Rho guanine nucleotide exchange factor 3D structures - Revision history

Michal Harel at 10:08, 16 October 2023

Michal Harel — Mon, 16 Oct 2023 10:08:59 GMT

←Older revision		Revision as of 10:08, 16 October 2023
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	**[[8bnt]] – hGEF-H1 DH domain 206-448 + RhoA <br />		**[[8bnt]] – hGEF-H1 DH domain 206-448 + RhoA <br />
-	**[[7g80]], [[7g81]], [[7g82]], [[7g83]], [[7g84]], [[7g85]], [[7g86]], [[7g88]], [[7g89]], [[7g8a]], [[7g8b]], [[7g8c]], [[7g8d]], [[7g8e]], [[7g8f]], [[7g8g]], [[7g8h]], [[7g8i]], [[7g8j]], [[7g8k]], [[7g8l]], [[7g8m]], [[7g8n]], [[7g8o]], [[7g8p]], [[7g8q]], [[7g8r]], [[7g87]], [[7g8s]], [[7g8t]], [[7g8u]], [[7g8v]], [[7g8w]], [[7g8x]], [[7g8y]], [[7g8z]], [[7g90]], [[7g91]], [[7g92]], [[7g93]], [[7g94]], [[7g95]], [[7g96]], [[7g97]], [[7g98]], [[7g99]], [[7g9a]], [[7g9b]], [[7g9c]], [[7g9d]], [[7g9e]], [[7g9f]], [[7g9g]], [[7g9h]], [[7g9i, [[7g9j]] – hGEF-H1 DH domain + RhoA + inhibitor<br />	+	**[[7g80]], [[7g81]], [[7g82]], [[7g83]], [[7g84]], [[7g85]], [[7g86]], [[7g88]], [[7g89]], [[7g8a]], [[7g8b]], [[7g8c]], [[7g8d]], [[7g8e]], [[7g8f]], [[7g8g]], [[7g8h]], [[7g8i]], [[7g8j]], [[7g8k]], [[7g8l]], [[7g8m]], [[7g8n]], [[7g8o]], [[7g8p]], [[7g8q]], [[7g8r]], [[7g87]], [[7g8s]], [[7g8t]], [[7g8u]], [[7g8v]], [[7g8w]], [[7g8x]], [[7g8y]], [[7g8z]], [[7g90]], [[7g91]], [[7g92]], [[7g93]], [[7g94]], [[7g95]], [[7g96]], [[7g97]], [[7g98]], [[7g99]], [[7g9a]], [[7g9b]], [[7g9c]], [[7g9d]], [[7g9e]], [[7g9f]], [[7g9g]], [[7g9h]], [[7g9i]], [[7g9j]] – hGEF-H1 DH domain + RhoA + inhibitor<br />
	**[[5efx]] – hGEF-H1 439-582 <br />		**[[5efx]] – hGEF-H1 439-582 <br />

Michal Harel at 10:08, 16 October 2023

Michal Harel — Mon, 16 Oct 2023 10:08:27 GMT

←Older revision		Revision as of 10:08, 16 October 2023
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	**[[3p6a]] – hGEF DH/PH domain (mutant)<br />		**[[3p6a]] – hGEF DH/PH domain (mutant)<br />
	**[[1shz]], [[3ab3]] – hGEF N terminal RGS domain + guanine nucleotide-binding protein<br />		**[[1shz]], [[3ab3]] – hGEF N terminal RGS domain + guanine nucleotide-binding protein<br />
		+
		+	*GEF guanine nucleotide exchange factor 2
		+
		+	**[[8bnt]] – hGEF-H1 DH domain 206-448 + RhoA <br />
		+	**[[7g80]], [[7g81]], [[7g82]], [[7g83]], [[7g84]], [[7g85]], [[7g86]], [[7g88]], [[7g89]], [[7g8a]], [[7g8b]], [[7g8c]], [[7g8d]], [[7g8e]], [[7g8f]], [[7g8g]], [[7g8h]], [[7g8i]], [[7g8j]], [[7g8k]], [[7g8l]], [[7g8m]], [[7g8n]], [[7g8o]], [[7g8p]], [[7g8q]], [[7g8r]], [[7g87]], [[7g8s]], [[7g8t]], [[7g8u]], [[7g8v]], [[7g8w]], [[7g8x]], [[7g8y]], [[7g8z]], [[7g90]], [[7g91]], [[7g92]], [[7g93]], [[7g94]], [[7g95]], [[7g96]], [[7g97]], [[7g98]], [[7g99]], [[7g9a]], [[7g9b]], [[7g9c]], [[7g9d]], [[7g9e]], [[7g9f]], [[7g9g]], [[7g9h]], [[7g9i, [[7g9j]] – hGEF-H1 DH domain + RhoA + inhibitor<br />
		+	**[[5efx]] – hGEF-H1 439-582 <br />

	*GEF guanine nucleotide exchange factor 3		*GEF guanine nucleotide exchange factor 3
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	**[[2dx1]] – hGEF 59-540<br />		**[[2dx1]] – hGEF 59-540<br />
	**[[2pz1]] – hGEF 137-599<br />		**[[2pz1]] – hGEF 137-599<br />
		+	**[[3nmx]], [[3nmz]] – hGEF 170-276 + APC<br />

	*GEF guanine nucleotide exchange factor 6		*GEF guanine nucleotide exchange factor 6
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	**[[2dls]] – hGEF PDZ domain 44-123 - NMR<br />		**[[2dls]] – hGEF PDZ domain 44-123 - NMR<br />
		+	**[[5e6p]] – hGEF PDZ domain + plexin-B2 <br />
	**[[3kz1]], [[3t06]] – hGEF DH/PH domain 710-1085 + transforming protein GEFA <br />		**[[3kz1]], [[3t06]] – hGEF DH/PH domain 710-1085 + transforming protein GEFA <br />
		+	**[[5jhg]] – hGEF DH/PH domain + transforming protein RhoA <br />
		+	**[[5jhh]] – hGEF DH/PH domain + transforming protein RhoA + inhibitor<br />
	**[[1xcg]] – hGEF DH/PH domain + transforming protein GEFA - NMR<br />		**[[1xcg]] – hGEF DH/PH domain + transforming protein GEFA - NMR<br />
-	**[[3cx6]] – rGEF RGS domain 307-508 + guanine nucleotide-binding protein <br />	+	**[[3cx6]], [[3cx8]] – rGEF RGS domain 307-508 + guanine nucleotide-binding protein <br />

	*GEF guanine nucleotide exchange factor 12 (Leukemia-associated GEFGEF)		*GEF guanine nucleotide exchange factor 12 (Leukemia-associated GEFGEF)
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	**[[6bcb]] – mGEF 302-444 + transforming protein RhoA<br />		**[[6bcb]] – mGEF 302-444 + transforming protein RhoA<br />
		+
		+	*GEF guanine nucleotide exchange factor 25
		+
		+	**[[2rgn]] – hGEF 149-502 + transforming protein RhoA + guanine nucleotide-binding protein G(I)<br />

	*GEF guanine nucleotide exchange factor 28		*GEF guanine nucleotide exchange factor 28

Michal Harel at 09:48, 16 February 2022

Michal Harel — Wed, 16 Feb 2022 09:48:44 GMT

←Older revision		Revision as of 09:48, 16 February 2022
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	**[[2os6]] – hGEF PDZ domain + plexin peptide – NMR<br />		**[[2os6]] – hGEF PDZ domain + plexin peptide – NMR<br />

-	*GEF guanine nucleotide exchange factor 16	+	*GEF guanine nucleotide exchange factor 16 (Ephexin-4)

	**[[1x6b]] – hGEF SH3 domain 334-399 - NMR<br />		**[[1x6b]] – hGEF SH3 domain 334-399 - NMR<br />
		+	**[[7cso]], [[7csp]], [[7csr]] – mGEF 261-713 (mutant)<br />

	*GEF guanine nucleotide exchange factor 18		*GEF guanine nucleotide exchange factor 18

Michal Harel at 09:37, 22 October 2020

Michal Harel — Thu, 22 Oct 2020 09:37:43 GMT

←Older revision		Revision as of 09:37, 22 October 2020
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	{{#tree:id=OrganizedByTopic\|openlevels=0\|		{{#tree:id=OrganizedByTopic\|openlevels=0\|

-	*~~Rho~~ guanine nucleotide exchange factor 1 (P115-~~RhoGEF~~)	+	*GEF guanine nucleotide exchange factor 1 (P115-GEFGEF)

-	**[[1iap]] – hGEF N terminal - human<br />	+	**[[1iap]] – hGEF N terminal RGS domain 42-252 - human<br />
-	**[[3odo]], [[3odw]], [[3odx]] – hGEF DH/PH domain <br />	+	**[[3odo]], [[3odw]], [[3odx]] – hGEF DH/PH domain 353-766<br />
	**[[3p6a]] – hGEF DH/PH domain (mutant)<br />		**[[3p6a]] – hGEF DH/PH domain (mutant)<br />
-	**[[1shz]], [[3ab3]] – hGEF N terminal + guanine nucleotide-binding protein<br />	+	**[[1shz]], [[3ab3]] – hGEF N terminal RGS domain + guanine nucleotide-binding protein<br />

-	*~~Rho~~ guanine nucleotide exchange factor 2	+	*GEF guanine nucleotide exchange factor 3

-	**[[~~5efx~~]] - ~~hGEF residues 439-582~~<br />	+	**[[2z0q]] – mGEF DH/PH domain - mouse<br />

-	*~~Rho~~ guanine nucleotide exchange factor 4 (Asef)	+	*GEF guanine nucleotide exchange factor 4 (Asef)

-	**[[2dx1~~]], [[2pz1~~]] – hGEF <br />	+	**[[2dx1]] – hGEF 59-540<br />
-	**[[~~3nmx]], [[3nmz~~]] – hGEF ~~+ APC variant protein~~<br />	+	**[[2pz1]] – hGEF 137-599<br />

-	*~~Rho~~ guanine nucleotide exchange factor 6	+	*GEF guanine nucleotide exchange factor 6

-	**[[1ujy]] – hGEF SH3 domain - NMR<br />	+	**[[1ujy]] – hGEF SH3 domain 160-222 - NMR<br />
-	**[[1wyr]] – hGEF CH domain - NMR<br />	+	**[[1wyr]] – hGEF CH domain 4-111 - NMR<br />

-	*~~Rho~~ guanine nucleotide exchange factor 7 (β-PIX)	+	*GEF guanine nucleotide exchange factor 7 (b-PIX)

-	**[[1by1]] – hGEF DH domain - NMR<br />	+	**[[1by1]] – hGEF DH domain 81-289 - NMR<br />
-	**[[2l3g]] – hGEF CH domain - NMR<br />	+	**[[2l3g]] – hGEF CH domain 1-137 - NMR<br />
-	**[[2esw]] – ~~GEF~~ SH3 domain ~~– mouse~~<br />	+	**[[2esw]] – mGEF SH3 domain 7-63 <br />
	**[[2g6f]] – rGEF SH3 domain – rat<br />		**[[2g6f]] – rGEF SH3 domain – rat<br />
-	**[[2w6b]] – rGEF coiled-coil domain <br />	+	**[[2w6b]] – rGEF coiled-coil domain 588-638 <br />

-	*~~Rho~~ guanine nucleotide exchange factor 7 complex with peptide	+	*GEF guanine nucleotide exchange factor 7 complex with peptide

	**[[2ak5]] – hGEF SH3 domain + CBL-b peptide <br />		**[[2ak5]] – hGEF SH3 domain + CBL-b peptide <br />
	**[[2df6]] – hGEF SH3 domain + PAK-1 peptide <br />		**[[2df6]] – hGEF SH3 domain + PAK-1 peptide <br />
	**[[1zsg]] – hGEF residues 179-243 + PAK-1 peptide – NMR<br />		**[[1zsg]] – hGEF residues 179-243 + PAK-1 peptide – NMR<br />
-	**[[5sxp]] - hGEF residues 183-243 + E3 ubiquitin-protein ligase itchy<br />
	**[[2p4r]] – rGEF SH3 domain + E3 ubiquitin protein ligase peptide <br />		**[[2p4r]] – rGEF SH3 domain + E3 ubiquitin protein ligase peptide <br />
	**[[3l4f]] – rGEF coiled-coil domain + SHANK1 PDZ domain <br />		**[[3l4f]] – rGEF coiled-coil domain + SHANK1 PDZ domain <br />

-	*~~Rho~~ guanine nucleotide exchange factor 8 (PRONE8)	+	*GEF guanine nucleotide exchange factor 8 (PRONE8)

	**[[3eo2]] – hGEF residues 161-373 <br />		**[[3eo2]] – hGEF residues 161-373 <br />
-	**[[4xh9]] – hGEF DH/PH domain + transforming protein ~~RhoA~~ <br />	+	**[[4xh9]] – hGEF DH/PH domain + transforming protein GEFA <br />
-	**[[2ntx]] – AtGEF PRONE domain – ''Arabidopasis thaliana''<br />	+	**[[2ntx]] – AtGEF PRONE domain 76-440 – Arabidopasis thaliana<br />
	**[[2wbl]] – AtGEF PRONE domain + GTPase ROP7 <br />		**[[2wbl]] – AtGEF PRONE domain + GTPase ROP7 <br />
	**[[2nty]] – AtGEF PRONE domain + GTPase ROP4 + GDP <br />		**[[2nty]] – AtGEF PRONE domain + GTPase ROP4 + GDP <br />

-	*~~Rho~~ guanine nucleotide exchange factor 9 (collybistin)	+	*GEF guanine nucleotide exchange factor 9 (collybistin)

	**[[2ysq]] – hGEF SH3 domain - NMR<br />		**[[2ysq]] – hGEF SH3 domain - NMR<br />
	**[[4mt6]], [[4mt7]] – rGEF (mutant)<br />		**[[4mt6]], [[4mt7]] – rGEF (mutant)<br />
-	**[[2dfk]] – rGEF + CDC42 <br />	+	**[[2dfk]] – rGEF II + CDC42 <br />

-	*~~Rho~~ guanine nucleotide exchange factor 11	+	*GEF guanine nucleotide exchange factor 11

-	**[[2dls]] – hGEF PDZ domain - NMR~~<br />~~	+	**[[2dls]] – hGEF PDZ domain 44-123 - NMR<br />
-	**[[5tyt]] - hGEF PDZ domain/CXCR2 peptide<br />	+	**[[3kz1]], [[3t06]] – hGEF DH/PH domain 710-1085 + transforming protein GEFA <br />
-	**[[3kz1]], [[3t06~~]], [[5jhg]], [[5jhh~~]] – hGEF DH/PH domain + transforming protein ~~RhoA~~ <br />	+	**[[1xcg]] – hGEF DH/PH domain + transforming protein GEFA - NMR<br />
-	**[[1xcg]] – hGEF DH/PH domain + transforming protein ~~RhoA~~ - NMR<br />	+	**[[3cx6]] – rGEF RGS domain 307-508 + guanine nucleotide-binding protein <br />
-	**[[3cx6]] – rGEF RGS domain + guanine nucleotide-binding protein ~~<br />~~	+
-	**[[5e6p]] - mGEF PDZ domain + plexin-B2<br />	+

-	*~~Rho~~ guanine nucleotide exchange factor 12 (Leukemia-associated ~~RhoGEF~~)	+	*GEF guanine nucleotide exchange factor 12 (Leukemia-associated GEFGEF)

-	**[[1txd]] – hGEF DH/PH domain <br />	+	**[[1txd]] – hGEF DH/PH domain 764-1138<br />
-	**[[2omj]] – hGEF PDZ domain <br />	+	**[[2omj]] – hGEF PDZ domain 67-151<br />
-	**[[1x86]] – hGEF DH/PH domain (mutant) + transforming protein ~~RhoA~~ <br />	+	**[[1x86]] – hGEF DH/PH domain (mutant) + transforming protein GEFA <br />
	**[[2os6]] – hGEF PDZ domain + plexin peptide – NMR<br />		**[[2os6]] – hGEF PDZ domain + plexin peptide – NMR<br />

-	*~~Rho~~ guanine nucleotide exchange factor 16	+	*GEF guanine nucleotide exchange factor 16

-	**[[1x6b]] – hGEF SH3 domain - NMR<br />	+	**[[1x6b]] – hGEF SH3 domain 334-399 - NMR<br />

	*GEF guanine nucleotide exchange factor 18		*GEF guanine nucleotide exchange factor 18

-	**[[6bcb]] – mGEF + transforming protein RhoA<br />	+	**[[6bcb]] – mGEF 302-444 + transforming protein RhoA<br />

	*GEF guanine nucleotide exchange factor 28		*GEF guanine nucleotide exchange factor 28

-	**[[6bc1]] – hGEF + Ras-related C3 botulinum toxin substrate 1<br />	+	**[[6bc1]] – hGEF PH domain 1049-1194 + Ras-related C3 botulinum toxin substrate 1<br />
-	**[[6bc0]] – hGEF + transforming protein RhoA<br />	+	**[[6bc0]] – hGEF PH domain + transforming protein RhoA<br />
		+
	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel: New page: == 3D Structures of Rho guanine nucleotide exchange factor == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Rho ...

Michal Harel — Sun, 15 Dec 2019 10:35:25 GMT

New page: == 3D Structures of Rho guanine nucleotide exchange factor == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Rho ...

New page

== 3D Structures of Rho guanine nucleotide exchange factor ==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*Rho guanine nucleotide exchange factor 1 (P115-RhoGEF)

**[[1iap]] – hGEF N terminal - human 
**[[3odo]], [[3odw]], [[3odx]] – hGEF DH/PH domain 
**[[3p6a]] – hGEF DH/PH domain (mutant) 
**[[1shz]], [[3ab3]] – hGEF N terminal + guanine nucleotide-binding protein 

*Rho guanine nucleotide exchange factor 2

**[[5efx]] - hGEF residues 439-582 

*Rho guanine nucleotide exchange factor 4 (Asef)

**[[2dx1]], [[2pz1]] – hGEF 
**[[3nmx]], [[3nmz]] – hGEF + APC variant protein 

*Rho guanine nucleotide exchange factor 6

**[[1ujy]] – hGEF SH3 domain - NMR 
**[[1wyr]] – hGEF CH domain - NMR 

*Rho guanine nucleotide exchange factor 7 (β-PIX)

**[[1by1]] – hGEF DH domain - NMR 
**[[2l3g]] – hGEF CH domain - NMR 
**[[2esw]] – GEF SH3 domain – mouse 
**[[2g6f]] – rGEF SH3 domain – rat 
**[[2w6b]] – rGEF coiled-coil domain 

*Rho guanine nucleotide exchange factor 7 complex with peptide

**[[2ak5]] – hGEF SH3 domain + CBL-b peptide 
**[[2df6]] – hGEF SH3 domain + PAK-1 peptide 
**[[1zsg]] – hGEF residues 179-243 + PAK-1 peptide – NMR 
**[[5sxp]] - hGEF residues 183-243 + E3 ubiquitin-protein ligase itchy 
**[[2p4r]] – rGEF SH3 domain + E3 ubiquitin protein ligase peptide 
**[[3l4f]] – rGEF coiled-coil domain + SHANK1 PDZ domain 

*Rho guanine nucleotide exchange factor 8 (PRONE8)

**[[3eo2]] – hGEF residues 161-373 
**[[4xh9]] – hGEF DH/PH domain + transforming protein RhoA 
**[[2ntx]] – AtGEF PRONE domain – ''Arabidopasis thaliana'' 
**[[2wbl]] – AtGEF PRONE domain + GTPase ROP7 
**[[2nty]] – AtGEF PRONE domain + GTPase ROP4 + GDP 

*Rho guanine nucleotide exchange factor 9 (collybistin)

**[[2ysq]] – hGEF SH3 domain - NMR 
**[[4mt6]], [[4mt7]] – rGEF (mutant) 
**[[2dfk]] – rGEF + CDC42 

*Rho guanine nucleotide exchange factor 11

**[[2dls]] – hGEF PDZ domain - NMR 
**[[5tyt]] - hGEF PDZ domain/CXCR2 peptide 
**[[3kz1]], [[3t06]], [[5jhg]], [[5jhh]] – hGEF DH/PH domain + transforming protein RhoA 
**[[1xcg]] – hGEF DH/PH domain + transforming protein RhoA - NMR 
**[[3cx6]] – rGEF RGS domain + guanine nucleotide-binding protein 
**[[5e6p]] - mGEF PDZ domain + plexin-B2 

*Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)

**[[1txd]] – hGEF DH/PH domain 
**[[2omj]] – hGEF PDZ domain 
**[[1x86]] – hGEF DH/PH domain (mutant) + transforming protein RhoA 
**[[2os6]] – hGEF PDZ domain + plexin peptide – NMR 

*Rho guanine nucleotide exchange factor 16

**[[1x6b]] – hGEF SH3 domain - NMR 

*GEF guanine nucleotide exchange factor 18

**[[6bcb]] – mGEF + transforming protein RhoA 

*GEF guanine nucleotide exchange factor 28

**[[6bc1]] – hGEF + Ras-related C3 botulinum toxin substrate 1 
**[[6bc0]] – hGEF + transforming protein RhoA 
}}

[[Category:Topic Page]]