Ribosomal protein L10 - Revision history

Michal Harel at 08:46, 27 February 2022

Michal Harel — Sun, 27 Feb 2022 08:46:23 GMT

←Older revision		Revision as of 08:46, 27 February 2022
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	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

-	[[3jsy]] – RPL10 N-terminal – ''Methanocaldocoddus jannaschii''<br />
	[[2pa2]] – RPL10 core domain – human<br />		[[2pa2]] – RPL10 core domain – human<br />
	[[1zav]], [[1zaw]], [[1zax]] – RPL10+RPL7 N-terminal – ''Thermotoga maritima''<br />		[[1zav]], [[1zaw]], [[1zax]] – RPL10+RPL7 N-terminal – ''Thermotoga maritima''<br />
-	[[3a1y]] - RPL10 N-terminal+RPL12 – ''Pyrococcus horikoshii''	+	[[3a1y]] - RPL10 N-terminal+RPL12 – ''Pyrococcus horikoshii''<br />
		+	[[3jsy]] – MjRPL10 N-terminal – ''Methanocaldocoddus jannaschii''<br />
		+	[[5d6g]] – MjRPL10 + 23S RNA<br />
		+	[[5dar]] – MjRPL10 + RPL11 + 23S RNA<br />
		+	[[5d8h]] – MjRPL10 + RPL11 + 23S RNA + thiostrepton<br />

	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Joel L. Sussman at 06:31, 1 October 2017

Joel L. Sussman — Sun, 01 Oct 2017 06:31:28 GMT

←Older revision		Revision as of 06:31, 1 October 2017
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-	<StructureSection load='' size='350' side='right' scene='' caption='Human ribosomal protein L10 core domain complex with K+ ion (PDB code [[2pa2]])'>	+	<StructureSection load='2pa2' size='350' side='right' scene='' caption='Human ribosomal protein L10 core domain complex with K+ ion (PDB code [[2pa2]])'>
	== Function ==		== Function ==
	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.		[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.

Joel L. Sussman at 06:31, 1 October 2017

Joel L. Sussman — Sun, 01 Oct 2017 06:31:17 GMT

←Older revision		Revision as of 06:31, 1 October 2017
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-	<StructureSection load='~~2pa2~~' size='350' side='right' scene='' caption='Human ribosomal protein L10 core domain complex with K+ ion (PDB code [[2pa2]])'>	+	<StructureSection load='' size='350' side='right' scene='' caption='Human ribosomal protein L10 core domain complex with K+ ion (PDB code [[2pa2]])'>
	== Function ==		== Function ==
	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.		[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.

Michal Harel at 18:19, 29 September 2017

Michal Harel — Fri, 29 Sep 2017 18:19:19 GMT

←Older revision		Revision as of 18:19, 29 September 2017
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-		+	<StructureSection load='2pa2' size='350' side='right' scene='' caption='Human ribosomal protein L10 core domain complex with K+ ion (PDB code [[2pa2]])'>
-	<StructureSection load='2pa2' size='350' side='right' scene='' caption='Human ribosomal protein L10 core domain (PDB code [[2pa2]])'>	+
	== Function ==		== Function ==
	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.		[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.

Michal Harel at 18:18, 29 September 2017

Michal Harel — Fri, 29 Sep 2017 18:18:24 GMT

←Older revision		Revision as of 18:18, 29 September 2017
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-	~~{{STRUCTURE_2xg0\| PDB~~=~~2xg0 \| SIZE~~=~~300\| SCENE~~=~~Ribosomal_protein_L10/Cv/1 \|~~right~~\|CAPTION~~=~~Ribosomal protein L10 from~~ ''~~Thermus thermophilus'~~' [[~~2xg0~~]]~~, chain J }}~~	+
		+	<StructureSection load='2pa2' size='350' side='right' scene='' caption='Human ribosomal protein L10 core domain (PDB code [[2pa2]])'>
	== Function ==		== Function ==
	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.		[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.
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	== Relevance ==		== Relevance ==
	Mutation in RPL10 causes X-linked intellectual disability and cerebellar hypoplasia<ref>PMID:26290468</ref>.		Mutation in RPL10 causes X-linked intellectual disability and cerebellar hypoplasia<ref>PMID:26290468</ref>.
-		+	</StructureSection>
	== 3D Structures of Ribosomal protein L10 ==		== 3D Structures of Ribosomal protein L10 ==

Michal Harel at 08:16, 14 August 2016

Michal Harel — Sun, 14 Aug 2016 08:16:03 GMT

←Older revision		Revision as of 08:16, 14 August 2016
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	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-
-	===Ribosomal protein L10 ===

	[[3jsy]] – RPL10 N-terminal – ''Methanocaldocoddus jannaschii''<br />		[[3jsy]] – RPL10 N-terminal – ''Methanocaldocoddus jannaschii''<br />
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	[[3a1y]] - RPL10 N-terminal+RPL12 – ''Pyrococcus horikoshii''		[[3a1y]] - RPL10 N-terminal+RPL12 – ''Pyrococcus horikoshii''

-		+	== References ==
		+	<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 08:14, 14 August 2016

Michal Harel — Sun, 14 Aug 2016 08:14:45 GMT

←Older revision		Revision as of 08:14, 14 August 2016
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	{{STRUCTURE_2xg0\| PDB=2xg0 \| SIZE=300\| SCENE=Ribosomal_protein_L10/Cv/1 \|right\|CAPTION=Ribosomal protein L10 from ''Thermus thermophilus'' [[2xg0]], chain J }}		{{STRUCTURE_2xg0\| PDB=2xg0 \| SIZE=300\| SCENE=Ribosomal_protein_L10/Cv/1 \|right\|CAPTION=Ribosomal protein L10 from ''Thermus thermophilus'' [[2xg0]], chain J }}
		+	== Function ==
		+	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome<ref>PMID:23886624</ref>. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.

-	~~[[Ribosomal protein L10]] (~~RPL10~~) is one of the 34 proteins which belong to the~~ <~~scene name='Ribosomal_protein_L10/Cv/2'~~>~~large 50S subunit~~</~~scene~~> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.	+	== Relevance ==
		+	Mutation in RPL10 causes X-linked intellectual disability and cerebellar hypoplasia<ref>PMID:26290468</ref>.

	== 3D Structures of Ribosomal protein L10 ==		== 3D Structures of Ribosomal protein L10 ==

Michal Harel at 10:57, 9 December 2014

Michal Harel — Tue, 09 Dec 2014 10:57:35 GMT

←Older revision		Revision as of 10:57, 9 December 2014
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-
	{{STRUCTURE_2xg0\| PDB=2xg0 \| SIZE=300\| SCENE=Ribosomal_protein_L10/Cv/1 \|right\|CAPTION=Ribosomal protein L10 from ''Thermus thermophilus'' [[2xg0]], chain J }}		{{STRUCTURE_2xg0\| PDB=2xg0 \| SIZE=300\| SCENE=Ribosomal_protein_L10/Cv/1 \|right\|CAPTION=Ribosomal protein L10 from ''Thermus thermophilus'' [[2xg0]], chain J }}

	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.		[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.
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	== 3D Structures of Ribosomal protein L10 ==		== 3D Structures of Ribosomal protein L10 ==

Michal Harel at 08:51, 9 December 2014

Michal Harel — Tue, 09 Dec 2014 08:51:32 GMT

←Older revision		Revision as of 08:51, 9 December 2014
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-	~~[[Image:RPL10.png\|left\|200px\|thumb\|Crystal Structure of Ribosomal protein L10 from ''Thermus thermophilus'' ([[2xg0]], chain J)]]~~	+
	{{STRUCTURE_2xg0\| PDB=2xg0 \| SIZE=300\| SCENE=Ribosomal_protein_L10/Cv/1 \|right\|CAPTION=Ribosomal protein L10 from ''Thermus thermophilus'' [[2xg0]], chain J }}		{{STRUCTURE_2xg0\| PDB=2xg0 \| SIZE=300\| SCENE=Ribosomal_protein_L10/Cv/1 \|right\|CAPTION=Ribosomal protein L10 from ''Thermus thermophilus'' [[2xg0]], chain J }}

-	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E~~. The images at the left and at the right correspond to one representative RPL10, ''i.e.'' the crystal structure of Ribosomal protein L10 from ''Thermus thermophilus'' ([[2xg0]], chain J)~~.	+	[[Ribosomal protein L10]] (RPL10) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L10/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is found mostly in eubacteria. The L10 forms a complex with a dimer of L7/L12. This complex is called L8. The acidic ribosomal protein P0 is the equivalent of the 50S L10 and the 60S L10E.

	{{TOC limit\|limit=2}}		{{TOC limit\|limit=2}}
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-	=== ~~RPL10~~ ===	+	===Ribosomal protein L10 ===

	[[3jsy]] – RPL10 N-terminal – ''Methanocaldocoddus jannaschii''<br />		[[3jsy]] – RPL10 N-terminal – ''Methanocaldocoddus jannaschii''<br />

Michal Harel at 08:06, 24 April 2014

Michal Harel — Thu, 24 Apr 2014 08:06:22 GMT

←Older revision		Revision as of 08:06, 24 April 2014
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	[[3a1y]] - RPL10 N-terminal+RPL12 – ''Pyrococcus horikoshii''		[[3a1y]] - RPL10 N-terminal+RPL12 – ''Pyrococcus horikoshii''

-	=== L10 in 50S subunit+RNA ===
-
-	[[2xg0]], [[2xg2]], [[3kir]], [[3kit]], [[3kiw]], [[3kiy]], [[4byc]], [[4bye]] – TtRPL10 in 50S subunit+RNA fragments - ''Thermus thermophilus''<br />
-	[[2x9s]], [[2x9u]], [[2wrj]], [[2wrl]], [[2wro]], [[2wrr]], [[2wh2]], [[2wh4]], [[2j01]], [[2j03]], [[3mrz]], [[3ms1]], [[3i8i]], [[3d5b]], [[3d5d]], [[2xqe]], [[2y0v]], [[2y0x]], [[2y0z]], [[2y11]], [[2y13]], [[2y15]], [[2y17]], [[2y19]], [[3pyo]], [[3pyr]], [[3pyt]], [[3pyv]], [[3zvp]], [[3zn9]], [[3zne]], [[4b8g]], [[4b8i]], [[4jux]], [[4k0m]], [[4k0q]], [[4kbu]], [[4kbw]], [[4kcz]], [[4kd2]], [[4kd9]], [[4kdb]], [[4kdh]], [[4kdk]], [[4abs]] - TtRPL10 in 50S subunit+5S RRNA+23S RRNA<br />
-	[[1kqs]], [[1qvg]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+CCA - ''Haloarcula marismortui''<br />
-	[[1jj2]], [[1ffk]], [[3cc2]], [[2qa4]], [[1s72]], [[4hub]], [[3ow2]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA<br />
-	[[3cc7]], [[3cce]], [[3ccj]], [[3ccl]], [[3ccm]], [[3ccq]], [[3ccr]], [[3ccs]], [[3ccu]], [[3ccv]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA (mutant)<br />
-	[[1yj9]] - HmRPL10P in 50S subunit (L22 mutant)+5S RRNA+23S RRNA<br />
-	[[1vq4]], [[1vq5]], [[1vq7]], [[1vql]], [[1vqm]], [[1vqp]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+transition state analog<br />
-	[[1vq6]], [[1vqk]], [[1vqn]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+ c-hpmn+CCA-Phe-caproic acid-biotin<br />
-	[[1q86]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+CCA-Phe-caproic acid-biotin<br />
-	[[1vqo]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+ CCPMN<br />
-	[[1qvf]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA + deacylated tRNA minihelix<br />
-	[[3j0t]], [[3j0w]], [[3j0y]], [[3j11]], [[3j12]], [[3j14]] – EcRPL10 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM – ''Escherichia coli''<br />
-	[[3uos]], [[3sgf]], [[3j37]], [[4kix]], [[4kiz]], [[4kj1]], [[4kj3]], [[4kj5]], [[4kj7]], [[4kj9]] - EcRPL10 in 50S subunit+5S RRNA+23S RRNA<br />
-	[[3j21]] – RPL10 in 50S subunit + P0 + LX – ''Pyrococcus furiosus'' – Cryo EM<br />
-
-	=== L10 in 50S subunit + antibiotics ===
-
-	[[1k73]], [[1kc8]], [[1k8a]], [[1k9m]], [[1kd1]], [[1m1k]], [[3i55]], [[3i56]], [[3g4s]], [[3g6e]], [[3g71]], [[2qex]], [[3cpw]], [[3cc4]], [[3cd6]], [[2otj]], [[2otl]], [[1yit]], [[1q7y]], [[1q81]], [[1q82]], [[1n8r]], [[1nji]], [[3cxc]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+antibiotic - ''Halobacterium marismortui''<br />
-	[[1yhq]], [[1yi2]], [[1yij]], [[1yjn]], [[1yjw]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA (mutant)+antibiotic<br />
-	[[1m90]], [[3cma]], [[3cme]], [[1vq8]], [[1vq9]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+ sparsomycin+CCA-Phe-caproic acid-biotin
-
-	=== L10 in 60S subunit ===
-
-	[[3jyw]] - RPL10 in 60S subunit – ''Thermomyces lanuginosus'' – Cryo-EM<br />
-	[[3j39]] – RPL10 in 60S subunit – ''Drosophila melanogaster'' – Cryo-EM<br />
-	[[1s1i]] - yRPL10 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast<br />
-	[[3izs]] – yRPL10 in 60S ribosomal subunit – Cryo-EM<br />
-	[[3u5e]], [[3u5i]] – yRPL10 in 60S ribosomal subuni<br />
-	[[3o58]], [[3o5h]] – yRPL10 in 60S ribosomal subunit+25S RRNA+5S RRNA+5.8S RRNA<br />
-	[[3izr]] – RPL10 in 60S subunit – wheat – Cryo EM<br />
-	[[4b6a]] – yRPL10 in 60S ribosomal subunit + P0 + P1 + P2 + ARX1 – Cryo-EM<br />
-	[[4a17]], [[4a1a]], [[4a1c]], [[4a1e]] - RPL10 in 60S ribosomal subunit+25S RRNA+5S RRNA+5.8S RRNA + P0 - ''Tetrahymena thermophila''<br />
-	[[3j16]] – yRPL10 + yRPL6 + yRPL11 + yRPS6 + yRPS24 + yRPS30+18S RRNA + 28S RRNA + P-site tRNA + RLI1P + DOM34P – Cryo-EM
-
-	=== L10 in large + small ribosomal subunit ===
-
-	[[2zkr]] - RPL10 in 60S ribosomal subunit+30S ribosomal subunit+28S RRNA+5.8S RRNA – Cryo-EM – dog<br />
-	[[3j0l]] - rRPL10 in 60S ribosomal subunit+40S ribosomal subunit+RRNA fragments+ mRNA fragments – Cryo-EM – rabbit<br />
-	[[3j0o]], [[3j0p]], [[3j0q]] - rRPL10 in 60S ribosomal subunit+40S ribosomal subunit+RRNA fragments+ mRNA fragments + tRNA – Cryo-EM<br />
-
-	=== L10 in 50S subunit + various proteins ===
-
-	[[1w2b]] - HmRPL10P in 50S subunit+5S RRNA+23S RRNA+trigger factor N-terminal

	[[Category:Topic Page]]		[[Category:Topic Page]]