Rivaroxaban - Revision history

Alexander Berchansky at 12:40, 20 February 2024

Alexander Berchansky — Tue, 20 Feb 2024 12:40:18 GMT

←Older revision		Revision as of 12:40, 20 February 2024
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	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>		<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
-	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. See also [https://en.wikipedia.org/wiki/Rivaroxaban Rivaroxaban].	+	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an [[Anticoagulants\|anticoagulant medication]] (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. See also [https://en.wikipedia.org/wiki/Rivaroxaban Rivaroxaban].

	<scene name='95/954035/Cv/5'>Rivaroxaban binding site</scene>. See also [[Apixaban]].		<scene name='95/954035/Cv/5'>Rivaroxaban binding site</scene>. See also [[Apixaban]].

Alexander Berchansky at 13:12, 27 August 2023

Alexander Berchansky — Sun, 27 Aug 2023 13:12:49 GMT

←Older revision		Revision as of 13:12, 27 August 2023
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	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>		<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
-	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/5'>Rivaroxaban binding site</scene>. See also [[Apixaban]].	+	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. See also [https://en.wikipedia.org/wiki/Rivaroxaban Rivaroxaban].
		+
		+	<scene name='95/954035/Cv/5'>Rivaroxaban binding site</scene>. See also [[Apixaban]].

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 11:45, 1 March 2023

Alexander Berchansky — Wed, 01 Mar 2023 11:45:00 GMT

←Older revision		Revision as of 11:45, 1 March 2023
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	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>		<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
-	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/5'>Rivaroxaban binding site</scene>.	+	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/5'>Rivaroxaban binding site</scene>. See also [[Apixaban]].

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 16:09, 28 February 2023

Alexander Berchansky — Tue, 28 Feb 2023 16:09:18 GMT

←Older revision		Revision as of 16:09, 28 February 2023
Line 1:		Line 1:
	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>		<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
-	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/4'>Rivaroxaban binding site</scene>.	+	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/5'>Rivaroxaban binding site</scene>.

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 16:05, 28 February 2023

Alexander Berchansky — Tue, 28 Feb 2023 16:05:46 GMT

←Older revision		Revision as of 16:05, 28 February 2023
Line 1:		Line 1:
	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>		<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
-	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound Factor Xa in the prothrombinase complex. It is a selective direct [[factor Xa]] inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of [[Factor Xa]] interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/4'>Rivaroxaban binding site</scene>.	+	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound [[Factor Xa]] in the prothrombinase complex. It is a selective direct factor Xa inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/4'>Rivaroxaban binding site</scene>.

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 16:05, 28 February 2023

Alexander Berchansky — Tue, 28 Feb 2023 16:05:01 GMT

←Older revision		Revision as of 16:05, 28 February 2023
Line 1:		Line 1:
	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>		<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
-	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound Factor Xa in the prothrombinase complex. It is a selective direct [[factor Xa]] inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of [[Factor Xa]] interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi~~. Rivaroxaban does not inhibit thrombin (activated Factor II), and no effects on platelets have been demonstrated~~. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed.	+	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound Factor Xa in the prothrombinase complex. It is a selective direct [[factor Xa]] inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of [[Factor Xa]] interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed. <scene name='95/954035/Cv/4'>Rivaroxaban binding site</scene>.

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 12:41, 28 February 2023

Alexander Berchansky — Tue, 28 Feb 2023 12:41:03 GMT

←Older revision		Revision as of 12:41, 28 February 2023
Line 1:		Line 1:
	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>		<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
-	Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots.	+	<scene name='95/954035/Cv/2'>Rivaroxaban</scene>, sold under the brand name '''Xarelto''' among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. Rivaroxaban inhibits both free and bound Factor Xa in the prothrombinase complex. It is a selective direct [[factor Xa]] inhibitor with an onset of action of 2.5 to 4 hours. Inhibition of [[Factor Xa]] interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. Rivaroxaban does not inhibit thrombin (activated Factor II), and no effects on platelets have been demonstrated. It allows predictable anticoagulation and dose adjustments and routine coagulation monitoring; dietary restrictions are not needed.

	</StructureSection>		</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Alexander Berchansky at 11:48, 27 February 2023

Alexander Berchansky — Mon, 27 Feb 2023 11:48:40 GMT

←Older revision		Revision as of 11:48, 27 February 2023
Line 1:		Line 1:
-	<StructureSection load='5vof' size='~~340~~' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene=''>	+	<StructureSection load='5vof' size='350' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene='95/954035/Cv/1'>
	Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots.		Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots.

Alexander Berchansky: New page: Rivaroxaban, sold under the brand name Xarelto among others,...

Alexander Berchansky — Mon, 27 Feb 2023 11:45:19 GMT

New page: <StructureSection load='5vof' size='340' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene=''> Rivaroxaban, sold under the brand name Xarelto among others,...

New page

<StructureSection load='5vof' size='340' side='right' caption='DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban' scene=''>
Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots.

</StructureSection>
== References ==
<references/>