Tyrosine phosphatase - Revision history

Michal Harel at 09:54, 30 December 2020

Michal Harel — Wed, 30 Dec 2020 09:54:07 GMT

←Older revision		Revision as of 09:54, 30 December 2020
Line 1:		Line 1:
	<StructureSection load='3i7z' size='340' side='right' caption='Human tyrosine phosphatase 1B catalytic domain (grey) complex with EGFR peptide (in green), VO4, glycerol, Tris, 2-amino-2-hydroxymethyl-1,3-diol, [[3i7z]]' scene='' >		<StructureSection load='3i7z' size='340' side='right' caption='Human tyrosine phosphatase 1B catalytic domain (grey) complex with EGFR peptide (in green), VO4, glycerol, Tris, 2-amino-2-hydroxymethyl-1,3-diol, [[3i7z]]' scene='' >
-	'''Tyrosine phosphatase''' (PTP) is an enzyme which removes phosphate from phosphorylated tyrosine residues. It is a key regulatory component of signal transduction pathways<ref>PMID:14625689</ref>. PTPs are divided to 4 subfamilies. '''PTP class I''' contains receptor PTPs (RPTP) and dual-specificity PTP which removes phosphate from Ser/Thr and tyrosine. Human '''PTP PRL''' is found in regenerating liver. '''PTP class II''' are low ~~moleculat~~ weight PTP which dephosphorylate a number of growth factors and modulate their signalling processes<ref>PMID:27421795</ref>. '''PTP class III''' contains CDC25 which removes phosphate from Thr and tyrosine. PTP containing SH2 domains are called PTP SHP. '''Non-receptor type PTPs''' are coded by the PTPN genes. <br />For details on ''Yersinia'' PTP see [[Yersinia YopH]].<br />For details of PTP complex with inhibitor see [[Student Projects for UMass Chemistry 423 Spring 2012-9]].	+	'''Tyrosine phosphatase''' (PTP) is an enzyme which removes phosphate from phosphorylated tyrosine residues. It is a key regulatory component of signal transduction pathways<ref>PMID:14625689</ref>. PTPs are divided to 4 subfamilies. '''PTP class I''' contains receptor PTPs (RPTP) and dual-specificity PTP which removes phosphate from Ser/Thr and tyrosine. Human '''PTP PRL''' is found in regenerating liver. '''PTP class II''' are low molecular weight PTP which dephosphorylate a number of growth factors and modulate their signalling processes<ref>PMID:27421795</ref>. '''PTP class III''' contains CDC25 which removes phosphate from Thr and tyrosine. PTP containing SH2 domains are called PTP SHP. '''Non-receptor type PTPs''' are coded by the PTPN genes. <br />For details on ''Yersinia'' PTP see [[Yersinia YopH]].<br />For details of PTP complex with inhibitor see [[Student Projects for UMass Chemistry 423 Spring 2012-9]].

	== Disease ==		== Disease ==

Michal Harel at 09:53, 30 December 2020

Michal Harel — Wed, 30 Dec 2020 09:53:33 GMT

←Older revision		Revision as of 09:53, 30 December 2020
Line 1:		Line 1:
	<StructureSection load='3i7z' size='340' side='right' caption='Human tyrosine phosphatase 1B catalytic domain (grey) complex with EGFR peptide (in green), VO4, glycerol, Tris, 2-amino-2-hydroxymethyl-1,3-diol, [[3i7z]]' scene='' >		<StructureSection load='3i7z' size='340' side='right' caption='Human tyrosine phosphatase 1B catalytic domain (grey) complex with EGFR peptide (in green), VO4, glycerol, Tris, 2-amino-2-hydroxymethyl-1,3-diol, [[3i7z]]' scene='' >
-	'''Tyrosine phosphatase''' (PTP) is an enzyme which removes phosphate from phosphorylated tyrosine residues. It is a key regulatory component of signal transduction pathways<ref>PMID:14625689</ref>. PTPs are divided to 4 subfamilies. '''PTP class I''' contains receptor PTPs (RPTP) and dual-specificity PTP which removes phosphate from Ser/Thr and tyrosine. '''PTP class II''' are low moleculat weight PTP which dephosphorylate a number of growth factors and modulate their signalling processes<ref>PMID:27421795</ref>. '''PTP class III''' contains CDC25 which removes phosphate from Thr and tyrosine. PTP containing SH2 domains are called PTP SHP. '''Non-receptor type PTPs''' are coded by the PTPN genes. <br />For details on ''Yersinia'' PTP see [[Yersinia YopH]].<br />For details of PTP complex with inhibitor see [[Student Projects for UMass Chemistry 423 Spring 2012-9]].	+	'''Tyrosine phosphatase''' (PTP) is an enzyme which removes phosphate from phosphorylated tyrosine residues. It is a key regulatory component of signal transduction pathways<ref>PMID:14625689</ref>. PTPs are divided to 4 subfamilies. '''PTP class I''' contains receptor PTPs (RPTP) and dual-specificity PTP which removes phosphate from Ser/Thr and tyrosine. Human '''PTP PRL''' is found in regenerating liver. '''PTP class II''' are low moleculat weight PTP which dephosphorylate a number of growth factors and modulate their signalling processes<ref>PMID:27421795</ref>. '''PTP class III''' contains CDC25 which removes phosphate from Thr and tyrosine. PTP containing SH2 domains are called PTP SHP. '''Non-receptor type PTPs''' are coded by the PTPN genes. <br />For details on ''Yersinia'' PTP see [[Yersinia YopH]].<br />For details of PTP complex with inhibitor see [[Student Projects for UMass Chemistry 423 Spring 2012-9]].

	== Disease ==		== Disease ==

Michal Harel at 09:15, 17 March 2020

Michal Harel — Tue, 17 Mar 2020 09:15:38 GMT

(Difference between revisions)

Michal Harel at 09:14, 17 March 2020

Michal Harel — Tue, 17 Mar 2020 09:14:42 GMT

(Difference between revisions)

Michal Harel at 23:03, 1 October 2018

Michal Harel — Mon, 01 Oct 2018 23:03:24 GMT

←Older revision		Revision as of 23:03, 1 October 2018
Line 81:		Line 81:
	**[[3nfk]], [[3nfl]], [[5eyz]], [[5ez0]] - hPTPN4 PDZ domain + peptide<br />		**[[3nfk]], [[3nfl]], [[5eyz]], [[5ez0]] - hPTPN4 PDZ domain + peptide<br />
	**[[2yu7]], [[2rmx]] – hPTPN6 SH2 domain + peptide – NMR<BR />		**[[2yu7]], [[2rmx]] – hPTPN6 SH2 domain + peptide – NMR<BR />
-	**[[4gs0]] – hPTPN6 catalytic domain + peptide<br />	+	**[[4gs0]], [[1fpr]] – hPTPN6 catalytic domain + peptide<br />
	**[[3d42]], [[3d44]] – hPTPN7 catalytic domain (mutant) + peptide<br />		**[[3d42]], [[3d44]] – hPTPN7 catalytic domain (mutant) + peptide<br />
	**[[4icz]] – hPTPN9 catalytic domain + peptide<br />		**[[4icz]] – hPTPN9 catalytic domain + peptide<br />
Line 94:		Line 94:
	**[[5lm2]] – hRPTP23 residues 362-713 + UBAP-1 peptide<br />		**[[5lm2]] – hRPTP23 residues 362-713 + UBAP-1 peptide<br />
	**[[3rz2]] - rPTP 4A1 + peptide<br />		**[[3rz2]] - rPTP 4A1 + peptide<br />
-	**[[1fpr]] - hPTP SHP-1 catalytic domain + peptide<br />
	**[[1aya]], [[1ayb]], [[1ayc]], [[1ayd]] – mPTP Syp N terminal SH2 domain + peptide<br />		**[[1aya]], [[1ayb]], [[1ayc]], [[1ayd]] – mPTP Syp N terminal SH2 domain + peptide<br />
	**[[1vj6]] – mPTP PDZ2 domain + APC C terminal – NMR<br />		**[[1vj6]] – mPTP PDZ2 domain + APC C terminal – NMR<br />
Line 132:		Line 131:
	**[[2b4s]] - hPTP1B catalytic domain + insulin receptor<br />		**[[2b4s]] - hPTP1B catalytic domain + insulin receptor<br />
	**[[2gph]] - hPTPN7 catalytic domain (mutant) + MAPK2<br />		**[[2gph]] - hPTPN7 catalytic domain (mutant) + MAPK2<br />
-	**[[1g4u]] – StPTP + RAS-related C3 botulinum toxin substrate <br />
-	**[[1jyo]] – StPTP + secretion chaperone SICP<br />
	**[[4je4]], [[4jeg]] – hPTPN11 catalytic domain + monobody<br />		**[[4je4]], [[4jeg]] – hPTPN11 catalytic domain + monobody<br />
-	**[[5lxq]] – mPTP + CNNM2<br />
	**[[5k25]], [[5k24]], [[5k23]] – hPTP PRL-2 + CNNM3<br />		**[[5k25]], [[5k24]], [[5k23]] – hPTP PRL-2 + CNNM3<br />
	**[[5k22]] – hPTP PRL-2 (mutant) + CNNM3<br />		**[[5k22]] – hPTP PRL-2 (mutant) + CNNM3<br />
	**[[5tsr]] – hPTP PRL-3 (mutant) + CNNM3<br />		**[[5tsr]] – hPTP PRL-3 (mutant) + CNNM3<br />
		+	**[[1g4u]] – StPTP + RAS-related C3 botulinum toxin substrate <br />
		+	**[[1jyo]] – StPTP + secretion chaperone SICP<br />
		+	**[[5lxq]] – mPTP + CNNM2<br />
	**[[5mmz]] – mPTP 4A1 + CNNM2<br />		**[[5mmz]] – mPTP 4A1 + CNNM2<br />
	**[[4zj7]] – yPTPN CDC14 C terminal + importin<br />		**[[4zj7]] – yPTPN CDC14 C terminal + importin<br />
Line 166:		Line 165:
	**[[1jln]], [[2a8b]] - mRPTP-R catalytic domain<br />		**[[1jln]], [[2a8b]] - mRPTP-R catalytic domain<br />
	**[[3sr9]] - mRPTP-σ residues 1326 – 1901<br />		**[[3sr9]] - mRPTP-σ residues 1326 – 1901<br />
-	**[[2nv5]] – ~~RPRP - rat~~<br />	+	**[[2nv5]] – rRPRP<br />
	**[[2yd4]] - cRPTP-σ Ig1-2 domain – chicken<br />		**[[2yd4]] - cRPTP-σ Ig1-2 domain – chicken<br />
	**[[2yd1]], [[2yd2]], [[3pxj]] – DmRPTP Ig1-2 domain – ''Drosophila melanogaster''<br />		**[[2yd1]], [[2yd2]], [[3pxj]] – DmRPTP Ig1-2 domain – ''Drosophila melanogaster''<br />
Line 176:		Line 175:
	**[[2i3r]], [[2i5x]] - hRPTP-β catalytic domain<br />		**[[2i3r]], [[2i5x]] - hRPTP-β catalytic domain<br />
	**[[2hc1]], [[2hc2]] - hRPTP-β catalytic domain (mutant) <br />		**[[2hc1]], [[2hc2]] - hRPTP-β catalytic domain (mutant) <br />
-	**[[2h4v]], [[2pbn]] – hRPTP-γ domain 1<br />	+	**[[2h4v]], [[2pbn]], [[3qcb]] – hRPTP-γ domain 1<br />
	**[[3qcn]] - hRPTP-γ domain 1 (mutant) <br />		**[[3qcn]] - hRPTP-γ domain 1 (mutant) <br />
	**[[2nlk]] - hRPTP-γ catalytic domain<br />		**[[2nlk]] - hRPTP-γ catalytic domain<br />
Line 219:		Line 218:
	**[[2h02]], [[2h04]], [[2i3u]], [[2i4e]], [[2i4g]], [[2i4h]] - hRPTP-β catalytic domain + inhibitor<br />		**[[2h02]], [[2h04]], [[2i3u]], [[2i4e]], [[2i4g]], [[2i4h]] - hRPTP-β catalytic domain + inhibitor<br />
	**[[2h03]] - hRPTP-β catalytic domain (mutant) + inhibitor<br />		**[[2h03]] - hRPTP-β catalytic domain (mutant) + inhibitor<br />
-	**[[2hy3~~]], [[3qcb~~]], [[3qcc]], [[3qcd]] - hRPTP-γ domain 1 + VO4<BR />	+	**[[2hy3]], [[3qcc]], [[3qcd]] - hRPTP-γ domain 1 + VO4<BR />
	**[[3qce]], [[3qcf]], [[3qcg]], [[3qch]], [[3qci]], [[3qcj]], [[3qck]] - hRPTP-γ domain 1 + inhibitor<br />		**[[3qce]], [[3qcf]], [[3qcg]], [[3qch]], [[3qci]], [[3qcj]], [[3qck]] - hRPTP-γ domain 1 + inhibitor<br />
	**[[3qcl]], [[3qcm]] - hRPTP-γ domain 1 (mutant) + inhibitor<br />		**[[3qcl]], [[3qcm]] - hRPTP-γ domain 1 (mutant) + inhibitor<br />
Line 226:		Line 225:
	**[[3kld]] - mRPTP-γ CA-like domain + contactin 4<br />		**[[3kld]] - mRPTP-γ CA-like domain + contactin 4<br />
	**[[4rca]], [[4y61]] - hRPTP-δ + SLITRK1<br />		**[[4rca]], [[4y61]] - hRPTP-δ + SLITRK1<br />
-	**[[5y32]], [[4yfd]], [[4yh7]] - hRPTP-δ + IL1RAPL1<br />	+	**[[5y32]], [[4yfd]], [[4yh7]], [[5wy8]] - hRPTP-δ + IL1RAPL1<br />
	**[[2yd8]] - hRPTP-σ Ig1-2 domain + sucrose octasulfate<br />		**[[2yd8]] - hRPTP-σ Ig1-2 domain + sucrose octasulfate<br />
	**[[3s97]] - hRPTP-ζ CA-like domain + congtactin Ig domains<br />		**[[3s97]] - hRPTP-ζ CA-like domain + congtactin Ig domains<br />
	**[[1ygr]] – hRPTP CD45 cytoplasmic domain (mutant) + T-cell receptor peptide<br />		**[[1ygr]] – hRPTP CD45 cytoplasmic domain (mutant) + T-cell receptor peptide<br />

-	*'''Dual-specificity tyrosine phosphatase'''	+	*'''Dual-specificity tyrosine phosphatase or Dual-specificity protein phosphatase''' See [[MAP kinase phosphatase]].
-		+
-	**[[~~1t3k~~]] ~~– DUSP (mutant) – ''Arabidopsis thaliana''<br />~~	+
-	**[[6apx]] – hDUSP-1/MBP + monobody<br />	+
-	**[[2g6z]] – hDUSP-5<br />	+
-	**[[4y2e]] – hDUSP-7 (mutant)<br />	+
-	**[[3lj8]] – hDUSP-9<br />	+
-	**[[4jnb]], [[4ki9]] – hDUSP-12 catalytic domain (mutant)<br />	+
-	**[[2wgp]] – hDUSP-14 residues 2-191<br />	+
-	**[[4yr8]] – hDUSP-16 + MAPK8<br />	+
-	**[[4d3p]], [[4d3q]], [[4d3r]] – hDUSP-19 (mutant)<br />	+
-	**[[4woh]] – hDUSP-22 (mutant) + nitrophenolphosphate<br />	+
-	**[[5gtj]] – hDUSP-26<br />	+

	*'''Class II'''		*'''Class II'''
Line 252:		Line 239:
	**[[2cwd]] – LMW-PTP – ''Thermus thermophilus''<br />		**[[2cwd]] – LMW-PTP – ''Thermus thermophilus''<br />
	**[[5got]] – LMW-PTP – ''Streptococcus pyogenes''<br />		**[[5got]] – LMW-PTP – ''Streptococcus pyogenes''<br />
		+	**[[5z3m]] – LMW-PTP – ''Vibrio cholerae''<br />
	**[[1phr]] - bLMW-PTP<br />		**[[1phr]] - bLMW-PTP<br />
-	**[[1xww]], [[4z99]] - hLMW-PTP <br />	+	**[[1xww]], [[4z99]], [[5pnt]] - hLMW-PTP <br />
	**[[1u2p]], [[2luo]] – MtLMW-PTP – ''Mycobacterium tuberculosis''<br />		**[[1u2p]], [[2luo]] – MtLMW-PTP – ''Mycobacterium tuberculosis''<br />
	**[[2oz5]] – MtLMW-PTP + inhibitor<br />		**[[2oz5]] – MtLMW-PTP + inhibitor<br />

Michal Harel at 20:42, 1 October 2018

Michal Harel — Mon, 01 Oct 2018 20:42:46 GMT

←Older revision		Revision as of 20:42, 1 October 2018
Line 15:		Line 15:
	*'''Non-receptor type tyrosine phosphatase'''		*'''Non-receptor type tyrosine phosphatase'''

-	**[[1a5y]], [[2hnp]], [[2hnq]], [[1oem]], [[1oeo]], [[1oes]], [[1oet]], [[1oeu]], [[1oev]], [[1sug]], [[2cm2]], [[2cm3]], [[3eu0]], [[3i80]], [[3a5j]], [[1bzc]] - hPTP-b catalytic domain – human<br />	+	**[[5k9v]] – hPTPN1 - human<br />
-	**[[1gfy]], [[1i57]], [[1pa1]], [[2f6f]], [[3a5k]], [[3zv2]], [[3qkp]], [[3qkq]] - hPTP-b catalytic domain (mutant) <br />	+
-	**[[1wch]] – hPTP-e<br />	+
-	**[[3pdz]] - hPTP-e PDZ2 domain – NMR<BR />	+
-	**[[1gm1]] - mPTP-BL PDZ2 domain – mouse – NMR<BR />	+
-	**[[1ozi]] - mPTP-BL PDZ2 domain (mutant) – NMR<BR />	+
-	**[[3rgo]] – mPTP-1<br />	+
-	**[[2yz1]] – mPTP SHPS-1 catalytic domain<br />	+
-	**[[5k9v]] – hPTPN1<br />	+
	**[[4qah]], [[4qap]], [[4qbe]], [[4qbw]], [[5kaa]], [[5ka8]], [[5ka4]], [[5ka2]], [[5ka1]], [[5ka0]] – hPTPN1 (mutant)<br />		**[[4qah]], [[4qap]], [[4qbe]], [[4qbw]], [[5kaa]], [[5ka8]], [[5ka4]], [[5ka2]], [[5ka1]], [[5ka0]] – hPTPN1 (mutant)<br />
-	**[[6b8e]], [[6b8t]], [[6b8x]], [[6b90]] ~~– hPTPN1B~~ catalytic domain<br />	+	**[[1a5y]], [[2hnp]], [[2hnq]], [[1oem]], [[1oeo]], [[1oes]], [[1oet]], [[1oeu]], [[1oev]], [[1sug]], [[2cm2]], [[2cm3]], [[3eu0]], [[3i80]], [[3a5j]], [[1bzc]], [[6b8e]], [[6b8t]], [[6b8x]], [[6b90]] - hPTP1B catalytic domain <br />
-	**[[6bai]] ~~– hPTPN1B~~ catalytic domain (mutant)<br />	+	**[[1gfy]], [[1i57]], [[1pa1]], [[2f6f]], [[3a5k]], [[3zv2]], [[3qkp]], [[3qkq]], [[6bai]] - hPTP1B catalytic domain (mutant) <br />
	**[[2b49]] – hPTPN3 catalytic domain<br />		**[[2b49]] – hPTPN3 catalytic domain<br />
	**[[4qun]] – hPTPN3 catalytic domain (mutant) <br />		**[[4qun]] – hPTPN3 catalytic domain (mutant) <br />
Line 49:		Line 41:
	**[[5glj]] - hPTPN13 PDZ1 domain <br />		**[[5glj]] - hPTPN13 PDZ1 domain <br />
	**[[3lnx]] – hPTPN13 PDZ2 domain<br />		**[[3lnx]] – hPTPN13 PDZ2 domain<br />
		+	**[[3pdz]] - hPTPN13 PDZ2 domain – NMR<BR />
	**[[2m0z]] - hPTPN13 PDZ2 domain (mutant) – NMR<br />		**[[2m0z]] - hPTPN13 PDZ2 domain (mutant) – NMR<br />
	**[[2bzl]] – hPTPN14 catalytic domain<br />		**[[2bzl]] – hPTPN14 catalytic domain<br />
Line 58:		Line 51:
	**[[1r6h]], [[1v3a]], [[2mbc]] – hPTP PRL-3 – NMR<BR />		**[[1r6h]], [[1v3a]], [[2mbc]] – hPTP PRL-3 – NMR<BR />
	**[[1rxd]] - hPTP IVA-1<br />		**[[1rxd]] - hPTP IVA-1<br />
		+	**[[1gm1]] - mPTP-BL PDZ2 domain – mouse – NMR<BR />
		+	**[[1ozi]] - mPTP-BL PDZ2 domain (mutant) – NMR<BR />
		+	**[[3rgo]] – mPTP-1<br />
		+	**[[2yz1]] – mPTP SHPS-1 catalytic domain<br />
	**[[1zck]], [[1x24]] – rPTP 4A1 – rat<br />		**[[1zck]], [[1x24]] – rPTP 4A1 – rat<br />
	**[[3i36]] – rPTP-η catalytic domain<br />		**[[3i36]] – rPTP-η catalytic domain<br />

Michal Harel at 20:29, 1 October 2018

Michal Harel — Mon, 01 Oct 2018 20:29:27 GMT

←Older revision		Revision as of 20:29, 1 October 2018
Line 23:		Line 23:
	**[[3rgo]] – mPTP-1<br />		**[[3rgo]] – mPTP-1<br />
	**[[2yz1]] – mPTP SHPS-1 catalytic domain<br />		**[[2yz1]] – mPTP SHPS-1 catalytic domain<br />
-	**[[1gwz]], [[2b3o]] – hPTP SHP-1 catalytic domain<br />
-	**[[1x6c]] - hPTP SHP-1 SH2 domain – NMR<BR />
-	**[[2shp]] - hPTP SHP-2 (mutant)<br />
	**[[5k9v]] – hPTPN1<br />		**[[5k9v]] – hPTPN1<br />
	**[[4qah]], [[4qap]], [[4qbe]], [[4qbw]], [[5kaa]], [[5ka8]], [[5ka4]], [[5ka2]], [[5ka1]], [[5ka0]] – hPTPN1 (mutant)<br />		**[[4qah]], [[4qap]], [[4qbe]], [[4qbw]], [[5kaa]], [[5ka8]], [[5ka4]], [[5ka2]], [[5ka1]], [[5ka0]] – hPTPN1 (mutant)<br />
		+	**[[6b8e]], [[6b8t]], [[6b8x]], [[6b90]] – hPTPN1B catalytic domain<br />
		+	**[[6bai]] – hPTPN1B catalytic domain (mutant)<br />
	**[[2b49]] – hPTPN3 catalytic domain<br />		**[[2b49]] – hPTPN3 catalytic domain<br />
	**[[4qun]] – hPTPN3 catalytic domain (mutant) <br />		**[[4qun]] – hPTPN3 catalytic domain (mutant) <br />
Line 35:		Line 34:
	**[[2bij]] – hPTPN5 catalytic domain<br />		**[[2bij]] – hPTPN5 catalytic domain<br />
	**[[2bv5]] - hPTPN5 catalytic domain (mutant) <br />		**[[2bv5]] - hPTPN5 catalytic domain (mutant) <br />
-	**[[~~3ps5~~]] ~~– hPTPN6 (mutant) <br />~~	+	**[[4hjp]], [[1gwz]], [[2b3o]] – hPTPN6 catalytic domain <br />
-	**[[~~4hjp~~]] – hPTPN6 catalytic domain <br />	+	**[[4gry]], [[4grz]], [[4hjq]], [[3ps5]] – hPTPN6 catalytic domain (mutant)<br />
-	**[[4gry]], [[4grz]], [[4hjq]] – hPTPN6 catalytic domain (mutant)<br />	+
	**[[2dn7]] - hPTPN6 FN3 #6 domain - NMR<br />		**[[2dn7]] - hPTPN6 FN3 #6 domain - NMR<br />
	**[[2dju]], [[2edy]] - hPTPN6 FN3 domain - NMR<br />		**[[2dju]], [[2edy]] - hPTPN6 FN3 domain - NMR<br />
		+	**[[1x6c]] - hPTP hPTPN6 SH2 domain – NMR<BR />
	**[[2a3k]], [[1zc0]] – hPTPN7 catalytic domain<br />		**[[2a3k]], [[1zc0]] – hPTPN7 catalytic domain<br />
	**[[2gp0]], [[2hvl]], [[2qdc]], [[2qdm]], [[2qdp]], [[2qds]], [[2qdt]], [[2qdu]], [[3o4s]], [[3o4t]], [[3o4u]] – hPTPN7 catalytic domain (mutant) <br />		**[[2gp0]], [[2hvl]], [[2qdc]], [[2qdm]], [[2qdp]], [[2qds]], [[2qdt]], [[2qdu]], [[3o4s]], [[3o4t]], [[3o4u]] – hPTPN7 catalytic domain (mutant) <br />
Line 46:		Line 45:
	**[[4dgp]] - hPTPN11 SH2+catalytic domains<br />		**[[4dgp]] - hPTPN11 SH2+catalytic domains<br />
	**[[4dgx]], [[4gwf]], [[4h1o]], [[4h34]], [[4nwf]], [[4nwg]], [[4ohd]], [[4ohe]], [[4ohh]], [[4ohi]], [[4ohl]] - hPTPN11 SH2+catalytic domains (mutant)<br />		**[[4dgx]], [[4gwf]], [[4h1o]], [[4h34]], [[4nwf]], [[4nwg]], [[4ohd]], [[4ohe]], [[4ohh]], [[4ohi]], [[4ohl]] - hPTPN11 SH2+catalytic domains (mutant)<br />
-	**[[5j8r]], [[5i6v]], [[5ibm]], [[5ibs]] - hPTPN11 catalytic domain (mutant)<br />	+	**[[5j8r]], [[5i6v]], [[5ibm]], [[5ibs]], [[6atd]], [[2shp]] - hPTPN11 catalytic domain (mutant)<br />
	**[[5hde]] - hPTPN12 catalytic domain <br />		**[[5hde]] - hPTPN12 catalytic domain <br />
	**[[5glj]] - hPTPN13 PDZ1 domain <br />		**[[5glj]] - hPTPN13 PDZ1 domain <br />
Line 62:		Line 61:
	**[[3i36]] – rPTP-η catalytic domain<br />		**[[3i36]] – rPTP-η catalytic domain<br />
	**[[1c0e]] – bPTP (mutant) – bovine<br />		**[[1c0e]] – bPTP (mutant) – bovine<br />
-	**[[1d1p]], [[2j16]] – yPTP - yeast<br />	+	**[[1d1p]], [[2j16]], [[6byf]] – yPTP - yeast<br />
	**[[2j17]] - yPTP (mutant)<br />		**[[2j17]] - yPTP (mutant)<br />
	**[[5xw4]] – yPTPN CDC14 <br />		**[[5xw4]] – yPTPN CDC14 <br />
Line 71:		Line 70:
	**[[3js5]], [[3jvi]] – EhPTP – ''Entamoeba histolytica''<br />		**[[3js5]], [[3jvi]] – EhPTP – ''Entamoeba histolytica''<br />
	**[[2wjd]], [[2wje]], [[2wjf]] – PTP – ''Streptococcus pneumonia''<br />		**[[2wjd]], [[2wje]], [[2wjf]] – PTP – ''Streptococcus pneumonia''<br />
		+	**[[5z59]], [[5z5a]] – TkPTP – ''Thermococcus kodakarensis'' <br />
		+	**[[5z5b]] - TkPTP (mutant)<br />
	**[[3qy6]], [[3qy7]], [[3qy8]] – BsPTP – ''Bacillus subtilis''		**[[3qy6]], [[3qy7]], [[3qy8]] – BsPTP – ''Bacillus subtilis''

	*Non-receptor type PTP complex with peptide		*Non-receptor type PTP complex with peptide

-	**[[1ptt]], [[1ptu]], [[1g1f]], [[1g1g]], [[1g1h]], [[1een]], [[1eeo ]] - hPTP-b catalytic domain (mutant) + peptide<br />
-	**[[3i7z]] - hPTP-b catalytic domain + peptide<br />
	**[[3zmp]], [[3zmq]], [[4zrt]] – hPTPN1 catalytic domain + peptide<br />		**[[3zmp]], [[3zmq]], [[4zrt]] – hPTPN1 catalytic domain + peptide<br />
		+	**[[3i7z]] - hPTP1B catalytic domain + peptide<br />
		+	**[[1ptt]], [[1ptu]], [[1g1f]], [[1g1g]], [[1g1h]], [[1een]], [[1eeo ]] - hPTP1B catalytic domain (mutant) + peptide<br />
		+	**[[1bzh]] - hPTP1B catalytic domain + fluoromalonyl tyrosine peptide<br />
		+	**[[1bzj]] - hPTP1B catalytic domain + phosphotyrosine mimetic<br />
	**[[4qum]], [[4rh5]], [[4rh9]], [[4rhg]], [[4s0g]] – hPTPN3 catalytic domain (mutant) + peptide<br />		**[[4qum]], [[4rh5]], [[4rh9]], [[4rhg]], [[4s0g]] – hPTPN3 catalytic domain (mutant) + peptide<br />
-	**[[1bzh]] - hPTP 1B catalytic domain + fluoromalonyl tyrosine peptide<br />
-	**[[1bzj]] - hPTP 1B catalytic domain + phosphotyrosine mimetic<br />
	**[[3nfk]], [[3nfl]], [[5eyz]], [[5ez0]] - hPTPN4 PDZ domain + peptide<br />		**[[3nfk]], [[3nfl]], [[5eyz]], [[5ez0]] - hPTPN4 PDZ domain + peptide<br />
	**[[2yu7]], [[2rmx]] – hPTPN6 SH2 domain + peptide – NMR<BR />		**[[2yu7]], [[2rmx]] – hPTPN6 SH2 domain + peptide – NMR<BR />
Line 104:		Line 105:
	*Non-receptor type PTP complex with small molecule		*Non-receptor type PTP complex with small molecule

-	**[[1ptv]], [[1pty]] - ~~hPTP-b~~ catalytic domain (mutant) + phosphotyrosine<br />	+	**[[1ptv]], [[1pty]] - hPTP1B catalytic domain (mutant) + phosphotyrosine<br />
-	**[[1aax]] - ~~hPTP-b~~ catalytic domain (mutant) + bis-phosphophenyl methane<br />	+	**[[1aax]] - hPTP1B catalytic domain (mutant) + bis-phosphophenyl methane<br />
-	**[[1ecv]], [[1c83]], [[1c84]], [[1c85]], [[1c86]], [[1c87]], [[1c88]], [[1g7f]], [[1g7g]], [[1jf7]], [[1l8g]], [[1kak]], [[1kav]], [[1lqf]], [[1nl9]], [[1nny]], [[1no6]], [[1nz7]], [[1ony]], [[1onz]], [[1ph0]], [[1pxh]], [[1pyn]], [[1q1m]], [[1q6j]], [[1q6m]], [[1q6n]], [[1q6p]], [[1q6s]], [[1q6t]], [[1qxk]], [[1t48]], [[1t49]], [[1t4j]], [[1xbo]], [[1wax]], [[2bgd]], [[2bge]], [[2azr]], [[2b07]], [[2f6t]], [[2f6v]], [[2f6w]], [[2f6y]], [[2f6z]], [[2f70]], [[2f71]], [[2fjn]], [[2cm7]], [[2cm8]], [[2cma]], [[2cmb]], [[2cmc]], [[2h4g]], [[2h4k]], [[2hb1]], [[2cne]], [[2cnf]], [[2cng]], [[2cnh]], [[2cni]], [[2nt7]], [[2nta]], [[2veu]], [[2vev]], [[2vew]], [[2vex]], [[2vey]], [[2qbp]], [[2qbq]], [[2qbr]], [[2qbs]], [[3cwe]], [[3d9c]], [[2zmm]], [[2zn7]], [[3eax]], [[3eb1]], [[3sme]], [[4i8n]], [[4y14]] - ~~hPTP-b~~ catalytic domain + inhibitor<br />	+	**[[1ecv]], [[1c83]], [[1c84]], [[1c85]], [[1c86]], [[1c87]], [[1c88]], [[1g7f]], [[1g7g]], [[1jf7]], [[1l8g]], [[1kak]], [[1kav]], [[1lqf]], [[1nl9]], [[1nny]], [[1no6]], [[1nz7]], [[1ony]], [[1onz]], [[1ph0]], [[1pxh]], [[1pyn]], [[1q1m]], [[1q6j]], [[1q6m]], [[1q6n]], [[1q6p]], [[1q6s]], [[1q6t]], [[1qxk]], [[1t48]], [[1t49]], [[1t4j]], [[1xbo]], [[1wax]], [[2bgd]], [[2bge]], [[2azr]], [[2b07]], [[2f6t]], [[2f6v]], [[2f6w]], [[2f6y]], [[2f6z]], [[2f70]], [[2f71]], [[2fjn]], [[2cm7]], [[2cm8]], [[2cma]], [[2cmb]], [[2cmc]], [[2h4g]], [[2h4k]], [[2hb1]], [[2cne]], [[2cnf]], [[2cng]], [[2cnh]], [[2cni]], [[2nt7]], [[2nta]], [[2veu]], [[2vev]], [[2vew]], [[2vex]], [[2vey]], [[2qbp]], [[2qbq]], [[2qbr]], [[2qbs]], [[3cwe]], [[3d9c]], [[2zmm]], [[2zn7]], [[3eax]], [[3eb1]], [[3sme]], [[4i8n]], [[4y14]], [[6bmr]], [[6bmv]], [[6bmx]], [[6bmu]], [[6bmw]], [[6bmy]], [[5t19]], [[5k9w]], [[6b8z]] - hPTP1B catalytic domain + inhibitor<br />
-	**[[1nwl]], [[1nwe]], [[2fjm]] ~~- hPTP-b catalytic domain~~ (mutant) + inhibitor<br />	+	**[[5kad]], [[5kac]], [[5kab]], [[5ka9]], [[5ka7]], [[5ka3]], [[6b95]], [[1nwl]], [[1nwe]], [[2fjm]], [[6bn5]] – hPTPN1B (mutant) + inhibitor<br />
	**[[4bjo]] – hPTP1 catalytic domain + NO3<br />		**[[4bjo]] – hPTP1 catalytic domain + NO3<br />
-	**[[5t19]], [[5k9w]] – hPTPN1b + inhibitor<br />
-	**[[5kad]], [[5kac]], [[5kab]], [[5ka9]], [[5ka7]], [[5ka3]] – hPTPN1b (mutant) + inhibitor<br />
	**[[4ri4]], [[4ri5]] – hPTPN3 catalytic domain (mutant) + VO4<br />		**[[4ri4]], [[4ri5]] – hPTPN3 catalytic domain (mutant) + VO4<br />
-	**[[~~3rgq~~]] – ~~mPTP-1~~ + ~~Pi(5)P~~<br />	+	**[[6h8r]] – hPTPN5 + inhibitor<br />
	**[[2cjz]] - hPTPN5 catalytic domain (mutant) + phosphotyrosine<br />		**[[2cjz]] - hPTPN5 catalytic domain (mutant) + phosphotyrosine<br />
	**[[4ge2]], [[4ge5]], [[4ge6]] – hPTP9 catalytic domain + inhibitor<br />		**[[4ge2]], [[4ge5]], [[4ge6]] – hPTP9 catalytic domain + inhibitor<br />
Line 129:		Line 128:
	**[[2i6m]] – SsPTP + WO4<BR />		**[[2i6m]] – SsPTP + WO4<BR />
	**[[3ido]] – EhPTP + HEPES<br />		**[[3ido]] – EhPTP + HEPES<br />
		+	**[[3rgq]] – mPTP-1 + Pi(5)P<br />
		+	**[[6h8s]] – mPTPN5 + inhibitor<br />

	*Non-receptor type PTP complex with protein		*Non-receptor type PTP complex with protein

-	**[[2b4s]] - ~~hPTP-b~~ catalytic domain + insulin receptor<br />	+	**[[2b4s]] - hPTP1B catalytic domain + insulin receptor<br />
	**[[2gph]] - hPTPN7 catalytic domain (mutant) + MAPK2<br />		**[[2gph]] - hPTPN7 catalytic domain (mutant) + MAPK2<br />
	**[[1g4u]] – StPTP + RAS-related C3 botulinum toxin substrate <br />		**[[1g4u]] – StPTP + RAS-related C3 botulinum toxin substrate <br />

Joel L. Sussman at 19:02, 28 December 2017

Joel L. Sussman — Thu, 28 Dec 2017 19:02:02 GMT

←Older revision		Revision as of 19:02, 28 December 2017
Line 228:		Line 228:
	**[[3kld]] - mRPTP-γ CA-like domain + contactin 4<br />		**[[3kld]] - mRPTP-γ CA-like domain + contactin 4<br />
	**[[4rca]], [[4y61]] - hRPTP-δ + SLITRK1<br />		**[[4rca]], [[4y61]] - hRPTP-δ + SLITRK1<br />
-	**[[~~4yfc~~]], [[4yfd]], [[4yh7]] - hRPTP-δ + IL1RAPL1<br />	+	**[[5y32]], [[4yfd]], [[4yh7]] - hRPTP-δ + IL1RAPL1<br />
	**[[2yd8]] - hRPTP-σ Ig1-2 domain + sucrose octasulfate<br />		**[[2yd8]] - hRPTP-σ Ig1-2 domain + sucrose octasulfate<br />
	**[[3s97]] - hRPTP-ζ CA-like domain + congtactin Ig domains<br />		**[[3s97]] - hRPTP-ζ CA-like domain + congtactin Ig domains<br />

Michal Harel at 11:44, 14 November 2017

Michal Harel — Tue, 14 Nov 2017 11:44:25 GMT

←Older revision		Revision as of 11:44, 14 November 2017
Line 26:		Line 26:
	**[[1x6c]] - hPTP SHP-1 SH2 domain – NMR<BR />		**[[1x6c]] - hPTP SHP-1 SH2 domain – NMR<BR />
	**[[2shp]] - hPTP SHP-2 (mutant)<br />		**[[2shp]] - hPTP SHP-2 (mutant)<br />
-	**[[4qah]], [[4qap]], [[4qbe]], [[4qbw]] – hPTPN1 (mutant)<br />	+	**[[5k9v]] – hPTPN1<br />
		+	**[[4qah]], [[4qap]], [[4qbe]], [[4qbw]], [[5kaa]], [[5ka8]], [[5ka4]], [[5ka2]], [[5ka1]], [[5ka0]] – hPTPN1 (mutant)<br />
	**[[2b49]] – hPTPN3 catalytic domain<br />		**[[2b49]] – hPTPN3 catalytic domain<br />
	**[[4qun]] – hPTPN3 catalytic domain (mutant) <br />		**[[4qun]] – hPTPN3 catalytic domain (mutant) <br />
Line 44:		Line 45:
	**[[3b7o]], [[3zm0]], [[3zm1]], [[3zm2]], [[3zm3]] - hPTPN11 catalytic domain<br />		**[[3b7o]], [[3zm0]], [[3zm1]], [[3zm2]], [[3zm3]] - hPTPN11 catalytic domain<br />
	**[[4dgp]] - hPTPN11 SH2+catalytic domains<br />		**[[4dgp]] - hPTPN11 SH2+catalytic domains<br />
-	**[[4dgx]], [[4gwf]], [[4h1o]], [[4h34]], [[4nwf]], [[4nwg]], [[4ohd]], [[4ohe]], [[4ohh]], [[4ohi]] - hPTPN11 SH2+catalytic domains (mutant)<br />	+	**[[4dgx]], [[4gwf]], [[4h1o]], [[4h34]], [[4nwf]], [[4nwg]], [[4ohd]], [[4ohe]], [[4ohh]], [[4ohi]], [[4ohl]] - hPTPN11 SH2+catalytic domains (mutant)<br />
	**[[5j8r]], [[5i6v]], [[5ibm]], [[5ibs]] - hPTPN11 catalytic domain (mutant)<br />		**[[5j8r]], [[5i6v]], [[5ibm]], [[5ibs]] - hPTPN11 catalytic domain (mutant)<br />
		+	**[[5hde]] - hPTPN12 catalytic domain <br />
	**[[5glj]] - hPTPN13 PDZ1 domain <br />		**[[5glj]] - hPTPN13 PDZ1 domain <br />
	**[[3lnx]] – hPTPN13 PDZ2 domain<br />		**[[3lnx]] – hPTPN13 PDZ2 domain<br />
Line 52:		Line 54:
	**[[2oc3]] – hPTPN18<br />		**[[2oc3]] – hPTPN18<br />
	**[[2p6x]], [[2qcj]], [[3h2x]] – hPTPN22 catalytic domain<br />		**[[2p6x]], [[2qcj]], [[3h2x]] – hPTPN22 catalytic domain<br />
-	**[[3rau]] ~~- hPTPN23 His~~ domain<br />	+	**[[5cru]], [[5mjz]], [[3rau]] – hRPTP23 domain Bro residues 1-361<br />
-	**[[~~5cru~~]] – hRPTP23 ~~domain Bro~~<br />	+	**[[5lm2]] – hRPTP23 residues 362-713<br />
-	**[[1xm2]] – hPTP PRL-1<br />	+	**[[1xm2]], [[1rxd]] – hPTP PRL-1<br />
-	**[[1r6h]], [[1v3a]], [[2mbc]] – hPTP ~~IVA~~-3 – NMR<BR />	+	**[[1r6h]], [[1v3a]], [[2mbc]] – hPTP PRL-3 – NMR<BR />
	**[[1rxd]] - hPTP IVA-1<br />		**[[1rxd]] - hPTP IVA-1<br />
	**[[1zck]], [[1x24]] – rPTP 4A1 – rat<br />		**[[1zck]], [[1x24]] – rPTP 4A1 – rat<br />
Line 62:		Line 64:
	**[[1d1p]], [[2j16]] – yPTP - yeast<br />		**[[1d1p]], [[2j16]] – yPTP - yeast<br />
	**[[2j17]] - yPTP (mutant)<br />		**[[2j17]] - yPTP (mutant)<br />
		+	**[[5xw4]] – yPTPN CDC14 <br />
	**[[1g4w]] – StPTP – ''Salmonella typhimurium''<br />		**[[1g4w]] – StPTP – ''Salmonella typhimurium''<br />
	**[[2i6i]], [[3ro1]] – SsPTP – ''Sulfolobus solfataricus''<br />		**[[2i6i]], [[3ro1]] – SsPTP – ''Sulfolobus solfataricus''<br />
Line 83:		Line 86:
	**[[3d42]], [[3d44]] – hPTPN7 catalytic domain (mutant) + peptide<br />		**[[3d42]], [[3d44]] – hPTPN7 catalytic domain (mutant) + peptide<br />
	**[[4icz]] – hPTPN9 catalytic domain + peptide<br />		**[[4icz]] – hPTPN9 catalytic domain + peptide<br />
-	**[[3tl0]], [[3tkz]],[[5df6]], [[4qsy]] – hPTPN11 SH2 domain + peptide<br />	+	**[[3tl0]], [[3tkz]],[[5df6]], [[4qsy]],[[5x94]], [[5x7b]] – hPTPN11 SH2 domain + peptide<br />
		+	**[[5o2p]] – hPTPN12 SH3 domain/peptide<br />
	**[[3lny]] - hPTPN13 PDZ2 domain + peptide<br />		**[[3lny]] - hPTPN13 PDZ2 domain + peptide<br />
	**[[4gfu]], [[4gfv]] - hPTPN18 residues 6-300 + peptide<br />		**[[4gfu]], [[4gfv]] - hPTPN18 residues 6-300 + peptide<br />
Line 89:		Line 93:
	**[[3brh]], [[3olr]] - hPTPN22 catalytic domain + peptide<br />		**[[3brh]], [[3olr]] - hPTPN22 catalytic domain + peptide<br />
	**[[3omh]] - hPTPN22 catalytic domain (mutant) + peptide<br />		**[[3omh]] - hPTPN22 catalytic domain (mutant) + peptide<br />
-	**[[5crv]] – hRPTP23 domain Bro + STAM2 peptide<br />	+	**[[5crv]], [[5mk3]], [[5mk2]], [[5mk1]], [[5mk0]], [[5mjy]] – hRPTP23 domain Bro + STAM2 peptide<br />
		+	**[[5lm2]] – hRPTP23 residues 362-713 + UBAP-1 peptide<br />
	**[[3rz2]] - rPTP 4A1 + peptide<br />		**[[3rz2]] - rPTP 4A1 + peptide<br />
	**[[1fpr]] - hPTP SHP-1 catalytic domain + peptide<br />		**[[1fpr]] - hPTP SHP-1 catalytic domain + peptide<br />
Line 95:		Line 100:
	**[[1vj6]] – mPTP PDZ2 domain + APC C terminal – NMR<br />		**[[1vj6]] – mPTP PDZ2 domain + APC C terminal – NMR<br />
	**[[2dxp]], [[2i6o]] – SsPTP (mutant) + peptide<br />		**[[2dxp]], [[2i6o]] – SsPTP (mutant) + peptide<br />
		+	**[[5xw5]] – yPTPN CDC14 + SWI6 peptide<br />

	*Non-receptor type PTP complex with small molecule		*Non-receptor type PTP complex with small molecule
Line 103:		Line 109:
	**[[1nwl]], [[1nwe]], [[2fjm]] - hPTP-b catalytic domain (mutant) + inhibitor<br />		**[[1nwl]], [[1nwe]], [[2fjm]] - hPTP-b catalytic domain (mutant) + inhibitor<br />
	**[[4bjo]] – hPTP1 catalytic domain + NO3<br />		**[[4bjo]] – hPTP1 catalytic domain + NO3<br />
		+	**[[5t19]], [[5k9w]] – hPTPN1b + inhibitor<br />
		+	**[[5kad]], [[5kac]], [[5kab]], [[5ka9]], [[5ka7]], [[5ka3]] – hPTPN1b (mutant) + inhibitor<br />
	**[[4ri4]], [[4ri5]] – hPTPN3 catalytic domain (mutant) + VO4<br />		**[[4ri4]], [[4ri5]] – hPTPN3 catalytic domain (mutant) + VO4<br />
	**[[3rgq]] – mPTP-1 + Pi(5)P<br />		**[[3rgq]] – mPTP-1 + Pi(5)P<br />
Line 111:		Line 119:
	**[[2m10]] - hPTPN13 PDZ2 domain (mutant) + azobenzene derivative – NMR<br />		**[[2m10]] - hPTPN13 PDZ2 domain (mutant) + azobenzene derivative – NMR<br />
	**[[2qct]], [[4j51]] – hPTPN22 catalytic domain + inhibitor<br />		**[[2qct]], [[4j51]] – hPTPN22 catalytic domain + inhibitor<br />
		+	**[[5h08]] – hPTP ζ D1 domain + inhibitor<br />
		+	**[[5bx1]] – hPTP PRL-1 + inhibitor<br />
	**[[1zcl]] - rPTP 4A1 (mutant) + sulfate<br />		**[[1zcl]] - rPTP 4A1 (mutant) + sulfate<br />
	**[[1dg9]] – bPTP + HEPES<br />		**[[1dg9]] – bPTP + HEPES<br />
Line 127:		Line 137:
	**[[1jyo]] – StPTP + secretion chaperone SICP<br />		**[[1jyo]] – StPTP + secretion chaperone SICP<br />
	**[[4je4]], [[4jeg]] – hPTPN11 catalytic domain + monobody<br />		**[[4je4]], [[4jeg]] – hPTPN11 catalytic domain + monobody<br />
		+	**[[5lxq]] – mPTP + CNNM2<br />
		+	**[[5k25]], [[5k24]], [[5k23]] – hPTP PRL-2 + CNNM3<br />
		+	**[[5k22]] – hPTP PRL-2 (mutant) + CNNM3<br />
		+	**[[5tsr]] – hPTP PRL-3 (mutant) + CNNM3<br />
		+	**[[5mmz]] – mPTP 4A1 + CNNM2<br />
	**[[4zj7]] – yPTPN CDC14 C terminal + importin<br />		**[[4zj7]] – yPTPN CDC14 C terminal + importin<br />

Line 221:		Line 236:

	**[[1t3k]] – DUSP (mutant) – ''Arabidopsis thaliana''<br />		**[[1t3k]] – DUSP (mutant) – ''Arabidopsis thaliana''<br />
		+	**[[6apx]] – hDUSP-1/MBP + monobody<br />
	**[[2g6z]] – hDUSP-5<br />		**[[2g6z]] – hDUSP-5<br />
	**[[4y2e]] – hDUSP-7 (mutant)<br />		**[[4y2e]] – hDUSP-7 (mutant)<br />
Line 253:		Line 269:
	**[[1z12]] - bLMW-PTP + VO4<br />		**[[1z12]] - bLMW-PTP + VO4<br />
	**[[1z13]] - bPTP + MoO4<br />		**[[1z13]] - bPTP + MoO4<br />
		+	**[[5jnw]] – bLMW-PTP + inhibitor <br />
	**[[3rof]] – LMW-PTP-A + peptide – ''Staphylococcus aureus''<br />		**[[3rof]] – LMW-PTP-A + peptide – ''Staphylococcus aureus''<br />
	**[[1u2q]] – MtLMW-PTP + glycerol<br />		**[[1u2q]] – MtLMW-PTP + glycerol<br />
Line 269:		Line 286:
	**[[1cwt]] - hCDC25B catalytic domain + Methyl-Hg<br />		**[[1cwt]] - hCDC25B catalytic domain + Methyl-Hg<br />
	**[[3op3]] – hCDC25C residues 270-462		**[[3op3]] – hCDC25C residues 270-462
		+
		+	*'''Class IV'''
		+
		+	**[[4tvv]] – PTP – ''Legionella pneumophila''<br />

	*'''T-cell tyrosine phosphatase'''		*'''T-cell tyrosine phosphatase'''
Line 279:		Line 300:
	**[[4r0s]] – PaPTP – ''Pseudomonas aeruginosa''<br />		**[[4r0s]] – PaPTP – ''Pseudomonas aeruginosa''<br />
	**[[4r0t]] – PaPTP (mutant) + tyrosine<br />		**[[4r0t]] – PaPTP (mutant) + tyrosine<br />
		+	**[[5ncr]] – PTP (mutant) – ORF virus<br />

	}}		}}

Michal Harel at 09:31, 29 November 2016

Michal Harel — Tue, 29 Nov 2016 09:31:11 GMT

(Difference between revisions)