User:Karsten Theis/FadA5 thiolase - Revision history

Karsten Theis at 19:21, 25 January 2018

Karsten Theis — Thu, 25 Jan 2018 19:21:23 GMT

←Older revision		Revision as of 19:21, 25 January 2018
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	==Structure of Fad A5==		==Structure of Fad A5==
-	<StructureSection load='~~4ubt~~' size='~~340~~' side='right' caption='Fad A5 thiolase' scene=''>	+	<StructureSection load='' size='600' side='right' caption='Fad A5 thiolase' scene='77/778945/Subdomain/2'>

	FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)		FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)

Karsten Theis — Thu, 25 Jan 2018 19:20:01 GMT

Fighting tuberculosis

←Older revision		Revision as of 19:20, 25 January 2018
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	==Fighting tuberculosis==		==Fighting tuberculosis==
		+	Space for an introduction to tuberculosis resistance
		+
	==Structure of Fad A5==		==Structure of Fad A5==
	<StructureSection load='4ubt' size='340' side='right' caption='Fad A5 thiolase' scene=''>		<StructureSection load='4ubt' size='340' side='right' caption='Fad A5 thiolase' scene=''>

Karsten Theis — Thu, 25 Jan 2018 19:19:08 GMT

←Older revision

Revision as of 19:19, 25 January 2018

Karsten Theis — Thu, 25 Jan 2018 18:43:37 GMT

Structure of Fad A5

←Older revision		Revision as of 18:43, 25 January 2018
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-	<scene name='77/778945/Coaac/2'>acetylated CoA binds to FadA5</scene>	+	<scene name='77/778945/Coaac/5'>acetylated CoA binds to FadA5</scene>

-	Same with <scene name='77/778945/Coaac/3'>labels</scene>	+	Same with <scene name='77/778945/Coaac/4'>labels</scene>

		+	connect 2.5 4.0 (visible and WAT)(visible) HBOND

	blue: 177, 221, 224, 242, 243, 151		blue: 177, 221, 224, 242, 243, 151

Karsten Theis — Thu, 25 Jan 2018 18:15:00 GMT

Structure of Fad A5

←Older revision		Revision as of 18:15, 25 January 2018
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-	<scene name='77/778945/Coaac/1'>acetylated CoA binds to FadA5</scene>	+	<scene name='77/778945/Coaac/2'>acetylated CoA binds to FadA5</scene>
		+
		+	Same with <scene name='77/778945/Coaac/3'>labels</scene>
		+
		+
	blue: 177, 221, 224, 242, 243, 151		blue: 177, 221, 224, 242, 243, 151

Line 20:		Line 24:
	orange: 17, 248, 246, 93		orange: 17, 248, 246, 93

-	all: 377, 315, 317, 343, 173, 177, 221, 224, 242, 243, 151, ~~377~~, ~~315~~, ~~317, 343, 173~~,	+	all: 377, 315, 317, 343, 173, 177, 221, 224, 242, 243, 151, 17, 248, 246, 93

	</StructureSection>		</StructureSection>

Karsten Theis — Thu, 25 Jan 2018 17:58:53 GMT

Structure of Fad A5

←Older revision		Revision as of 17:58, 25 January 2018
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	* [[4ubu]] The inactive C93S variant in complex with CoA		* [[4ubu]] The inactive C93S variant in complex with CoA
	* [[4ubt]] The inactive C93S variant in complex with a cleaved product (CoA and a cholesterol		* [[4ubt]] The inactive C93S variant in complex with a cleaved product (CoA and a cholesterol
		+
		+
		+	<scene name='77/778945/Coaac/1'>acetylated CoA binds to FadA5</scene>
		+	blue: 177, 221, 224, 242, 243, 151
		+
		+	green: 377, 315, 317, 343, 173,
		+
		+	orange: 17, 248, 246, 93
		+
		+	all: 377, 315, 317, 343, 173, 177, 221, 224, 242, 243, 151, 377, 315, 317, 343, 173,

	</StructureSection>		</StructureSection>

Karsten Theis — Tue, 23 Jan 2018 21:00:23 GMT

Structure of Fad A5

←Older revision		Revision as of 21:00, 23 January 2018
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	FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)		FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)
-	and forms a <scene name='77/778945/Dimer/3'>dimer</scene>.	+	and forms a <scene name='77/778945/Dimer/2'>dimer</scene>.

	The following structures have been determined:		The following structures have been determined:

Karsten Theis — Tue, 23 Jan 2018 20:59:05 GMT

Structure of Fad A5

←Older revision		Revision as of 20:59, 23 January 2018
Line 4:		Line 4:

	FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)		FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)
-	and forms a <scene name='77/778945/Dimer/2'>dimer</scene>.	+	and forms a <scene name='77/778945/Dimer/3'>dimer</scene>.

	The following structures have been determined:		The following structures have been determined:

Karsten Theis — Tue, 23 Jan 2018 20:57:06 GMT

Structure of Fad A5

←Older revision		Revision as of 20:57, 23 January 2018
Line 4:		Line 4:

	FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)		FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)
-	and forms a <scene name='77/778945/Dimer/1'>dimer</scene>.	+	and forms a <scene name='77/778945/Dimer/2'>dimer</scene>.

	The following structures have been determined:		The following structures have been determined:
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	</StructureSection>		</StructureSection>
		+
	== References ==		== References ==
	http://dx.doi.org/10.1016/j.str.2014.10.010		http://dx.doi.org/10.1016/j.str.2014.10.010
	<references/>		<references/>

Karsten Theis — Tue, 23 Jan 2018 20:54:13 GMT

←Older revision		Revision as of 20:54, 23 January 2018
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	==Fighting tuberculosis==		==Fighting tuberculosis==
	==Structure of Fad A5==		==Structure of Fad A5==
-	<StructureSection load='~~1ubt~~' size='340' side='right' caption='Fad A5 thiolase' scene=''>	+	<StructureSection load='4ubt' size='340' side='right' caption='Fad A5 thiolase' scene=''>

-	FadA5 thiolase has three subdomains (I: ~~1–125~~,~~246–266~~; II: 126-245; III: ~~267–391~~)	+	FadA5 thiolase has three <scene name='77/778945/Subdomain/2'>subdomains</scene> (I: 1-125,246-266; II: 126-245; III: 267-391)
-	and forms a dimer.	+	and forms a <scene name='77/778945/Dimer/1'>dimer</scene>.

	The following structures have been determined:		The following structures have been determined:
-	[[4ubv]] Acetylated FadA5 in complex with CoA	+	* [[4ubv]] Acetylated FadA5 in complex with CoA
-	[[4ubw]] FadA5 on its own	+	* [[4ubw]] FadA5 on its own
-	[[4ubu]] The inactive C93S variant in complex with CoA	+	* [[4ubu]] The inactive C93S variant in complex with CoA
-	[[4ubt]] The inactive C93S variant in complex with a cleaved product (CoA and a cholesterol	+	* [[4ubt]] The inactive C93S variant in complex with a cleaved product (CoA and a cholesterol

	</StructureSection>		</StructureSection>