Lignin peroxidase - Revision history

Michal Harel at 10:33, 17 October 2021

Michal Harel — Sun, 17 Oct 2021 10:33:12 GMT

←Older revision		Revision as of 10:33, 17 October 2021
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	[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />		[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />
	[[1b85]], [[6a6q]], [[6iss]] – PcLip (mutant)<br />		[[1b85]], [[6a6q]], [[6iss]] – PcLip (mutant)<br />
-	[[3q3u]] – Lip – ''Trametes cervina''	+	[[3q3u]] – Lip – ''Trametes cervina''<br />
		+	[[7oo5]] – Lip – ''Agrocybe pediades''<br />

	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 10:01, 31 August 2020

Michal Harel — Mon, 31 Aug 2020 10:01:50 GMT

←Older revision		Revision as of 10:01, 31 August 2020
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	[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />		[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />
-	[[1b85]], [[6a6q]] – PcLip (mutant)<br />	+	[[1b85]], [[6a6q]], [[6iss]] – PcLip (mutant)<br />
	[[3q3u]] – Lip – ''Trametes cervina''		[[3q3u]] – Lip – ''Trametes cervina''

Michal Harel at 09:58, 31 August 2020

Michal Harel — Mon, 31 Aug 2020 09:58:53 GMT

←Older revision		Revision as of 09:58, 31 August 2020
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	<StructureSection load='' size='450' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='48/486472/Cv/1'>		<StructureSection load='' size='450' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='48/486472/Cv/1'>
	== Function ==		== Function ==
-	'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.	+	'''Lignin peroxidase''' or '''ligninase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.

	== Relevance ==		== Relevance ==

Michal Harel at 08:33, 22 October 2019

Michal Harel — Tue, 22 Oct 2019 08:33:30 GMT

←Older revision		Revision as of 08:33, 22 October 2019
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	==3D structures of lignin peroxidase==		==3D structures of lignin peroxidase==

		+	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

	[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />		[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />

Michal Harel at 08:31, 22 October 2019

Michal Harel — Tue, 22 Oct 2019 08:31:38 GMT

←Older revision		Revision as of 08:31, 22 October 2019
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	[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />		[[1lga]], [[1llp]], [[1qpa]], [[1b80]], [[1b82]] – PcLip – ''Phanerochaete chrysosporium''<br />
-	[[1b85]] – PcLip (mutant)<br />	+	[[1b85]], [[6a6q]] – PcLip (mutant)<br />
	[[3q3u]] – Lip – ''Trametes cervina''		[[3q3u]] – Lip – ''Trametes cervina''

Alexander Berchansky at 10:36, 8 July 2019

Alexander Berchansky — Mon, 08 Jul 2019 10:36:26 GMT

←Older revision		Revision as of 10:36, 8 July 2019
Line 7:		Line 7:

	== Structural highlights ==		== Structural highlights ==
-	*<scene name='48/486472/Cv/3'>Heme binding site</scene>.	+	*<scene name='48/486472/Cv/8'>Heme binding site</scene>. Water molecules are shown as red spheres.
-	*<scene name='48/486472/Cv/4'>Fe coordination site</scene>.	+	*<scene name='48/486472/Cv/9'>Fe coordination site</scene>.
-	*<scene name='48/486472/Cv/5'>Cl coordination site</scene>.	+	*<scene name='48/486472/Cv/10'>Cl coordination site</scene>.
-	*<scene name='48/486472/Cv/6'>1st Ca coordination site</scene>.	+	*<scene name='48/486472/Cv/13'>1st Ca coordination site</scene>.
-	*<scene name='48/486472/Cv/7'>2nd Ca coordination site</scene>.	+	*<scene name='48/486472/Cv/14'>2nd Ca coordination site</scene>.
	</StructureSection>		</StructureSection>
	==3D structures of lignin peroxidase==		==3D structures of lignin peroxidase==

Joel L. Sussman at 14:35, 9 August 2017

Joel L. Sussman — Wed, 09 Aug 2017 14:35:08 GMT

←Older revision		Revision as of 14:35, 9 August 2017
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-	<StructureSection load='~~3q3u~~' size='450' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='48/486472/Cv/1'>	+	<StructureSection load='' size='450' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='48/486472/Cv/1'>
	== Function ==		== Function ==
	'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.		'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.

Alexander Berchansky at 14:08, 9 August 2017

Alexander Berchansky — Wed, 09 Aug 2017 14:08:32 GMT

←Older revision		Revision as of 14:08, 9 August 2017
Line 1:		Line 1:
-	<StructureSection load='3q3u' size='~~350~~' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='48/486472/Cv/1'>	+	<StructureSection load='3q3u' size='450' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='48/486472/Cv/1'>
	== Function ==		== Function ==
	'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.		'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.
Line 5:		Line 5:
	== Relevance ==		== Relevance ==
	Lip is used as a skin-lightening active agent<ref>PMID:25574195</ref>.		Lip is used as a skin-lightening active agent<ref>PMID:25574195</ref>.
		+
		+	== Structural highlights ==
		+	*<scene name='48/486472/Cv/3'>Heme binding site</scene>.
		+	*<scene name='48/486472/Cv/4'>Fe coordination site</scene>.
		+	*<scene name='48/486472/Cv/5'>Cl coordination site</scene>.
		+	*<scene name='48/486472/Cv/6'>1st Ca coordination site</scene>.
		+	*<scene name='48/486472/Cv/7'>2nd Ca coordination site</scene>.
	</StructureSection>		</StructureSection>
	==3D structures of lignin peroxidase==		==3D structures of lignin peroxidase==

Alexander Berchansky at 13:29, 9 August 2017

Alexander Berchansky — Wed, 09 Aug 2017 13:29:52 GMT

←Older revision		Revision as of 13:29, 9 August 2017
Line 1:		Line 1:
-		+	<StructureSection load='3q3u' size='350' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='48/486472/Cv/1'>
-	<StructureSection load='3q3u' size='350' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='>	+
	== Function ==		== Function ==
	'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.		'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.

Michal Harel at 09:22, 4 July 2017

Michal Harel — Tue, 04 Jul 2017 09:22:59 GMT

←Older revision		Revision as of 09:22, 4 July 2017
Line 1:		Line 1:
-	{{STRUCTURE_3q3u\| PDB=3q3u \| SIZE=400\| SCENE= \|right\|CAPTION=Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions [[3q3u]] }}

		+	<StructureSection load='3q3u' size='350' side='right' caption='Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry [[3q3u]])' scene='>
	== Function ==		== Function ==
	'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.		'''Lignin peroxidase''' (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction<ref>PMID:9790672</ref>.
Line 6:		Line 6:
	== Relevance ==		== Relevance ==
	Lip is used as a skin-lightening active agent<ref>PMID:25574195</ref>.		Lip is used as a skin-lightening active agent<ref>PMID:25574195</ref>.
-		+	</StructureSection>
	==3D structures of lignin peroxidase==		==3D structures of lignin peroxidase==