Methylamine utilisation protein - Revision history

Michal Harel at 09:46, 9 August 2022

Michal Harel — Tue, 09 Aug 2022 09:46:55 GMT

←Older revision		Revision as of 09:46, 9 August 2022
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-	<StructureSection load='3pxt' size='340' side='right' caption='MauG containing hydroxytryptophan (grey, green) complex with MADH light chain(magenta, pink), MADH heavy chain (yellow, cyan), acetate, PEG, tetra ethylene glycol Na+, Ca+2 (PDB ID [[3pxt]])' scene=''>	+	<StructureSection load='3pxt' size='340' side='right' caption='MauG containing hydroxytryptophan (grey, green) complex with MADH light chain (magenta, pink), MADH heavy chain (yellow, cyan), acetate, PEG, tetra ethylene glycol Na+, Ca+2 (PDB ID [[3pxt]])' scene=''>

	== Function ==		== Function ==

-	'''Methylamine utilisation protein'''. (MauG) is a 2 c type heme protein (in which the heme is covalently bound to the protein) which catalyses the post translational modification of tryptophan cryptophilquinone biosynthesis within methylamine dehydrogenase (MADH). The catalysis process is a remote one involving hole hopping mechanism of electron transfer in which ~~Top~~ residues are reversibly oxidized<ref>PMID:24144526</ref>. MauG catalyses the 6-electron oxidation of MADH using hydrogen peroxide or oxygen.	+	'''Methylamine utilisation protein'''. (MauG) is a 2 c type heme protein (in which the heme is covalently bound to the protein) which catalyses the post translational modification of tryptophan cryptophilquinone biosynthesis within methylamine dehydrogenase (MADH). The catalysis process is a remote one involving hole hopping mechanism of electron transfer in which Trp residues are reversibly oxidized<ref>PMID:24144526</ref>. MauG catalyses the 6-electron oxidation of MADH using hydrogen peroxide or oxygen.

-	== ~~Disease~~ ==	+	== Structural highlights ==

-	== ~~Relevance~~ ==	+	The type c heme moiety is coordinated to 5 MauG residues<ref>PMID:21355604</ref>.
		+	==3D structures of MauG==

-	~~== Structural highlights ==~~	+	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

-	~~This is a sample scene created with SAT to~~ <~~scene name="~~/~~12/3456/Sample/1"~~>~~color~~</~~scene~~> ~~by Group~~, ~~and another to make~~ <~~scene name="~~/12/~~3456/Sample~~/2">~~a transparent representation~~</~~scene~~> ~~of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.~~	+	[[3l4m]], [[3pxs]], [[4fa1]], [[4fa4]], [[4fa5]], [[4fa9]], [[4fan]], [[4fav]], [[4fb1]] – PdMauG + MADH – ''Paracoccus dentrificans''<br />
		+	[[3orv]], [[3sle]], [[3rlm]], [[3rmz]], [[3rn0]], [[3rn1]], [[3sjl]], [[3svw]], [[4l1q]], [[4l3g]], [[4l3h]], [[4o1q]], [[4y5r]] – PdMauG (mutant) + MADH<br />
		+	[[3sxt]], [[4k3i]] – PdMauG + MADH (quinol)<br />
		+	[[3sws]] – PdMauG + MADH (quinone)<br />
		+	[[3pxw]] – PdMauG + MADH + NO<br />
		+	[[3pxt]] – PdMauG + MADH + CO<br />

	</StructureSection>		</StructureSection>

Michal Harel at 09:41, 9 August 2022

Michal Harel — Tue, 09 Aug 2022 09:41:19 GMT

←Older revision		Revision as of 09:41, 9 August 2022
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-	<StructureSection load='3pxt' size='340' side='right' caption='~~Caption for this structure~~' scene=''>	+	<StructureSection load='3pxt' size='340' side='right' caption='MauG containing hydroxytryptophan (grey, green) complex with MADH light chain(magenta, pink), MADH heavy chain (yellow, cyan), acetate, PEG, tetra ethylene glycol Na+, Ca+2 (PDB ID [[3pxt]])' scene=''>

	== Function ==		== Function ==

Michal Harel at 09:34, 9 August 2022

Michal Harel — Tue, 09 Aug 2022 09:34:36 GMT

←Older revision		Revision as of 09:34, 9 August 2022
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-		+	<StructureSection load='3pxt' size='340' side='right' caption='Caption for this structure' scene=''>
-	<StructureSection load='~~1stp~~' size='340' side='right' caption='Caption for this structure' scene=''>	+

	== Function ==		== Function ==

-	'''Methylamine utilisation protein'''. (MauG) is a 2 c type heme protein (in which the heme is covalently bound to the protein) which catalyses the post translational modification of tryptophan cryptophilquinone biosynthesis within methylamine dehydrogenase. The catalysis process is a remote one involving hole hopping mechanism of electron transfer in which Top residues are reversibly oxidized<ref>PMID:24144526</ref>.	+	'''Methylamine utilisation protein'''. (MauG) is a 2 c type heme protein (in which the heme is covalently bound to the protein) which catalyses the post translational modification of tryptophan cryptophilquinone biosynthesis within methylamine dehydrogenase (MADH). The catalysis process is a remote one involving hole hopping mechanism of electron transfer in which Top residues are reversibly oxidized<ref>PMID:24144526</ref>. MauG catalyses the 6-electron oxidation of MADH using hydrogen peroxide or oxygen.

	== Disease ==		== Disease ==
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	== References ==		== References ==
	<references/>		<references/>
		+	[[Category:Topic Page]]

Michal Harel: New page: == Function == '''Methylamine utilisation protein'''. (MauG) is a 2 c type heme prot...

Michal Harel — Tue, 09 Aug 2022 09:18:56 GMT

New page: <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Methylamine utilisation protein'''. (MauG) is a 2 c type heme prot...

New page

<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>

== Function ==

'''Methylamine utilisation protein'''. (MauG) is a 2 c type heme protein (in which the heme is covalently bound to the protein) which catalyses the post translational modification of tryptophan cryptophilquinone biosynthesis within methylamine dehydrogenase. The catalysis process is a remote one involving hole hopping mechanism of electron transfer in which Top residues are reversibly oxidized<ref>PMID:24144526</ref>.

== Disease ==

== Relevance ==

== Structural highlights ==

This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

</StructureSection>
== References ==
<references/>