The Bacterial Flagellar Hook - Revision history

Eric Martz: /* See Also */

Eric Martz — Sat, 04 Sep 2021 22:23:18 GMT

Eric Martz at 22:22, 4 September 2021

Eric Martz — Sat, 04 Sep 2021 22:22:58 GMT

←Older revision		Revision as of 22:22, 4 September 2021
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	==See Also==		==See Also==
	* [[Flagella, bacterial]]		* [[Flagella, bacterial]]
		+	* [[User:Fadel A. Samatey/FlgE II/Complete Flagellar Hook Structure\|Cryo-EM structure of the complete flagellar hook of ''Campylobacter jejuni'' (2016)
	* [[User:Fadel A. Samatey/FlgE I\|X-ray structure of the hook monomers of ''Campylobacter jejuni'' and also of ''Caulobacter cresentus'']] (2016)		* [[User:Fadel A. Samatey/FlgE I\|X-ray structure of the hook monomers of ''Campylobacter jejuni'' and also of ''Caulobacter cresentus'']] (2016)
	* [[Flagellar filament of bacteria]]		* [[Flagellar filament of bacteria]]

Eric Martz: /* See Also */

Eric Martz — Sat, 04 Sep 2021 22:19:20 GMT

Michal Harel at 08:27, 2 January 2018

Michal Harel — Tue, 02 Jan 2018 08:27:37 GMT

←Older revision		Revision as of 08:27, 2 January 2018
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	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

-	[[1wlg]] – ~~StFLGE31~~ – ''Salmonella typhimurium''<br />	+	[[1wlg]] – StFlgE31 – ''Salmonella typhimurium''<br />
-	[[2bgy]], [[2bgz]] - ~~StFLGE31~~ residues 71-363 – Cryo EM<br />	+	[[2bgy]], [[2bgz]] - StFlgE31 residues 71-363 – Cryo EM<br />
-	[[3a69]] - ~~StFLGE31~~ – Cryo EM<br />	+	[[3a69]] - StFlgE31 – Cryo EM<br />
-	[[5jxl]] – ~~FLGE~~ – ''Campylobacter jejuni''<br />	+	[[5jxl]] – FlgE – ''Campylobacter jejuni''<br />
-	[[5ay6]] – ~~FLGE~~ – ''Caulobacter crescentus''<br />	+	[[5ay6]] – FlgE – ''Caulobacter crescentus''<br />

	==References and Notes==		==References and Notes==
	<references />		<references />
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 19:07, 19 October 2017

Michal Harel — Thu, 19 Oct 2017 19:07:25 GMT

←Older revision		Revision as of 19:07, 19 October 2017
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	==References and Notes==		==References and Notes==
	<references />		<references />
		+	[[Category:Topic Page]]

Michal Harel at 10:23, 16 May 2017

Michal Harel — Tue, 16 May 2017 10:23:26 GMT

←Older revision		Revision as of 10:23, 16 May 2017
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	[[2bgy]], [[2bgz]] - StFLGE31 residues 71-363 – Cryo EM<br />		[[2bgy]], [[2bgz]] - StFLGE31 residues 71-363 – Cryo EM<br />
	[[3a69]] - StFLGE31 – Cryo EM<br />		[[3a69]] - StFLGE31 – Cryo EM<br />
-	[[5jxl]] – FLGE – Campylobacter jejuni<br />	+	[[5jxl]] – FLGE – ''Campylobacter jejuni''<br />
-	[[5ay6]] – FLGE – Caulobacter crescentus<br />	+	[[5ay6]] – FLGE – ''Caulobacter crescentus''<br />

	==References and Notes==		==References and Notes==
	<references />		<references />

Michal Harel at 10:22, 16 May 2017

Michal Harel — Tue, 16 May 2017 10:22:33 GMT

←Older revision		Revision as of 10:22, 16 May 2017
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	[[1wlg]] – StFLGE31 – ''Salmonella typhimurium''<br />		[[1wlg]] – StFLGE31 – ''Salmonella typhimurium''<br />
	[[2bgy]], [[2bgz]] - StFLGE31 residues 71-363 – Cryo EM<br />		[[2bgy]], [[2bgz]] - StFLGE31 residues 71-363 – Cryo EM<br />
-	[[3a69]] - StFLGE31 – Cryo EM	+	[[3a69]] - StFLGE31 – Cryo EM<br />
		+	[[5jxl]] – FLGE – Campylobacter jejuni<br />
		+	[[5ay6]] – FLGE – Caulobacter crescentus<br />

	==References and Notes==		==References and Notes==
	<references />		<references />

Michal Harel at 09:47, 2 March 2016

Michal Harel — Wed, 02 Mar 2016 09:47:43 GMT

←Older revision		Revision as of 09:47, 2 March 2016
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	The '''bacterial flagellar hook''' described in this article is one part of the bacterial flagellum. Please see [[Flagella, bacterial]] for an overview of where the hook fits in the flagellum.		The '''bacterial flagellar hook''' described in this article is one part of the bacterial flagellum. Please see [[Flagella, bacterial]] for an overview of where the hook fits in the flagellum.
		+
		+	==Function==

	The flagellar hook is a molecular [http://en.wikipedia.org/wiki/Universal_joint universal joint] that transmits [http://en.wikipedia.org/wiki/Torque torque] from the motor, anchored in the bacterial cell wall, to the [[Flagellar filament of bacteria\|flagellar filament]], the relatively rigid helical rod that propels the bacterial cell when rotated. The hook is flexible: it enables the filament to adopt a wide range of angles relative to the motor axis and cell wall, yet continue to be rotated by the motor at all these angles.		The flagellar hook is a molecular [http://en.wikipedia.org/wiki/Universal_joint universal joint] that transmits [http://en.wikipedia.org/wiki/Torque torque] from the motor, anchored in the bacterial cell wall, to the [[Flagellar filament of bacteria\|flagellar filament]], the relatively rigid helical rod that propels the bacterial cell when rotated. The hook is flexible: it enables the filament to adopt a wide range of angles relative to the motor axis and cell wall, yet continue to be rotated by the motor at all these angles.

Michal Harel at 16:01, 22 January 2016

Michal Harel — Fri, 22 Jan 2016 16:01:31 GMT

←Older revision		Revision as of 16:01, 22 January 2016
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	===FlgE31 2004===		===FlgE31 2004===
-	<applet load='1wlg' size='~~400~~' frame='true' align='right' scene='The_Bacterial_Flagellar_Hook/1wlg_1_mmol/3' caption='Salmonella typhimurium flagellar hook protein FLGE [[1wlg]]'/>	+	<applet load='1wlg' size='350' frame='true' align='right' scene='The_Bacterial_Flagellar_Hook/1wlg_1_mmol/3' caption='Salmonella typhimurium flagellar hook protein FLGE [[1wlg]]'/>
	In 2004, Samatey ''et al.'' solved the structure of the mid-portion of the wild-type FlgE of ''Salmonella typhimurium'' by [[X-ray crystallography]] at a [[Resolution\|resolution]] of 1.8 Å ([[1wlg]])<ref name="hook1">PMID: 15510139</ref>. The fragment successfully crystallized, designated FlgE31, consisted of amino acids 71-369, of which 71-363 were resolved (72% of the full-length 402-residue protein). Removal of the ends of the full-length chain (domain D0, see below) was required in order to coax the protein to crystallize, instead of forming filaments.		In 2004, Samatey ''et al.'' solved the structure of the mid-portion of the wild-type FlgE of ''Salmonella typhimurium'' by [[X-ray crystallography]] at a [[Resolution\|resolution]] of 1.8 Å ([[1wlg]])<ref name="hook1">PMID: 15510139</ref>. The fragment successfully crystallized, designated FlgE31, consisted of amino acids 71-369, of which 71-363 were resolved (72% of the full-length 402-residue protein). Removal of the ends of the full-length chain (domain D0, see below) was required in order to coax the protein to crystallize, instead of forming filaments.

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	==Monomer Within the Hook==		==Monomer Within the Hook==
-	<applet size='~~400~~' frame='true' align='right' scene='The_Bacterial_Flagellar_Hook/Flagellar_hook_3rings_pdb_gz/3'/>	+	<applet size='350' frame='true' align='right' scene='The_Bacterial_Flagellar_Hook/Flagellar_hook_3rings_pdb_gz/3'/>
	From the curved model of the hook, here is a short segment just three Flg31 monomers long (<scene name='The_Bacterial_Flagellar_Hook/Flagellar_hook_3rings_pdb_gz/3'>restore initial scene</scene>). Each color represents one of the 11 protofilaments. Since each protofilament is 3 monomers in length, there are 33 monomers in this model. You can see how the Flg31 monomers fit into the hook when <scene name='The_Bacterial_Flagellar_Hook/Flagellar_hook_3rings_pdb_gz/2'>two monomers are highlighted</scene>.		From the curved model of the hook, here is a short segment just three Flg31 monomers long (<scene name='The_Bacterial_Flagellar_Hook/Flagellar_hook_3rings_pdb_gz/3'>restore initial scene</scene>). Each color represents one of the 11 protofilaments. Since each protofilament is 3 monomers in length, there are 33 monomers in this model. You can see how the Flg31 monomers fit into the hook when <scene name='The_Bacterial_Flagellar_Hook/Flagellar_hook_3rings_pdb_gz/2'>two monomers are highlighted</scene>.

Michal Harel at 08:37, 18 August 2014

Michal Harel — Mon, 18 Aug 2014 08:37:50 GMT

←Older revision		Revision as of 08:37, 18 August 2014
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-	The bacterial flagellar hook described in this article is one part of the bacterial flagellum. Please see [[Flagella, bacterial]] for an overview of where the hook fits in the flagellum.	+	The '''bacterial flagellar hook''' described in this article is one part of the bacterial flagellum. Please see [[Flagella, bacterial]] for an overview of where the hook fits in the flagellum.

	The flagellar hook is a molecular [http://en.wikipedia.org/wiki/Universal_joint universal joint] that transmits [http://en.wikipedia.org/wiki/Torque torque] from the motor, anchored in the bacterial cell wall, to the [[Flagellar filament of bacteria\|flagellar filament]], the relatively rigid helical rod that propels the bacterial cell when rotated. The hook is flexible: it enables the filament to adopt a wide range of angles relative to the motor axis and cell wall, yet continue to be rotated by the motor at all these angles.		The flagellar hook is a molecular [http://en.wikipedia.org/wiki/Universal_joint universal joint] that transmits [http://en.wikipedia.org/wiki/Torque torque] from the motor, anchored in the bacterial cell wall, to the [[Flagellar filament of bacteria\|flagellar filament]], the relatively rigid helical rod that propels the bacterial cell when rotated. The hook is flexible: it enables the filament to adopt a wide range of angles relative to the motor axis and cell wall, yet continue to be rotated by the motor at all these angles.

←Older revision		Revision as of 22:23, 4 September 2021
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	==See Also==		==See Also==
	* [[Flagella, bacterial]]		* [[Flagella, bacterial]]
-	* [[User:Fadel A. Samatey/FlgE II/Complete Flagellar Hook Structure\|Cryo-EM structure of the complete flagellar hook of ''Campylobacter jejuni'' (2016)	+	* [[User:Fadel A. Samatey/FlgE II/Complete Flagellar Hook Structure\|Cryo-EM structure of the complete flagellar hook of ''Campylobacter jejuni'']] (2016)
	* [[User:Fadel A. Samatey/FlgE I\|X-ray structure of the hook monomers of ''Campylobacter jejuni'' and also of ''Caulobacter cresentus'']] (2016)		* [[User:Fadel A. Samatey/FlgE I\|X-ray structure of the hook monomers of ''Campylobacter jejuni'' and also of ''Caulobacter cresentus'']] (2016)
	* [[Flagellar filament of bacteria]]		* [[Flagellar filament of bacteria]]

←Older revision		Revision as of 22:19, 4 September 2021
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	==See Also==		==See Also==
	* [[Flagella, bacterial]]		* [[Flagella, bacterial]]
		+	* [[User:Fadel A. Samatey/FlgE I\|X-ray structure of the hook monomers of ''Campylobacter jejuni'' and also of ''Caulobacter cresentus'']] (2016)
	* [[Flagellar filament of bacteria]]		* [[Flagellar filament of bacteria]]
	* [[Fadel A. Samatey Group]]		* [[Fadel A. Samatey Group]]