User:Wayne Decatur/Suppression of RNA Silencing by Viruses - Revision history

Wayne Decatur at 18:53, 26 September 2010

Wayne Decatur — Sun, 26 Sep 2010 18:53:09 GMT

←Older revision		Revision as of 18:53, 26 September 2010
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	==Overview==		==Overview==
-	Andrew Z. Fire and Craig C. Mello shared [http://nobelprize.org/nobel_prizes/medicine/laureates/2006/ the 2006 Nobel Prize in Medicine or Physiology] for their discovery of [[RNA interference]] - gene silencing by double-stranded RNA.<br>	+	Andrew Z. Fire and Craig C. Mello shared [http://nobelprize.org/nobel_prizes/medicine/laureates/2006/ the 2006 Nobel Prize in Medicine or Physiology] for their discovery of [[RNA Interference\|RNA interference]] - gene silencing by double-stranded RNA.<br>

	RNA interference (RNAi) (also known as [http://en.wikipedia.org/wiki/Post-transcriptional_gene_silencing post-transcriptional gene silencing (PTGS)] or [http://en.wikipedia.org/wiki/RNA_Silencing RNA silencing]) is an evolutionarily conserved cellular response to the presence of double-stranded (ds) RNA that functions as a gene inactivation system in many eukaryotes and relies on tiny RNAs as the targeting molecules. One function of RNA silencing is to act in surveillance against molecular parasites, such as viruses, several of which rely on double-stranded RNA for replication. Viruses have developed mechanisms to counteract RNAi by providing proteins that sequester the tiny [http://en.wikipedia.org/wiki/Small_interfering_RNA silencing RNAs (siRNAs)] targeted against viral RNAs.<br>		RNA interference (RNAi) (also known as [http://en.wikipedia.org/wiki/Post-transcriptional_gene_silencing post-transcriptional gene silencing (PTGS)] or [http://en.wikipedia.org/wiki/RNA_Silencing RNA silencing]) is an evolutionarily conserved cellular response to the presence of double-stranded (ds) RNA that functions as a gene inactivation system in many eukaryotes and relies on tiny RNAs as the targeting molecules. One function of RNA silencing is to act in surveillance against molecular parasites, such as viruses, several of which rely on double-stranded RNA for replication. Viruses have developed mechanisms to counteract RNAi by providing proteins that sequester the tiny [http://en.wikipedia.org/wiki/Small_interfering_RNA silencing RNAs (siRNAs)] targeted against viral RNAs.<br>

Wayne Decatur at 18:52, 26 September 2010

Wayne Decatur — Sun, 26 Sep 2010 18:52:07 GMT

←Older revision		Revision as of 18:52, 26 September 2010
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	==Overview==		==Overview==
-	Andrew Z. Fire and Craig C. Mello shared [http://nobelprize.org/nobel_prizes/medicine/laureates/2006/ the 2006 Nobel Prize in Medicine or Physiology] for their discovery of [~~http://en.wikipedia.org/wiki/RNA_interference~~ RNA interference] - gene silencing by double-stranded RNA.<br>	+	Andrew Z. Fire and Craig C. Mello shared [http://nobelprize.org/nobel_prizes/medicine/laureates/2006/ the 2006 Nobel Prize in Medicine or Physiology] for their discovery of [[RNA interference]] - gene silencing by double-stranded RNA.<br>

	RNA interference (RNAi) (also known as [http://en.wikipedia.org/wiki/Post-transcriptional_gene_silencing post-transcriptional gene silencing (PTGS)] or [http://en.wikipedia.org/wiki/RNA_Silencing RNA silencing]) is an evolutionarily conserved cellular response to the presence of double-stranded (ds) RNA that functions as a gene inactivation system in many eukaryotes and relies on tiny RNAs as the targeting molecules. One function of RNA silencing is to act in surveillance against molecular parasites, such as viruses, several of which rely on double-stranded RNA for replication. Viruses have developed mechanisms to counteract RNAi by providing proteins that sequester the tiny [http://en.wikipedia.org/wiki/Small_interfering_RNA silencing RNAs (siRNAs)] targeted against viral RNAs.<br>		RNA interference (RNAi) (also known as [http://en.wikipedia.org/wiki/Post-transcriptional_gene_silencing post-transcriptional gene silencing (PTGS)] or [http://en.wikipedia.org/wiki/RNA_Silencing RNA silencing]) is an evolutionarily conserved cellular response to the presence of double-stranded (ds) RNA that functions as a gene inactivation system in many eukaryotes and relies on tiny RNAs as the targeting molecules. One function of RNA silencing is to act in surveillance against molecular parasites, such as viruses, several of which rely on double-stranded RNA for replication. Viruses have developed mechanisms to counteract RNAi by providing proteins that sequester the tiny [http://en.wikipedia.org/wiki/Small_interfering_RNA silencing RNAs (siRNAs)] targeted against viral RNAs.<br>

Wayne Decatur: editing overview

Wayne Decatur — Wed, 02 Jun 2010 14:48:24 GMT

editing overview

←Older revision		Revision as of 14:48, 2 June 2010
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	For a general introduction to RNA interference, see [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=rna%20interference&rid=mboc4.section.1363#1399 the pertinent section] in [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4 Molecular Biology of the Cell by Alberts et al.] or [http://www.hhmi.org/biointeractive/rna/rnai/index.html the Howard Hughes Medical Institute interactive online resource on the RNAi mechanism and overview of key scientific findings] or [http://www.nature.com/focus/rnai/animations/index.html an animation from Nature Publishing Group on the mechanism of RNA Interference].		For a general introduction to RNA interference, see [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=rna%20interference&rid=mboc4.section.1363#1399 the pertinent section] in [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4 Molecular Biology of the Cell by Alberts et al.] or [http://www.hhmi.org/biointeractive/rna/rnai/index.html the Howard Hughes Medical Institute interactive online resource on the RNAi mechanism and overview of key scientific findings] or [http://www.nature.com/focus/rnai/animations/index.html an animation from Nature Publishing Group on the mechanism of RNA Interference].

-	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. ~~The~~ three ~~different~~ proteins in these examples ~~bind~~ to double stranded RNA ~~by three different mechanisms~~: [[Tomato aspermy virus protein 2b Suppression of RNA Silencing\|one]] to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] ~~using~~ "molecular calipers". ~~Separate in-depth~~ entries for each of these ~~studies exist in Proteopedia~~:	+	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. Interestingly, the three proteins in these examples each employ a unique solution to bind the double stranded silencing RNA: [[Tomato aspermy virus protein 2b Suppression of RNA Silencing\|one]] interacts with the major groove, [[Flock house virus B2 protein Suppression of RNA Silencing\|one]] interacts mainly with the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] uses "molecular calipers" to measure the size of the silecing RNA. In Proteopedia, there are separate detailed entries for each of these structures:

	::::::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]		::::::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]

Wayne Decatur at 14:42, 2 June 2010

Wayne Decatur — Wed, 02 Jun 2010 14:42:08 GMT

←Older revision		Revision as of 14:42, 2 June 2010
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	For a general introduction to RNA interference, see [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=rna%20interference&rid=mboc4.section.1363#1399 the pertinent section] in [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4 Molecular Biology of the Cell by Alberts et al.] or [http://www.hhmi.org/biointeractive/rna/rnai/index.html the Howard Hughes Medical Institute interactive online resource on the RNAi mechanism and overview of key scientific findings] or [http://www.nature.com/focus/rnai/animations/index.html an animation from Nature Publishing Group on the mechanism of RNA Interference].		For a general introduction to RNA interference, see [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=rna%20interference&rid=mboc4.section.1363#1399 the pertinent section] in [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4 Molecular Biology of the Cell by Alberts et al.] or [http://www.hhmi.org/biointeractive/rna/rnai/index.html the Howard Hughes Medical Institute interactive online resource on the RNAi mechanism and overview of key scientific findings] or [http://www.nature.com/focus/rnai/animations/index.html an animation from Nature Publishing Group on the mechanism of RNA Interference].

-	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:	+	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: [[Tomato aspermy virus protein 2b Suppression of RNA Silencing\|one]] to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:

	::::::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]		::::::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]

Wayne Decatur at 14:41, 2 June 2010

Wayne Decatur — Wed, 02 Jun 2010 14:41:01 GMT

←Older revision		Revision as of 14:41, 2 June 2010
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	\|<applet load='2zi0' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Flock_house_virus_B2_protein_Suppression_of_RNA_Silencing/B2view1/4' caption='[[Flock house virus B2 protein Suppression of RNA Silencing\|Flock house virus B2 protein bound to siRNA]]' />		\|<applet load='2zi0' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Flock_house_virus_B2_protein_Suppression_of_RNA_Silencing/B2view1/4' caption='[[Flock house virus B2 protein Suppression of RNA Silencing\|Flock house virus B2 protein bound to siRNA]]' />
	\|}		\|}
		+
		+	<p> </p>
		+
		+	<p> </p>

	==Related Structures and Topics==		==Related Structures and Topics==

Wayne Decatur: fixing indents still

Wayne Decatur — Wed, 02 Jun 2010 14:39:32 GMT

fixing indents still

←Older revision		Revision as of 14:39, 2 June 2010
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	For a general introduction to RNA interference, see [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=rna%20interference&rid=mboc4.section.1363#1399 the pertinent section] in [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4 Molecular Biology of the Cell by Alberts et al.] or [http://www.hhmi.org/biointeractive/rna/rnai/index.html the Howard Hughes Medical Institute interactive online resource on the RNAi mechanism and overview of key scientific findings] or [http://www.nature.com/focus/rnai/animations/index.html an animation from Nature Publishing Group on the mechanism of RNA Interference].		For a general introduction to RNA interference, see [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=rna%20interference&rid=mboc4.section.1363#1399 the pertinent section] in [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4 Molecular Biology of the Cell by Alberts et al.] or [http://www.hhmi.org/biointeractive/rna/rnai/index.html the Howard Hughes Medical Institute interactive online resource on the RNAi mechanism and overview of key scientific findings] or [http://www.nature.com/focus/rnai/animations/index.html an animation from Nature Publishing Group on the mechanism of RNA Interference].
-

	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:		Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:

-	~~:::~~::::::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]	+	::::::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]
-	~~:::~~::::::*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]	+	::::::*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
-	~~:::~~::::::*[[Flock house virus B2 protein Suppression of RNA Silencing]]	+	::::::*[[Flock house virus B2 protein Suppression of RNA Silencing]]
	<p></p>		<p></p>

Wayne Decatur: tweaking indents

Wayne Decatur — Wed, 02 Jun 2010 14:38:16 GMT

tweaking indents

←Older revision		Revision as of 14:38, 2 June 2010
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	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:		Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:

-	:::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]	+	:::::::::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]
-	:::*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]	+	:::::::::*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
-	:::*[[Flock house virus B2 protein Suppression of RNA Silencing]]	+	:::::::::*[[Flock house virus B2 protein Suppression of RNA Silencing]]
	<p></p>		<p></p>

Wayne Decatur: still fixing overview

Wayne Decatur — Wed, 02 Jun 2010 14:37:30 GMT

still fixing overview

←Older revision		Revision as of 14:37, 2 June 2010
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	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:		Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:

-	*[[Plant Viral Protein p19 Suppression of RNA Silencing]]	+	:::*[[Plant Viral Protein p19 Suppression of RNA Silencing]]
-	*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]	+	:::*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
-	*[[Flock house virus B2 protein Suppression of RNA Silencing]]	+	:::*[[Flock house virus B2 protein Suppression of RNA Silencing]]
	<p></p>		<p></p>

-	==Related Structures and Topics==
	{\| style="float:right;"		{\| style="float:right;"
	\| <applet load='1rpu' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2' caption='[[Plant Viral Protein p19 Suppression of RNA Silencing\|Carnation italian ringspot virus p19 bound to siRNA]]' />		\| <applet load='1rpu' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2' caption='[[Plant Viral Protein p19 Suppression of RNA Silencing\|Carnation italian ringspot virus p19 bound to siRNA]]' />
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	\|<applet load='2zi0' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Flock_house_virus_B2_protein_Suppression_of_RNA_Silencing/B2view1/4' caption='[[Flock house virus B2 protein Suppression of RNA Silencing\|Flock house virus B2 protein bound to siRNA]]' />		\|<applet load='2zi0' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Flock_house_virus_B2_protein_Suppression_of_RNA_Silencing/B2view1/4' caption='[[Flock house virus B2 protein Suppression of RNA Silencing\|Flock house virus B2 protein bound to siRNA]]' />
	\|}		\|}
		+
		+	==Related Structures and Topics==
	*[[Plant Viral Protein p19 Suppression of RNA Silencing]]		*[[Plant Viral Protein p19 Suppression of RNA Silencing]]
	*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]		*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]

Wayne Decatur: fixing overview

Wayne Decatur — Wed, 02 Jun 2010 14:34:34 GMT

fixing overview

←Older revision		Revision as of 14:34, 2 June 2010
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	</imagemap>		</imagemap>

-	==~~Background~~==	+	==Overview==
	Andrew Z. Fire and Craig C. Mello shared [http://nobelprize.org/nobel_prizes/medicine/laureates/2006/ the 2006 Nobel Prize in Medicine or Physiology] for their discovery of [http://en.wikipedia.org/wiki/RNA_interference RNA interference] - gene silencing by double-stranded RNA.<br>		Andrew Z. Fire and Craig C. Mello shared [http://nobelprize.org/nobel_prizes/medicine/laureates/2006/ the 2006 Nobel Prize in Medicine or Physiology] for their discovery of [http://en.wikipedia.org/wiki/RNA_interference RNA interference] - gene silencing by double-stranded RNA.<br>

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-	~~Several~~ structures ~~highlighted below~~ have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses.	+	Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. The three different proteins in these examples bind to double stranded RNA by three different mechanisms: one to the major groove, one to the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing\|one]] using "molecular calipers". Separate in-depth entries for each of these studies exist in Proteopedia:
		+
		+	*[[Plant Viral Protein p19 Suppression of RNA Silencing]]
		+	*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
		+	*[[Flock house virus B2 protein Suppression of RNA Silencing]]
	<p></p>		<p></p>

Wayne Decatur at 22:42, 20 December 2009

Wayne Decatur — Sun, 20 Dec 2009 22:42:58 GMT

←Older revision		Revision as of 22:42, 20 December 2009
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	<imagemap>		<imagemap>
	Image:Unremediated1rpuWithPolyview3D.png\|left\|90px\|alt=1rpu image		Image:Unremediated1rpuWithPolyview3D.png\|left\|90px\|alt=1rpu image
-	default [[~~User:Wayne Decatur/~~Plant Viral Protein p19 Suppression of RNA Silencing]]	+	default [[Plant Viral Protein p19 Suppression of RNA Silencing]]
	desc none		desc none
	</imagemap>		</imagemap>
	<imagemap>		<imagemap>
	Image:2zioWithPolyview3D.png\|left\|90px\|alt=2zio image		Image:2zioWithPolyview3D.png\|left\|90px\|alt=2zio image
-	default [[~~User:Wayne Decatur/~~Tomato aspermy virus protein 2b Suppression of RNA Silencing]]	+	default [[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
	desc none		desc none
	</imagemap>		</imagemap>
	<imagemap>		<imagemap>
	Image:2az0WithPolyview3D.png\|left\|90px\|alt=2az0 image		Image:2az0WithPolyview3D.png\|left\|90px\|alt=2az0 image
-	default [[~~User:Wayne Decatur/~~Flock house virus B2 protein Suppression of RNA Silencing]]	+	default [[Flock house virus B2 protein Suppression of RNA Silencing]]
	desc none		desc none
	</imagemap>		</imagemap>
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	==Related Structures and Topics==		==Related Structures and Topics==
	{\| style="float:right;"		{\| style="float:right;"
-	\| <applet load='1rpu' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2' caption='[[~~User:Wayne Decatur/~~Plant Viral Protein p19 Suppression of RNA Silencing\|Carnation italian ringspot virus p19 bound to siRNA]]' />	+	\| <applet load='1rpu' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2' caption='[[Plant Viral Protein p19 Suppression of RNA Silencing\|Carnation italian ringspot virus p19 bound to siRNA]]' />
	\|\|		\|\|
-	\| <applet load='1r9f' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Tomato_aspermy_virus_protein_2b_Suppression_of_RNA_Silencing/View1withtrps/2' caption='[[~~User:Wayne Decatur/~~Tomato aspermy virus protein 2b Suppression of RNA Silencing\|Tomato ~~bushy stunt~~ virus ~~p19~~ bound to siRNA]]' />	+	\| <applet load='1r9f' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Tomato_aspermy_virus_protein_2b_Suppression_of_RNA_Silencing/View1withtrps/2' caption='[[Tomato aspermy virus protein 2b Suppression of RNA Silencing\|Tomato aspermy virus protein 2b bound to siRNA]]' />
	\|\|		\|\|
-	\|<applet load='2zi0' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Flock_house_virus_B2_protein_Suppression_of_RNA_Silencing/B2view1/4' caption='[[~~User:Wayne Decatur/~~Flock house virus B2 protein Suppression of RNA Silencing\|~~Tomato aspermy~~ virus protein 2b bound to siRNA]]' />	+	\|<applet load='2zi0' size='150' frame='true' align='right' scene='User:Wayne_Decatur/Flock_house_virus_B2_protein_Suppression_of_RNA_Silencing/B2view1/4' caption='[[Flock house virus B2 protein Suppression of RNA Silencing\|Flock house virus B2 protein bound to siRNA]]' />
	\|}		\|}
-	*[[~~User:Wayne Decatur/Plant Viral Protein p19 Suppression of RNA Silencing\|~~Plant Viral Protein p19 Suppression of RNA Silencing]]	+	*[[Plant Viral Protein p19 Suppression of RNA Silencing]]
-	*[[~~User:Wayne Decatur/Tomato aspermy virus protein 2b Suppression of RNA Silencing\|~~Tomato aspermy virus protein 2b Suppression of RNA Silencing]]	+	*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
-	*[[~~User:Wayne Decatur/Flock house virus B2 protein Suppression of RNA Silencing\|~~Flock house virus B2 protein Suppression of RNA Silencing]]	+	*[[Flock house virus B2 protein Suppression of RNA Silencing]]
	*[[1rpu]] Carnation italian ringspot virus p19 bound to siRNA		*[[1rpu]] Carnation italian ringspot virus p19 bound to siRNA
	*[[1r9f]] Tomato bushy stunt virus p19 bound to siRNA		*[[1r9f]] Tomato bushy stunt virus p19 bound to siRNA