Sandbox Reserved 1357 - Revision history

Student at 20:25, 28 February 2018

Student — Wed, 28 Feb 2018 20:25:44 GMT

←Older revision		Revision as of 20:25, 28 February 2018
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	== Structure ==		== Structure ==
-	1aoi is a complex that connects the nucleosome core particle and DNA fragment. It is considered a heterodecamer (10 chains). It has 5 macromolecules: 4 histones and 1 palindromic 146 bp DNA repeat organized in a super helix around the histones from the human X chromosome. The 4 histones are H2B,H4,H2A,H3. Nucleosomes are subunits of chromosomes. They are formed when the DNA wraps around the histones, resembling tiny “beads” all throughout the compact chromatin.	+	1aoi is a complex that connects the nucleosome core particle and DNA fragment. It is considered a heterodecamer (10 chains). It has 5 macromolecules: 4 histones and 1 palindromic 146 bp DNA repeat organized in a super helix around the histones from the human X chromosome. The 4 histones are H2B,H4,H2A,H3. Nucleosomes are subunits of chromosomes. They are formed when the DNA wraps around the histones, resembling tiny “beads” all throughout the compact chromatin. There a millions and millions of nucleosomes scattered throughout our DNA ensuring that chromatin is packed tightly around the histones.

	<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />		<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />

-	<scene name='77/777677/Alpha_carbons/1'>Alpha carbons</scene> are shown in purple.	+	<scene name='77/777677/Alpha_carbons/1'>Alpha carbons</scene> are shown in purple in the middle of the molecule. These make up the heterodecamer structure of the molecule.

-	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.	+	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein. This is just a snapshot of one section of DNA.

-	There are 6 manganese <scene name='77/777677/Ligands/3'>ligands</scene> shown in green.	+	There are 6 manganese <scene name='77/777677/Ligands/3'>ligands</scene> bound to the protein shown in green scattered throughout the molecule.

	== Function ==		== Function ==

Student at 21:23, 21 February 2018

Student — Wed, 21 Feb 2018 21:23:35 GMT

←Older revision		Revision as of 21:23, 21 February 2018
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	1aoi. (2017, August 9). Retrieved February 21, 2018, from http://proteopedia.org/wiki/index.php/1aoiHistone		1aoi. (2017, August 9). Retrieved February 21, 2018, from http://proteopedia.org/wiki/index.php/1aoiHistone
		+
	H2B 1.1. (2018, January 31). Retrieved February 21, 2018, from http://www.uniprot.org/uniprot/P02281		H2B 1.1. (2018, January 31). Retrieved February 21, 2018, from http://www.uniprot.org/uniprot/P02281
		+
	Luger, K., Richmond, R. K., Mader, A. W., & Sargent, D. F. (1997, January 01).		Luger, K., Richmond, R. K., Mader, A. W., & Sargent, D. F. (1997, January 01).
		+
	COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT. Retrieved February 21, 2018, from http://www.ebi.ac.uk/pdbe/entry/pdb/1aoi		COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT. Retrieved February 21, 2018, from http://www.ebi.ac.uk/pdbe/entry/pdb/1aoi
		+
	Nucleosome/Nucleosomes. (n.d.). Retrieved February 21, 2018, from https://www.nature.com/scitable/definition/nucleosome-nucleosomes-30		Nucleosome/Nucleosomes. (n.d.). Retrieved February 21, 2018, from https://www.nature.com/scitable/definition/nucleosome-nucleosomes-30
	<references/>		<references/>

Student at 21:23, 21 February 2018

Student — Wed, 21 Feb 2018 21:23:06 GMT

←Older revision		Revision as of 21:23, 21 February 2018
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	== References ==		== References ==
		+
		+	1aoi. (2017, August 9). Retrieved February 21, 2018, from http://proteopedia.org/wiki/index.php/1aoiHistone
		+	H2B 1.1. (2018, January 31). Retrieved February 21, 2018, from http://www.uniprot.org/uniprot/P02281
		+	Luger, K., Richmond, R. K., Mader, A. W., & Sargent, D. F. (1997, January 01).
		+	COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT. Retrieved February 21, 2018, from http://www.ebi.ac.uk/pdbe/entry/pdb/1aoi
		+	Nucleosome/Nucleosomes. (n.d.). Retrieved February 21, 2018, from https://www.nature.com/scitable/definition/nucleosome-nucleosomes-30
	<references/>		<references/>

Student at 21:11, 21 February 2018

Student — Wed, 21 Feb 2018 21:11:27 GMT

←Older revision		Revision as of 21:11, 21 February 2018
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	<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />		<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />

-	<scene name='77/777677/Alpha_carbons/1'>Alpha ~~Ccarbons~~</scene> are shown in purple.	+	<scene name='77/777677/Alpha_carbons/1'>Alpha carbons</scene> are shown in purple.

	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.		<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.

Student at 21:11, 21 February 2018

Student — Wed, 21 Feb 2018 21:11:00 GMT

←Older revision		Revision as of 21:11, 21 February 2018
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	== Structure ==		== Structure ==
-	1aoi is a complex that connects the nucleosome core particle and DNA fragment. It is considered a heterodecamer (10 chains). It has 5 macromolecules: 4 histones and 1 palindromic 146 bp DNA repeat from the human X chromosome. The 4 histones are H2B,H4,H2A,H3. Nucleosomes are subunits of chromosomes. They are formed when the DNA wraps around the histones, resembling tiny “beads” all throughout the compact chromatin.	+	1aoi is a complex that connects the nucleosome core particle and DNA fragment. It is considered a heterodecamer (10 chains). It has 5 macromolecules: 4 histones and 1 palindromic 146 bp DNA repeat organized in a super helix around the histones from the human X chromosome. The 4 histones are H2B,H4,H2A,H3. Nucleosomes are subunits of chromosomes. They are formed when the DNA wraps around the histones, resembling tiny “beads” all throughout the compact chromatin.

	<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />		<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />

-	<scene name='77/777677/Alpha_carbons/1'>~~alpha carbons~~</scene> are shown in purple.	+	<scene name='77/777677/Alpha_carbons/1'>Alpha Ccarbons</scene> are shown in purple.

	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.		<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.
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	== Function ==		== Function ==
-	The complex is a core nucleosome. The protein acts as a transcription regulator, repairs DNA, helps with DNA replication and chromosome remodeling.	+	The complex is a core nucleosome. The protein acts as a transcription regulator, repairs DNA, helps with DNA replication and chromosome remodeling. By winding the DNA around the histones, this complex makes DNA inaccessible for replication since the template strand is hidden. Because it prevents replication of DNA for various structures, complex, and processes, this protein not only regulates template dependent replication but also regulates transcription, DNA repair, and chromosomal stability. In order to make DNA accessible, the histones are phosphorylated.

	== References ==		== References ==
	<references/>		<references/>

Student at 21:05, 21 February 2018

Student — Wed, 21 Feb 2018 21:05:34 GMT

←Older revision		Revision as of 21:05, 21 February 2018
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	<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />		<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />

-	<scene name='77/777677/Alpha_carbons/1'>~~Alpha Carbons~~</scene> are shown in purple.	+	<scene name='77/777677/Alpha_carbons/1'>alpha carbons</scene> are shown in purple.

	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.		<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.

-	There are 6 manganese <scene name='77/777677/Ligands/2'>~~Ligands~~</scene> shown in green.	+	There are 6 manganese <scene name='77/777677/Ligands/3'>ligands</scene> shown in green.

	== Function ==		== Function ==

Student at 21:03, 21 February 2018

Student — Wed, 21 Feb 2018 21:03:11 GMT

←Older revision		Revision as of 21:03, 21 February 2018
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	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.		<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.

-	<scene name='77/777677/Ligands/1'>Ligands</scene>	+	There are 6 manganese <scene name='77/777677/Ligands/2'>Ligands</scene> shown in green.

	== Function ==		== Function ==

Student at 20:59, 21 February 2018

Student — Wed, 21 Feb 2018 20:59:11 GMT

←Older revision		Revision as of 20:59, 21 February 2018
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	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.		<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.
		+
		+	<scene name='77/777677/Ligands/1'>Ligands</scene>

	== Function ==		== Function ==

Student at 20:54, 21 February 2018

Student — Wed, 21 Feb 2018 20:54:24 GMT

←Older revision		Revision as of 20:54, 21 February 2018
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	== Structure ==		== Structure ==
-	~~Heterodecamer structure containing ten subunits~~. ~~The protein~~ has ~~four distinct polypeptide molecules which are~~ histones~~, including~~ palindromic 146 BP. The ~~complex also contains one distinct~~ DNA ~~molecule~~.	+	1aoi is a complex that connects the nucleosome core particle and DNA fragment. It is considered a heterodecamer (10 chains). It has 5 macromolecules: 4 histones and 1 palindromic 146 bp DNA repeat from the human X chromosome. The 4 histones are H2B,H4,H2A,H3. Nucleosomes are subunits of chromosomes. They are formed when the DNA wraps around the histones, resembling tiny “beads” all throughout the compact chromatin.

	<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />		<Structure load='1aoi' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />

	<scene name='77/777677/Alpha_carbons/1'>Alpha Carbons</scene> are shown in purple.		<scene name='77/777677/Alpha_carbons/1'>Alpha Carbons</scene> are shown in purple.
-	<scene name='77/777677/Dna/3'>DNA</scene>	+
		+	<scene name='77/777677/Dna/3'>DNA</scene> is shown in purple and surrounds the protein.

	== Function ==		== Function ==

Student at 20:52, 21 February 2018

Student — Wed, 21 Feb 2018 20:52:23 GMT

←Older revision		Revision as of 20:52, 21 February 2018
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	<scene name='77/777677/Alpha_carbons/1'>Alpha Carbons</scene> are shown in purple.		<scene name='77/777677/Alpha_carbons/1'>Alpha Carbons</scene> are shown in purple.
-		+	<scene name='77/777677/Dna/3'>DNA</scene>
-	<scene name='77/777677/Dna/2'>DNA</scene>	+

	== Function ==		== Function ==