Rotation of 4 degrees of FIX - Revision history

David Canner at 15:30, 1 October 2010

David Canner — Fri, 01 Oct 2010 15:30:43 GMT

←Older revision		Revision as of 15:30, 1 October 2010
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	==Additional Resources==		==Additional Resources==
-	For additional information, see: [[~~Diabetes & Hypoglycemia~~]]	+	For additional information, see: [[Hemophilia]]
	<br />		<br />

	== References ==		== References ==
	<references/>		<references/>

David Canner at 15:30, 1 October 2010

David Canner — Fri, 01 Oct 2010 15:30:32 GMT

←Older revision		Revision as of 15:30, 1 October 2010
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	Movement of A chain of IX-bp caused by induced fitting and of IXGD1–46 caused by Mg2+ ions <ref>PMID:12695512</ref>. A, interaction patch for IX-bp (residues 100–110 of IX-bp B chain) is overlaid. Complexed and uncomplexed IX-bp A and B chains are shown in red and green for A and in blue and green for B, respectively. B, hydrophobic and hydrophilic interactions involving Lys22 of IXGD1–46 and Thr62, Lys63, and Glu108 of IX-bp A chain resulting from the movement of the A chain. The surface model was calculated using GRASP (41). This interaction was not observed, formed under Mg2+-free condition. C, Mg2+-bound IXGD1–46/IX-bp complex is shown in red and green, and the Mg2+-free (Ca2+ only) complex is depicted by yellow ribbon representation. Both structures are superimposed as a result of the position of C atoms of IX-bp.		Movement of A chain of IX-bp caused by induced fitting and of IXGD1–46 caused by Mg2+ ions <ref>PMID:12695512</ref>. A, interaction patch for IX-bp (residues 100–110 of IX-bp B chain) is overlaid. Complexed and uncomplexed IX-bp A and B chains are shown in red and green for A and in blue and green for B, respectively. B, hydrophobic and hydrophilic interactions involving Lys22 of IXGD1–46 and Thr62, Lys63, and Glu108 of IX-bp A chain resulting from the movement of the A chain. The surface model was calculated using GRASP (41). This interaction was not observed, formed under Mg2+-free condition. C, Mg2+-bound IXGD1–46/IX-bp complex is shown in red and green, and the Mg2+-free (Ca2+ only) complex is depicted by yellow ribbon representation. Both structures are superimposed as a result of the position of C atoms of IX-bp.

		+	==Additional Resources==
		+	For additional information, see: [[Diabetes & Hypoglycemia]]
		+	<br />

	== References ==		== References ==
	<references/>		<references/>

Nadia Dorochko at 22:58, 26 April 2009

Nadia Dorochko — Sun, 26 Apr 2009 22:58:46 GMT

←Older revision		Revision as of 22:58, 26 April 2009
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-	Movement of A chain of IX-bp caused by induced fitting and of IXGD1–46 caused by Mg2+ ions. A, interaction patch for IX-bp (residues 100–110 of IX-bp B chain) is overlaid. Complexed and uncomplexed IX-bp A and B chains are shown in red and green for A and in blue and green for B, respectively. B, hydrophobic and hydrophilic interactions involving Lys22 of IXGD1–46 and Thr62, Lys63, and Glu108 of IX-bp A chain resulting from the movement of the A chain. The surface model was calculated using GRASP (41). This interaction was not observed, formed under Mg2+-free condition. C, Mg2+-bound IXGD1–46/IX-bp complex is shown in red and green, and the Mg2+-free (Ca2+ only) complex is depicted by yellow ribbon representation. Both structures are superimposed as a result of the position of C atoms of IX-bp.	+	Movement of A chain of IX-bp caused by induced fitting and of IXGD1–46 caused by Mg2+ ions <ref>PMID:12695512</ref>. A, interaction patch for IX-bp (residues 100–110 of IX-bp B chain) is overlaid. Complexed and uncomplexed IX-bp A and B chains are shown in red and green for A and in blue and green for B, respectively. B, hydrophobic and hydrophilic interactions involving Lys22 of IXGD1–46 and Thr62, Lys63, and Glu108 of IX-bp A chain resulting from the movement of the A chain. The surface model was calculated using GRASP (41). This interaction was not observed, formed under Mg2+-free condition. C, Mg2+-bound IXGD1–46/IX-bp complex is shown in red and green, and the Mg2+-free (Ca2+ only) complex is depicted by yellow ribbon representation. Both structures are superimposed as a result of the position of C atoms of IX-bp.
		+
		+
		+	== References ==
		+	<references/>

Nadia Dorochko at 22:34, 26 April 2009

Nadia Dorochko — Sun, 26 Apr 2009 22:34:50 GMT

←Older revision		Revision as of 22:34, 26 April 2009
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	[[Image:glaIonsP4A.jpg]]		[[Image:glaIonsP4A.jpg]]
		+
		+
		+
		+	Movement of A chain of IX-bp caused by induced fitting and of IXGD1–46 caused by Mg2+ ions. A, interaction patch for IX-bp (residues 100–110 of IX-bp B chain) is overlaid. Complexed and uncomplexed IX-bp A and B chains are shown in red and green for A and in blue and green for B, respectively. B, hydrophobic and hydrophilic interactions involving Lys22 of IXGD1–46 and Thr62, Lys63, and Glu108 of IX-bp A chain resulting from the movement of the A chain. The surface model was calculated using GRASP (41). This interaction was not observed, formed under Mg2+-free condition. C, Mg2+-bound IXGD1–46/IX-bp complex is shown in red and green, and the Mg2+-free (Ca2+ only) complex is depicted by yellow ribbon representation. Both structures are superimposed as a result of the position of C atoms of IX-bp.

Nadia Dorochko: New page: Image:glaIonsP4A.jpg

Nadia Dorochko — Sun, 26 Apr 2009 22:33:29 GMT

New page: Image:glaIonsP4A.jpg

New page

[[Image:glaIonsP4A.jpg]]