibody<br />		**[[2vis]], [[2vit]] - IvHA1 (mutant) + antibody<br />
-	**[[4fqj]], [[4hkx]], [[4fp8]], [[4m5z]] - IvHA1 + antibody<br />	+	**[[4fqj]], [[4hkx]], [[4fp8]], [[4m5z]], [[5xhv]], [[5w0d]], [[5w08]], [[5vag]] - IvHA1 + antibody<br />

	*''IvHA subunit HA2''		*''IvHA subunit HA2''
Line 116:		Line 117:
	*''IvHA subunit HA1+HA2''		*''IvHA subunit HA1+HA2''

-	**[[3m5g]], [[3al4]], [[3lzg]], [[3m6s]], [[3ku3]], [[3ku5]], [[3hto]], [[3eyj]], [[3bt6]], [[1ru7]], [[1ruy]], [[1ruz]], [[1rd8]], [[1mql]], [[1htm]], [[2hmg]], [[3hmg]], [[4hmg]], [[5hmg]], [[1jsd]], [[1jsm]], [[3s11]], [[3s12]], [[3s13]], [[2ypg]], [[4dj6]], [[4dj7]], [[4dj8]], [[4bgw]], [[4bgz]], [[4bh2]], [[4bsa]], [[4bsg]], [[4eda]], [[4edb]], [[4h32]], [[4k62]], [[4k63]], [[4kdq]], [[4kpq]], [[4kps]], [[4fnk]], [[4fqm]], [[4k3x]], [[4kol]], [[4kth]], [[4lcx]], [[4ln3]], [[4ln6]], [[4lxv]], [[4m40]], [[4mc5]], [[4mhi]], [[4n5j]], [[4n5k]], [[4cyv]], [[4juk]], [[4jul]], [[4jum]], [[4jun]], [[4kw1]], [[4kwm]], [[4o5n]], [[4qy0]], [[4uo0]], [[4uo4]], [[4w8n]], [[4we4]], [[4we5]], [[4wst]], [[4wsw]], [[4wsx]], [[4xkd]], [[4xq5]], [[5vjk]], [[5tg8]], [[5huf]], [[5hu8]], [[5dut]], [[5bny]], [[4unz]], [[4uny]], [[4unx]], [[4unw]], [[4d00]] - IvHA1 + HA2<br />	+	**[[3m5g]], [[3al4]], [[3lzg]], [[3m6s]], [[3ku3]], [[3ku5]], [[3hto]], [[3eyj]], [[3bt6]], [[1ru7]], [[1ruy]], [[1ruz]], [[1rd8]], [[1mql]], [[1htm]], [[2hmg]], [[3hmg]], [[4hmg]], [[5hmg]], [[1jsd]], [[1jsm]], [[3s11]], [[3s12]], [[3s13]], [[2ypg]], [[4dj6]], [[4dj7]], [[4dj8]], [[4bgw]], [[4bgz]], [[4bh2]], [[4bsa]], [[4bsg]], [[4eda]], [[4edb]], [[4h32]], [[4k62]], [[4k63]], [[4kdq]], [[4kpq]], [[4kps]], [[4fnk]], [[4fqm]], [[4k3x]], [[4kol]], [[4kth]], [[4lcx]], [[4ln3]], [[4ln6]], [[4lxv]], [[4m40]], [[4mc5]], [[4mhi]], [[4n5j]], [[4n5k]], [[4cyv]], [[4juk]], [[4jul]], [[4jum]], [[4jun]], [[4kw1]], [[4kwm]], [[4o5n]], [[4qy0]], [[4uo0]], [[4uo4]], [[4w8n]], [[4we4]], [[4we5]], [[4wst]], [[4wsw]], [[4wsx]], [[4xkd]], [[4xq5]], [[5vjk]], [[5tg8]], [[5huf]], [[5hu8]], [[5dut]], [[5bny]], [[4unz]], [[4uny]], [[4unx]], [[4unw]], [[4d00]], [[6d7u]], [[6d8b]], [[6d8d]], [[6d7c]], [[6bkp]], [[6aor]], [[6aoq]], [[5xl1]] - IvHA1 + HA2<br />
-	**[[4cqp]], [[4cqq]], [[4cqr]], [[4cqs]], [[4cqu]], [[4cqv]], [[4cr0]], [[4uo3]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]], 3ku6, 4f3z, [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[5thb]], [[5th0]], [[5tgo]], [[4zcj]] - IvHA1 (mutant) + HA2<br />	+	**[[4cqp]], [[4cqq]], [[4cqr]], [[4cqs]], [[4cqu]], [[4cqv]], [[4cr0]], [[4uo3]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]], [[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[5thb]], [[5th0]], [[5tgo]], [[4zcj]], [[6bko]], [[6bkn]], [[6bkm]], [[6aop]], [[5xlb]], [[5xl5]], [[5vtz]], [[5vtx]], [[5vtu]] - IvHA1 (mutant) + HA2<br />
	**[[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]] - IvHA1 (mutant) + HA2<br />		**[[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]] - IvHA1 (mutant) + HA2<br />
	**[[2viu]], [[3vun]], [[5thf]] - IvHA1 (mutant) + HA2 (mutant) <br />		**[[2viu]], [[3vun]], [[5thf]] - IvHA1 (mutant) + HA2 (mutant) <br />
	**[[4i78]], [[4m4y]], [[3qqb]], [[3qqe]], [[3qqo]] - IvHA1 + HA2 (mutant)<br />		**[[4i78]], [[4m4y]], [[3qqb]], [[3qqe]], [[3qqo]] - IvHA1 + HA2 (mutant)<br />
-	**[[1jsh]], [[1jsi]], [[1jsn]], [[1jso]], [[4bgx]], [[4bgy]], [[4bh0]], [[4bh1]], [[4bh3]], [[4bh4]], [[4bsb]], [[4bsc]], [[4bsd]], [[4bsh]], [[4bsi]], [[4jtv]], [[4k64]], [[3znk]], [[3znl]], [[3znm]], [[3zp0]], [[3zp1]], [[4ln4]], [[4ln8]], [[4m44]], [[4bse]], [[4bsf]], [[4cyw]], [[4cyz]], [[4cz0]], [[4n62]], [[4qy1]], [[4qy2]], [[4uo1]], [[4uo2]], [[4uo5]], [[4uo6]], [[4uo7]], [[4uo8]], [[4uoa]], [[4wa2]], [[4wsu]], [[4wsv]], [[4xke]], [[4xkf]], [[4xkg]], [[4xqo]], [[4xqu]], [[5ajm]], [[5tg9]], [[5br6]], [[5br3]], [[5br0]], [[5bqz]], [[5bqy]], [[4yyb]], [[4yya]], [[4yy9]], [[4yy7]], [[4yy1]], [[4yy0]] - IvHA1 + HA2 + sialic acid derivative<br />	+	**[[1jsh]], [[1jsi]], [[1jsn]], [[1jso]], [[4bgx]], [[4bgy]], [[4bh0]], [[4bh1]], [[4bh3]], [[4bh4]], [[4bsb]], [[4bsc]], [[4bsd]], [[4bsh]], [[4bsi]], [[4jtv]], [[4k64]], [[3znk]], [[3znl]], [[3znm]], [[3zp0]], [[3zp1]], [[4ln4]], [[4ln8]], [[4m44]], [[4bse]], [[4bsf]], [[4cyw]], [[4cyz]], [[4cz0]], [[4n62]], [[4qy1]], [[4qy2]], [[4uo1]], [[4uo2]], [[4uo5]], [[4uo6]], [[4uo7]], [[4uo8]], [[4uoa]], [[4wa2]], [[4wsu]], [[4wsv]], [[4xke]], [[4xkf]], [[4xkg]], [[4xqo]], [[4xqu]], [[5ajm]], [[5tg9]], [[5br6]], [[5br3]], [[5br0]], [[5bqz]], [[5bqy]], [[4yyb]], [[4yya]], [[4yy9]], [[4yy7]], [[4yy1]], [[4yy0]], [[6bkt]], [[6aov]], [[6aou]], [[6aot]], [[6aos]], [[5xl4]], [[5xl3]] - IvHA1 + HA2 + sialic acid derivative<br />
-	**[[3ubj]], [[3ube]], [[3ubn]], [[3ubq]], [[4k66]], [[4k67]], [[4kdn]], [[4kdo]], [[3zp3]], [[3zp2]], [[3zp6]], [[3zpb]], [[4cqw]], [[4cqx]], [[4cqy]], [[4cqz]], [[4uo9]], [[5vjm]], [[5vjl]], [[5thc]], [[5th1]], [[5tgv]], [[5tgu]], [[5e35]], [[5e34]], [[5e32]], [[5e30]], [[5e2z]], [[5e2y]] - IvHA1 (mutant) + HA2 + sialic acid derivative<br />	+	**[[6cf5]], [[6ce6]] - IvHA1 + HA2 + taurine derivative<br />
		+	**[[3ubj]], [[3ube]], [[3ubn]], [[3ubq]], [[4k66]], [[4k67]], [[4kdn]], [[4kdo]], [[3zp3]], [[3zp2]], [[3zp6]], [[3zpb]], [[4cqw]], [[4cqx]], [[4cqy]], [[4cqz]], [[4uo9]], [[5vjm]], [[5vjl]], [[5thc]], [[5th1]], [[5tgv]], [[5tgu]], [[5e35]], [[5e34]], [[5e32]], [[5e30]], [[5e2z]], [[5e2y]], [[6bks]], [[6bkr]], [[6bkq]], [[5xld]], [[5xlc]], [[5xl7]], [[5xl6]], [[5vu4]], [[5vty]], [[5vtw]], [[5vtr]], [[5vtq]], [[5vmj]], [[5vmg]], [[5vmf]], [[5vmc]], [[5t0e]], [[5t0d]], [[5t0b]], [[5t08]] - IvHA1 (mutant) + HA2 + sialic acid derivative<br />
		+	**[[5vtv]] - IvHA1 + HA2 (mutant) + sialic acid derivative<br />
	**[[3htp]], [[3htq]], [[3htt]], [[2rft]], [[2rfu]], [[1rv0]], [[1rvt]], [[1rvx]], [[1rvz]], [[1mqm]], [[1mqn]], [[1hgd]], [[1hge]], [[1hgf]], [[1hgg]], [[1hgh]], [[1hgi]], [[1hgj]], [[3m5h]], [[3m5i]], [[3m5j]], [[4kom]], [[4kon]], [[4lkg]], [[4lkh]], [[4lki]], [[4lkj]], [[4lkk]], [[4n60]], [[4n61]] [[4n62]], [[4n63]], [[4n64]] - IvHA1 + HA2 + polysaccharide<br />		**[[3htp]], [[3htq]], [[3htt]], [[2rft]], [[2rfu]], [[1rv0]], [[1rvt]], [[1rvx]], [[1rvz]], [[1mqm]], [[1mqn]], [[1hgd]], [[1hge]], [[1hgf]], [[1hgg]], [[1hgh]], [[1hgi]], [[1hgj]], [[3m5h]], [[3m5i]], [[3m5j]], [[4kom]], [[4kon]], [[4lkg]], [[4lkh]], [[4lki]], [[4lkj]], [[4lkk]], [[4n60]], [[4n61]] [[4n62]], [[4n63]], [[4n64]] - IvHA1 + HA2 + polysaccharide<br />
	**[[3eyk]], [[3eym]] - IvHA1 + HA2 + membrane-fusion inhibitor<br />		**[[3eyk]], [[3eym]] - IvHA1 + HA2 + membrane-fusion inhibitor<br />
Line 128:		Line 131:
	**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />		**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />
	**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />		**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />
-	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]] - IvHA1 + HA2 + antibody<br />	+	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]], [[6b3m]], [[5wko]], [[5w6g]], [[5ug0]] - IvHA1 + HA2 + antibody<br />
	**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />		**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />
		+	**[[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]] - IvHA1 + HA2 + antibody – Cryo EM<br />
		+	**[[5w6u]], [[5w6t]], [[5w6r]], [[5w6i]], [[5w5u]], [[5w5s]], [[5vli]] - IvHA1 + HA2 + peptide<br />
		+	**[[5kuy]] - IvHA1 + HA2 (mutant) + polypeptide inhibitor<br />

	*Viral hemagglutinin-neuraminidase		*Viral hemagglutinin-neuraminidase

Joel L. Sussman at 18:18, 28 December 2017

Joel L. Sussman — Thu, 28 Dec 2017 18:18:42 GMT

←Older revision		Revision as of 18:18, 28 December 2017
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	**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />		**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />
	**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />		**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />
-	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy~~]], [[3sm5~~]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]] - IvHA1 + HA2 + antibody<br />	+	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]] - IvHA1 + HA2 + antibody<br />
	**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />		**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />

Michal Harel at 08:28, 11 June 2017

Michal Harel — Sun, 11 Jun 2017 08:28:25 GMT

Michal Harel at 23:47, 12 January 2017

Michal Harel — Thu, 12 Jan 2017 23:47:32 GMT

←Older revision		Revision as of 23:47, 12 January 2017
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	1. On the target cell, HA binds the receptor on the cell membrane which is contains sialic acid <ref>Gottschalk A. Chemistry of virus receptors. The Viruses. 1959;3:51–61.</ref> allowing the virus/cell interaction.		1. On the target cell, HA binds the receptor on the cell membrane which is contains sialic acid <ref>Gottschalk A. Chemistry of virus receptors. The Viruses. 1959;3:51–61.</ref> allowing the virus/cell interaction.
	2. HA induce the fusion between the host cell and the virus which can entry into the cytoplasm.		2. HA induce the fusion between the host cell and the virus which can entry into the cytoplasm.
-	Because the HA are the major Antigens of the Virus, [[Antibody\|Antibodies]] recognized them and for this reason HA often change. '''Hemagglutinin-neuraminidase''' (HN) is multifunctional. It possesses both the receptor recognition and neuraminidase activities<ref>PMID:21680512</ref>.	+	Because the HA are the major Antigens of the Virus, [[Antibody\|Antibodies]] recognized them and for this reason HA often change. '''Hemagglutinin-neuraminidase''' (HN) is multifunctional. It possesses both the receptor recognition and neuraminidase activities<ref>PMID:21680512</ref>. For details see [[Mumps Virus Hemagglutinin Neuraminidase Protein]].

	For discussion of influenza hemagglutinin see<br />		For discussion of influenza hemagglutinin see<br />

Michal Harel at 23:45, 12 January 2017

Michal Harel — Thu, 12 Jan 2017 23:45:59 GMT

←Older revision		Revision as of 23:45, 12 January 2017
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	<StructureSection load='' size='350' side='right' scene ='Hemagglutinin/Blackground2wre/1' caption='Structure of glycosylated viral hemagglutinin trimer complex with galactose ([[2wre]])'>		<StructureSection load='' size='350' side='right' scene ='Hemagglutinin/Blackground2wre/1' caption='Structure of glycosylated viral hemagglutinin trimer complex with galactose ([[2wre]])'>
	== Function ==		== Function ==
-	[[Hemagglutinin\|Hemagglutinins]] (HA) are one of the two antigenic Glycoproteins inserted into the influenza virus' membrane. There are at least 16 different forms of HA ~~Antigens~~ classified from H1 to H16. H1, H2, H3 are specific to human [[influenza]]. HAs have two main functions crucial for the [[Viral Infections\|viral infection]] cycle:	+	[[Hemagglutinin\|Hemagglutinins]] (HA) are one of the two antigenic Glycoproteins inserted into the influenza virus' membrane. There are at least 16 different forms of HA antigens classified from H1 to H16. H1, H2, H3 are specific to human [[influenza]]. HAs have two main functions crucial for the [[Viral Infections\|viral infection]] cycle:
	1. On the target cell, HA binds the receptor on the cell membrane which is contains sialic acid <ref>Gottschalk A. Chemistry of virus receptors. The Viruses. 1959;3:51–61.</ref> allowing the virus/cell interaction.		1. On the target cell, HA binds the receptor on the cell membrane which is contains sialic acid <ref>Gottschalk A. Chemistry of virus receptors. The Viruses. 1959;3:51–61.</ref> allowing the virus/cell interaction.
	2. HA induce the fusion between the host cell and the virus which can entry into the cytoplasm.		2. HA induce the fusion between the host cell and the virus which can entry into the cytoplasm.
-	Because the HA are the major Antigens of the Virus, [[Antibody\|Antibodies]] recognized them and for this reason HA often change.	+	Because the HA are the major Antigens of the Virus, [[Antibody\|Antibodies]] recognized them and for this reason HA often change. '''Hemagglutinin-neuraminidase''' (HN) is multifunctional. It possesses both the receptor recognition and neuraminidase activities<ref>PMID:21680512</ref>.

	For discussion of influenza hemagglutinin see<br />		For discussion of influenza hemagglutinin see<br />

Michal Harel at 23:36, 12 January 2017

Michal Harel — Thu, 12 Jan 2017 23:36:05 GMT

←Older revision		Revision as of 23:36, 12 January 2017
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	*Viral hemagglutinin-neuraminidase		*Viral hemagglutinin-neuraminidase

-	**[[1usx]] – ~~NvPIV~~ head domain + thiosialoside – Newcastle ~~diasease~~ virus<br />	+	**[[1usx]], [[4fzh]], [[3t1e]] – NvHN head domain + thiosialoside – Newcastle disease virus<br />
-	**[[1usr]], [[1e8t]], [[1e8u]], [[1e8v]], [[4fzh]] - ~~NvPIV~~ head domain<br />	+	**[[1usr]], [[1e8t]], [[1e8u]], [[1e8v]], [[4fzh]] - NvHN head domain<br />
-	**[[3t1e]] - ~~NvPIV~~ ectodomain<br />	+	**[[3t1e]] - NvHN ectodomain<br />
-	**[[1v2i~~]], [[2v3b~~]], [[1v3b~~]], [[4mza]], [[4xjq~~]] – ~~hPIV~~ – Human parainfluenza virus<br />	+	**[[1v2i]], [[1v3b]] – hpvHN 3 – Human parainfluenza virus<br />
-	**[[4mze]] – ~~hPIV~~ (mutant) <br />	+	**[[4mze]] – hpvPIV 3 (mutant) <br />
-	**[[~~2v3c~~]], [[~~2v3d~~]], [[~~1v3c~~]], [[~~1v3d~~]], [[~~1v3e~~]], [[~~4wef~~]] – ~~hPIV~~ + glucoside<br />	+	**[[1v3c]], [[1v3d]], [[1v3e]], [[4wef]], [[4xjq]], [[4xjr]], [[4mza]] – hpvHN 3 + glucoside<br />
-	**[[~~2v3e~~]] ~~– hPIV~~ + ~~zanamavir~~<br />	+	**[[4jf7]] - hpv 5 + glucoside<br />
-	**[[3tsi]] – ~~hPIV~~ stalk domain<br />	+	**[[4mze]] - hpvHN 3 (mutant) + glucoside<br />
-	**[[1z4v]], [[1z4w]], [[1z4z]], [[1z50]] – ~~SvPIV~~ extracellular domain + DANA – Simian virus<br />	+	**[[3tsi]] – hpvHN 5 stalk domain<br />
-	**[[1z4x]], [[1z4y]] - ~~SvPIV~~ extracellular domain + glucoside<br />	+	**[[1z4v]], [[1z4w]], [[1z4z]], [[1z50]] – SvHN extracellular domain + DANA – Simian virus<br />
-	**[[4jf7]] - ~~SvPIV~~ extracellular domain<br />	+	**[[1z4x]], [[1z4y]] - SvHN extracellular domain + glucoside<br />
		+	**[[4jf7]] - SvHN extracellular domain<br />
	**[[2vsk]], [[2vsm]] – HN ephrin-binding domain + ephrin – Hendra virus<br />		**[[2vsk]], [[2vsm]] – HN ephrin-binding domain + ephrin – Hendra virus<br />
	**[[2vwd]], [[3d11]] - NivHN receptor-binding domain – Nipah virus<br />		**[[2vwd]], [[3d11]] - NivHN receptor-binding domain – Nipah virus<br />

←Older revision		Revision as of 08:28, 11 June 2017
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	**[[4ouj]] – CbHA33 (mutant)<br />		**[[4ouj]] – CbHA33 (mutant)<br />
	**[[4qd2]] – CbHA33 + HA17 + HA70 + cadherin<br />		**[[4qd2]] – CbHA33 + HA17 + HA70 + cadherin<br />
		+	**[[3win]] – CbHA1 + HA2 + HA3 <br />
	**[[3a5p]] – HA I – slime mold<br />		**[[3a5p]] – HA I – slime mold<br />
	**[[4fbr]] – MxHA – ''Myxococcus xanthus''<br />		**[[4fbr]] – MxHA – ''Myxococcus xanthus''<br />
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	**[[4f23]] - IvHA precursor<br />		**[[4f23]] - IvHA precursor<br />
	**[[1ha0]] – IvHA precursor (mutant) <br />		**[[1ha0]] – IvHA precursor (mutant) <br />
		+	**[[3whe]], [[4lvh]] - IvHA + antibody<br />

	*''IvHA subunit HA1''		*''IvHA subunit HA1''
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	*''IvHA subunit HA2''		*''IvHA subunit HA2''

-	**[[1qu1]] – IvHA2<br />	+	**[[1qu1]], [[4nkj]] – IvHA2<br />
	**[[4p67]], [[4s1x]] – IvHA2 (mutant) <br />		**[[4p67]], [[4s1x]] – IvHA2 (mutant) <br />
		+	**[[4oxm]] – IvHA2 coiled coil<br />

	*''IvHA subunit HA1+HA2''		*''IvHA subunit HA1+HA2''

-	**[[3m5g]], [[3al4]], [[3lzg]], [[3m6s]], [[3ku3]], [[3ku5]], [[3hto]], [[3eyj]], [[3bt6]], [[1ru7]], [[1ruy]], [[1ruz]], [[1rd8]], [[1mql]], [[1htm]], [[2hmg]], [[3hmg]], [[4hmg]], [[5hmg]], [[1jsd]], [[1jsm]], [[3s11]], [[3s12]], [[3s13]], [[2ypg]], [[4dj6]], [[4dj7]], [[4dj8]], [[4bgw]], [[4bgz]], [[4bh2]], [[4bsa]], [[4bsg]], [[4eda]], [[4edb]], [[4h32]], [[4k62]], [[4k63]], [[4kdq]], [[4kpq]], [[4kps]], [[4fnk]], [[4fqm]], [[4k3x]], [[4kol]], [[4kth]], [[4lcx]], [[4ln3]], [[4ln6]], [[4lxv]], [[4m40]], [[4mc5]], [[4mhi]], [[4n5j]], [[4n5k]], [[4cyv]], [[4juk]], [[4jul]], [[4jum]], [[4jun]], [[4kw1]], [[4kwm]], [[4o5n]], [[4qy0]], [[4uo0]], [[4uo4]], [[4w8n]], [[4we4]], [[4we5]], [[4wst]], [[4wsw]], [[4wsx]], [[4xkd]], [[4xq5]] - IvHA1 + HA2<br />	+	**[[3m5g]], [[3al4]], [[3lzg]], [[3m6s]], [[3ku3]], [[3ku5]], [[3hto]], [[3eyj]], [[3bt6]], [[1ru7]], [[1ruy]], [[1ruz]], [[1rd8]], [[1mql]], [[1htm]], [[2hmg]], [[3hmg]], [[4hmg]], [[5hmg]], [[1jsd]], [[1jsm]], [[3s11]], [[3s12]], [[3s13]], [[2ypg]], [[4dj6]], [[4dj7]], [[4dj8]], [[4bgw]], [[4bgz]], [[4bh2]], [[4bsa]], [[4bsg]], [[4eda]], [[4edb]], [[4h32]], [[4k62]], [[4k63]], [[4kdq]], [[4kpq]], [[4kps]], [[4fnk]], [[4fqm]], [[4k3x]], [[4kol]], [[4kth]], [[4lcx]], [[4ln3]], [[4ln6]], [[4lxv]], [[4m40]], [[4mc5]], [[4mhi]], [[4n5j]], [[4n5k]], [[4cyv]], [[4juk]], [[4jul]], [[4jum]], [[4jun]], [[4kw1]], [[4kwm]], [[4o5n]], [[4qy0]], [[4uo0]], [[4uo4]], [[4w8n]], [[4we4]], [[4we5]], [[4wst]], [[4wsw]], [[4wsx]], [[4xkd]], [[4xq5]], [[5vjk]], [[5tg8]], [[5huf]], [[5hu8]], [[5dut]], [[5bny]], [[4unz]], [[4uny]], [[4unx]], [[4unw]], [[4d00]] - IvHA1 + HA2<br />
-	**[[4cqp]], [[4cqq]], [[4cqr]], [[4cqs]], [[4cqu]], [[4cqv]], [[4cr0]], [[4uo3]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]], 3ku6, 4f3z, [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]] - IvHA1 (mutant) + HA2<br />	+	**[[4cqp]], [[4cqq]], [[4cqr]], [[4cqs]], [[4cqu]], [[4cqv]], [[4cr0]], [[4uo3]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]], 3ku6, 4f3z, [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[5thb]], [[5th0]], [[5tgo]], [[4zcj]] - IvHA1 (mutant) + HA2<br />
	**[[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]] - IvHA1 (mutant) + HA2<br />		**[[3ku6]], [[4f3z]], [[4jtx]], [[4ju0]], [[4jug]], [[4juh]], [[4juj]], [[4k65]], [[4kdm]], [[3zpa]], [[4gxx]], [[4n5y]], [[4n5z]], [[4nrj]], [[4nrk]], [[4nrl]] - IvHA1 (mutant) + HA2<br />
-	**[[2viu]], [[3vun]] - IvHA1 (mutant) + HA2 (mutant) <br />	+	**[[2viu]], [[3vun]], [[5thf]] - IvHA1 (mutant) + HA2 (mutant) <br />
	**[[4i78]], [[4m4y]], [[3qqb]], [[3qqe]], [[3qqo]] - IvHA1 + HA2 (mutant)<br />		**[[4i78]], [[4m4y]], [[3qqb]], [[3qqe]], [[3qqo]] - IvHA1 + HA2 (mutant)<br />
-	**[[1jsh]], [[1jsi]], [[1jsn]], [[1jso]], [[4bgx]], [[4bgy]], [[4bh0]], [[4bh1]], [[4bh3]], [[4bh4]], [[4bsb]], [[4bsc]], [[4bsd]], [[4bsh]], [[4bsi]], [[4jtv]], [[4k64]], [[3znk]], [[3znl]], [[3znm]], [[3zp0]], [[3zp1]], [[4ln4]], [[4ln8]], [[4m44]], [[4bse]], [[4bsf]], [[4cyw]], [[4cyz]], [[4cz0]], [[4n62]], [[4qy1]], [[4qy2]], [[4uo1]], [[4uo2]], [[4uo5]], [[4uo6]], [[4uo7]], [[4uo8]], [[4uoa]], [[4wa2]], [[4wsu]], [[4wsv]], [[4xke]], [[4xkf]], [[4xkg]], [[4xqo]], [[4xqu]], [[5ajm]] - IvHA1 + HA2 + sialic acid derivative<br />	+	**[[1jsh]], [[1jsi]], [[1jsn]], [[1jso]], [[4bgx]], [[4bgy]], [[4bh0]], [[4bh1]], [[4bh3]], [[4bh4]], [[4bsb]], [[4bsc]], [[4bsd]], [[4bsh]], [[4bsi]], [[4jtv]], [[4k64]], [[3znk]], [[3znl]], [[3znm]], [[3zp0]], [[3zp1]], [[4ln4]], [[4ln8]], [[4m44]], [[4bse]], [[4bsf]], [[4cyw]], [[4cyz]], [[4cz0]], [[4n62]], [[4qy1]], [[4qy2]], [[4uo1]], [[4uo2]], [[4uo5]], [[4uo6]], [[4uo7]], [[4uo8]], [[4uoa]], [[4wa2]], [[4wsu]], [[4wsv]], [[4xke]], [[4xkf]], [[4xkg]], [[4xqo]], [[4xqu]], [[5ajm]], [[5tg9]], [[5br6]], [[5br3]], [[5br0]], [[5bqz]], [[5bqy]], [[4yyb]], [[4yya]], [[4yy9]], [[4yy7]], [[4yy1]], [[4yy0]] - IvHA1 + HA2 + sialic acid derivative<br />
-	**[[3ubj]], [[3ube]], [[3ubn]], [[3ubq]], [[4k66]], [[4k67]], [[4kdn]], [[4kdo]], [[3zp3]], [[3zp2]], [[3zp6]], [[3zpb]], [[4cqw]], [[4cqx]], [[4cqy]], [[4cqz]], [[4uo9]] - IvHA1 (mutant) + HA2 + sialic acid derivative<br />	+	**[[3ubj]], [[3ube]], [[3ubn]], [[3ubq]], [[4k66]], [[4k67]], [[4kdn]], [[4kdo]], [[3zp3]], [[3zp2]], [[3zp6]], [[3zpb]], [[4cqw]], [[4cqx]], [[4cqy]], [[4cqz]], [[4uo9]], [[5vjm]], [[5vjl]], [[5thc]], [[5th1]], [[5tgv]], [[5tgu]], [[5e35]], [[5e34]], [[5e32]], [[5e30]], [[5e2z]], [[5e2y]] - IvHA1 (mutant) + HA2 + sialic acid derivative<br />
	**[[3htp]], [[3htq]], [[3htt]], [[2rft]], [[2rfu]], [[1rv0]], [[1rvt]], [[1rvx]], [[1rvz]], [[1mqm]], [[1mqn]], [[1hgd]], [[1hge]], [[1hgf]], [[1hgg]], [[1hgh]], [[1hgi]], [[1hgj]], [[3m5h]], [[3m5i]], [[3m5j]], [[4kom]], [[4kon]], [[4lkg]], [[4lkh]], [[4lki]], [[4lkj]], [[4lkk]], [[4n60]], [[4n61]] [[4n62]], [[4n63]], [[4n64]] - IvHA1 + HA2 + polysaccharide<br />		**[[3htp]], [[3htq]], [[3htt]], [[2rft]], [[2rfu]], [[1rv0]], [[1rvt]], [[1rvx]], [[1rvz]], [[1mqm]], [[1mqn]], [[1hgd]], [[1hge]], [[1hgf]], [[1hgg]], [[1hgh]], [[1hgi]], [[1hgj]], [[3m5h]], [[3m5i]], [[3m5j]], [[4kom]], [[4kon]], [[4lkg]], [[4lkh]], [[4lki]], [[4lkj]], [[4lkk]], [[4n60]], [[4n61]] [[4n62]], [[4n63]], [[4n64]] - IvHA1 + HA2 + polysaccharide<br />
	**[[3eyk]], [[3eym]] - IvHA1 + HA2 + membrane-fusion inhibitor<br />		**[[3eyk]], [[3eym]] - IvHA1 + HA2 + membrane-fusion inhibitor<br />
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	**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />		**[[3r2x]] – IvHA1 receptor-binding domain + HA2 fusion subunit + designed HA-binding protein <br />
	**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />		**[[2fk0]] - IvHA14 receptor-binding domain + HA2 membrane-fusion domain<br />
-	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3sm5]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]] - IvHA1 + HA2 + antibody<br />	+	**[[3lzf]], [[3gbm]], [[3gbn]], [[3fku]], [[1ken]], [[1eo8]], [[1qfu]], [[2vir]], [[3sdy]], [[3sm5]], [[3ztj]], [[3ztn]], [[4gms]], [[4f15]], [[4hf5]], [[4hfu]], [[4hg4]], [[4hlz]], [[4kvn]], [[4fqi]], [[4fqk]], [[4gxu]], [[4fqr]], [[4fqv]], [[4fqy]], [[4mhh]], [[4mhj]], [[4nm8]], [[4o58]], [[4o5i]], [[4py8]], [[5v2a]], [[5umn]], [[5ugy]], [[5kaq]], [[5kan]], [[5k9q]], [[5k9o]], [[5k9k]], [[5jw4]], [[5jw3]], [[5ibl]], [[5gjt]], [[5gjs]], [[5dur]], [[5dup]], [[5dum]], [[5a3i]], [[4yk4]], [[4yjz]], [[4xrc]], [[4xnq]], [[4xnm]], [[4ubd]], [[4r8w]] - IvHA1 + HA2 + antibody<br />
		+	**[[5t6s]], [[5t6n]] - IvHA1 + HA2 + drug<br />

	*Viral hemagglutinin-neuraminidase		*Viral hemagglutinin-neuraminidase