Molecular Playground/Alginate - Revision history

Joe White at 14:43, 29 March 2011

Joe White — Tue, 29 Mar 2011 14:43:37 GMT

←Older revision		Revision as of 14:43, 29 March 2011
Line 3:		Line 3:
	One of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].		One of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].

-	Alginate is a ~~natural,~~ linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a ~~thickener in food processing and~~ biomaterial for ~~tissue~~ engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.	+	Alginate is a linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a biomaterial for cellular engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.

-	[~~[Image:PFOB-Alginate Swatch Wet small.jpg\|~~frame~~\|left\|~~Alginate ~~hydrogel on gauze swatch]]~~	+	<applet size='[450,338]' frame='true' align='right'
		+	caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>

-	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, ~~barium~~, etc.) ~~causes the guluronic acid residues to~~ chemically cross-~~link, and the ensuing entanglements cause the~~ alginate ~~solution to form~~ a ~~hydrogel~~. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source ~~and native climate~~. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms ~~and locations~~. The rotating molecule to the right is an example of a short chain of sodium alginate.	+	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, magnesium, etc.) chemically cross-links alginate solutions forming a gel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.

	Molecular Playground banner: A short, linear chain of sodium alginate.		Molecular Playground banner: A short, linear chain of sodium alginate.
-	<applet size='[450,338]' frame='true' align='right'
-	caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>

Joe White: Molecular Playground/Alginate-newFall2010 moved to Molecular Playground/Alginate over redirect: Need to revert back in order to create the new updated page

Joe White — Tue, 29 Mar 2011 14:42:45 GMT

Molecular Playground/Alginate-newFall2010 moved to Molecular Playground/Alginate over redirect: Need to revert back in order to create the new updated page

←Older revision

Revision as of 14:42, 29 March 2011

Joe White: Molecular Playground/Alginate moved to Molecular Playground/Alginate-newFall2010: Page updated by new author

Joe White — Tue, 29 Mar 2011 14:37:42 GMT

Molecular Playground/Alginate moved to Molecular Playground/Alginate-newFall2010: Page updated by new author

←Older revision

Revision as of 14:37, 29 March 2011

Joe White at 14:30, 29 March 2011

Joe White — Tue, 29 Mar 2011 14:30:56 GMT

←Older revision		Revision as of 14:30, 29 March 2011
Line 3:		Line 3:
	One of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].		One of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].

-	Alginate is a linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a thickener in food processing and biomaterial for tissue engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.	+	Alginate is a natural, linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a thickener in food processing and biomaterial for tissue engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.

	[[Image:PFOB-Alginate Swatch Wet small.jpg\|frame\|left\|Alginate hydrogel on gauze swatch]]		[[Image:PFOB-Alginate Swatch Wet small.jpg\|frame\|left\|Alginate hydrogel on gauze swatch]]

-	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, barium, etc.) causes the guluronic acid residues to chemically cross-link, and the ensuing entanglements cause the alginate solution to form a hydrogel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source and native climate. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.	+	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, barium, etc.) causes the guluronic acid residues to chemically cross-link, and the ensuing entanglements cause the alginate solution to form a hydrogel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source and native climate. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms and locations. The rotating molecule to the right is an example of a short chain of sodium alginate.

	Molecular Playground banner: A short, linear chain of sodium alginate.		Molecular Playground banner: A short, linear chain of sodium alginate.
	<applet size='[450,338]' frame='true' align='right'		<applet size='[450,338]' frame='true' align='right'
	caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>		caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>

Joe White at 17:18, 9 December 2010

Joe White — Thu, 09 Dec 2010 17:18:31 GMT

←Older revision		Revision as of 17:18, 9 December 2010
Line 5:		Line 5:
	Alginate is a linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a thickener in food processing and biomaterial for tissue engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.		Alginate is a linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a thickener in food processing and biomaterial for tissue engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.

-	~~<applet size='~~[~~450,338]'~~ frame~~='true' align='right'~~	+	[[Image:PFOB-Alginate Swatch Wet small.jpg\|frame\|left\|Alginate hydrogel on gauze swatch]]
-	~~caption='Sodium~~ Alginate ~~(24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>~~	+

	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, barium, etc.) causes the guluronic acid residues to chemically cross-link, and the ensuing entanglements cause the alginate solution to form a hydrogel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source and native climate. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.		Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, barium, etc.) causes the guluronic acid residues to chemically cross-link, and the ensuing entanglements cause the alginate solution to form a hydrogel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source and native climate. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.

	Molecular Playground banner: A short, linear chain of sodium alginate.		Molecular Playground banner: A short, linear chain of sodium alginate.
-		+	<applet size='[450,338]' frame='true' align='right'
-	[~~[Image:PFOB-Alginate Swatch Wet small.jpg\|~~frame~~\|left\|~~Alginate ~~hydrogel on gauze swatch]]~~	+	caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>

Joe White at 23:43, 8 December 2010

Joe White — Wed, 08 Dec 2010 23:43:04 GMT

←Older revision		Revision as of 23:43, 8 December 2010
Line 11:		Line 11:

	Molecular Playground banner: A short, linear chain of sodium alginate.		Molecular Playground banner: A short, linear chain of sodium alginate.
		+
		+	[[Image:PFOB-Alginate Swatch Wet small.jpg\|frame\|left\|Alginate hydrogel on gauze swatch]]

Joe White at 23:13, 8 December 2010

Joe White — Wed, 08 Dec 2010 23:13:54 GMT

←Older revision		Revision as of 23:13, 8 December 2010
Line 8:		Line 8:
	caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>		caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>

-	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, barium, etc.) chemically cross-~~links~~ alginate ~~solutions forming~~ a ~~gel~~. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.	+	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, barium, etc.) causes the guluronic acid residues to chemically cross-link, and the ensuing entanglements cause the alginate solution to form a hydrogel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source and native climate. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.

	Molecular Playground banner: A short, linear chain of sodium alginate.		Molecular Playground banner: A short, linear chain of sodium alginate.

Joe White at 22:56, 8 December 2010

Joe White — Wed, 08 Dec 2010 22:56:32 GMT

←Older revision		Revision as of 22:56, 8 December 2010
Line 3:		Line 3:
	One of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].		One of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].

-	Alginate is a linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a biomaterial for ~~cellular~~ engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.	+	Alginate is a linear, organic polymer isolated from bacteria and algae. It has been shown to be biocompatible (non-toxic to human cells) and has thus found numerous applications as a thickener in food processing and biomaterial for tissue engineering. Owing to its unique physical properties, alginate hydrogels have been used as a scaffold material for building artificial organs, as a dressing for ulcerous wounds and as a vector for the targeted delivery of anti-cancer drugs.

	<applet size='[450,338]' frame='true' align='right'		<applet size='[450,338]' frame='true' align='right'
	caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>		caption='Sodium Alginate (24,000 Da)' scene='User:David_Griffin/Sandbox_1/Alginate_24000da/1'/>

-	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, ~~magnesium~~, etc.) chemically cross-links alginate solutions forming a gel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.	+	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, barium, etc.) chemically cross-links alginate solutions forming a gel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.

	Molecular Playground banner: A short, linear chain of sodium alginate.		Molecular Playground banner: A short, linear chain of sodium alginate.

David Griffin at 17:18, 12 May 2010

David Griffin — Wed, 12 May 2010 17:18:21 GMT

←Older revision		Revision as of 17:18, 12 May 2010
Line 10:		Line 10:
	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, magnesium, etc.) chemically cross-links alginate solutions forming a gel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.		Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, magnesium, etc.) chemically cross-links alginate solutions forming a gel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.

-	Molecular Playground banner: A short chain of sodium alginate.	+	Molecular Playground banner: A short, linear chain of sodium alginate.

David Griffin at 23:19, 2 May 2010

David Griffin — Sun, 02 May 2010 23:19:24 GMT

←Older revision		Revision as of 23:19, 2 May 2010
Line 9:		Line 9:

	Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, magnesium, etc.) chemically cross-links alginate solutions forming a gel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.		Alginate is composed of a random sequence of mannuronic acid (M) and guluronic acid (G). Exposure to divalent cations (e.g. calcium, magnesium, etc.) chemically cross-links alginate solutions forming a gel. Alginate can vary widely in length, monomeric sequence and G/M ratio depending on the source. The ratio of G/M in the chain influences the strength of alginate hydrogels and can be tuned by combining alginate obtained from different organisms. The rotating molecule to the right is an example of a short chain of sodium alginate.
		+
		+	Molecular Playground banner: A short chain of sodium alginate.