User:Kay Owosela - Revision history

Kay Owosela: /* Stoichiometry */

Kay Owosela — Mon, 22 Dec 2008 04:12:14 GMT

Stoichiometry

Kay Owosela: /* Stoichiometry */

Kay Owosela — Mon, 22 Dec 2008 01:40:51 GMT

Stoichiometry

←Older revision		Revision as of 01:40, 22 December 2008
Line 29:		Line 29:
	<b><u>Quarternary Interactions</u></b>		<b><u>Quarternary Interactions</u></b>

-	~~Two hexameric rings~~ are connected through couple of different type of interactions, such as: Hydrogen Bonds, and Non-bonded contacts. Each subunit has area’s that are proportional to the surface area of the corresponding protein chains. Each subunit only interacts with four other protomers in the protein.	+	The subunits are connected through couple of different type of interactions, such as: Hydrogen Bonds, and Non-bonded contacts. Each subunit has area’s that are proportional to the surface area of the corresponding protein chains. Each subunit only interacts with four other protomers in the protein.

	Subunit Connections:		Subunit Connections:

Kay Owosela: /* Stoichiometry */

Kay Owosela — Mon, 22 Dec 2008 01:37:19 GMT

Stoichiometry

←Older revision		Revision as of 01:37, 22 December 2008
Line 29:		Line 29:
	<b><u>Quarternary Interactions</u></b>		<b><u>Quarternary Interactions</u></b>

-	~~Interacting subunits~~ are connected through couple of different type of interactions, such as: Hydrogen Bonds, and Non-bonded contacts. Each subunit has area’s that are proportional to the surface area of the corresponding protein chains. Each subunit only interacts with four other protomers in the protein.	+	Two hexameric rings are connected through couple of different type of interactions, such as: Hydrogen Bonds, and Non-bonded contacts. Each subunit has area’s that are proportional to the surface area of the corresponding protein chains. Each subunit only interacts with four other protomers in the protein.

	Subunit Connections:		Subunit Connections:
-

	<scene name='User:Kay_Owosela/Protomers_with_interactions/1'>Glutamine Synthetase with interactions between all residues</scene>		<scene name='User:Kay_Owosela/Protomers_with_interactions/1'>Glutamine Synthetase with interactions between all residues</scene>

Kay Owosela: /* Stoichiometry */

Kay Owosela — Mon, 22 Dec 2008 00:40:41 GMT

Stoichiometry

←Older revision		Revision as of 00:40, 22 December 2008
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	<scene name='User:Kay_Owosela/Protomers_with_interactions/1'>Glutamine Synthetase with interactions between all residues</scene>		<scene name='User:Kay_Owosela/Protomers_with_interactions/1'>Glutamine Synthetase with interactions between all residues</scene>
		+
		+
	<scene name='User:Kay_Owosela/Interactions_with_chain_a/1'>Interactions with Chain A</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_a/1'>Interactions with Chain A</scene>

Kay Owosela: /* Stoichiometry */

Kay Owosela — Mon, 22 Dec 2008 00:40:19 GMT

Stoichiometry

←Older revision		Revision as of 00:40, 22 December 2008
Line 33:		Line 33:
	Subunit Connections:		Subunit Connections:

		+
		+	<scene name='User:Kay_Owosela/Protomers_with_interactions/1'>Glutamine Synthetase with interactions between all residues</scene>
	<scene name='User:Kay_Owosela/Interactions_with_chain_a/1'>Interactions with Chain A</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_a/1'>Interactions with Chain A</scene>

Kay Owosela: /* Active Site */

Kay Owosela — Mon, 22 Dec 2008 00:21:47 GMT

Active Site

←Older revision		Revision as of 00:21, 22 December 2008
Line 82:		Line 82:

	= Active Site =		= Active Site =
-	Glutamine Synthetase is dodecameric and has 622 symmetry. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The <scene name='User:Kay_Owosela/Active_site/5'>active site</scene> can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.	+	Glutamine Synthetase is dodecameric and has 622 symmetry. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers and indicated by the yellow manganese atoms highlighted in the applet. The <scene name='User:Kay_Owosela/Active_site/5'>active site</scene> can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.

	= Reference =		= Reference =

Kay Owosela: /* Active Site */

Kay Owosela — Sun, 21 Dec 2008 23:08:33 GMT

Active Site

←Older revision		Revision as of 23:08, 21 December 2008
Line 82:		Line 82:

	= Active Site =		= Active Site =
-	Glutamine Synthetase is dodecameric and has 622 symmetry. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The <scene name='User:Kay_Owosela/Active_site/4'>active site</scene> can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.	+	Glutamine Synthetase is dodecameric and has 622 symmetry. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The <scene name='User:Kay_Owosela/Active_site/5'>active site</scene> can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.

	= Reference =		= Reference =

Kay Owosela: /* Active Site */

Kay Owosela — Sun, 21 Dec 2008 20:34:12 GMT

Active Site

←Older revision		Revision as of 20:34, 21 December 2008
Line 82:		Line 82:

	= Active Site =		= Active Site =
-	Glutamine Synthetase is dodecameric and has 622 symmetry~~, which means it could be split in to twelve equal parts~~. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The <scene name='User:Kay_Owosela/Active_site/4'>active site</scene> can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.	+	Glutamine Synthetase is dodecameric and has 622 symmetry. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The <scene name='User:Kay_Owosela/Active_site/4'>active site</scene> can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.

	= Reference =		= Reference =

Kay Owosela: /* Active Site */

Kay Owosela — Sun, 21 Dec 2008 20:09:31 GMT

Active Site

←Older revision		Revision as of 20:09, 21 December 2008
Line 82:		Line 82:

	= Active Site =		= Active Site =
-	Glutamine Synthetase is dodecameric and has 622 symmetry, which means it could be split in to twelve equal parts. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The active site can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.	+	Glutamine Synthetase is dodecameric and has 622 symmetry, which means it could be split in to twelve equal parts. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The <scene name='User:Kay_Owosela/Active_site/4'>active site</scene> can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.

	= Reference =		= Reference =

Kay Owosela: /* Active Site */

Kay Owosela — Sun, 21 Dec 2008 19:50:49 GMT

Active Site

←Older revision		Revision as of 19:50, 21 December 2008
Line 82:		Line 82:

	= Active Site =		= Active Site =
-	Glutamine Synthetase is dodecameric and has 622 symmetry, which means it could be split in to twelve equal parts. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The active site can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.	+	Glutamine Synthetase is dodecameric and has 622 symmetry, which means it could be split in to twelve equal parts. Each active site is located at an interface between subunits, and is made up of residues from two adjacent subunits. The <scene name='User:Kay_Owosela/Active_site_location/1'>active site location</scene> is between two protomers as highlighted in the applet. The active site can be described as a 'bifunnel' in which ATP and glutamate bind at opposite ends. It is surrounded by three important ligands: ADP, TL as labeled in the applet. ADP is short for Adenosite Diphosphate. And the metal ion, Thallium is also labeled in the applet.

	= Reference =		= Reference =

←Older revision		Revision as of 04:12, 22 December 2008
Line 38:		Line 38:
	<scene name='User:Kay_Owosela/Interactions_with_chain_a/1'>Interactions with Chain A</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_a/1'>Interactions with Chain A</scene>

-	'''A''' ~~is bonded to~~ four subunits, '''F''', '''G''', '''H''', and '''B''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''A''' interacts with four subunits, '''F''', '''G''', '''H''', and '''B'''.

	<scene name='User:Kay_Owosela/Interactions_between_chain_b/1'>Interactions with Chain B</scene>		<scene name='User:Kay_Owosela/Interactions_between_chain_b/1'>Interactions with Chain B</scene>

-	'''B''' ~~is bonded to~~ four subunits, '''H''', '''I''', '''A''', and '''C''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''B''' interacts with four subunits, '''H''', '''I''', '''A''', and '''C'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_c/1'>Interactions with Chain C</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_c/1'>Interactions with Chain C</scene>

-	'''C''' ~~is bonded to~~ four subunits, '''B''', '''D''', '''I''', and '''J''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''C''' interacts with four subunits, '''B''', '''D''', '''I''', and '''J'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_d/1'>Interactions with Chain D</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_d/1'>Interactions with Chain D</scene>

-	'''D''' ~~is bonded to~~ four subunits, '''C''', '''I''', '''J''', and '''K''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''D''' interacts with four subunits, '''C''', '''I''', '''J''', and '''K'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_e/1'>Interactions with Chain E</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_e/1'>Interactions with Chain E</scene>

-	'''E''' ~~is bonded to~~ four subunits, '''L''', '''F''', '''D''', and '''K''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''E''' interacts with four subunits, '''L''', '''F''', '''D''', and '''K'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_f/1'>Interactions with Chain F</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_f/1'>Interactions with Chain F</scene>

-	'''F''' ~~is bonded to~~ four subunits, '''A''', '''G''', '''L''', and '''E''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''F''' interacts with four subunits, '''A''', '''G''', '''L''', and '''E'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_g/1'>Interactions with Chain G</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_g/1'>Interactions with Chain G</scene>

-	'''G''' ~~is bonded to~~ four subunits, '''A''', '''H''', '''L''', and '''F''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''G''' interacts with four subunits, '''A''', '''H''', '''L''', and '''F'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_h/1'>Interactions with Chain H</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_h/1'>Interactions with Chain H</scene>

-	'''H''' ~~is bonded to~~ four subunits, '''A''', '''B''', '''G''', and '''L''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''H''' interacts with four subunits, '''A''', '''B''', '''G''', and '''L'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_i/1'>Interactions with Chain I</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_i/1'>Interactions with Chain I</scene>

-	'''I''' ~~is bonded to~~ four subunits, '''B''', '''H''', '''C''', and '''J''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''I''' interacts with four subunits, '''B''', '''H''', '''C''', and '''J'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_j/1'>Interactions with Chain J</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_j/1'>Interactions with Chain J</scene>

-	'''J''' ~~is bonded to~~ four subunits, '''I''', '''C''', '''D''', and '''K''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''J''' interacts with four subunits, '''I''', '''C''', '''D''', and '''K'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_k/1'>Interactions with Chain K</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_k/1'>Interactions with Chain K</scene>

-	'''K''' ~~is bonded to~~ four subunits, '''E''', '''L''', '''J''', and '''D''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''K''' interacts with four subunits, '''E''', '''L''', '''J''', and '''D'''.

	<scene name='User:Kay_Owosela/Interactions_with_chain_l/1'>Interactions with Chain L</scene>		<scene name='User:Kay_Owosela/Interactions_with_chain_l/1'>Interactions with Chain L</scene>

-	'''L''' ~~is bonded to~~ four subunits, '''E''', '''F''', '''A''', and '''G''' ~~through hydrogen bonds and non-bonding interactions~~	+	'''L''' interacts with four subunits, '''E''', '''F''', '''A''', and '''G'''.

	= Active Site =		= Active Site =