Pleurotolysin - Revision history

Alexander Berchansky at 12:45, 8 August 2019

Alexander Berchansky — Thu, 08 Aug 2019 12:45:26 GMT

←Older revision		Revision as of 12:45, 8 August 2019
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	== Function ==		== Function ==
-	'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>. <scene name='75/751804/Cv/3'>Pleurotoxin A complex with pleurotoxin B</scene> ([[4v3a]]).	+	'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>. <scene name='75/751804/Cv/4'>Pleurotoxin A complex with pleurotoxin B</scene> ([[4v3a]]).

	</StructureSection>		</StructureSection>

Alexander Berchansky at 12:41, 8 August 2019

Alexander Berchansky — Thu, 08 Aug 2019 12:41:28 GMT

←Older revision		Revision as of 12:41, 8 August 2019
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	== Function ==		== Function ==
-	'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>. <scene name='75/751804/Cv/2'>Pleurotoxin A complex with pleurotoxin B</scene> ([[4v3a]]).	+	'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>. <scene name='75/751804/Cv/3'>Pleurotoxin A complex with pleurotoxin B</scene> ([[4v3a]]).

	</StructureSection>		</StructureSection>

Michal Harel at 22:55, 21 October 2017

Michal Harel — Sat, 21 Oct 2017 22:55:58 GMT

←Older revision		Revision as of 22:55, 21 October 2017
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-	<StructureSection load='' size='340' side='right' caption='Pleurotoxin A (~~sky~~ blue and green) complex with pleurotoxin B (~~deeppink~~) (PDB code [[4v3a]])' scene='75/751804/Cv/1' pspeed='8'>	+	<StructureSection load='' size='340' side='right' caption='Pleurotoxin A (blue and green) complex with pleurotoxin B (pink) (PDB code [[4v3a]])' scene='75/751804/Cv/1' pspeed='8'>

	== Function ==		== Function ==
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	== References ==		== References ==
	<references/>		<references/>
		+	[[Category:Topic Page]]

Joel L. Sussman at 13:36, 4 September 2017

Joel L. Sussman — Mon, 04 Sep 2017 13:36:00 GMT

←Older revision		Revision as of 13:36, 4 September 2017
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-	<StructureSection load='~~4v3a~~' size='340' side='right' caption='Pleurotoxin A (sky blue and green) complex with pleurotoxin B (deeppink) (PDB code [[4v3a]])' scene='75/751804/Cv/1' pspeed='8'>	+	<StructureSection load='' size='340' side='right' caption='Pleurotoxin A (sky blue and green) complex with pleurotoxin B (deeppink) (PDB code [[4v3a]])' scene='75/751804/Cv/1' pspeed='8'>

	== Function ==		== Function ==

Alexander Berchansky at 09:58, 4 September 2017

Alexander Berchansky — Mon, 04 Sep 2017 09:58:00 GMT

←Older revision		Revision as of 09:58, 4 September 2017
Line 2:		Line 2:

	== Function ==		== Function ==
-	'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>.	+	'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>. <scene name='75/751804/Cv/2'>Pleurotoxin A complex with pleurotoxin B</scene> ([[4v3a]]).

	</StructureSection>		</StructureSection>

Alexander Berchansky at 09:52, 4 September 2017

Alexander Berchansky — Mon, 04 Sep 2017 09:52:29 GMT

←Older revision		Revision as of 09:52, 4 September 2017
Line 1:		Line 1:
-	<StructureSection load='4v3a' size='340' side='right' caption='Pleurotoxin A (~~grey~~ and green) complex with pleurotoxin B (~~pink~~) (PDB code [[4v3a]])' scene=''>	+	<StructureSection load='4v3a' size='340' side='right' caption='Pleurotoxin A (sky blue and green) complex with pleurotoxin B (deeppink) (PDB code [[4v3a]])' scene='75/751804/Cv/1' pspeed='8'>

	== Function ==		== Function ==

Michal Harel at 10:16, 1 February 2017

Michal Harel — Wed, 01 Feb 2017 10:16:30 GMT

←Older revision		Revision as of 10:16, 1 February 2017
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-		+	<StructureSection load='4v3a' size='340' side='right' caption='Pleurotoxin A (grey and green) complex with pleurotoxin B (pink) (PDB code [[4v3a]])' scene=''>
-	<StructureSection load='4v3a' size='340' side='right' caption='~~Caption for this structure~~' scene=''>	+

	== Function ==		== Function ==
	'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>.		'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>.
-
-	== Structural highlights ==

	</StructureSection>		</StructureSection>

Michal Harel: New page: == Function == '''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus...

Michal Harel — Wed, 01 Feb 2017 10:13:31 GMT

New page: <StructureSection load='4v3a' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus...

New page

<StructureSection load='4v3a' size='340' side='right' caption='Caption for this structure' scene=''>

== Function ==
'''Pleurotolysin''' (PTL) is a pore-forming cytolysin from ''Pleurotus ostreatus''. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis<ref>PMID:15084605</ref>.

== Structural highlights ==

</StructureSection>
==3D structures of pleurotolysin==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

* Pleurotolysin A

**[[4oeb]] – PoPTL – ''Pleurotus ostreatus''<br />

* Pleurotolysin B

**[[4oej]] – PoPTL <br />
**[[4ov8]] – PoPTL (mutant)<br />

* Pleurotolysin A+B

**[[4v2t]], [[4v3a]], [[4v3m]], [[4v3n]] – PoPTL - CryoEM<br />
}}
== References ==
<references/>