Michal Harel: New page: Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Son of sevenless 1; Domains - HD histone domain 1-191; DH Dbl homol...

Michal Harel — Tue, 21 Nov 2023 09:50:51 GMT

New page: Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Son of sevenless 1; Domains - HD histone domain 1-191; DH Dbl homol...

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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*Son of sevenless 1; Domains - HD histone domain 1-191; DH Dbl homology 203-389; PH pleckstrin homology 443-548; REM+catalytic 601-1020

**[[3ksy]] - hSOS1 - human 
**[[1q9c]] - hSOS1 HD 
**[[1awe]] - hSOS1 PH - NMR 
**[[2ii0]] - hSOS1 REM+catalytic domains 
**[[1dbh]] - hSOS1 DH+PH domains 
**[[1xd4]], [[1xdv]] - hSOS1 DH+PH+REM+catalytic domains 
**[[1pms]] - mSOS1 PH (mutant) - mouse - NMR 

*Son of sevenless 1 complex

**[[1bkd]] - hSOS1 REM+catalytic domains + HRas 
**[[1xd2]] - hSOS1 REM+catalytic domains + HRas + GDP 

*Son of sevenless 1 homolog REM+catalytic domains

**[[5ovd]] - hSOS1 (mutant) 
**[[6scm]], [[6sfr]], [[7avi]], [[7avl]], [[7avs]], [[7avt]], [[7avu]], [[7avv]], [[7avs]], [[7ukr]], [[7uks]] - hSOS1 + inhibitor 
**[[5ove]], [[5ovg]], [[5ovf]] [[5ovi]], [[5ovh]] - hSOS1 (mutant) + inhibitor 
**[[8be2]] - hSOS1 + nanobody 
**[[1nvx]], [[1nvu]] - hSOS1 + HRas + GTP 
**[[1nvw]], [[1nvv]] - hSOS1 + HRas + GNP 
**[[4uru]], [[4urv]], [[4urw]], [[4urx]], [[4ury]], [[4urz]], [[4us0]], [[4us1]], [[4us2]] - hSOS1 + HRas + ligand 
**[[8be6]], [[8be7]], [[8be8]], [[8be9]], [[8bea]] - hSOS1 + HRas + peptidomimetic 
**[[4nym]], [[6bvi]], [[6bvk]], [[6bvj]], [[6bvm]], [[6bvl]], [[6cuo]], [[6cup]], [[6cur]], [[6d55]], [[6d56]], [[6d59]], [[6d5e]], [[6d5g]], [[6d5h]], [[6d5j]], [[6d5l]], [[6d5w]], [[6d5v]], [[6d5m]], [[6v9o]] - hSOS1 + HRas + GNP + activator 
**[[4nyi]], [[4nyj]], [[5wfo]], [[5wfq]], [[5wfp]], [[5wfr]], [[6v94]], [[6v9j]], [[6v9l]], [[6v9n]], [[6v9m]], [[6v9f]] - hSOS1 + HRas + GNP + inhibitor 
**[[6epl]] - hSOS1 REM+catalytic domains (mutant) + KRas 
**[[8be4]], [[8be5]] - hSOS1 + KRas + nanobody 
**[[7kfz]] - hSOS1 + KRas + GNP – Cryo EM 
**[[6epn]], [[6epm]], [[6epp]], [[6epo]] - hSOS1 + KRas + inhibitor 

*Son of sevenless 2

**[[6eie]] - hSOS2 REM+catalytic domains (mutant) 
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Son of sevenless 3D structures - Revision history

Michal Harel: New page: Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Son of sevenless 1; Domains - HD histone domain 1-191; DH Dbl homol...