Resolvase - Revision history

Michal Harel at 10:46, 8 December 2019

Michal Harel — Sun, 08 Dec 2019 10:46:19 GMT

←Older revision		Revision as of 10:46, 8 December 2019
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	</StructureSection>		</StructureSection>
-	==3D structures of resolvase==

-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	* Holliday junction resolvase
-
-	**[[2wiw]], [[2wiz]], [[2wj0]] – AfHJR+DNA – ''Archaeoglobus fulgidus''<br />
-	**[[2wcw]], [[2wcz]] – AfHJR (mutant)<br />
-	**[[2h8c]] – EcHJR RusA (mutant) + DNA – ''Escherichia coli''<br />
-	**[[1gdt]] - EcHJR +DNA<br />
-	**[[2h8e]] - EcHJR RusA (mutant)<br />
-	**[[1q8r]] – EcHJR RusA<br />
-	**[[1hjr]] – EcHJR RuvC<br />
-	**[[4ep4]] – TtHJR RuvC – ''Thermus thermophilus''<br />
-	**[[4ep5]] – TtHJR RuvC (mutant)<br />
-	**[[1zp7]] – BsHJR RecU – ''Bacillus subtilis''<br />
-	**[[5fdk]] - BsHJR RecU (mutant) + DNA<br />
-	**[[1ob8]], [[1ob9]], [[1hh1]], [[2eo0]] – SsHJR – ''Sulfolobus solfataricus''<br />
-	**[[4tkd]], [[4tkk]] - SsHJR (mutant) - <br />
-	**[[2fco]] – HJR – ''Geobacillus kaustophilus''<br />
-	**[[1ipi]], [[1gef]] – PfHJR – ''Pyrococcus furiosus''<br />
-	**[[1kcf]] – HJR – fission yeast<br />
-	**[[1bvs]] - RuvA - ''Mycobacterium leprae''<br />
-	**[[5e6f]] - HJR - canarypox virus<br />
-
-	* Ser-recombinase
-
-	**[[2rsl]] - EcGDR<br />
-	**[[1hx7]] – EcGDR N-terminal – NMR<br />
-	**[[1ght]], [[1res]], [[1ret]], [[1ght]] – EcGDR catalytic domain – NMR<br />
-	**[[1gdr]], [[1hx7]] - EcGDR catalytic domain<br />
-	**[[2gm4]], [[1zr2]], [[1zr4]], [[1gdt]] – EcGDR+DNA<br />
-	**[[2gm5]] – EcGDR (mutant)<br />
-	**[[3guv]] – Sp-site-specific recombinase – ''Streptococcus pneumoniae''<br />
-	**[[2r0q]] – SaS-rec+DNA – ''Staphylococcus aureus''<br />
-	**[[3pkz]] - SaS-sin (mutant)<br />
-	**[[3lhf]] – SsS-rec<br />
-
-	* Tyr-recombinase
-
-	**[[3etl]], [[3ew9]], [[3ewa]], [[2i1q]] – MmRadA Rec+AMPPNP+ion – ''Methanococcus maripaludis''<br />
-	**[[2b21]] - MmRadA Rec+AMPPNP<br />
-	**[[2zub]], [[2zuc]], [[2zud]], [[2dfl]] – SsRadA<br />
-	**[[2cvf]], [[2cvh]] – RadB Rec – ''Thermococcus kodakarensis''<br />
-	**[[2f1h]], [[2fpl]], [[2fpm]] - MvRec+AMPPNP+K – ''Methanococcus voltae''<br />
-	**[[2f1i]] – MvRec+AMPPNP<br />
-	**[[2f1j]], [[2fpk]] - MvRec+ADP<br />
-	**[[1a0p]] – EcXerD Rec<br />
-	**[[5dcf]] - EcXerD C-terminal/FTSK<br />
-	**[[5hxy]] - XerD - ''Thermoplasma acidophilum''<br />
-	**[[5jjv]], [[5jk0]] - XerH - ''Helicobacter pylori''<br />
-
-	* Cre recombinase
-
-	**[[3mgv]], [[3c28]], [[3c29]], [[2hof]], [[2hoi]], [[1xns]], [[1xo0]], [[1pvp]], [[1pvq]], [[1pvr]], [[1nzb]], [[1ouq]], [[1q3u]], [[1q3v]], [[1ma7]], [[1kbu]], [[1drg]], [[1f44]], [[2crx]], [[3crx]], [[4crx]], [[5crx]], [[1crx]] – EpCre+DNA – Enterobacteria phage PI<br />
-
-	*Hin recombinase
-
-	**[[1hcr]], [[1ijw]], [[1ijj6]], [[1jj8]], [[1jko]], [[1jkp]], [[1jkq]], [[1jkr]] – HRec + DNA – synthetic <br />
-
-	*RadA recombinase
-
-	**[[2zub]], [[2zuc]], [[2zud]], [[2dfl]] – SsRadA <br />
-	**[[4dc9]] – MvRadA C-terminal domain <br />
-	**[[2i1q]] – MvRadA (mutant) <br />
-	**[[1pzn]], [[5fos]], [[5fot]], [[5fou]], [[5fox]], [[5fpk]], [[5fov]], [[5fow]] – PfRadA <br />
-	**[[4a6p]] – PfRadA ATPase domain (mutant) <br />
-	**[[5lkq]] - SpRadA protease domain<br />
-	**[[5j4l]], [[5jec]], [[5jed]], [[5jee]], [[5kdd]], [[5l8v]], [[5lb2]], [[5lb4]], [[5lbi]], [[5jfg]] - PfRadA (mutant)<br />
-	**[[5h45]] - TtRadA C-terminal<br />
-
-	*RadA recombinase complex
-
-	**[[5fot]], [[5fou]], [[5fov]], [[5fow]], [[5fpk]], [[4b3b]] – PfRadA ATPase domain + tetrapeptide <br />
-	**[[4d6p]] – PfRadA ATPase domain (mutant) + AMPPNP <br />
-	**[[4uqo]] – PfRadA ATPase domain (mutant) + ADP <br />
-	**[[4b2i]] – PfRadA ATPase domain (mutant) + indazole <br />
-	**[[4b2l]], [[4b35]] – PfRadA ATPase domain (mutant) + methylester tryplophan <br />
-	**[[4b32]], [[4b33]] – PfRadA ATPase domain (mutant) + naphthol <br />
-	**[[4b34]] – PfRadA ATPase domain (mutant) + aminobenzothiazole <br />
-	**[[4b3c]], [[4b3d]], [[5j4h]], [[5j4k]] – PfRadA ATPase domain (mutant) + indole derivative <br />
-	**[[4a6x]] – PfRadA ATPase domain (mutant) + ATP <br />
-	**[[3ntu]], [[2gdj]] – MvRadA + AMPPNP <br />
-	**[[2b21]], [[2f1h]], [[2f1i]], [[2fpl]], [[2fpm]] – MvRadA (mutant) + AMPPNP <br />
-	**[[3fyh]], [[2f1j]], [[2fpk]] – MvRadA (mutant) + ADP <br />
-	**[[3etl]], [[3ew9]], [[3ewa]] – MmRadA (mutant) + AMPPNP <br />
-	**[[5lkm]] - SpRadA + TDP<br />
-
-	*RadB recombinase
-
-	**[[2cvf]], [[2cvh]] – TkRadB <br />
-
-	*Integrase see [[Integrase]] and [[Retroviral Integrase]]
-
-	*Recombinase A (RecA) see [[Recombinase A]]
-	}}
	==References==		==References==
	<references />		<references />

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 10:45, 8 December 2019

Michal Harel — Sun, 08 Dec 2019 10:45:00 GMT

←Older revision		Revision as of 10:45, 8 December 2019
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	*'''RadA recombinase''' promotes DNA recombination. Detailed analysis of its <scene name='Resolvase/Cv/2'>dimeric structure</scene> suggests mechanisms for junction isomerization and communication between the two active sites <ref>PMID:19143611</ref>. <br />		*'''RadA recombinase''' promotes DNA recombination. Detailed analysis of its <scene name='Resolvase/Cv/2'>dimeric structure</scene> suggests mechanisms for junction isomerization and communication between the two active sites <ref>PMID:19143611</ref>. <br />
	*'''Hin-recombinase''' (HRec) is a protein of ''Salmonella''. HRec inverts a 900 base pair DNA segment which contains the promoters of flagellar genes. The inversion changes the these genes' expressions<ref>PMID:15454079</ref>.		*'''Hin-recombinase''' (HRec) is a protein of ''Salmonella''. HRec inverts a 900 base pair DNA segment which contains the promoters of flagellar genes. The inversion changes the these genes' expressions<ref>PMID:15454079</ref>.
		+
		+	==3D structures of resolvase==
		+	[[Resolvase 3D structures]]
		+
	</StructureSection>		</StructureSection>
	==3D structures of resolvase==		==3D structures of resolvase==

Michal Harel at 10:55, 4 September 2018

Michal Harel — Tue, 04 Sep 2018 10:55:45 GMT

←Older revision		Revision as of 10:55, 4 September 2018
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	**[[2cvf]], [[2cvh]] – TkRadB <br />		**[[2cvf]], [[2cvh]] – TkRadB <br />

-	*Integrase see [[Integrase]]	+	*Integrase see [[Integrase]] and [[Retroviral Integrase]]

	*Recombinase A (RecA) see [[Recombinase A]]		*Recombinase A (RecA) see [[Recombinase A]]

Michal Harel at 09:40, 4 September 2018

Michal Harel — Tue, 04 Sep 2018 09:40:51 GMT

←Older revision		Revision as of 09:40, 4 September 2018
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	**[[2cvf]], [[2cvh]] – TkRadB <br />		**[[2cvf]], [[2cvh]] – TkRadB <br />

-	* Integrase	+	*Integrase see [[Integrase]]
-		+
-	**[[~~2a3v]] – Rec INTI4+DNA – ''Vibrio cholerae''<br />~~	+
-	**[[3bvp]] – Integrase ~~N-terminal – Lactococcus phage<br />~~	+
-	**[[2oxo]] – LamInt binding domain – phage<br />	+
-	**[[1z19]] – EpLamInt core binding +catalytic domain+DNA<br />	+
-	**[[1z1b]], [[1z1g]], [[1p7d]] – EpLamInt+DNA<br />	+
-	**[[1kjk]] – EpLamInt N-terminal – NMR<br />	+
-	**[[1ae9]] – EpLamInt catalytic core<br />	+
-	**[[1p4e]], [[1m6x]] – yFLP (mutant)+DNA – yeast<br />	+
-	**[[1flo]] - yFLP +DNA<br />	+
-	**[[1aih]] – HP1 integrase catalytic domain - bacteriophage<br />	+
-	**[[3nrw]] – INT/site-specific recombinase N-terminal – ''Haloarcula marismortui''<br />	+
-	**[[3jtz]] – INT arm-type binding domain – ''Yersinia pestis''<br />	+
-	**[[3ju0]] – HPI INT arm-type binding domain – ''Pectobacterium atrosepticum''<br />	+
-	**[[2kkp]] – INT SAM-like domain – ''Moorella thermoacetica'' – NMR<br />	+
-	**[[2kkv]] – INT fragment – ''Salmonella enterica'' – NMR<br />	+
-	**[[2khq]] - INT fragment – ''Staphylococcus saprophyticus'' – NMR<br />	+
-	**[[2wcc]] – λINT DBD+ DNA – Enterobacteria phage λ - NMR<br />	+
-	**[[2khv]], [[2kj5]] – INT residues 102-199 – ''Nitrosospira multiformis'' – NMR<br />	+
-	**[[5udo]] - INT coiled-coil domain - ''Listeria innocua''<br />	+
-	**[[5frn]] ~~- INT + DNA - human spumaretrovirus<br />~~	+

	*Recombinase A (RecA) see [[Recombinase A]]		*Recombinase A (RecA) see [[Recombinase A]]

Joel L. Sussman at 14:23, 26 September 2017

Joel L. Sussman — Tue, 26 Sep 2017 14:23:15 GMT

←Older revision		Revision as of 14:23, 26 September 2017
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-	<StructureSection load='' size='340' side='right' caption='Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]]' scene='' >	+	<StructureSection load='1kcf' size='340' side='right' caption='Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]]' scene='' >
	== Function ==		== Function ==
	[[Resolvase]] or '''recombinase''' (Rec) is a nuclease which is involved in DNA recombination. According to the binding residue, the recombinases are grouped to Tyr- and Ser-recombinase.		[[Resolvase]] or '''recombinase''' (Rec) is a nuclease which is involved in DNA recombination. According to the binding residue, the recombinases are grouped to Tyr- and Ser-recombinase.

Joel L. Sussman at 14:22, 26 September 2017

Joel L. Sussman — Tue, 26 Sep 2017 14:22:58 GMT

←Older revision		Revision as of 14:22, 26 September 2017
Line 1:		Line 1:
-	<StructureSection load='~~1kcf~~' size='340' side='right' caption='Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]]' scene='' >	+	<StructureSection load='' size='340' side='right' caption='Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]]' scene='' >
	== Function ==		== Function ==
	[[Resolvase]] or '''recombinase''' (Rec) is a nuclease which is involved in DNA recombination. According to the binding residue, the recombinases are grouped to Tyr- and Ser-recombinase.		[[Resolvase]] or '''recombinase''' (Rec) is a nuclease which is involved in DNA recombination. According to the binding residue, the recombinases are grouped to Tyr- and Ser-recombinase.

Michal Harel at 18:20, 25 September 2017

Michal Harel — Mon, 25 Sep 2017 18:20:52 GMT

←Older revision		Revision as of 18:20, 25 September 2017
Line 1:		Line 1:
-
	<StructureSection load='1kcf' size='340' side='right' caption='Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]]' scene='' >		<StructureSection load='1kcf' size='340' side='right' caption='Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]]' scene='' >
	== Function ==		== Function ==
Line 26:		Line 25:
	**[[4ep4]] – TtHJR RuvC – ''Thermus thermophilus''<br />		**[[4ep4]] – TtHJR RuvC – ''Thermus thermophilus''<br />
	**[[4ep5]] – TtHJR RuvC (mutant)<br />		**[[4ep5]] – TtHJR RuvC (mutant)<br />
-	**[[1zp7]] – ~~HJR~~ RecU – ''Bacillus subtilis''<br />	+	**[[1zp7]] – BsHJR RecU – ''Bacillus subtilis''<br />
-	**[[1ob8]], [[1ob9]], [[1hh1]] – SsHJR – ''Sulfolobus solfataricus''<br />	+	**[[5fdk]] - BsHJR RecU (mutant) + DNA<br />
		+	**[[1ob8]], [[1ob9]], [[1hh1]], [[2eo0]] – SsHJR – ''Sulfolobus solfataricus''<br />
		+	**[[4tkd]], [[4tkk]] - SsHJR (mutant) - <br />
	**[[2fco]] – HJR – ''Geobacillus kaustophilus''<br />		**[[2fco]] – HJR – ''Geobacillus kaustophilus''<br />
-	**[[1ipi]], [[1gef]] – ~~HJR~~ – ''Pyrococcus furiosus''<br />	+	**[[1ipi]], [[1gef]] – PfHJR – ''Pyrococcus furiosus''<br />
	**[[1kcf]] – HJR – fission yeast<br />		**[[1kcf]] – HJR – fission yeast<br />
		+	**[[1bvs]] - RuvA - ''Mycobacterium leprae''<br />
		+	**[[5e6f]] - HJR - canarypox virus<br />

	* Ser-recombinase		* Ser-recombinase
Line 40:		Line 43:
	**[[2gm4]], [[1zr2]], [[1zr4]], [[1gdt]] – EcGDR+DNA<br />		**[[2gm4]], [[1zr2]], [[1zr4]], [[1gdt]] – EcGDR+DNA<br />
	**[[2gm5]] – EcGDR (mutant)<br />		**[[2gm5]] – EcGDR (mutant)<br />
-	**[[3guv]] – site-specific recombinase – ''Streptococcus pneumoniae''<br />	+	**[[3guv]] – Sp-site-specific recombinase – ''Streptococcus pneumoniae''<br />
-	**[[2r0q]] – S-rec+DNA – ''Staphylococcus aureus''<br />	+	**[[2r0q]] – SaS-rec+DNA – ''Staphylococcus aureus''<br />
		+	**[[3pkz]] - SaS-sin (mutant)<br />
	**[[3lhf]] – SsS-rec<br />		**[[3lhf]] – SsS-rec<br />

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	**[[2f1i]] – MvRec+AMPPNP<br />		**[[2f1i]] – MvRec+AMPPNP<br />
	**[[2f1j]], [[2fpk]] - MvRec+ADP<br />		**[[2f1j]], [[2fpk]] - MvRec+ADP<br />
-	**[[1a0p]] – ~~EcXerd~~ Rec<br />	+	**[[1a0p]] – EcXerD Rec<br />
		+	**[[5dcf]] - EcXerD C-terminal/FTSK<br />
		+	**[[5hxy]] - XerD - ''Thermoplasma acidophilum''<br />
		+	**[[5jjv]], [[5jk0]] - XerH - ''Helicobacter pylori''<br />

	* Cre recombinase		* Cre recombinase
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	**[[4dc9]] – MvRadA C-terminal domain <br />		**[[4dc9]] – MvRadA C-terminal domain <br />
	**[[2i1q]] – MvRadA (mutant) <br />		**[[2i1q]] – MvRadA (mutant) <br />
-	**[[1pzn]] – PfRadA <br />	+	**[[1pzn]], [[5fos]], [[5fot]], [[5fou]], [[5fox]], [[5fpk]], [[5fov]], [[5fow]] – PfRadA <br />
	**[[4a6p]] – PfRadA ATPase domain (mutant) <br />		**[[4a6p]] – PfRadA ATPase domain (mutant) <br />
		+	**[[5lkq]] - SpRadA protease domain<br />
		+	**[[5j4l]], [[5jec]], [[5jed]], [[5jee]], [[5kdd]], [[5l8v]], [[5lb2]], [[5lb4]], [[5lbi]], [[5jfg]] - PfRadA (mutant)<br />
		+	**[[5h45]] - TtRadA C-terminal<br />

	*RadA recombinase complex		*RadA recombinase complex
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	**[[4b32]], [[4b33]] – PfRadA ATPase domain (mutant) + naphthol <br />		**[[4b32]], [[4b33]] – PfRadA ATPase domain (mutant) + naphthol <br />
	**[[4b34]] – PfRadA ATPase domain (mutant) + aminobenzothiazole <br />		**[[4b34]] – PfRadA ATPase domain (mutant) + aminobenzothiazole <br />
-	**[[4b3c]], [[4b3d]] – PfRadA ATPase domain (mutant) + indole <br />	+	**[[4b3c]], [[4b3d]], [[5j4h]], [[5j4k]] – PfRadA ATPase domain (mutant) + indole derivative <br />
	**[[4a6x]] – PfRadA ATPase domain (mutant) + ATP <br />		**[[4a6x]] – PfRadA ATPase domain (mutant) + ATP <br />
	**[[3ntu]], [[2gdj]] – MvRadA + AMPPNP <br />		**[[3ntu]], [[2gdj]] – MvRadA + AMPPNP <br />
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	**[[3fyh]], [[2f1j]], [[2fpk]] – MvRadA (mutant) + ADP <br />		**[[3fyh]], [[2f1j]], [[2fpk]] – MvRadA (mutant) + ADP <br />
	**[[3etl]], [[3ew9]], [[3ewa]] – MmRadA (mutant) + AMPPNP <br />		**[[3etl]], [[3ew9]], [[3ewa]] – MmRadA (mutant) + AMPPNP <br />
		+	**[[5lkm]] - SpRadA + TDP<br />

	*RadB recombinase		*RadB recombinase
Line 111:		Line 122:
	**[[2wcc]] – λINT DBD+ DNA – Enterobacteria phage λ - NMR<br />		**[[2wcc]] – λINT DBD+ DNA – Enterobacteria phage λ - NMR<br />
	**[[2khv]], [[2kj5]] – INT residues 102-199 – ''Nitrosospira multiformis'' – NMR<br />		**[[2khv]], [[2kj5]] – INT residues 102-199 – ''Nitrosospira multiformis'' – NMR<br />
		+	**[[5udo]] - INT coiled-coil domain - ''Listeria innocua''<br />
		+	**[[5frn]] - INT + DNA - human spumaretrovirus<br />

	*Recombinase A (RecA) see [[Recombinase A]]		*Recombinase A (RecA) see [[Recombinase A]]

Michal Harel at 10:15, 28 November 2016

Michal Harel — Mon, 28 Nov 2016 10:15:31 GMT

←Older revision		Revision as of 10:15, 28 November 2016
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-	~~{{STRUCTURE_1kcf\| PDB~~=1kcf ~~\| SIZE~~=~~300\| SCENE~~=~~Resolvase/Cv/1 \|~~right~~\|CAPTION~~=Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]] }}	+
		+	<StructureSection load='1kcf' size='340' side='right' caption='Yeast Holliday junction resolvase dimer complex with sulfate, [[1kcf]]' scene='' >
	== Function ==		== Function ==
	[[Resolvase]] or '''recombinase''' (Rec) is a nuclease which is involved in DNA recombination. According to the binding residue, the recombinases are grouped to Tyr- and Ser-recombinase.		[[Resolvase]] or '''recombinase''' (Rec) is a nuclease which is involved in DNA recombination. According to the binding residue, the recombinases are grouped to Tyr- and Ser-recombinase.
Line 8:		Line 9:
	*'''RadA recombinase''' promotes DNA recombination. Detailed analysis of its <scene name='Resolvase/Cv/2'>dimeric structure</scene> suggests mechanisms for junction isomerization and communication between the two active sites <ref>PMID:19143611</ref>. <br />		*'''RadA recombinase''' promotes DNA recombination. Detailed analysis of its <scene name='Resolvase/Cv/2'>dimeric structure</scene> suggests mechanisms for junction isomerization and communication between the two active sites <ref>PMID:19143611</ref>. <br />
	*'''Hin-recombinase''' (HRec) is a protein of ''Salmonella''. HRec inverts a 900 base pair DNA segment which contains the promoters of flagellar genes. The inversion changes the these genes' expressions<ref>PMID:15454079</ref>.		*'''Hin-recombinase''' (HRec) is a protein of ''Salmonella''. HRec inverts a 900 base pair DNA segment which contains the promoters of flagellar genes. The inversion changes the these genes' expressions<ref>PMID:15454079</ref>.
-		+	</StructureSection>
	==3D structures of resolvase==		==3D structures of resolvase==

Michal Harel at 08:55, 4 August 2016

Michal Harel — Thu, 04 Aug 2016 08:55:02 GMT

←Older revision		Revision as of 08:55, 4 August 2016
Line 61:		Line 61:

	**[[1hcr]], [[1ijw]], [[1ijj6]], [[1jj8]], [[1jko]], [[1jkp]], [[1jkq]], [[1jkr]] – HRec + DNA – synthetic <br />		**[[1hcr]], [[1ijw]], [[1ijj6]], [[1jj8]], [[1jko]], [[1jkp]], [[1jkq]], [[1jkr]] – HRec + DNA – synthetic <br />
		+
		+	*RadA recombinase
		+
		+	**[[2zub]], [[2zuc]], [[2zud]], [[2dfl]] – SsRadA <br />
		+	**[[4dc9]] – MvRadA C-terminal domain <br />
		+	**[[2i1q]] – MvRadA (mutant) <br />
		+	**[[1pzn]] – PfRadA <br />
		+	**[[4a6p]] – PfRadA ATPase domain (mutant) <br />
		+
		+	*RadA recombinase complex
		+
		+	**[[5fot]], [[5fou]], [[5fov]], [[5fow]], [[5fpk]], [[4b3b]] – PfRadA ATPase domain + tetrapeptide <br />
		+	**[[4d6p]] – PfRadA ATPase domain (mutant) + AMPPNP <br />
		+	**[[4uqo]] – PfRadA ATPase domain (mutant) + ADP <br />
		+	**[[4b2i]] – PfRadA ATPase domain (mutant) + indazole <br />
		+	**[[4b2l]], [[4b35]] – PfRadA ATPase domain (mutant) + methylester tryplophan <br />
		+	**[[4b32]], [[4b33]] – PfRadA ATPase domain (mutant) + naphthol <br />
		+	**[[4b34]] – PfRadA ATPase domain (mutant) + aminobenzothiazole <br />
		+	**[[4b3c]], [[4b3d]] – PfRadA ATPase domain (mutant) + indole <br />
		+	**[[4a6x]] – PfRadA ATPase domain (mutant) + ATP <br />
		+	**[[3ntu]], [[2gdj]] – MvRadA + AMPPNP <br />
		+	**[[2b21]], [[2f1h]], [[2f1i]], [[2fpl]], [[2fpm]] – MvRadA (mutant) + AMPPNP <br />
		+	**[[3fyh]], [[2f1j]], [[2fpk]] – MvRadA (mutant) + ADP <br />
		+	**[[3etl]], [[3ew9]], [[3ewa]] – MmRadA (mutant) + AMPPNP <br />
		+
		+	*RadB recombinase
		+
		+	**[[2cvf]], [[2cvh]] – TkRadB <br />

	* Integrase		* Integrase

Michal Harel at 08:02, 4 August 2016

Michal Harel — Thu, 04 Aug 2016 08:02:51 GMT

←Older revision		Revision as of 08:02, 4 August 2016
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	*'''Tyr-recombinases''' include Cre which recombines loxP sites, FLP and lambda integrase (LamInt). <br />		*'''Tyr-recombinases''' include Cre which recombines loxP sites, FLP and lambda integrase (LamInt). <br />
	*'''Ser-recombinases''' (S-rec) include gamma-delta resolvase (GDR), Tn3 resolvase and phiC31 integrase.<br />		*'''Ser-recombinases''' (S-rec) include gamma-delta resolvase (GDR), Tn3 resolvase and phiC31 integrase.<br />
-	*'''RadA recombinase''' promotes DNA recombination. Detailed analysis of its <scene name='Resolvase/Cv/2'>dimeric structure</scene> suggests mechanisms for junction isomerization and communication between the two active sites <ref>PMID:~~11726496~~</ref>. <br />	+	*'''RadA recombinase''' promotes DNA recombination. Detailed analysis of its <scene name='Resolvase/Cv/2'>dimeric structure</scene> suggests mechanisms for junction isomerization and communication between the two active sites <ref>PMID:19143611</ref>. <br />
	*'''Hin-recombinase''' (HRec) is a protein of ''Salmonella''. HRec inverts a 900 base pair DNA segment which contains the promoters of flagellar genes. The inversion changes the these genes' expressions<ref>PMID:15454079</ref>.		*'''Hin-recombinase''' (HRec) is a protein of ''Salmonella''. HRec inverts a 900 base pair DNA segment which contains the promoters of flagellar genes. The inversion changes the these genes' expressions<ref>PMID:15454079</ref>.