Tissue factor - Revision history

Michal Harel at 10:08, 26 February 2020

Michal Harel — Wed, 26 Feb 2020 10:08:12 GMT

←Older revision		Revision as of 10:08, 26 February 2020
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	*Tissue factor		*Tissue factor

-	**[[1a21]] – rTF extracellular domain – rabbit<br />
	**[[2hft]], [[1boy]], [[1tfh]] – hTF extracellular domain – human<br />		**[[2hft]], [[1boy]], [[1tfh]] – hTF extracellular domain – human<br />
		+	**[[1a21]] – rTF extracellular domain – rabbit<br />

	*Tissue factor binary complex		*Tissue factor binary complex

-	**[[1dan]], [[1j9c]], [[1w0y]], [[4ylq]], [[4z6a]], [[4zma]] – hTF extracellular domain + factor VIIA<br />	+	**[[1dan]], [[1j9c]], [[1w0y]], [[4ylq]], [[4z6a]], [[4zma]], [[6r2w]] – hTF extracellular domain + factor VIIA<br />
	**[[1o5d]] – hTF extracellular domain (mutant) + factor VIIA<br />		**[[1o5d]] – hTF extracellular domain (mutant) + factor VIIA<br />
	**[[1ahw]], [[1jps]], [[1uj3]], [[4m7l]], [[5w06]] – hTF extracellular domain + antibody<br />		**[[1ahw]], [[1jps]], [[1uj3]], [[4m7l]], [[5w06]] – hTF extracellular domain + antibody<br />

Alexander Berchansky at 13:36, 24 September 2019

Alexander Berchansky — Tue, 24 Sep 2019 13:36:17 GMT

←Older revision		Revision as of 13:36, 24 September 2019
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	== Relevance ==		== Relevance ==
	TF expression by cardiac myocytes is important to maintain heart hemostasis under normal and pathologic conditions<ref>PMID:17663739</ref>.		TF expression by cardiac myocytes is important to maintain heart hemostasis under normal and pathologic conditions<ref>PMID:17663739</ref>.
-	*<scene name='59/595166/Cv/2'>Human tissue factor complex with coagulation factor VIIa heavy chain, light chain and Ca+2 ion</scene> (PDB code [[1j9c]]).	+	*<scene name='59/595166/Cv/3'>Human tissue factor complex with coagulation factor VIIa heavy chain, light chain and Ca+2 ion</scene> (PDB code [[1j9c]]).
	</StructureSection>		</StructureSection>

Michal Harel at 22:24, 25 September 2018

Michal Harel — Tue, 25 Sep 2018 22:24:44 GMT

←Older revision		Revision as of 22:24, 25 September 2018
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-	<StructureSection load='' size='~~450~~' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>	+	<StructureSection load='' size='350' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>

	== Function ==		== Function ==

Joel L. Sussman at 05:41, 16 October 2017

Joel L. Sussman — Mon, 16 Oct 2017 05:41:22 GMT

←Older revision		Revision as of 05:41, 16 October 2017
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-	<StructureSection load='' size='~~340~~' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>	+	<StructureSection load='' size='450' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>

	== Function ==		== Function ==

Joel L. Sussman at 05:40, 16 October 2017

Joel L. Sussman — Mon, 16 Oct 2017 05:40:56 GMT

←Older revision		Revision as of 05:40, 16 October 2017
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-	<StructureSection load='' size='~~450~~' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>	+	<StructureSection load='' size='340' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>

	== Function ==		== Function ==

Joel L. Sussman at 05:39, 16 October 2017

Joel L. Sussman — Mon, 16 Oct 2017 05:39:20 GMT

←Older revision		Revision as of 05:39, 16 October 2017
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-	<StructureSection load='~~1j9c~~' size='~~340~~' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>	+	<StructureSection load='' size='450' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>

	== Function ==		== Function ==

Michal Harel at 19:02, 10 October 2017

Michal Harel — Tue, 10 Oct 2017 19:02:46 GMT

←Older revision		Revision as of 19:02, 10 October 2017
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	**[[1dan]], [[1j9c]], [[1w0y]], [[4ylq]], [[4z6a]], [[4zma]] – hTF extracellular domain + factor VIIA<br />		**[[1dan]], [[1j9c]], [[1w0y]], [[4ylq]], [[4z6a]], [[4zma]] – hTF extracellular domain + factor VIIA<br />
	**[[1o5d]] – hTF extracellular domain (mutant) + factor VIIA<br />		**[[1o5d]] – hTF extracellular domain (mutant) + factor VIIA<br />
-	**[[1ahw]], [[1jps]], [[1uj3]], [[4m7l]] – hTF extracellular domain + antibody<br />	+	**[[1ahw]], [[1jps]], [[1uj3]], [[4m7l]], [[5w06]] – hTF extracellular domain + antibody<br />

	*Tissue factor ternary complex with coagulation factor VIIa and inhibitor		*Tissue factor ternary complex with coagulation factor VIIa and inhibitor

Alexander Berchansky at 08:55, 22 June 2017

Alexander Berchansky — Thu, 22 Jun 2017 08:55:07 GMT

←Older revision		Revision as of 08:55, 22 June 2017
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-	<StructureSection load='1j9c' size='340' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (~~aqua~~) and Ca+2 ion (green) (PDB code [[~~2aer~~]]).' scene='59/595166/Cv/1'>	+	<StructureSection load='1j9c' size='340' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code [[1j9c]]).' scene='59/595166/Cv/1'>

	== Function ==		== Function ==
Line 9:		Line 9:
	== Relevance ==		== Relevance ==
	TF expression by cardiac myocytes is important to maintain heart hemostasis under normal and pathologic conditions<ref>PMID:17663739</ref>.		TF expression by cardiac myocytes is important to maintain heart hemostasis under normal and pathologic conditions<ref>PMID:17663739</ref>.
-		+	*<scene name='59/595166/Cv/2'>Human tissue factor complex with coagulation factor VIIa heavy chain, light chain and Ca+2 ion</scene> (PDB code [[1j9c]]).
	</StructureSection>		</StructureSection>

Alexander Berchansky at 08:49, 22 June 2017

Alexander Berchansky — Thu, 22 Jun 2017 08:49:32 GMT

←Older revision		Revision as of 08:49, 22 June 2017
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-	<StructureSection load='1j9c' size='340' side='right' caption='Structure of human tissue factor (~~dark~~ green) complex with coagulation factor VIIa heavy chain (~~red~~) and light chain (aqua) and Ca+2 ion (green) (PDB code [[2aer]]).' scene=''>	+	<StructureSection load='1j9c' size='340' side='right' caption='Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (aqua) and Ca+2 ion (green) (PDB code [[2aer]]).' scene='59/595166/Cv/1'>

	== Function ==		== Function ==

Michal Harel at 10:11, 14 September 2016

Michal Harel — Wed, 14 Sep 2016 10:11:02 GMT

←Older revision		Revision as of 10:11, 14 September 2016
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	TF expression by cardiac myocytes is important to maintain heart hemostasis under normal and pathologic conditions<ref>PMID:17663739</ref>.		TF expression by cardiac myocytes is important to maintain heart hemostasis under normal and pathologic conditions<ref>PMID:17663739</ref>.

-	== Structural highlights ==
	</StructureSection>		</StructureSection>